SRP72 (signal recognition particle 72)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6731 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Signal recognition particle 72 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SRP72 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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BMFF, BMFS1, HEL103 |
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Chromosome
Chromosome number
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4 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4q12 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SR |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | O76094 | ||||||||||||||||||||
| Protein name | Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein) | ||||||||||||||||||||
| Protein function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:34020957). The SRP complex interacts | ||||||||||||||||||||
| PDB | 5M72 , 5M73 , 5WRV , 5WRW , 7NFX , 8QVW , 8QVX | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 671 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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