Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6915
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Thromboxane A2 receptor |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TBXA2R |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BDPLT13, TXA2-R |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BDPLT13 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants enc |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Bleeding disorder |
Bleeding Disorder due to Defective Thromboxane A2 Receptor, Bleeding diathesis due to thromboxane synthesis deficiency |
rs121918444, rs398122372, rs398122373, rs773148506, rs1064797083, rs1064797085, rs1064797087, rs761749948 |
|
Platelet-type bleeding disorder |
Blood Platelet Disorders |
rs1560045738, rs70961716, rs142186404, rs121918035, rs121918444, rs760074158, rs2146873791, rs387907345, rs387907346, rs387907348, rs387907350, rs397989794, rs587777211, rs587777529, rs724159972, rs572295823, rs550565800, rs869320714, rs869320716, rs757188030, rs1057518838, rs1057518837, rs148051111, rs1555122100, rs1554724694, rs755459581, rs752492512, rs1592371840, rs747559032, rs778608263, rs148910227, rs3211901, rs1594755688, rs1594760036, rs1594760140, rs1594768463, rs1594771224, rs1594771270, rs551607784, rs774996406, rs200434813 View all (26 more) |
7929844, 19828703 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Asthma |
Asthma, Aspirin-Induced |
|
16502481, 20485159 |
ClinVar |
Bleeding Disorder |
bleeding diathesis due to thromboxane synthesis deficiency |
|
|
GenCC |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Adenocarcinoma of Lung |
Associate
|
23874428 |
Androgen Insensitivity Syndrome |
Associate
|
23279270 |
Arterial Occlusive Diseases |
Associate
|
19403042 |
Asthma |
Associate
|
15898979, 36936944, 37231900 |
Blood Platelet Disorders |
Associate
|
23279270, 24465800, 27641736, 28704403, 31389738, 32723322 |
Blood Platelet Disorders |
Stimulate
|
31389738 |
Cardiovascular Diseases |
Associate
|
24465800, 32723322, 35236104 |
Carotid Stenosis |
Associate
|
28704403, 30914039 |
Cerebral Infarction |
Associate
|
19403042, 27641736, 28704403, 30914039 |
Dental Plaque |
Associate
|
28704403 |
Drug Hypersensitivity |
Associate
|
37231900 |
Gastrointestinal Hemorrhage |
Associate
|
26830988 |
Hemorrhage |
Associate
|
24465800, 31389738 |
Hypertension |
Associate
|
24465800 |
Miosis |
Associate
|
36936944 |
Multiple Myeloma |
Associate
|
26724804 |
Myocardial Infarction |
Associate
|
15898979 |
Neoplasm Metastasis |
Associate
|
23874428 |
Oropharyngeal Neoplasms |
Associate
|
31969157 |
Prostatic Neoplasms |
Associate
|
21357687 |
Prostatitis |
Associate
|
27689401 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
31969157 |
Status Asthmaticus |
Associate
|
15898979, 36936944 |
Thrombocytopenia 1 |
Associate
|
31389738 |
Thrombosis |
Associate
|
24465800, 32467143, 39798965 |
Triple Negative Breast Neoplasms |
Associate
|
27487152 |
Vascular Diseases |
Associate
|
35236104 |
|