Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	6731
Gene name	Signal recognition particle 72
Gene symbol	SRP72
Synonyms (NCBI Gene)	BMFFBMFS1HEL103
Chromosome	4
Chromosome location	4q12
Summary	This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SR

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SNP ID	Visualize variation	Clinical significance	Consequence
rs387907189	G>A	Pathogenic	Coding sequence variant, missense variant, non coding transcript variant
rs587776907	CA>-	Pathogenic	Non coding transcript variant, coding sequence variant, frameshift variant

396

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miRTarBase ID	miRNA	Experiments	Reference
MIRT031562	hsa-miR-16-5p	Proteomics	18668040
MIRT036345	hsa-miR-1229-3p	CLASH	23622248
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509441	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509438	hsa-miR-3924	HITS-CLIP	21572407
MIRT517088	hsa-miR-6083	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509441	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509438	hsa-miR-3924	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT509441	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT509441	hsa-miR-410-3p	PAR-CLIP	20371350
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509438	hsa-miR-3924	PAR-CLIP	20371350
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT517088	hsa-miR-6083	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT517088	hsa-miR-6083	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	22012620
MIRT509441	hsa-miR-410-3p	PAR-CLIP	22012620
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT509438	hsa-miR-3924	PAR-CLIP	22012620
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509441	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517090	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509438	hsa-miR-3924	PAR-CLIP	23446348
MIRT517089	hsa-miR-6516-3p	PAR-CLIP	23446348
MIRT517088	hsa-miR-6083	PAR-CLIP	23446348
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509441	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509438	hsa-miR-3924	PAR-CLIP	23446348
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509441	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509438	hsa-miR-3924	HITS-CLIP	21572407
MIRT517088	hsa-miR-6083	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509441	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509438	hsa-miR-3924	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT509442	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT509441	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT509440	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT509439	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT509441	hsa-miR-410-3p	PAR-CLIP	20371350
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT509438	hsa-miR-3924	PAR-CLIP	20371350
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT517088	hsa-miR-6083	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT517088	hsa-miR-6083	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509441	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT509438	hsa-miR-3924	PAR-CLIP	21572407
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	22012620
MIRT509441	hsa-miR-410-3p	PAR-CLIP	22012620
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT509438	hsa-miR-3924	PAR-CLIP	22012620
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509441	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517090	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509438	hsa-miR-3924	PAR-CLIP	23446348
MIRT517089	hsa-miR-6516-3p	PAR-CLIP	23446348
MIRT517088	hsa-miR-6083	PAR-CLIP	23446348
MIRT509442	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509441	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT509440	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509439	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509438	hsa-miR-3924	PAR-CLIP	23446348
MIRT509437	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT1389242	hsa-miR-103a	CLIP-seq
MIRT1389243	hsa-miR-107	CLIP-seq
MIRT1389244	hsa-miR-1206	CLIP-seq
MIRT1389245	hsa-miR-1254	CLIP-seq
MIRT1389246	hsa-miR-15a	CLIP-seq
MIRT1389247	hsa-miR-15b	CLIP-seq
MIRT1389248	hsa-miR-16	CLIP-seq
MIRT1389249	hsa-miR-195	CLIP-seq
MIRT1389250	hsa-miR-200b	CLIP-seq
MIRT1389251	hsa-miR-200c	CLIP-seq
MIRT1389252	hsa-miR-3065-3p	CLIP-seq
MIRT1389253	hsa-miR-3116	CLIP-seq
MIRT1389254	hsa-miR-3163	CLIP-seq
MIRT1389255	hsa-miR-3185	CLIP-seq
MIRT1389256	hsa-miR-34b	CLIP-seq
MIRT1389257	hsa-miR-3646	CLIP-seq
MIRT1389258	hsa-miR-3662	CLIP-seq
MIRT1389259	hsa-miR-374c	CLIP-seq
MIRT1389260	hsa-miR-3973	CLIP-seq
MIRT1389261	hsa-miR-424	CLIP-seq
MIRT1389262	hsa-miR-429	CLIP-seq
MIRT1389263	hsa-miR-4330	CLIP-seq
MIRT1389264	hsa-miR-4436b-3p	CLIP-seq
MIRT1389265	hsa-miR-4457	CLIP-seq
MIRT1389266	hsa-miR-4477a	CLIP-seq
MIRT1389267	hsa-miR-4501	CLIP-seq
MIRT1389268	hsa-miR-4637	CLIP-seq
MIRT1389269	hsa-miR-4659a-3p	CLIP-seq
MIRT1389270	hsa-miR-4659b-3p	CLIP-seq
MIRT1389271	hsa-miR-4684-5p	CLIP-seq
MIRT1389272	hsa-miR-4709-3p	CLIP-seq
MIRT1389273	hsa-miR-4738-3p	CLIP-seq
MIRT1389274	hsa-miR-4760-5p	CLIP-seq
MIRT1389275	hsa-miR-4762-5p	CLIP-seq
MIRT1389276	hsa-miR-4774-5p	CLIP-seq
MIRT1389277	hsa-miR-4786-3p	CLIP-seq
MIRT1389278	hsa-miR-4797-5p	CLIP-seq
MIRT1389279	hsa-miR-4802-5p	CLIP-seq
MIRT1389280	hsa-miR-497	CLIP-seq
MIRT1389281	hsa-miR-513b	CLIP-seq
MIRT1389282	hsa-miR-514	CLIP-seq
MIRT1389283	hsa-miR-514b-3p	CLIP-seq
MIRT1389284	hsa-miR-548ag	CLIP-seq
MIRT1389285	hsa-miR-548ai	CLIP-seq
MIRT1389286	hsa-miR-548l	CLIP-seq
MIRT1389287	hsa-miR-567	CLIP-seq
MIRT1389288	hsa-miR-577	CLIP-seq
MIRT1389289	hsa-miR-635	CLIP-seq
MIRT1389290	hsa-miR-655	CLIP-seq
MIRT1389291	hsa-miR-661	CLIP-seq
MIRT1389292	hsa-miR-671-5p	CLIP-seq
MIRT1389293	hsa-miR-759	CLIP-seq
MIRT1389294	hsa-miR-765	CLIP-seq
MIRT1389295	hsa-miR-891b	CLIP-seq
MIRT1389296	hsa-miR-942	CLIP-seq
MIRT2116642	hsa-miR-106a	CLIP-seq
MIRT2116643	hsa-miR-106b	CLIP-seq
MIRT1389244	hsa-miR-1206	CLIP-seq
MIRT2116644	hsa-miR-1224-5p	CLIP-seq
MIRT2116645	hsa-miR-1264	CLIP-seq
MIRT2116646	hsa-miR-1304	CLIP-seq
MIRT1389246	hsa-miR-15a	CLIP-seq
MIRT1389247	hsa-miR-15b	CLIP-seq
MIRT1389248	hsa-miR-16	CLIP-seq
MIRT2116647	hsa-miR-17	CLIP-seq
MIRT2116648	hsa-miR-1827	CLIP-seq
MIRT2116649	hsa-miR-1910	CLIP-seq
MIRT1389249	hsa-miR-195	CLIP-seq
MIRT2116650	hsa-miR-2053	CLIP-seq
MIRT2116651	hsa-miR-20a	CLIP-seq
MIRT2116652	hsa-miR-20b	CLIP-seq
MIRT2116653	hsa-miR-2116	CLIP-seq
MIRT2116654	hsa-miR-2682	CLIP-seq
MIRT2116655	hsa-miR-3145-3p	CLIP-seq
MIRT2116656	hsa-miR-3152-3p	CLIP-seq
MIRT2116657	hsa-miR-3161	CLIP-seq
MIRT2116658	hsa-miR-3199	CLIP-seq
MIRT2116659	hsa-miR-3609	CLIP-seq
MIRT2116660	hsa-miR-3617	CLIP-seq
MIRT2116661	hsa-miR-365	CLIP-seq
MIRT2116662	hsa-miR-3915	CLIP-seq
MIRT2116663	hsa-miR-3928	CLIP-seq
MIRT1389261	hsa-miR-424	CLIP-seq
MIRT2116664	hsa-miR-4426	CLIP-seq
MIRT1389264	hsa-miR-4436b-3p	CLIP-seq
MIRT2116665	hsa-miR-4436b-5p	CLIP-seq
MIRT2116666	hsa-miR-4446-5p	CLIP-seq
MIRT1389266	hsa-miR-4477a	CLIP-seq
MIRT2116667	hsa-miR-449c	CLIP-seq
MIRT2116668	hsa-miR-455-3p	CLIP-seq
MIRT2116669	hsa-miR-4643	CLIP-seq
MIRT2116670	hsa-miR-4647	CLIP-seq
MIRT2116671	hsa-miR-4648	CLIP-seq
MIRT2116672	hsa-miR-466	CLIP-seq
MIRT2116673	hsa-miR-4662b	CLIP-seq
MIRT2116674	hsa-miR-4668-3p	CLIP-seq
MIRT2116675	hsa-miR-4677-5p	CLIP-seq
MIRT2116676	hsa-miR-4689	CLIP-seq
MIRT2116677	hsa-miR-4698	CLIP-seq
MIRT2116678	hsa-miR-4699-5p	CLIP-seq
MIRT2116679	hsa-miR-4719	CLIP-seq
MIRT2116680	hsa-miR-4724-3p	CLIP-seq
MIRT2116681	hsa-miR-4755-5p	CLIP-seq
MIRT2116682	hsa-miR-4771	CLIP-seq
MIRT1389277	hsa-miR-4786-3p	CLIP-seq
MIRT2116683	hsa-miR-4789-3p	CLIP-seq
MIRT2116684	hsa-miR-4795-3p	CLIP-seq
MIRT2116685	hsa-miR-4796-3p	CLIP-seq
MIRT1389278	hsa-miR-4797-5p	CLIP-seq
MIRT2116686	hsa-miR-4799-5p	CLIP-seq
MIRT1389280	hsa-miR-497	CLIP-seq
MIRT2116687	hsa-miR-499a-5p	CLIP-seq
MIRT2116688	hsa-miR-519d	CLIP-seq
MIRT2116689	hsa-miR-520d-5p	CLIP-seq
MIRT2116690	hsa-miR-524-5p	CLIP-seq
MIRT2116691	hsa-miR-526b	CLIP-seq
MIRT2116692	hsa-miR-548ah	CLIP-seq
MIRT2116693	hsa-miR-555	CLIP-seq
MIRT1389287	hsa-miR-567	CLIP-seq
MIRT2116694	hsa-miR-622	CLIP-seq
MIRT2116695	hsa-miR-641	CLIP-seq
MIRT1389293	hsa-miR-759	CLIP-seq
MIRT2116696	hsa-miR-93	CLIP-seq
MIRT2116697	hsa-miR-940	CLIP-seq
MIRT2116698	hsa-miR-944	CLIP-seq
MIRT1389242	hsa-miR-103a	CLIP-seq
MIRT1389243	hsa-miR-107	CLIP-seq
MIRT2116644	hsa-miR-1224-5p	CLIP-seq
MIRT2339018	hsa-miR-1244	CLIP-seq
MIRT1389245	hsa-miR-1254	CLIP-seq
MIRT2116645	hsa-miR-1264	CLIP-seq
MIRT2339019	hsa-miR-1273d	CLIP-seq
MIRT2116646	hsa-miR-1304	CLIP-seq
MIRT2339020	hsa-miR-1305	CLIP-seq
MIRT2339021	hsa-miR-141	CLIP-seq
MIRT1389246	hsa-miR-15a	CLIP-seq
MIRT1389247	hsa-miR-15b	CLIP-seq
MIRT1389248	hsa-miR-16	CLIP-seq
MIRT2116648	hsa-miR-1827	CLIP-seq
MIRT2116649	hsa-miR-1910	CLIP-seq
MIRT1389249	hsa-miR-195	CLIP-seq
MIRT2339022	hsa-miR-200a	CLIP-seq
MIRT1389250	hsa-miR-200b	CLIP-seq
MIRT1389251	hsa-miR-200c	CLIP-seq
MIRT2116650	hsa-miR-2053	CLIP-seq
MIRT2339023	hsa-miR-218	CLIP-seq
MIRT2116654	hsa-miR-2682	CLIP-seq
MIRT1389252	hsa-miR-3065-3p	CLIP-seq
MIRT1389253	hsa-miR-3116	CLIP-seq
MIRT2339024	hsa-miR-3120-5p	CLIP-seq
MIRT2339025	hsa-miR-3134	CLIP-seq
MIRT2116655	hsa-miR-3145-3p	CLIP-seq
MIRT1389254	hsa-miR-3163	CLIP-seq
MIRT2339026	hsa-miR-3168	CLIP-seq
MIRT1389255	hsa-miR-3185	CLIP-seq
MIRT2339027	hsa-miR-3187-3p	CLIP-seq
MIRT2339028	hsa-miR-335	CLIP-seq
MIRT2339029	hsa-miR-342-3p	CLIP-seq
MIRT1389256	hsa-miR-34b	CLIP-seq
MIRT2339030	hsa-miR-3591-5p	CLIP-seq
MIRT2339031	hsa-miR-3606	CLIP-seq
MIRT2339032	hsa-miR-3607-5p	CLIP-seq
MIRT2116660	hsa-miR-3617	CLIP-seq
MIRT1389257	hsa-miR-3646	CLIP-seq
MIRT2339033	hsa-miR-3647-3p	CLIP-seq
MIRT2116661	hsa-miR-365	CLIP-seq
MIRT2339034	hsa-miR-3653	CLIP-seq
MIRT2339035	hsa-miR-3658	CLIP-seq
MIRT1389258	hsa-miR-3662	CLIP-seq
MIRT1389259	hsa-miR-374c	CLIP-seq
MIRT2116662	hsa-miR-3915	CLIP-seq
MIRT2339036	hsa-miR-3926	CLIP-seq
MIRT2116663	hsa-miR-3928	CLIP-seq
MIRT1389261	hsa-miR-424	CLIP-seq
MIRT2339037	hsa-miR-4267	CLIP-seq
MIRT2339038	hsa-miR-4282	CLIP-seq
MIRT1389262	hsa-miR-429	CLIP-seq
MIRT2339039	hsa-miR-4302	CLIP-seq
MIRT1389263	hsa-miR-4330	CLIP-seq
MIRT2116664	hsa-miR-4426	CLIP-seq
MIRT2339040	hsa-miR-4428	CLIP-seq
MIRT2116665	hsa-miR-4436b-5p	CLIP-seq
MIRT2116666	hsa-miR-4446-5p	CLIP-seq
MIRT2339041	hsa-miR-4474-3p	CLIP-seq
MIRT1389266	hsa-miR-4477a	CLIP-seq
MIRT2339042	hsa-miR-4494	CLIP-seq
MIRT2116667	hsa-miR-449c	CLIP-seq
MIRT1389267	hsa-miR-4501	CLIP-seq
MIRT2339043	hsa-miR-4529-5p	CLIP-seq
MIRT2339044	hsa-miR-4534	CLIP-seq
MIRT2116668	hsa-miR-455-3p	CLIP-seq
MIRT2339045	hsa-miR-4640-5p	CLIP-seq
MIRT2116670	hsa-miR-4647	CLIP-seq
MIRT1389269	hsa-miR-4659a-3p	CLIP-seq
MIRT1389270	hsa-miR-4659b-3p	CLIP-seq
MIRT2116673	hsa-miR-4662b	CLIP-seq
MIRT2116674	hsa-miR-4668-3p	CLIP-seq
MIRT1389271	hsa-miR-4684-5p	CLIP-seq
MIRT2116676	hsa-miR-4689	CLIP-seq
MIRT2116677	hsa-miR-4698	CLIP-seq
MIRT2339046	hsa-miR-4717-3p	CLIP-seq
MIRT2339047	hsa-miR-4717-5p	CLIP-seq
MIRT2116679	hsa-miR-4719	CLIP-seq
MIRT2339048	hsa-miR-4726-5p	CLIP-seq
MIRT2116681	hsa-miR-4755-5p	CLIP-seq
MIRT1389274	hsa-miR-4760-5p	CLIP-seq
MIRT1389275	hsa-miR-4762-5p	CLIP-seq
MIRT2116682	hsa-miR-4771	CLIP-seq
MIRT1389276	hsa-miR-4774-5p	CLIP-seq
MIRT1389278	hsa-miR-4797-5p	CLIP-seq
MIRT2116686	hsa-miR-4799-5p	CLIP-seq
MIRT1389279	hsa-miR-4802-5p	CLIP-seq
MIRT2339049	hsa-miR-493	CLIP-seq
MIRT2339050	hsa-miR-496	CLIP-seq
MIRT1389280	hsa-miR-497	CLIP-seq
MIRT2116687	hsa-miR-499a-5p	CLIP-seq
MIRT2339051	hsa-miR-508-5p	CLIP-seq
MIRT2116689	hsa-miR-520d-5p	CLIP-seq
MIRT2116690	hsa-miR-524-5p	CLIP-seq
MIRT1389284	hsa-miR-548ag	CLIP-seq
MIRT1389285	hsa-miR-548ai	CLIP-seq
MIRT2339052	hsa-miR-548m	CLIP-seq
MIRT2116693	hsa-miR-555	CLIP-seq
MIRT1389288	hsa-miR-577	CLIP-seq
MIRT2339053	hsa-miR-578	CLIP-seq
MIRT2339054	hsa-miR-581	CLIP-seq
MIRT2339055	hsa-miR-600	CLIP-seq
MIRT2116694	hsa-miR-622	CLIP-seq
MIRT1389289	hsa-miR-635	CLIP-seq
MIRT2339056	hsa-miR-636	CLIP-seq
MIRT2116695	hsa-miR-641	CLIP-seq
MIRT2339057	hsa-miR-642a	CLIP-seq
MIRT2339058	hsa-miR-654-3p	CLIP-seq
MIRT1389290	hsa-miR-655	CLIP-seq
MIRT1389291	hsa-miR-661	CLIP-seq
MIRT2339059	hsa-miR-663b	CLIP-seq
MIRT1389293	hsa-miR-759	CLIP-seq
MIRT2339060	hsa-miR-766	CLIP-seq
MIRT1389295	hsa-miR-891b	CLIP-seq
MIRT2339061	hsa-miR-921	CLIP-seq
MIRT2116697	hsa-miR-940	CLIP-seq
MIRT1389296	hsa-miR-942	CLIP-seq
MIRT2116698	hsa-miR-944	CLIP-seq
MIRT1389246	hsa-miR-15a	CLIP-seq
MIRT1389247	hsa-miR-15b	CLIP-seq
MIRT1389248	hsa-miR-16	CLIP-seq
MIRT1389249	hsa-miR-195	CLIP-seq
MIRT1389261	hsa-miR-424	CLIP-seq
MIRT1389266	hsa-miR-4477a	CLIP-seq
MIRT1389280	hsa-miR-497	CLIP-seq
MIRT2433541	hsa-miR-3125	CLIP-seq
MIRT2433542	hsa-miR-3916	CLIP-seq
MIRT2433543	hsa-miR-583	CLIP-seq
MIRT2339019	hsa-miR-1273d	CLIP-seq
MIRT2339021	hsa-miR-141	CLIP-seq
MIRT2632740	hsa-miR-193a-5p	CLIP-seq
MIRT2339022	hsa-miR-200a	CLIP-seq
MIRT2339032	hsa-miR-3607-5p	CLIP-seq
MIRT1389267	hsa-miR-4501	CLIP-seq
MIRT2116668	hsa-miR-455-3p	CLIP-seq
MIRT2339019	hsa-miR-1273d	CLIP-seq
MIRT2339032	hsa-miR-3607-5p	CLIP-seq
MIRT1389267	hsa-miR-4501	CLIP-seq
MIRT2116668	hsa-miR-455-3p	CLIP-seq

Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005047	Function	Signal recognition particle binding	IPI	17254600
GO:0005515	Function	Protein binding	IPI	16672232, 24965446, 32296183, 33961781, 35271311
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	22541560
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IBA
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IDA	18089836
GO:0005786	Component	Signal recognition particle, endoplasmic reticulum targeting	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	IBA
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	IEA
GO:0008312	Function	7S RNA binding	IBA
GO:0008312	Function	7S RNA binding	IEA
GO:0008312	Function	7S RNA binding	IMP	27899666
GO:0030911	Function	TPR domain binding	IPI	27899666
GO:0043022	Function	Ribosome binding	IBA
GO:0043022	Function	Ribosome binding	IMP	27899666
GO:0048500	Component	Signal recognition particle	IDA	27899666
GO:0048500	Component	Signal recognition particle	IEA
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
602122	11303	ENSG00000174780

O76094

Protein name

Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein)

Protein function

Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:34020957). The SRP complex interacts

PDB

5M72 , 5M73 , 5WRV , 5WRW , 7NFX , 8QVW , 8QVX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF17004	SRP_TPR_like	30 → 157	Putative TPR-like repeat	Repeat
PF13181	TPR_8	176 → 208	Tetratricopeptide repeat	Repeat
PF08492	SRP72	531 → 588	SRP72 RNA-binding domain	Domain

Sequence

MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGS
FKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLY
RLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY
NTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQG
RTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSK
KQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIEL
LQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEE
DIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKD
IHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGD
SQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGK
GTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQ
QKKKKGGKGGW

Sequence length

671

Interactions

View interactions

	KEGG		Reactome
	Protein export		SRP-dependent cotranslational protein targeting to membrane

166

Show/Hide Unknown Diseases (18)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs76774105	RCV005921564
Autosomal dominant aplasia and myelodysplasia	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs116799047, rs572275305, rs11610, rs7700034, rs375436807, rs369761160, rs763130641, rs377395395, rs192401229, rs771569541, rs760548618, rs12513091, rs763655714, rs886059498, rs541665813 View all (69 more)	RCV005232381 RCV005232383 RCV001810120 RCV001810150 RCV002506848 RCV002492057 RCV005055191 RCV002466798 RCV000310610 RCV003337780 RCV005036797 RCV000364512 RCV000279818 RCV000315753 RCV000288069 RCV000353198 RCV000370673 RCV000330791 RCV000382011 RCV000342768 RCV005602062 RCV000266588 RCV000321084 RCV000378058 RCV000391409 RCV000263972 RCV000355312 RCV000372740 RCV000295395 RCV000386129 RCV000346644 RCV000345332 RCV000340523 RCV000260891 RCV000313798 RCV000273854 RCV000285487 RCV000376371 RCV000312195 RCV000272329 RCV000391775 RCV000319836 RCV000325091 RCV000363461 RCV000281124 RCV000372097 RCV000363241 RCV000293187 RCV000350488 RCV000304944 RCV000361991 RCV000333970 RCV000294141 RCV000305756 RCV000393078 RCV000272257 RCV000401507 RCV000321410 RCV000262862 RCV000396841 RCV000398602 RCV000300710 RCV000382993 RCV000325037 RCV005628165 RCV004573675 RCV001151985 RCV000024352 RCV000024353 RCV005034045 RCV005628146 RCV001151984 RCV001153246 RCV001155843 RCV001155845 RCV001157548 RCV001152087 RCV001152088 RCV001153351 RCV001153352 RCV001155963 RCV001155964 RCV001155965 RCV001157665 RCV001157666 RCV001157667 RCV001157668 RCV001153247
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign	rs76774105, rs17086898	RCV005921573 RCV005924710
Colon adenocarcinoma	Uncertain significance	rs2545754987	RCV005927102
Familial cancer of breast	Benign; Conflicting classifications of pathogenicity	rs201153427, rs4340842, rs186908289	RCV005915892 RCV005925156 RCV005913930
Familial pancreatic carcinoma	Benign	rs17086898	RCV005924707
Hepatocellular carcinoma	Benign	rs76774105, rs17086898	RCV005921565 RCV005924705
Lung cancer	Benign	rs76774105	RCV005921571
Lymphoma	Benign; Likely benign	rs17086898, rs779867478	RCV005924708 RCV005930473
Malignant lymphoma, large B-cell, diffuse	Benign	rs76774105	RCV005921568
Nonpapillary renal cell carcinoma	Benign	rs76774105, rs17086898	RCV005921566 RCV005924706
Ovarian cancer	Benign	rs76774105	RCV005921567
Ovarian serous cystadenocarcinoma	Uncertain significance	rs2110113831	RCV005924191
Sarcoma	Benign	rs76774105	RCV005921569
SRP72-related disorder	Conflicting classifications of pathogenicity; Likely benign; Uncertain significance; Benign	rs201095666, rs201570324, rs201102960, rs771523590, rs369761160, rs773723388, rs182243599, rs755620294, rs768252482, rs138988524, rs936610987, rs763130641, rs377395395, rs907758417, rs139502866 View all (26 more)	RCV003928863 RCV003976224 RCV003913408 RCV004749746 RCV004749803 RCV003401998 RCV003893022 RCV003911062 RCV003978864 RCV003970990 RCV003978794 RCV003408227 RCV003973410 RCV003973553 RCV003418671 RCV003410047 RCV003410284 RCV003391671 RCV003400399 RCV003414208 RCV004725183 RCV003409552 RCV003901235 RCV003972472 RCV003912479 RCV003957806 RCV003970008 RCV003970009 RCV003901294 RCV003893419 RCV004750442 RCV003893459 RCV003893722 RCV003902109 RCV003899079 RCV003897189 RCV003957008 RCV003952326 RCV003944648 RCV003959443 RCV004748792
Thymoma	Benign	rs76774105	RCV005921570
Uterine carcinosarcoma	Benign	rs17086898, rs12513091	RCV005924709 RCV005897850
Uterine corpus endometrial carcinoma	Benign	rs76774105	RCV005921572

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Absent patella	Associate	22541560
Anemia Aplastic	Associate	22541560
GATA2 Deficiency	Associate	26693794
Leukemia Myeloid Acute	Associate	26693794
Neural Tube Defects	Associate	22541560

SRP72 (signal recognition particle 72)