Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	6902
Gene name	Tubulin folding cofactor A
Gene symbol	TBCA
Synonyms (NCBI Gene)	-
Chromosome	5
Chromosome location	5q14.1
Summary	The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubuli

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001495	hsa-miR-155-5p	pSILAC	18668040
MIRT001495	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT001495	hsa-miR-155-5p	Proteomics	18668040
MIRT664211	hsa-miR-3156-5p	HITS-CLIP	23824327
MIRT664210	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT664209	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT664208	hsa-miR-494-3p	HITS-CLIP	23824327
MIRT664207	hsa-miR-510-3p	HITS-CLIP	23824327
MIRT664206	hsa-miR-1264	HITS-CLIP	23824327
MIRT664205	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT664204	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT664203	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT664202	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT664201	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT664200	hsa-miR-5696	HITS-CLIP	23824327
MIRT664199	hsa-miR-579-3p	HITS-CLIP	23824327
MIRT664198	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT664197	hsa-miR-3685	HITS-CLIP	23824327
MIRT664196	hsa-miR-384	HITS-CLIP	23824327
MIRT664195	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT664194	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT648181	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT648180	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT664211	hsa-miR-3156-5p	HITS-CLIP	23824327
MIRT664210	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT664209	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT664208	hsa-miR-494-3p	HITS-CLIP	23824327
MIRT664207	hsa-miR-510-3p	HITS-CLIP	23824327
MIRT664206	hsa-miR-1264	HITS-CLIP	23824327
MIRT664205	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT664204	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT664203	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT664202	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT664201	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT664200	hsa-miR-5696	HITS-CLIP	23824327
MIRT664199	hsa-miR-579-3p	HITS-CLIP	23824327
MIRT664198	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT664197	hsa-miR-3685	HITS-CLIP	23824327
MIRT664196	hsa-miR-384	HITS-CLIP	23824327
MIRT664195	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT664194	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT648181	hsa-miR-186-5p	HITS-CLIP	23824327
MIRT648180	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT1413941	hsa-miR-23a	CLIP-seq
MIRT1413942	hsa-miR-23b	CLIP-seq
MIRT1413943	hsa-miR-23c	CLIP-seq
MIRT1413944	hsa-miR-380	CLIP-seq
MIRT1413945	hsa-miR-4495	CLIP-seq
MIRT1413946	hsa-miR-4705	CLIP-seq
MIRT1413947	hsa-miR-548ac	CLIP-seq
MIRT1413948	hsa-miR-548ae	CLIP-seq
MIRT1413949	hsa-miR-548aj	CLIP-seq
MIRT1413950	hsa-miR-548am	CLIP-seq
MIRT1413951	hsa-miR-548d-3p	CLIP-seq
MIRT1413952	hsa-miR-548x	CLIP-seq
MIRT1413953	hsa-miR-548z	CLIP-seq
MIRT1413954	hsa-miR-577	CLIP-seq
MIRT2124216	hsa-miR-155	CLIP-seq
MIRT2346532	hsa-miR-1246	CLIP-seq
MIRT2124216	hsa-miR-155	CLIP-seq
MIRT1413941	hsa-miR-23a	CLIP-seq
MIRT1413942	hsa-miR-23b	CLIP-seq
MIRT1413943	hsa-miR-23c	CLIP-seq
MIRT2346533	hsa-miR-3662	CLIP-seq
MIRT1413944	hsa-miR-380	CLIP-seq
MIRT2346534	hsa-miR-4274	CLIP-seq
MIRT1413945	hsa-miR-4495	CLIP-seq
MIRT2346535	hsa-miR-4519	CLIP-seq
MIRT2346536	hsa-miR-4694-3p	CLIP-seq
MIRT1413946	hsa-miR-4705	CLIP-seq
MIRT2346537	hsa-miR-4789-3p	CLIP-seq
MIRT2346538	hsa-miR-508-3p	CLIP-seq
MIRT2346539	hsa-miR-548aa	CLIP-seq
MIRT1413947	hsa-miR-548ac	CLIP-seq
MIRT1413948	hsa-miR-548ae	CLIP-seq
MIRT1413949	hsa-miR-548aj	CLIP-seq
MIRT1413950	hsa-miR-548am	CLIP-seq
MIRT1413951	hsa-miR-548d-3p	CLIP-seq
MIRT1413952	hsa-miR-548x	CLIP-seq
MIRT1413953	hsa-miR-548z	CLIP-seq
MIRT1413954	hsa-miR-577	CLIP-seq
MIRT2346540	hsa-miR-711	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	21044950, 32353859, 33060197
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	16130169
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0006457	Process	Protein folding	IBA
GO:0006457	Process	Protein folding	TAS	8706133
GO:0007021	Process	Tubulin complex assembly	IBA
GO:0007021	Process	Tubulin complex assembly	IEA
GO:0007023	Process	Post-chaperonin tubulin folding pathway	IEA
GO:0007023	Process	Post-chaperonin tubulin folding pathway	TAS	8706133
GO:0015630	Component	Microtubule cytoskeleton	IBA
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0015631	Function	Tubulin binding	IBA
GO:0048487	Function	Beta-tubulin binding	IEA
GO:0051087	Function	Protein-folding chaperone binding	TAS	8706133

MIM	HGNC	e!Ensembl
610058	11579	ENSG00000171530

O75347

Protein name

Tubulin-specific chaperone A (TCP1-chaperonin cofactor A) (Tubulin-folding cofactor A) (CFA)

Protein function

Tubulin-folding protein; involved in the early step of the tubulin folding pathway.

PDB

1H7C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02970	TBCA	9 → 95	Tubulin binding cofactor A	Domain

Sequence

MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYDIKKQAEILQES
RMMIPDCQRRLEAAYLDLQRILENEKDLEEAEEYKEARLVLDSVKLEA

Sequence length

108

Interactions

View interactions

TBCA (tubulin folding cofactor A)