Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
694
Gene name Gene Name - the full gene name approved by the HGNC.
BTG anti-proliferation factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
BTG1
Synonyms (NCBI Gene) Gene synonyms aliases
APRO2
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q21.33
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein int
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028939 hsa-miR-26b-5p Microarray 19088304
MIRT041705 hsa-miR-484 CLASH 23622248
MIRT041705 hsa-miR-484 CLASH 23622248
MIRT053302 hsa-miR-372-3p Luciferase reporter assay, qRT-PCR, Western blot 22020335
MIRT053303 hsa-miR-373-3p Luciferase reporter assay, qRT-PCR, Western blot 22020335
Transcription factors
Transcription factor Regulation Reference
AR Repression 16281084
HLX Unknown 22897850
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003712 Function Transcription coregulator activity NAS 11420681
GO:0005515 Function Protein binding IPI 9712883, 9820826, 10617598, 11136725, 16189514, 20211142, 21900206, 27107012, 31515488, 32296183, 35512704
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 9820826, 11420681
GO:0005634 Component Nucleus IMP 11420681
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
109580 1130 ENSG00000133639
Protein
UniProt ID P62324
Protein name Protein BTG1 (B-cell translocation gene 1 protein)
Protein function Anti-proliferative protein.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07742 BTG 11 124 BTG family Family
Sequence
Sequence length 171
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  RNA degradation   FOXO-mediated transcription of cell cycle genes
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Coenzyme Q10 Deficiency Coenzyme Q10 levels N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 24272202, 28922388
Carcinoma Adenosquamous Associate 37650999
Carcinoma Hepatocellular Associate 25173640, 28603285, 31486488
Carcinoma Non Small Cell Lung Inhibit 24264312
Carcinoma Pancreatic Ductal Associate 29076521
Carcinoma Renal Cell Associate 25115181
Carcinoma Squamous Cell Associate 32457282
Dermatitis Atopic Associate 15370698
Endometriosis Associate 31324015
Esophageal Neoplasms Inhibit 24969561