Gene Gene information from NCBI Gene database.
Entrez ID 6836
Gene name Surfeit 4
Gene symbol SURF4
Synonyms (NCBI Gene)
ERV29
Chromosome 9
Chromosome location 9q34.2
Summary This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Go
miRNA miRNA information provided by mirtarbase database.
816
miRTarBase ID miRNA Experiments Reference
MIRT001831 hsa-miR-124-3p MicroarrayqRT-PCR 16549876
MIRT016415 hsa-miR-193b-3p Proteomics 21512034
MIRT001831 hsa-miR-124-3p qRT-PCR;Other 16549876
MIRT025424 hsa-miR-34a-5p Proteomics 21566225
MIRT050908 hsa-miR-17-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
42
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000139 Component Golgi membrane TAS
GO:0005515 Function Protein binding IPI 18287528, 21903422, 29251827
GO:0005783 Component Endoplasmic reticulum IBA
GO:0005783 Component Endoplasmic reticulum IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
185660 11476 ENSG00000148248
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O15260
Protein name Surfeit locus protein 4
Protein function Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion (PubMed:29643117, PubMed:30251625, PubMed:33186557). Acts as a cargo receptor for lipoproteins b
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02077 SURF4 4 269 SURF4 family Family
Sequence
Sequence length 269
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
COPI-dependent Golgi-to-ER retrograde traffic