Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6909
Gene name Gene Name - the full gene name approved by the HGNC.	T-box transcription factor 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TBX2
Synonyms (NCBI Gene) Gene synonyms aliases	VETD
Disease Acronyms (UniProt) Disease acronyms from UniProt database	VETD
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q23.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1555877071	G>A	Uncertain-significance, pathogenic	Coding sequence variant, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022554	hsa-miR-124-3p	Microarray	18668037
MIRT037721	hsa-miR-744-5p	CLASH	23622248
MIRT616088	hsa-miR-6801-3p	HITS-CLIP	19536157
MIRT616087	hsa-miR-6810-3p	HITS-CLIP	19536157
MIRT616086	hsa-miR-331-3p	HITS-CLIP	19536157
MIRT616085	hsa-miR-4292	HITS-CLIP	19536157
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	19536157
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	19536157
MIRT616080	hsa-miR-8089	HITS-CLIP	19536157
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	19536157
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	19536157
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	19536157
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	19536157
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616088	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT616087	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT616086	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616088	hsa-miR-6801-3p	HITS-CLIP	19536157
MIRT616087	hsa-miR-6810-3p	HITS-CLIP	19536157
MIRT616086	hsa-miR-331-3p	HITS-CLIP	19536157
MIRT616085	hsa-miR-4292	HITS-CLIP	19536157
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	19536157
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	19536157
MIRT616080	hsa-miR-8089	HITS-CLIP	19536157
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	19536157
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	19536157
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	19536157
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	19536157
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT616088	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT616087	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT616086	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT616085	hsa-miR-4292	HITS-CLIP	23824327
MIRT616084	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT616083	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616082	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT616081	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT616080	hsa-miR-8089	HITS-CLIP	23824327
MIRT616079	hsa-miR-3144-5p	HITS-CLIP	23824327
MIRT616078	hsa-miR-3191-3p	HITS-CLIP	23824327
MIRT616077	hsa-miR-4652-5p	HITS-CLIP	23824327
MIRT616076	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT616075	hsa-miR-6810-5p	HITS-CLIP	23824327
MIRT616074	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT616073	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT1415159	hsa-miR-1178	CLIP-seq
MIRT1415160	hsa-miR-1203	CLIP-seq
MIRT1415161	hsa-miR-1207-5p	CLIP-seq
MIRT1415162	hsa-miR-1285	CLIP-seq
MIRT1415163	hsa-miR-1292	CLIP-seq
MIRT1415164	hsa-miR-146b-3p	CLIP-seq
MIRT1415165	hsa-miR-153	CLIP-seq
MIRT1415166	hsa-miR-15a	CLIP-seq
MIRT1415167	hsa-miR-15b	CLIP-seq
MIRT1415168	hsa-miR-16	CLIP-seq
MIRT1415169	hsa-miR-1909	CLIP-seq
MIRT1415170	hsa-miR-195	CLIP-seq
MIRT1415171	hsa-miR-21	CLIP-seq
MIRT1415172	hsa-miR-214	CLIP-seq
MIRT1415173	hsa-miR-2861	CLIP-seq
MIRT1415174	hsa-miR-296-5p	CLIP-seq
MIRT1415175	hsa-miR-3160-5p	CLIP-seq
MIRT1415176	hsa-miR-3187-5p	CLIP-seq
MIRT1415177	hsa-miR-3192	CLIP-seq
MIRT1415178	hsa-miR-3193	CLIP-seq
MIRT1415179	hsa-miR-320a	CLIP-seq
MIRT1415180	hsa-miR-320b	CLIP-seq
MIRT1415181	hsa-miR-320c	CLIP-seq
MIRT1415182	hsa-miR-320d	CLIP-seq
MIRT1415183	hsa-miR-324-5p	CLIP-seq
MIRT1415184	hsa-miR-326	CLIP-seq
MIRT1415185	hsa-miR-330-5p	CLIP-seq
MIRT1415186	hsa-miR-338-3p	CLIP-seq
MIRT1415187	hsa-miR-338-5p	CLIP-seq
MIRT1415188	hsa-miR-361-3p	CLIP-seq
MIRT1415189	hsa-miR-3618	CLIP-seq
MIRT1415190	hsa-miR-3619-5p	CLIP-seq
MIRT1415191	hsa-miR-3646	CLIP-seq
MIRT1415192	hsa-miR-3662	CLIP-seq
MIRT1415193	hsa-miR-378g	CLIP-seq
MIRT1415194	hsa-miR-3940-3p	CLIP-seq
MIRT1415195	hsa-miR-3941	CLIP-seq
MIRT1415196	hsa-miR-424	CLIP-seq
MIRT1415197	hsa-miR-4314	CLIP-seq
MIRT1415198	hsa-miR-4315	CLIP-seq
MIRT1415199	hsa-miR-4429	CLIP-seq
MIRT1415200	hsa-miR-4471	CLIP-seq
MIRT1415201	hsa-miR-448	CLIP-seq
MIRT1415202	hsa-miR-4486	CLIP-seq
MIRT1415203	hsa-miR-4514	CLIP-seq
MIRT1415204	hsa-miR-4520a-5p	CLIP-seq
MIRT1415205	hsa-miR-4520b-5p	CLIP-seq
MIRT1415206	hsa-miR-4530	CLIP-seq
MIRT1415207	hsa-miR-4646-5p	CLIP-seq
MIRT1415208	hsa-miR-466	CLIP-seq
MIRT1415209	hsa-miR-4672	CLIP-seq
MIRT1415210	hsa-miR-4685-5p	CLIP-seq
MIRT1415211	hsa-miR-4688	CLIP-seq
MIRT1415212	hsa-miR-4691-5p	CLIP-seq
MIRT1415213	hsa-miR-4692	CLIP-seq
MIRT1415214	hsa-miR-4699-3p	CLIP-seq
MIRT1415215	hsa-miR-4713-5p	CLIP-seq
MIRT1415216	hsa-miR-4718	CLIP-seq
MIRT1415217	hsa-miR-4719	CLIP-seq
MIRT1415218	hsa-miR-4731-3p	CLIP-seq
MIRT1415219	hsa-miR-4736	CLIP-seq
MIRT1415220	hsa-miR-4763-3p	CLIP-seq
MIRT1415221	hsa-miR-4778-5p	CLIP-seq
MIRT1415222	hsa-miR-4790-5p	CLIP-seq
MIRT1415223	hsa-miR-4801	CLIP-seq
MIRT1415224	hsa-miR-486-3p	CLIP-seq
MIRT1415225	hsa-miR-486-5p	CLIP-seq
MIRT1415226	hsa-miR-497	CLIP-seq
MIRT1415227	hsa-miR-544b	CLIP-seq
MIRT1415228	hsa-miR-578	CLIP-seq
MIRT1415229	hsa-miR-582-3p	CLIP-seq
MIRT1415230	hsa-miR-590-5p	CLIP-seq
MIRT1415231	hsa-miR-612	CLIP-seq
MIRT1415232	hsa-miR-617	CLIP-seq
MIRT1415233	hsa-miR-720	CLIP-seq
MIRT1415234	hsa-miR-760	CLIP-seq
MIRT1415235	hsa-miR-761	CLIP-seq
MIRT1415236	hsa-miR-939	CLIP-seq
MIRT1415159	hsa-miR-1178	CLIP-seq
MIRT2124554	hsa-miR-1180	CLIP-seq
MIRT2124555	hsa-miR-1184	CLIP-seq
MIRT2124556	hsa-miR-1202	CLIP-seq
MIRT2124557	hsa-miR-1207-3p	CLIP-seq
MIRT1415161	hsa-miR-1207-5p	CLIP-seq
MIRT2124558	hsa-miR-1224-3p	CLIP-seq
MIRT2124559	hsa-miR-1236	CLIP-seq
MIRT2124560	hsa-miR-1260	CLIP-seq
MIRT2124561	hsa-miR-1260b	CLIP-seq
MIRT2124562	hsa-miR-1280	CLIP-seq
MIRT1415162	hsa-miR-1285	CLIP-seq
MIRT2124563	hsa-miR-1293	CLIP-seq
MIRT2124564	hsa-miR-1304	CLIP-seq
MIRT2124565	hsa-miR-134	CLIP-seq
MIRT1415164	hsa-miR-146b-3p	CLIP-seq
MIRT2124566	hsa-miR-1470	CLIP-seq
MIRT2124567	hsa-miR-150	CLIP-seq
MIRT1415166	hsa-miR-15a	CLIP-seq
MIRT1415167	hsa-miR-15b	CLIP-seq
MIRT1415168	hsa-miR-16	CLIP-seq
MIRT1415169	hsa-miR-1909	CLIP-seq
MIRT2124568	hsa-miR-1915	CLIP-seq
MIRT1415170	hsa-miR-195	CLIP-seq
MIRT1415172	hsa-miR-214	CLIP-seq
MIRT2124569	hsa-miR-2467-5p	CLIP-seq
MIRT1415173	hsa-miR-2861	CLIP-seq
MIRT1415174	hsa-miR-296-5p	CLIP-seq
MIRT2124570	hsa-miR-3118	CLIP-seq
MIRT2124571	hsa-miR-3120-3p	CLIP-seq
MIRT2124572	hsa-miR-3127-5p	CLIP-seq
MIRT2124573	hsa-miR-3130-5p	CLIP-seq
MIRT2124574	hsa-miR-3135b	CLIP-seq
MIRT2124575	hsa-miR-3150a-3p	CLIP-seq
MIRT2124576	hsa-miR-3175	CLIP-seq
MIRT2124577	hsa-miR-3180-5p	CLIP-seq
MIRT1415176	hsa-miR-3187-5p	CLIP-seq
MIRT1415177	hsa-miR-3192	CLIP-seq
MIRT1415178	hsa-miR-3193	CLIP-seq
MIRT1415183	hsa-miR-324-5p	CLIP-seq
MIRT1415184	hsa-miR-326	CLIP-seq
MIRT1415185	hsa-miR-330-5p	CLIP-seq
MIRT1415186	hsa-miR-338-3p	CLIP-seq
MIRT1415187	hsa-miR-338-5p	CLIP-seq
MIRT1415188	hsa-miR-361-3p	CLIP-seq
MIRT1415189	hsa-miR-3618	CLIP-seq
MIRT1415190	hsa-miR-3619-5p	CLIP-seq
MIRT2124578	hsa-miR-362-5p	CLIP-seq
MIRT1415191	hsa-miR-3646	CLIP-seq
MIRT2124579	hsa-miR-3657	CLIP-seq
MIRT1415192	hsa-miR-3662	CLIP-seq
MIRT2124580	hsa-miR-378	CLIP-seq
MIRT2124581	hsa-miR-378b	CLIP-seq
MIRT2124582	hsa-miR-378c	CLIP-seq
MIRT2124583	hsa-miR-378d	CLIP-seq
MIRT2124584	hsa-miR-378e	CLIP-seq
MIRT2124585	hsa-miR-378f	CLIP-seq
MIRT2124586	hsa-miR-378h	CLIP-seq
MIRT2124587	hsa-miR-378i	CLIP-seq
MIRT2124588	hsa-miR-3908	CLIP-seq
MIRT1415194	hsa-miR-3940-3p	CLIP-seq
MIRT2124589	hsa-miR-3972	CLIP-seq
MIRT2124590	hsa-miR-422a	CLIP-seq
MIRT1415196	hsa-miR-424	CLIP-seq
MIRT2124591	hsa-miR-4267	CLIP-seq
MIRT2124592	hsa-miR-4268	CLIP-seq
MIRT2124593	hsa-miR-4270	CLIP-seq
MIRT2124594	hsa-miR-4293	CLIP-seq
MIRT1415197	hsa-miR-4314	CLIP-seq
MIRT2124595	hsa-miR-4328	CLIP-seq
MIRT2124596	hsa-miR-4421	CLIP-seq
MIRT2124597	hsa-miR-4441	CLIP-seq
MIRT2124598	hsa-miR-4482	CLIP-seq
MIRT2124599	hsa-miR-4483	CLIP-seq
MIRT1415203	hsa-miR-4514	CLIP-seq
MIRT1415204	hsa-miR-4520a-5p	CLIP-seq
MIRT1415205	hsa-miR-4520b-5p	CLIP-seq
MIRT1415206	hsa-miR-4530	CLIP-seq
MIRT2124600	hsa-miR-4535	CLIP-seq
MIRT2124601	hsa-miR-4638-3p	CLIP-seq
MIRT1415207	hsa-miR-4646-5p	CLIP-seq
MIRT2124602	hsa-miR-4660	CLIP-seq
MIRT2124603	hsa-miR-4667-3p	CLIP-seq
MIRT1415209	hsa-miR-4672	CLIP-seq
MIRT1415210	hsa-miR-4685-5p	CLIP-seq
MIRT1415211	hsa-miR-4688	CLIP-seq
MIRT2124604	hsa-miR-4690-3p	CLIP-seq
MIRT1415212	hsa-miR-4691-5p	CLIP-seq
MIRT1415213	hsa-miR-4692	CLIP-seq
MIRT1415215	hsa-miR-4713-5p	CLIP-seq
MIRT2124605	hsa-miR-4715-3p	CLIP-seq
MIRT1415216	hsa-miR-4718	CLIP-seq
MIRT2124606	hsa-miR-4726-3p	CLIP-seq
MIRT1415219	hsa-miR-4736	CLIP-seq
MIRT1415220	hsa-miR-4763-3p	CLIP-seq
MIRT1415221	hsa-miR-4778-5p	CLIP-seq
MIRT1415224	hsa-miR-486-3p	CLIP-seq
MIRT1415225	hsa-miR-486-5p	CLIP-seq
MIRT2124607	hsa-miR-491-5p	CLIP-seq
MIRT2124608	hsa-miR-492	CLIP-seq
MIRT1415226	hsa-miR-497	CLIP-seq
MIRT2124609	hsa-miR-500b	CLIP-seq
MIRT2124610	hsa-miR-532-3p	CLIP-seq
MIRT2124611	hsa-miR-550a	CLIP-seq
MIRT1415229	hsa-miR-582-3p	CLIP-seq
MIRT2124612	hsa-miR-593	CLIP-seq
MIRT1415231	hsa-miR-612	CLIP-seq
MIRT1415232	hsa-miR-617	CLIP-seq
MIRT2124613	hsa-miR-642a	CLIP-seq
MIRT2124614	hsa-miR-646	CLIP-seq
MIRT2124615	hsa-miR-653	CLIP-seq
MIRT1415233	hsa-miR-720	CLIP-seq
MIRT1415234	hsa-miR-760	CLIP-seq
MIRT1415235	hsa-miR-761	CLIP-seq
MIRT2124616	hsa-miR-892a	CLIP-seq
MIRT1415236	hsa-miR-939	CLIP-seq
MIRT2124617	hsa-miR-943	CLIP-seq
MIRT2124564	hsa-miR-1304	CLIP-seq
MIRT2124578	hsa-miR-362-5p	CLIP-seq
MIRT2124609	hsa-miR-500b	CLIP-seq
MIRT2124615	hsa-miR-653	CLIP-seq

Show/Hide all(42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	11111039
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	11111039
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	11111039
GO:0001708	Process	Cell fate specification	IBA	21873635
GO:0001947	Process	Heart looping	ISS
GO:0003148	Process	Outflow tract septum morphogenesis	ISS
GO:0003151	Process	Outflow tract morphogenesis	ISS
GO:0003203	Process	Endocardial cushion morphogenesis	ISS
GO:0003256	Process	Regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	ISS
GO:0003677	Function	DNA binding	TAS	8530034
GO:0005515	Function	Protein binding	IPI	22002537, 32296183
GO:0005634	Component	Nucleus	IDA	15042700, 29726930
GO:0005667	Component	Transcription regulator complex	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0007219	Process	Notch signaling pathway	IEA
GO:0007521	Process	Muscle cell fate determination	ISS
GO:0007569	Process	Cell aging	IDA	11748239
GO:0008016	Process	Regulation of heart contraction	ISS
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	11748239
GO:0035050	Process	Embryonic heart tube development	ISS
GO:0035909	Process	Aorta morphogenesis	ISS
GO:0036302	Process	Atrioventricular canal development	ISS
GO:0042733	Process	Embryonic digit morphogenesis	ISS
GO:0043565	Function	Sequence-specific DNA binding	IDA	11111039
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IDA	10468588, 11111039, 29726930
GO:0048596	Process	Embryonic camera-type eye morphogenesis	ISS
GO:0048738	Process	Cardiac muscle tissue development	ISS
GO:0051145	Process	Smooth muscle cell differentiation	IEA
GO:0060021	Process	Roof of mouth development	IEA
GO:0060045	Process	Positive regulation of cardiac muscle cell proliferation	ISS
GO:0060465	Process	Pharynx development	ISS
GO:0060560	Process	Developmental growth involved in morphogenesis	IEA
GO:0060596	Process	Mammary placode formation	IEA
GO:0072105	Process	Ureteric peristalsis	IEA
GO:0090398	Process	Cellular senescence	IDA	22002537
GO:1901208	Process	Negative regulation of heart looping	ISS
GO:1901211	Process	Negative regulation of cardiac chamber formation	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
600747	11597	ENSG00000121068

Protein

UniProt ID

Q13207

Protein name

T-box transcription factor TBX2 (T-box protein 2)

Protein function

Transcription factor which acts as a transcriptional repressor (PubMed:11062467, PubMed:11111039, PubMed:12000749, PubMed:22844464, PubMed:30599067). May also function as a transcriptional activator (By similarity). Binds to the palindromic T si

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00907	T-box	107 → 287	T-box	Domain
PF12598	TBX	305 → 384	T-box transcription factor	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.

Sequence

MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGA
AAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHK
LGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADP
EMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRAN
DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLT
LPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADS
DPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLR
SLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFF
GPLGAGQPLFLHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPA
ASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAA
AAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPLP
ELALRKVGAPSRGALSPSGSAKEAANELQSIQRLVSGLESQRALSPGRESPK

Sequence length

712

Interactions

View interactions

Show/Hide Causal Diseases (12)

Disease term	Disease name	dbSNP ID	References
Causal
Atrial septal defect	Atrial Septal Defects	rs137852951, rs137852953, rs137852955, rs267607106, rs104893900, rs104893901, rs104893903, rs606231358, rs606231359, rs137852683, rs606231360, rs104893907, rs104894073, rs1585703301, rs104894074 View all (25 more)
Autism	Autistic behavior	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699 View all (8 more)
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)
Double outlet right ventricle	Double Outlet Right Ventricle	rs397514520, rs397514521
Hypertension	Hypertensive disease	rs13306026	27618447, 30487518
Hypoparathyroidism	Hypoparathyroidism	rs104893959, rs104894271, rs2134093224, rs104894272, rs6256, rs193922430, rs886037646, rs1554103179
Isolated somatotropin deficiency	Isolated somatotropin deficiency	rs797044450, rs71640277, rs863223306, rs2144738731, rs863223307, rs2144739370, rs863223309, rs863223310, rs137853223, rs2144739380, rs2144739391
Klippel feil syndrome	Klippel-Feil Syndrome	rs1567750527, rs772798486, rs713993044, rs864309489, rs1569172839
Neuroblastoma	Neuroblastoma	rs113994087, rs113994089, rs281864719, rs863225285, rs863225284, rs863225283, rs281864720, rs863225282, rs863225281, rs1057519698, rs915983602, rs1469271544	30127528
Patent ductus arteriosus	Patent ductus arteriosus	rs80338911, rs879253870, rs879253871, rs879255278, rs879255279, rs879253872
Scoliosis	Scoliosis, unspecified	rs1057518828, rs147296805, rs758163506, rs1555613564, rs1596852902, rs1596853067, rs1596853085
Vertebral anomalies and variable endocrine and t-cell dysfunction	VERTEBRAL ANOMALIES AND VARIABLE ENDOCRINE AND T-CELL DYSFUNCTION	rs886037717, rs1364709483	29726930

Show/Hide Unknown Diseases (5)

Disease term	Disease name	Source
Unknown
Vertebral anomalies and variable endocrine and T-cell dysfunction	vertebral anomalies and variable endocrine and T-cell dysfunction	GenCC
Gout	Gout	GWAS
Kidney Disease	Kidney Disease	GWAS
Coronary artery disease	Coronary artery disease	GWAS
Urolithiasis	Urolithiasis	GWAS

Show/Hide Text Mining Associations (45)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	36461127
Alveolar capillary dysplasia	Associate	37821225
Alzheimer Disease	Associate	36895559
Breast Neoplasms	Associate	11774034, 19469638, 24113180, 24742492, 30777332, 31253870, 35687133
Carcinoma Hepatocellular	Associate	28981677
Carcinoma Non Small Cell Lung	Inhibit	30866410
Carcinoma Non Small Cell Lung	Associate	36461127
Carcinoma Renal Cell	Associate	38070142
Carcinoma Squamous Cell	Associate	36478592
Cleft Palate	Associate	31204702
Colorectal Neoplasms	Associate	30451831
Conotruncal cardiac defects	Associate	30223900, 37406974
Coronary Artery Disease	Associate	35590109
Empty Sella Syndrome	Associate	35311234
Encephalitis Herpes Simplex	Associate	25394776
Endocrine System Diseases	Associate	35311234
Endometrial Neoplasms	Associate	27874289
Esophageal Squamous Cell Carcinoma	Stimulate	32271423
HEM dysplasia	Associate	35311234
Hodgkin Disease	Stimulate	34807923
Hypertension	Associate	37175507
Immune System Diseases	Associate	31204702
Keloid	Associate	35047146
Leukemia Lymphocytic Chronic B Cell	Associate	28572861
Lung Neoplasms	Inhibit	30866410
Melanoma	Associate	20534814, 24113180
Neoplasm Metastasis	Associate	19469638, 24742492, 29542868
Neoplasm Metastasis	Stimulate	32271423
Neoplasms	Associate	20534814, 23082988, 24113180, 24742492, 25394776, 28849151, 28971975, 29542868, 31870844, 32271423, 34440306, 36142793
Neoplasms	Inhibit	30866410, 35687133
Neuroblastoma	Associate	30451831, 31819055, 37584517
Non Muscle Invasive Bladder Neoplasms	Associate	25394776
Osteochondrodysplasias	Associate	35311234
Osteosarcoma	Associate	34440306
Pancreatic Neoplasms	Associate	19469638
Plagiocephaly and X linked mental retardation	Associate	35311234
Pre Eclampsia	Associate	35891763
Prostatic Neoplasms	Associate	28849151
Pulmonary Arterial Hypertension	Associate	37176017
Rhabdomyosarcoma	Associate	31988307
Spondylocostal dysostosis autosomal recessive	Associate	35311234
Urethritis	Associate	26663319
Urinary Bladder Neoplasms	Associate	25394776
Uterine Cervical Dysplasia	Associate	23388722
Ventricular Outflow Obstruction Right	Associate	30223900

TBX2 (T-box transcription factor 2)