Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	6830
Gene name	SPT6 homolog, histone chaperone and transcription elongation factor
Gene symbol	SUPT6H
Synonyms (NCBI Gene)	SPT6SPT6Hemb-5
Chromosome	17
Chromosome location	17q11.2

307

Show/Hide all (307)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047722	hsa-miR-10a-5p	CLASH	23622248
MIRT045937	hsa-miR-125b-5p	CLASH	23622248
MIRT039964	hsa-miR-615-3p	CLASH	23622248
MIRT039536	hsa-miR-652-3p	CLASH	23622248
MIRT1403612	hsa-miR-1207-5p	CLIP-seq
MIRT1403613	hsa-miR-1245b-5p	CLIP-seq
MIRT1403614	hsa-miR-1321	CLIP-seq
MIRT1403615	hsa-miR-1827	CLIP-seq
MIRT1403616	hsa-miR-2682	CLIP-seq
MIRT1403617	hsa-miR-3142	CLIP-seq
MIRT1403618	hsa-miR-3173-3p	CLIP-seq
MIRT1403619	hsa-miR-3184	CLIP-seq
MIRT1403620	hsa-miR-34a	CLIP-seq
MIRT1403621	hsa-miR-34c-5p	CLIP-seq
MIRT1403622	hsa-miR-3612	CLIP-seq
MIRT1403623	hsa-miR-423-5p	CLIP-seq
MIRT1403624	hsa-miR-4257	CLIP-seq
MIRT1403625	hsa-miR-4270	CLIP-seq
MIRT1403626	hsa-miR-4419a	CLIP-seq
MIRT1403627	hsa-miR-4441	CLIP-seq
MIRT1403628	hsa-miR-449a	CLIP-seq
MIRT1403629	hsa-miR-449b	CLIP-seq
MIRT1403630	hsa-miR-449c	CLIP-seq
MIRT1403631	hsa-miR-4510	CLIP-seq
MIRT1403632	hsa-miR-4650-5p	CLIP-seq
MIRT1403633	hsa-miR-4688	CLIP-seq
MIRT1403634	hsa-miR-4728-5p	CLIP-seq
MIRT1403635	hsa-miR-4739	CLIP-seq
MIRT1403636	hsa-miR-4755-3p	CLIP-seq
MIRT1403637	hsa-miR-4756-5p	CLIP-seq
MIRT1403638	hsa-miR-4763-3p	CLIP-seq
MIRT1403639	hsa-miR-4779	CLIP-seq
MIRT1403640	hsa-miR-486-3p	CLIP-seq
MIRT1403641	hsa-miR-650	CLIP-seq
MIRT1921734	hsa-miR-1236	CLIP-seq
MIRT1921735	hsa-miR-3064-3p	CLIP-seq
MIRT1921736	hsa-miR-4691-5p	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT1921734	hsa-miR-1236	CLIP-seq
MIRT1921735	hsa-miR-3064-3p	CLIP-seq
MIRT1921736	hsa-miR-4691-5p	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT2121001	hsa-miR-1182	CLIP-seq
MIRT1403612	hsa-miR-1207-5p	CLIP-seq
MIRT2121002	hsa-miR-1470	CLIP-seq
MIRT2121003	hsa-miR-1913	CLIP-seq
MIRT2121004	hsa-miR-1915	CLIP-seq
MIRT2121005	hsa-miR-1976	CLIP-seq
MIRT2121006	hsa-miR-3121-3p	CLIP-seq
MIRT2121007	hsa-miR-3175	CLIP-seq
MIRT2121008	hsa-miR-3183	CLIP-seq
MIRT2121009	hsa-miR-3189-5p	CLIP-seq
MIRT2121010	hsa-miR-323-5p	CLIP-seq
MIRT2121011	hsa-miR-324-3p	CLIP-seq
MIRT2121012	hsa-miR-324-5p	CLIP-seq
MIRT2121013	hsa-miR-331-3p	CLIP-seq
MIRT2121014	hsa-miR-3607-5p	CLIP-seq
MIRT2121015	hsa-miR-370	CLIP-seq
MIRT2121016	hsa-miR-4281	CLIP-seq
MIRT2121017	hsa-miR-4287	CLIP-seq
MIRT2121018	hsa-miR-4427	CLIP-seq
MIRT2121019	hsa-miR-4436a	CLIP-seq
MIRT2121020	hsa-miR-4446-5p	CLIP-seq
MIRT2121021	hsa-miR-4469	CLIP-seq
MIRT2121022	hsa-miR-4514	CLIP-seq
MIRT2121023	hsa-miR-4520a-3p	CLIP-seq
MIRT2121024	hsa-miR-4520b-3p	CLIP-seq
MIRT2121025	hsa-miR-4642	CLIP-seq
MIRT2121026	hsa-miR-4645-5p	CLIP-seq
MIRT2121027	hsa-miR-4663	CLIP-seq
MIRT2121028	hsa-miR-4667-3p	CLIP-seq
MIRT2121029	hsa-miR-4673	CLIP-seq
MIRT2121030	hsa-miR-4685-3p	CLIP-seq
MIRT2121031	hsa-miR-4687-3p	CLIP-seq
MIRT2121032	hsa-miR-4691-3p	CLIP-seq
MIRT2121033	hsa-miR-4692	CLIP-seq
MIRT2121034	hsa-miR-4710	CLIP-seq
MIRT2121035	hsa-miR-4711-5p	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT2121036	hsa-miR-4723-3p	CLIP-seq
MIRT2121037	hsa-miR-4726-3p	CLIP-seq
MIRT1403636	hsa-miR-4755-3p	CLIP-seq
MIRT2121038	hsa-miR-4755-5p	CLIP-seq
MIRT2121039	hsa-miR-4758-3p	CLIP-seq
MIRT1403638	hsa-miR-4763-3p	CLIP-seq
MIRT2121040	hsa-miR-516b	CLIP-seq
MIRT2121041	hsa-miR-552	CLIP-seq
MIRT2121042	hsa-miR-642a	CLIP-seq
MIRT2121043	hsa-miR-940	CLIP-seq
MIRT1403612	hsa-miR-1207-5p	CLIP-seq
MIRT2342993	hsa-miR-1229	CLIP-seq
MIRT1921734	hsa-miR-1236	CLIP-seq
MIRT1403613	hsa-miR-1245b-5p	CLIP-seq
MIRT2342994	hsa-miR-151-5p	CLIP-seq
MIRT2342995	hsa-miR-151b	CLIP-seq
MIRT1403615	hsa-miR-1827	CLIP-seq
MIRT2121004	hsa-miR-1915	CLIP-seq
MIRT1403616	hsa-miR-2682	CLIP-seq
MIRT2342996	hsa-miR-298	CLIP-seq
MIRT1403617	hsa-miR-3142	CLIP-seq
MIRT2121010	hsa-miR-323-5p	CLIP-seq
MIRT1403620	hsa-miR-34a	CLIP-seq
MIRT1403621	hsa-miR-34c-5p	CLIP-seq
MIRT2342997	hsa-miR-3616-3p	CLIP-seq
MIRT2342998	hsa-miR-3667-3p	CLIP-seq
MIRT2342999	hsa-miR-3925-5p	CLIP-seq
MIRT2121016	hsa-miR-4281	CLIP-seq
MIRT2343000	hsa-miR-4311	CLIP-seq
MIRT2121019	hsa-miR-4436a	CLIP-seq
MIRT2343001	hsa-miR-4436b-3p	CLIP-seq
MIRT1403628	hsa-miR-449a	CLIP-seq
MIRT1403629	hsa-miR-449b	CLIP-seq
MIRT1403630	hsa-miR-449c	CLIP-seq
MIRT1403632	hsa-miR-4650-5p	CLIP-seq
MIRT2343002	hsa-miR-4690-3p	CLIP-seq
MIRT2343003	hsa-miR-4690-5p	CLIP-seq
MIRT1921736	hsa-miR-4691-5p	CLIP-seq
MIRT2343004	hsa-miR-4698	CLIP-seq
MIRT2121034	hsa-miR-4710	CLIP-seq
MIRT2343005	hsa-miR-4721	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT2121037	hsa-miR-4726-3p	CLIP-seq
MIRT1403636	hsa-miR-4755-3p	CLIP-seq
MIRT1403638	hsa-miR-4763-3p	CLIP-seq
MIRT2343006	hsa-miR-548a-3p	CLIP-seq
MIRT2343007	hsa-miR-548e	CLIP-seq
MIRT2343008	hsa-miR-548f	CLIP-seq
MIRT2343009	hsa-miR-548g	CLIP-seq
MIRT2121041	hsa-miR-552	CLIP-seq
MIRT2343010	hsa-miR-563	CLIP-seq
MIRT2121007	hsa-miR-3175	CLIP-seq
MIRT2121014	hsa-miR-3607-5p	CLIP-seq
MIRT2121027	hsa-miR-4663	CLIP-seq
MIRT2121001	hsa-miR-1182	CLIP-seq
MIRT2121004	hsa-miR-1915	CLIP-seq
MIRT1921735	hsa-miR-3064-3p	CLIP-seq
MIRT2121010	hsa-miR-323-5p	CLIP-seq
MIRT2121016	hsa-miR-4281	CLIP-seq
MIRT2121019	hsa-miR-4436a	CLIP-seq
MIRT2121034	hsa-miR-4710	CLIP-seq
MIRT2121037	hsa-miR-4726-3p	CLIP-seq
MIRT2121040	hsa-miR-516b	CLIP-seq
MIRT2121041	hsa-miR-552	CLIP-seq
MIRT2121001	hsa-miR-1182	CLIP-seq
MIRT1403612	hsa-miR-1207-5p	CLIP-seq
MIRT1403613	hsa-miR-1245b-5p	CLIP-seq
MIRT1403614	hsa-miR-1321	CLIP-seq
MIRT2121002	hsa-miR-1470	CLIP-seq
MIRT1403615	hsa-miR-1827	CLIP-seq
MIRT2121003	hsa-miR-1913	CLIP-seq
MIRT2121004	hsa-miR-1915	CLIP-seq
MIRT2121005	hsa-miR-1976	CLIP-seq
MIRT2636948	hsa-miR-219-2-3p	CLIP-seq
MIRT1403616	hsa-miR-2682	CLIP-seq
MIRT1921735	hsa-miR-3064-3p	CLIP-seq
MIRT2121006	hsa-miR-3121-3p	CLIP-seq
MIRT2636949	hsa-miR-3135	CLIP-seq
MIRT1403617	hsa-miR-3142	CLIP-seq
MIRT1403618	hsa-miR-3173-3p	CLIP-seq
MIRT2121007	hsa-miR-3175	CLIP-seq
MIRT2121008	hsa-miR-3183	CLIP-seq
MIRT1403619	hsa-miR-3184	CLIP-seq
MIRT2121009	hsa-miR-3189-5p	CLIP-seq
MIRT2121010	hsa-miR-323-5p	CLIP-seq
MIRT2121011	hsa-miR-324-3p	CLIP-seq
MIRT2121012	hsa-miR-324-5p	CLIP-seq
MIRT1403620	hsa-miR-34a	CLIP-seq
MIRT1403621	hsa-miR-34c-5p	CLIP-seq
MIRT2121014	hsa-miR-3607-5p	CLIP-seq
MIRT1403622	hsa-miR-3612	CLIP-seq
MIRT2636950	hsa-miR-3670	CLIP-seq
MIRT2636951	hsa-miR-3922-5p	CLIP-seq
MIRT2342999	hsa-miR-3925-5p	CLIP-seq
MIRT1403623	hsa-miR-423-5p	CLIP-seq
MIRT1403624	hsa-miR-4257	CLIP-seq
MIRT1403625	hsa-miR-4270	CLIP-seq
MIRT2121016	hsa-miR-4281	CLIP-seq
MIRT2636952	hsa-miR-4286	CLIP-seq
MIRT2121017	hsa-miR-4287	CLIP-seq
MIRT2343000	hsa-miR-4311	CLIP-seq
MIRT1403626	hsa-miR-4419a	CLIP-seq
MIRT2636953	hsa-miR-4423-5p	CLIP-seq
MIRT2121018	hsa-miR-4427	CLIP-seq
MIRT2121019	hsa-miR-4436a	CLIP-seq
MIRT1403627	hsa-miR-4441	CLIP-seq
MIRT2121020	hsa-miR-4446-5p	CLIP-seq
MIRT2636954	hsa-miR-4457	CLIP-seq
MIRT2121021	hsa-miR-4469	CLIP-seq
MIRT1403628	hsa-miR-449a	CLIP-seq
MIRT1403629	hsa-miR-449b	CLIP-seq
MIRT1403630	hsa-miR-449c	CLIP-seq
MIRT1403631	hsa-miR-4510	CLIP-seq
MIRT2636955	hsa-miR-4529-5p	CLIP-seq
MIRT2121025	hsa-miR-4642	CLIP-seq
MIRT1403632	hsa-miR-4650-5p	CLIP-seq
MIRT2121027	hsa-miR-4663	CLIP-seq
MIRT2121028	hsa-miR-4667-3p	CLIP-seq
MIRT2636956	hsa-miR-4682	CLIP-seq
MIRT2121030	hsa-miR-4685-3p	CLIP-seq
MIRT2121031	hsa-miR-4687-3p	CLIP-seq
MIRT1403633	hsa-miR-4688	CLIP-seq
MIRT2343002	hsa-miR-4690-3p	CLIP-seq
MIRT2636957	hsa-miR-4704-3p	CLIP-seq
MIRT2121034	hsa-miR-4710	CLIP-seq
MIRT2121035	hsa-miR-4711-5p	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT2121036	hsa-miR-4723-3p	CLIP-seq
MIRT2121037	hsa-miR-4726-3p	CLIP-seq
MIRT1403634	hsa-miR-4728-5p	CLIP-seq
MIRT1403635	hsa-miR-4739	CLIP-seq
MIRT2636958	hsa-miR-4753-5p	CLIP-seq
MIRT1403636	hsa-miR-4755-3p	CLIP-seq
MIRT2121038	hsa-miR-4755-5p	CLIP-seq
MIRT1403637	hsa-miR-4756-5p	CLIP-seq
MIRT2121039	hsa-miR-4758-3p	CLIP-seq
MIRT1403638	hsa-miR-4763-3p	CLIP-seq
MIRT2636959	hsa-miR-4774-3p	CLIP-seq
MIRT1403639	hsa-miR-4779	CLIP-seq
MIRT1403640	hsa-miR-486-3p	CLIP-seq
MIRT2636960	hsa-miR-513b	CLIP-seq
MIRT2121040	hsa-miR-516b	CLIP-seq
MIRT2121041	hsa-miR-552	CLIP-seq
MIRT2343010	hsa-miR-563	CLIP-seq
MIRT2121042	hsa-miR-642a	CLIP-seq
MIRT1403641	hsa-miR-650	CLIP-seq
MIRT2636961	hsa-miR-941	CLIP-seq
MIRT2121001	hsa-miR-1182	CLIP-seq
MIRT1403612	hsa-miR-1207-5p	CLIP-seq
MIRT1403613	hsa-miR-1245b-5p	CLIP-seq
MIRT1403614	hsa-miR-1321	CLIP-seq
MIRT2121002	hsa-miR-1470	CLIP-seq
MIRT1403615	hsa-miR-1827	CLIP-seq
MIRT2121003	hsa-miR-1913	CLIP-seq
MIRT2121004	hsa-miR-1915	CLIP-seq
MIRT2121005	hsa-miR-1976	CLIP-seq
MIRT2636948	hsa-miR-219-2-3p	CLIP-seq
MIRT1403616	hsa-miR-2682	CLIP-seq
MIRT1921735	hsa-miR-3064-3p	CLIP-seq
MIRT2121006	hsa-miR-3121-3p	CLIP-seq
MIRT2636949	hsa-miR-3135	CLIP-seq
MIRT1403617	hsa-miR-3142	CLIP-seq
MIRT1403618	hsa-miR-3173-3p	CLIP-seq
MIRT2121007	hsa-miR-3175	CLIP-seq
MIRT2121008	hsa-miR-3183	CLIP-seq
MIRT1403619	hsa-miR-3184	CLIP-seq
MIRT2121009	hsa-miR-3189-5p	CLIP-seq
MIRT2121010	hsa-miR-323-5p	CLIP-seq
MIRT2121011	hsa-miR-324-3p	CLIP-seq
MIRT2121012	hsa-miR-324-5p	CLIP-seq
MIRT1403620	hsa-miR-34a	CLIP-seq
MIRT1403621	hsa-miR-34c-5p	CLIP-seq
MIRT2121014	hsa-miR-3607-5p	CLIP-seq
MIRT1403622	hsa-miR-3612	CLIP-seq
MIRT2636950	hsa-miR-3670	CLIP-seq
MIRT2636951	hsa-miR-3922-5p	CLIP-seq
MIRT2342999	hsa-miR-3925-5p	CLIP-seq
MIRT1403623	hsa-miR-423-5p	CLIP-seq
MIRT1403624	hsa-miR-4257	CLIP-seq
MIRT1403625	hsa-miR-4270	CLIP-seq
MIRT2121016	hsa-miR-4281	CLIP-seq
MIRT2636952	hsa-miR-4286	CLIP-seq
MIRT2121017	hsa-miR-4287	CLIP-seq
MIRT2343000	hsa-miR-4311	CLIP-seq
MIRT1403626	hsa-miR-4419a	CLIP-seq
MIRT2636953	hsa-miR-4423-5p	CLIP-seq
MIRT2121018	hsa-miR-4427	CLIP-seq
MIRT2121019	hsa-miR-4436a	CLIP-seq
MIRT1403627	hsa-miR-4441	CLIP-seq
MIRT2121020	hsa-miR-4446-5p	CLIP-seq
MIRT2636954	hsa-miR-4457	CLIP-seq
MIRT2121021	hsa-miR-4469	CLIP-seq
MIRT1403628	hsa-miR-449a	CLIP-seq
MIRT1403629	hsa-miR-449b	CLIP-seq
MIRT1403630	hsa-miR-449c	CLIP-seq
MIRT1403631	hsa-miR-4510	CLIP-seq
MIRT2636955	hsa-miR-4529-5p	CLIP-seq
MIRT2121025	hsa-miR-4642	CLIP-seq
MIRT1403632	hsa-miR-4650-5p	CLIP-seq
MIRT2121027	hsa-miR-4663	CLIP-seq
MIRT2121028	hsa-miR-4667-3p	CLIP-seq
MIRT2636956	hsa-miR-4682	CLIP-seq
MIRT2121030	hsa-miR-4685-3p	CLIP-seq
MIRT2121031	hsa-miR-4687-3p	CLIP-seq
MIRT1403633	hsa-miR-4688	CLIP-seq
MIRT2121034	hsa-miR-4710	CLIP-seq
MIRT2121035	hsa-miR-4711-5p	CLIP-seq
MIRT1921737	hsa-miR-4722-3p	CLIP-seq
MIRT2121036	hsa-miR-4723-3p	CLIP-seq
MIRT2121037	hsa-miR-4726-3p	CLIP-seq
MIRT1403634	hsa-miR-4728-5p	CLIP-seq
MIRT1403635	hsa-miR-4739	CLIP-seq
MIRT2636958	hsa-miR-4753-5p	CLIP-seq
MIRT1403636	hsa-miR-4755-3p	CLIP-seq
MIRT2121038	hsa-miR-4755-5p	CLIP-seq
MIRT1403637	hsa-miR-4756-5p	CLIP-seq
MIRT2121039	hsa-miR-4758-3p	CLIP-seq
MIRT1403638	hsa-miR-4763-3p	CLIP-seq
MIRT2636959	hsa-miR-4774-3p	CLIP-seq
MIRT1403639	hsa-miR-4779	CLIP-seq
MIRT1403640	hsa-miR-486-3p	CLIP-seq
MIRT2636960	hsa-miR-513b	CLIP-seq
MIRT2121040	hsa-miR-516b	CLIP-seq
MIRT2121041	hsa-miR-552	CLIP-seq
MIRT2343010	hsa-miR-563	CLIP-seq
MIRT2121042	hsa-miR-642a	CLIP-seq
MIRT1403641	hsa-miR-650	CLIP-seq
MIRT2636961	hsa-miR-941	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001825	Process	Blastocyst formation	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	10933715, 16273093, 17234882, 19141475, 21518874
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006139	Process	Nucleobase-containing compound metabolic process	IEA
GO:0006368	Process	Transcription elongation by RNA polymerase II	IBA
GO:0006368	Process	Transcription elongation by RNA polymerase II	IEA
GO:0006368	Process	Transcription elongation by RNA polymerase II	IMP	17234882
GO:0006397	Process	MRNA processing	IEA
GO:0008023	Component	Transcription elongation factor complex	IBA
GO:0008380	Process	RNA splicing	IEA
GO:0031491	Function	Nucleosome binding	IBA
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	IEA
GO:0034728	Process	Nucleosome organization	IBA
GO:0042393	Function	Histone binding	IBA
GO:0042393	Function	Histone binding	IDA	10933715
GO:0045191	Process	Regulation of isotype switching	IEA
GO:0045191	Process	Regulation of isotype switching	ISS
GO:0051028	Process	MRNA transport	IEA
GO:0051147	Process	Regulation of muscle cell differentiation	IEA
GO:0051147	Process	Regulation of muscle cell differentiation	ISS
GO:0140673	Process	Transcription elongation-coupled chromatin remodeling	IEA
GO:0140673	Process	Transcription elongation-coupled chromatin remodeling	IMP	23503590

MIM	HGNC	e!Ensembl
601333	11470	ENSG00000109111

Q7KZ85

Protein name

Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)

Protein function

Histone H3-H4 chaperone that plays a key role in the regulation of transcription elongation and mRNA processing. Enhances the transcription elongation by RNA polymerase II (RNAPII) and is also required for the efficient activation of transcripti

PDB

6GME , 6GMH , 6TED , 7OOP , 7OPC , 7OPD , 7UNC , 7UND , 8A3Y , 8OEU , 8OEV , 8OF0 , 9EGX , 9EGY , 9EGZ , 9EH0 , 9EH2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14632	SPT6_acidic	37 → 127	Acidic N-terminal SPT6	Family
PF14641	HTH_44	305 → 433	Helix-turn-helix DNA-binding domain of SPT6	Domain
PF14639	YqgF	775 → 931	Holliday-junction resolvase-like of SPT6	Domain
PF14635	HHH_7	935 → 1038		Domain
PF17674	HHH_9	1051 → 1138	HHH domain	Domain
PF00575	S1	1224 → 1282	S1 RNA binding domain	Domain
PF14633	SH2_2	1300 → 1514	SH2 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed.

Sequence

MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFIND
DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR
VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD
IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY
EYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQL
RSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIK
EALGFMRNQHFEVPFIAFYRKEYVEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKM
QAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQN
AAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFG
LTPEQFGENLRDSYQRHETEQFPAEPLELAKDYVCSQFPTPEAVLEGARYMVALQIAREP
LVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKICLAE
DEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQF
LYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIR
VLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFL
LNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSE
AEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYC
EFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTM
CHMGPKVFMNCAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESA
EDANPAGALEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTA
YRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQAIRNDETGLWQCPF
CQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVG
MTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMKRKQ
QRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQH
VDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDR
KKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGFRYRGQI
FPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMT
SQMFSAIAAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTPAQQPVATPLMTPS
YSYTTPSQPITTPQYHQLQASTTPQSAQAQPQPSSSSRQRQQQPKSNSHAAIDWGKMAEQ
WLQEKEAERRKQKQRLTPRPSPSPMIESTPMSIAGDATPLLDEMDR

Sequence length

1726

Interactions

View interactions

	Reactome
			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Aphasia Broca	Associate	36818472	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	39838298	★★★★★ ★☆☆☆☆ Found in Text Mining only
COVID 19	Associate	36818472	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	36852700	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	25748235	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	36852700	★★★★★ ★☆☆☆☆ Found in Text Mining only
Testicular Germ Cell Tumor	Associate	25748235	★★★★★ ★☆☆☆☆ Found in Text Mining only

SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor)