Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6746
Gene name Gene Name - the full gene name approved by the HGNC.	Signal sequence receptor subunit 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SSR2
Synonyms (NCBI Gene) Gene synonyms aliases	HSD25, TLAP, TRAP-BETA, TRAPB
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q22
Summary Summary of gene provided in NCBI Entrez Gene.	The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprote

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miRTarBase ID	miRNA	Experiments	Reference
MIRT045638	hsa-miR-149-5p	CLASH	23622248
MIRT045273	hsa-miR-186-5p	CLASH	23622248
MIRT042799	hsa-miR-339-5p	CLASH	23622248
MIRT042734	hsa-miR-345-5p	CLASH	23622248
MIRT042734	hsa-miR-345-5p	CLASH	23622248
MIRT040270	hsa-miR-615-3p	CLASH	23622248
MIRT698849	hsa-miR-876-5p	HITS-CLIP	23313552
MIRT698848	hsa-miR-3167	HITS-CLIP	23313552
MIRT698847	hsa-miR-6835-3p	HITS-CLIP	23313552
MIRT698846	hsa-miR-4662a-3p	HITS-CLIP	23313552
MIRT698845	hsa-miR-619-3p	HITS-CLIP	23313552
MIRT698844	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT698843	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT698842	hsa-miR-6128	HITS-CLIP	23313552
MIRT698841	hsa-miR-378j	HITS-CLIP	23313552
MIRT698840	hsa-miR-6839-5p	HITS-CLIP	23313552
MIRT698839	hsa-miR-5186	HITS-CLIP	23313552
MIRT698838	hsa-miR-6804-3p	HITS-CLIP	23313552
MIRT698837	hsa-miR-1289	HITS-CLIP	23313552
MIRT698836	hsa-miR-4294	HITS-CLIP	23313552
MIRT698835	hsa-miR-1290	HITS-CLIP	23313552
MIRT698834	hsa-miR-1299	HITS-CLIP	23313552
MIRT698833	hsa-miR-33a-5p	HITS-CLIP	23313552
MIRT698832	hsa-miR-33b-5p	HITS-CLIP	23313552
MIRT698831	hsa-miR-3978	HITS-CLIP	23313552
MIRT698830	hsa-miR-3198	HITS-CLIP	23313552
MIRT698829	hsa-miR-4309	HITS-CLIP	23313552
MIRT698828	hsa-miR-3658	HITS-CLIP	23313552
MIRT698827	hsa-miR-1185-5p	HITS-CLIP	23313552
MIRT698849	hsa-miR-876-5p	HITS-CLIP	23313552
MIRT698848	hsa-miR-3167	HITS-CLIP	23313552
MIRT698847	hsa-miR-6835-3p	HITS-CLIP	23313552
MIRT698846	hsa-miR-4662a-3p	HITS-CLIP	23313552
MIRT698845	hsa-miR-619-3p	HITS-CLIP	23313552
MIRT698844	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT698843	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT698842	hsa-miR-6128	HITS-CLIP	23313552
MIRT698841	hsa-miR-378j	HITS-CLIP	23313552
MIRT698840	hsa-miR-6839-5p	HITS-CLIP	23313552
MIRT698839	hsa-miR-5186	HITS-CLIP	23313552
MIRT698838	hsa-miR-6804-3p	HITS-CLIP	23313552
MIRT698837	hsa-miR-1289	HITS-CLIP	23313552
MIRT698836	hsa-miR-4294	HITS-CLIP	23313552
MIRT698835	hsa-miR-1290	HITS-CLIP	23313552
MIRT698834	hsa-miR-1299	HITS-CLIP	23313552
MIRT698833	hsa-miR-33a-5p	HITS-CLIP	23313552
MIRT698832	hsa-miR-33b-5p	HITS-CLIP	23313552
MIRT698831	hsa-miR-3978	HITS-CLIP	23313552
MIRT698830	hsa-miR-3198	HITS-CLIP	23313552
MIRT698829	hsa-miR-4309	HITS-CLIP	23313552
MIRT698828	hsa-miR-3658	HITS-CLIP	23313552
MIRT698827	hsa-miR-1185-5p	HITS-CLIP	23313552
MIRT1392589	hsa-miR-1202	CLIP-seq
MIRT1392590	hsa-miR-1253	CLIP-seq
MIRT1392591	hsa-miR-135a	CLIP-seq
MIRT1392592	hsa-miR-135b	CLIP-seq
MIRT1392593	hsa-miR-2278	CLIP-seq
MIRT1392594	hsa-miR-3065-3p	CLIP-seq
MIRT1392595	hsa-miR-3151	CLIP-seq
MIRT1392596	hsa-miR-3194-5p	CLIP-seq
MIRT1392597	hsa-miR-33a	CLIP-seq
MIRT1392598	hsa-miR-33b	CLIP-seq
MIRT1392599	hsa-miR-3677-5p	CLIP-seq
MIRT1392600	hsa-miR-3926	CLIP-seq
MIRT1392601	hsa-miR-3942-5p	CLIP-seq
MIRT1392602	hsa-miR-3972	CLIP-seq
MIRT1392603	hsa-miR-4257	CLIP-seq
MIRT1392604	hsa-miR-4436b-3p	CLIP-seq
MIRT1392605	hsa-miR-4661-3p	CLIP-seq
MIRT1392606	hsa-miR-4691-5p	CLIP-seq
MIRT1392607	hsa-miR-4703-5p	CLIP-seq
MIRT1392608	hsa-miR-4711-5p	CLIP-seq
MIRT1392609	hsa-miR-4768-3p	CLIP-seq
MIRT1392610	hsa-miR-4796-3p	CLIP-seq
MIRT1392611	hsa-miR-486-3p	CLIP-seq
MIRT1392612	hsa-miR-548s	CLIP-seq
MIRT1392613	hsa-miR-579	CLIP-seq
MIRT1392614	hsa-miR-645	CLIP-seq
MIRT1392615	hsa-miR-665	CLIP-seq
MIRT2117777	hsa-miR-1254	CLIP-seq
MIRT1392591	hsa-miR-135a	CLIP-seq
MIRT1392592	hsa-miR-135b	CLIP-seq
MIRT2117778	hsa-miR-205	CLIP-seq
MIRT1392593	hsa-miR-2278	CLIP-seq
MIRT2117779	hsa-miR-3116	CLIP-seq
MIRT1392595	hsa-miR-3151	CLIP-seq
MIRT2117780	hsa-miR-3158-3p	CLIP-seq
MIRT2117781	hsa-miR-3689a-3p	CLIP-seq
MIRT2117782	hsa-miR-3689c	CLIP-seq
MIRT2117783	hsa-miR-3910	CLIP-seq
MIRT2117784	hsa-miR-3922-5p	CLIP-seq
MIRT1392603	hsa-miR-4257	CLIP-seq
MIRT1392604	hsa-miR-4436b-3p	CLIP-seq
MIRT2117785	hsa-miR-4446-3p	CLIP-seq
MIRT2117786	hsa-miR-4492	CLIP-seq
MIRT2117787	hsa-miR-4498	CLIP-seq
MIRT1392605	hsa-miR-4661-3p	CLIP-seq
MIRT1392608	hsa-miR-4711-5p	CLIP-seq
MIRT1392609	hsa-miR-4768-3p	CLIP-seq
MIRT1392610	hsa-miR-4796-3p	CLIP-seq
MIRT1392611	hsa-miR-486-3p	CLIP-seq
MIRT2117788	hsa-miR-548an	CLIP-seq
MIRT2117789	hsa-miR-578	CLIP-seq
MIRT1392613	hsa-miR-579	CLIP-seq
MIRT2117790	hsa-miR-619	CLIP-seq
MIRT2117791	hsa-miR-635	CLIP-seq
MIRT1392614	hsa-miR-645	CLIP-seq
MIRT1392615	hsa-miR-665	CLIP-seq
MIRT2117792	hsa-miR-762	CLIP-seq
MIRT2117777	hsa-miR-1254	CLIP-seq
MIRT2339745	hsa-miR-125a-5p	CLIP-seq
MIRT2339746	hsa-miR-125b	CLIP-seq
MIRT2339747	hsa-miR-1273d	CLIP-seq
MIRT2339748	hsa-miR-1912	CLIP-seq
MIRT2117779	hsa-miR-3116	CLIP-seq
MIRT2339749	hsa-miR-3123	CLIP-seq
MIRT2339750	hsa-miR-365	CLIP-seq
MIRT2117781	hsa-miR-3689a-3p	CLIP-seq
MIRT2117782	hsa-miR-3689c	CLIP-seq
MIRT2339751	hsa-miR-4319	CLIP-seq
MIRT2339752	hsa-miR-4324	CLIP-seq
MIRT2339753	hsa-miR-4684-5p	CLIP-seq
MIRT2117789	hsa-miR-578	CLIP-seq
MIRT2117791	hsa-miR-635	CLIP-seq
MIRT2339754	hsa-miR-942	CLIP-seq
MIRT1392589	hsa-miR-1202	CLIP-seq
MIRT2339745	hsa-miR-125a-5p	CLIP-seq
MIRT2339746	hsa-miR-125b	CLIP-seq
MIRT1392591	hsa-miR-135a	CLIP-seq
MIRT1392592	hsa-miR-135b	CLIP-seq
MIRT1392594	hsa-miR-3065-3p	CLIP-seq
MIRT2339749	hsa-miR-3123	CLIP-seq
MIRT1392595	hsa-miR-3151	CLIP-seq
MIRT1392596	hsa-miR-3194-5p	CLIP-seq
MIRT2117783	hsa-miR-3910	CLIP-seq
MIRT2117784	hsa-miR-3922-5p	CLIP-seq
MIRT1392601	hsa-miR-3942-5p	CLIP-seq
MIRT1392602	hsa-miR-3972	CLIP-seq
MIRT1392603	hsa-miR-4257	CLIP-seq
MIRT2339751	hsa-miR-4319	CLIP-seq
MIRT2339752	hsa-miR-4324	CLIP-seq
MIRT1392607	hsa-miR-4703-5p	CLIP-seq
MIRT1392608	hsa-miR-4711-5p	CLIP-seq
MIRT1392611	hsa-miR-486-3p	CLIP-seq
MIRT2117788	hsa-miR-548an	CLIP-seq
MIRT1392614	hsa-miR-645	CLIP-seq
MIRT1392590	hsa-miR-1253	CLIP-seq
MIRT1392591	hsa-miR-135a	CLIP-seq
MIRT1392592	hsa-miR-135b	CLIP-seq
MIRT2117778	hsa-miR-205	CLIP-seq
MIRT1392593	hsa-miR-2278	CLIP-seq
MIRT2692047	hsa-miR-2467-5p	CLIP-seq
MIRT1392594	hsa-miR-3065-3p	CLIP-seq
MIRT1392595	hsa-miR-3151	CLIP-seq
MIRT2117780	hsa-miR-3158-3p	CLIP-seq
MIRT2692048	hsa-miR-3173-3p	CLIP-seq
MIRT1392597	hsa-miR-33a	CLIP-seq
MIRT1392598	hsa-miR-33b	CLIP-seq
MIRT1392599	hsa-miR-3677-5p	CLIP-seq
MIRT2117783	hsa-miR-3910	CLIP-seq
MIRT2117784	hsa-miR-3922-5p	CLIP-seq
MIRT1392600	hsa-miR-3926	CLIP-seq
MIRT1392603	hsa-miR-4257	CLIP-seq
MIRT1392604	hsa-miR-4436b-3p	CLIP-seq
MIRT2117785	hsa-miR-4446-3p	CLIP-seq
MIRT2117786	hsa-miR-4492	CLIP-seq
MIRT2117787	hsa-miR-4498	CLIP-seq
MIRT1392605	hsa-miR-4661-3p	CLIP-seq
MIRT2692049	hsa-miR-4695-5p	CLIP-seq
MIRT1392608	hsa-miR-4711-5p	CLIP-seq
MIRT1392609	hsa-miR-4768-3p	CLIP-seq
MIRT2692050	hsa-miR-4771	CLIP-seq
MIRT1392610	hsa-miR-4796-3p	CLIP-seq
MIRT1392611	hsa-miR-486-3p	CLIP-seq
MIRT2117788	hsa-miR-548an	CLIP-seq
MIRT1392612	hsa-miR-548s	CLIP-seq
MIRT1392614	hsa-miR-645	CLIP-seq
MIRT1392615	hsa-miR-665	CLIP-seq
MIRT2117792	hsa-miR-762	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	18724357
GO:0005783	Component	Endoplasmic reticulum	IBA	21873635
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0006613	Process	Cotranslational protein targeting to membrane	TAS	7789174
GO:0016021	Component	Integral component of membrane	IEA

MIM	HGNC	e!Ensembl
600867	11324	ENSG00000163479

Protein

UniProt ID

P43308

Protein name

Translocon-associated protein subunit beta (TRAP-beta) (Signal sequence receptor subunit beta) (SSR-beta)

Protein function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

PDB

8B6L

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05753	TRAP_beta	3 → 181		Family

Sequence

MRLLSFVVLALFAVTQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELS
DDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPV
VIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKT
KKN

Sequence length

183

Interactions

View interactions

	KEGG
	Protein processing in endoplasmic reticulum

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Hepatocellular	Associate	36003068

SSR2 (signal sequence receptor subunit 2)