Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
6874
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
TATA-box binding protein associated factor 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
TAF4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
MRD73, TAF(II)130, TAF(II)135, TAF2C, TAF2C1, TAF4A, TAFII-130, TAFII-135, TAFII130, TAFII135 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
MRD73 |
Chromosome
Chromosome number
|
20 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
20q13.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, |
UniProt ID |
O00268
|
Protein name |
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFII |
Protein function |
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TAT |
PDB |
1H3O
,
2P6V
,
6MZC
,
6MZD
,
6MZL
,
6MZM
,
7EDX
,
7EG7
,
7EG8
,
7EG9
,
7EGA
,
7EGB
,
7EGC
,
7EGD
,
7EGE
,
7EGF
,
7EGG
,
7EGI
,
7EGJ
,
7ENA
,
7ENC
,
8GXQ
,
8GXS
,
8WAK
,
8WAL
,
8WAN
,
8WAO
,
8WAP
,
8WAQ
,
8WAR
,
8WAS
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF07531
|
TAFH |
592 → 683 |
NHR1 homology to TAF |
Family |
PF05236
|
TAF4 |
834 → 1082 |
Transcription initiation factor TFIID component TAF4 family |
Family |
|
Sequence |
|
Sequence length |
1085 |
Interactions |
View interactions
|