| Disease Name |
Relationship Type |
References |
| 3 Hydroxy 3 Methylglutaryl CoA Lyase Deficiency |
Associate |
28377796 |
| Abortion Habitual |
Inhibit |
26821085 |
| Abortion Spontaneous |
Associate |
25140979 |
| Achalasia Addisonianism Alacrimia syndrome |
Associate |
34777635 |
| Acromegaly |
Associate |
29046499 |
| Acute Kidney Injury |
Associate |
26787049 |
| Adenocarcinoma |
Associate |
15534883, 20638682 |
| Adenocarcinoma of Lung |
Inhibit |
20690800 |
| Adenocarcinoma of Lung |
Associate |
23271813 |
| Adenoma |
Associate |
10363564 |
| AIDS related Kaposi sarcoma |
Associate |
14656937 |
| Alcoholism |
Associate |
26937962 |
| Alzheimer Disease |
Associate |
17376152, 25542503, 26696693, 26881032, 32711556, 32925069, 34857756, 7856748 |
| Amyloidosis |
Associate |
32711556 |
| Amyotrophic Lateral Sclerosis |
Associate |
35627142 |
| Anemia Sickle Cell |
Associate |
21574139, 34958669, 35274104 |
| Angina Pectoris |
Associate |
20206073 |
| Aortic Aneurysm Abdominal |
Associate |
34777635 |
| Arthritis Psoriatic |
Associate |
15266664 |
| Arthritis Reactive |
Associate |
32934294 |
| Arthritis Rheumatoid |
Associate |
19242068, 22006448, 9122163 |
| Asbestosis |
Associate |
19636420, 23984360 |
| Asthma |
Associate |
15743779, 18048809, 22610343, 25931357, 28208751 |
| Asthma Exercise Induced |
Associate |
22610343 |
| Astrocytoma |
Associate |
12744469 |
| Ataxia Telangiectasia |
Associate |
25882094 |
| Atherosclerosis |
Associate |
8644718 |
| Atrial Fibrillation |
Associate |
33747117 |
| Attention Deficit Disorder with Hyperactivity |
Associate |
23588476 |
| Atypical Squamous Cells of the Cervix |
Associate |
21725155 |
| Autism Spectrum Disorder |
Associate |
23333625 |
| Autism Spectrum Disorder |
Inhibit |
31018497, 37673435 |
| Bacterial Infections |
Associate |
29113587 |
| Balkan Nephropathy |
Associate |
31382611 |
| Barrett Esophagus |
Associate |
15884106 |
| Behcet Syndrome |
Inhibit |
39317938 |
| Bicuspid Aortic Valve Disease |
Associate |
28185644 |
| Bipolar Disorder |
Associate |
23785434, 34387669, 36476443 |
| Blood Coagulation Disorders |
Associate |
35361071 |
| Bone Diseases |
Associate |
22740707 |
| Brain Neoplasms |
Associate |
18682580, 35796015, 8980385 |
| Breast Diseases |
Associate |
26678158 |
| Breast Neoplasms |
Associate |
11929863, 15217492, 15535847, 15883815, 16080463, 16571274, 16684880, 16859522, 16945136, 18553161, 18845242, 19339246, 19509150, 19563893, 20309628, 21527182, 22982566, 23429290, 23875900, 23886214, 25651975, 26678158, 26707081, 26957268, 27400860, 28587495, 28925482, 30486606, 30932749, 31311202, 32920119, 35301432, 36077241, 38375721, 9582369 View all (20 more) |
| Breast Neoplasms |
Inhibit |
17965603, 24448804 |
| Breast Neoplasms |
Stimulate |
28368421 |
| Breast Neoplasms Male |
Associate |
18553161 |
| Calcinosis Cutis |
Associate |
29914010, 33092599 |
| Carcinogenesis |
Associate |
10363564, 1306294, 15883815, 18827816, 20233853, 21725155, 37660159 |
| Carcinoma Adenoid Cystic |
Associate |
26847304, 27181103 |
| Carcinoma Basal Cell |
Associate |
27057281 |
| Carcinoma Ductal |
Associate |
21527182 |
| Carcinoma Hepatocellular |
Associate |
25894370, 27158203, 27221200 |
| Carcinoma Intraductal Noninfiltrating |
Associate |
21527182 |
| Carcinoma Non Small Cell Lung |
Associate |
15534883, 20873987, 31553952, 35188072 |
| Carcinoma Ovarian Epithelial |
Associate |
28884887 |
| Carcinoma Renal Cell |
Associate |
25315187, 25755722, 27157976, 28165386, 29914010, 33092599, 33953831, 34528699 |
| Carcinoma Squamous Cell |
Associate |
15298726, 28099906, 30896828 |
| Carcinoma Squamous Cell |
Inhibit |
20690800 |
| Cardiomyopathies |
Associate |
15591282, 35274104, 37872948 |
| Cardiomyopathy Dilated |
Associate |
33303703 |
| Cardiomyopathy Restrictive |
Inhibit |
31037987 |
| Cardiovascular Diseases |
Associate |
17331249, 36012132 |
| Cartilage Diseases |
Associate |
29339024 |
| Cataract |
Inhibit |
23970468 |
| Cataract |
Associate |
8755643 |
| Cerebrovascular Disorders |
Associate |
34958669 |
| Cerebrovascular Trauma |
Associate |
34790286 |
| Chemical and Drug Induced Liver Injury |
Associate |
34887513 |
| Chemical and Drug Induced Liver Injury |
Inhibit |
36411702 |
| Cholangitis Sclerosing |
Associate |
29180269 |
| Chorioamnionitis |
Associate |
19900038 |
| Chronic Periodontitis |
Associate |
21975116 |
| Cockayne Syndrome |
Associate |
30009828 |
| Cognition Disorders |
Associate |
23588476, 34857756 |
| Cognitive Dysfunction |
Associate |
26696693, 26881032 |
| Colitis Ulcerative |
Associate |
24483941, 39510220 |
| Colorectal Neoplasms |
Associate |
10363564, 10970696, 16107721, 26674755, 26846100, 33666342, 35883447, 36299603 |
| Congenital disorder of glycosylation type II |
Inhibit |
29453449 |
| Congenital Hereditary and Neonatal Diseases and Abnormalities |
Associate |
9886257 |
| Conotruncal cardiac defects |
Associate |
24585533 |
| Corneal dystrophy Avellino type |
Stimulate |
19497990 |
| Corneal Endothelial Cell Loss |
Associate |
21854648 |
| Coronary Artery Disease |
Associate |
20009389, 22738689, 30225256 |
| Coronary Disease |
Associate |
27067415 |
| COVID 19 |
Associate |
36493512 |
| Cowden Like Syndrome |
Associate |
18678321 |
| Crohn Disease |
Associate |
28052094, 33882797 |
| Cystic Fibrosis |
Associate |
21931865 |
| Death |
Associate |
20309628, 24811984 |
| Dental Caries |
Associate |
40142243 |
| Depressive Disorder |
Associate |
23725507, 23785434, 25295643 |
| Depressive Disorder Major |
Associate |
23725507 |
| Dermatitis Atopic 1 |
Associate |
15128298 |
| Diabetes Gestational |
Associate |
34190178 |
| Diabetes Mellitus |
Associate |
16475114, 18423055, 20097730, 22688013, 26881045, 27411103, 30037352, 36010644 |
| Diabetes Mellitus |
Stimulate |
21975116, 24732311 |
| Diabetes Mellitus |
Inhibit |
37698290 |
| Diabetes Mellitus Type 1 |
Associate |
19752172, 24732311, 24819633 |
| Diabetes Mellitus Type 2 |
Associate |
18057537, 22740707, 27258818, 30803440, 32925069, 33426802, 33761612, 37698290 |
| Diabetes Mellitus Type 2 |
Stimulate |
23685312 |
| Diabetic Angiopathies |
Associate |
30217947 |
| Diabetic Nephropathies |
Associate |
24819633, 37698290 |
| Diabetic Retinopathy |
Associate |
18057537, 19752172 |
| Down Syndrome |
Associate |
7856748 |
| Drug Related Side Effects and Adverse Reactions |
Associate |
12826016, 20309628, 22982566, 8353281 |
| Drug Related Side Effects and Adverse Reactions |
Inhibit |
17394531 |
| Drug Resistant Epilepsy |
Associate |
28222320 |
| Dupuytren Contracture |
Associate |
34270583 |
| Dyskeratosis Congenita |
Associate |
29055871 |
| Dyslipidemias |
Associate |
28315561, 36759651 |
| Edema |
Stimulate |
27487831 |
| Endometrial Neoplasms |
Associate |
29673664, 31795319 |
| Epilepsy |
Associate |
32219137 |
| Erysipelas |
Associate |
28512644 |
| Esophageal Neoplasms |
Associate |
22994704, 25659582 |
| Esophageal Squamous Cell Carcinoma |
Associate |
15986332, 21517111 |
| Essential Hypertension |
Associate |
21053180 |
| Exfoliation Syndrome |
Stimulate |
23805041 |
| Exocrine Pancreatic Insufficiency |
Associate |
17548864 |
| Fabry Disease |
Associate |
27938475 |
| Fatigue Syndrome Chronic |
Associate |
24054763 |
| Fever |
Associate |
10970696 |
| Fibrosarcoma |
Associate |
8702551 |
| Fibrosis |
Associate |
33924242 |
| Fluorosis Dental |
Associate |
35766568 |
| Friedreich Ataxia |
Associate |
11734214, 21687738 |
| Genetic Diseases Inborn |
Associate |
8633092 |
| Geographic Atrophy |
Associate |
24667176 |
| Gingival Pocket |
Associate |
31470840 |
| Glioblastoma |
Associate |
11207049, 21649900, 36838582 |
| Glioma |
Associate |
23259684, 28567457, 36809279 |
| Glomerulonephritis Membranous |
Associate |
20150532 |
| Glucose Intolerance |
Associate |
27411103 |
| Graves Ophthalmopathy |
Associate |
22065933 |
| Growth Disorders |
Associate |
16107721 |
| HAIR AN syndrome |
Stimulate |
16470310 |
| Hamartoma Syndrome Multiple |
Associate |
18678321 |
| Head and Neck Neoplasms |
Associate |
34479919, 34681918, 37108069 |
| Hearing Disorders |
Associate |
26400460 |
| Hearing Loss |
Associate |
20534900, 22877234, 25484013, 26400460 |
| Hearing Loss Noise Induced |
Associate |
20534900, 25484013 |
| Hearing Loss Sensorineural |
Associate |
38098073 |
| Heart Defects Congenital |
Associate |
24811984 |
| Heart Diseases |
Associate |
23904881 |
| Hemolysis |
Associate |
35274104 |
| Hepatitis C |
Associate |
23857333 |
| Hepatitis C |
Stimulate |
9626579 |
| Hepatitis C Chronic |
Associate |
9626579 |
| Hepatolenticular Degeneration |
Associate |
19571474 |
| Hereditary Breast and Ovarian Cancer Syndrome |
Associate |
15883815 |
| HIV Infections |
Associate |
2034677 |
| Huntington Disease |
Associate |
30120672 |
| Hyperglycemia |
Inhibit |
24093550 |
| Hyperlipidemia Familial Combined |
Associate |
9683614 |
| Hyperoxia |
Associate |
15286004 |
| Hypertension |
Associate |
17331249 |
| Hypothyroidism |
Associate |
30736780 |
| Hypoxia |
Associate |
20110409, 35301432 |
| Hypoxia |
Stimulate |
23958427, 24267255 |
| Hypoxia |
Inhibit |
24275138, 30137220, 33174051 |
| Idiopathic Pulmonary Fibrosis |
Inhibit |
31119153 |
| Idiopathic Pulmonary Fibrosis |
Associate |
40294812 |
| Immunoglobulin G4 Related Disease |
Associate |
35718799 |
| Infections |
Stimulate |
15337840, 20538313, 31849956 |
| Infertility Female |
Associate |
28040123 |
| Infertility Male |
Associate |
36592993 |
| Inflammation |
Associate |
18205184, 18396798, 22272346, 22688013, 24483941, 32467324, 35361071, 36010644, 36012132 |
| Inflammation |
Inhibit |
19900038 |
| Inflammatory Bowel Diseases |
Stimulate |
29180269 |
| Inflammatory Bowel Diseases |
Associate |
32410873, 9122163 |
| Inflammatory Breast Neoplasms |
Associate |
18248671, 21559822 |
| Insomnia Fatal Familial |
Associate |
27338255 |
| Intellectual Disability |
Associate |
25372290 |
| Intervertebral Disc Degeneration |
Associate |
35409356 |
| Iron Overload |
Associate |
15591282 |
| Ischemic Stroke |
Associate |
34790286 |
| Keratoconus |
Associate |
31576926 |
| Kidney Diseases |
Associate |
24819633 |
| Kidney Failure Chronic |
Associate |
26881045, 31340563, 31382611 |
| Kidney Failure Chronic |
Inhibit |
26881045 |
| Kidney Neoplasms |
Associate |
28165386 |
| Labor Pain |
Associate |
19900038 |
| Lactic Acidosis Fatal Infantile |
Stimulate |
8755643 |
| Leigh Disease |
Associate |
29453449 |
| Leukemia |
Associate |
17496311, 8353281 |
| Leukemia Lymphocytic Chronic B Cell |
Associate |
34001853 |
| Leukemia Myelogenous Chronic BCR ABL Positive |
Associate |
40565143 |
| Leukemia Myeloid |
Associate |
8353281 |
| Leukemia Myeloid Acute |
Associate |
10759716 |
| Leukoencephalopathies |
Associate |
36430258 |
| Leukoplakia Oral |
Associate |
32378537 |
| Lichen Planus Oral |
Associate |
32378537 |
| Liver Diseases Alcoholic |
Associate |
26937962 |
| Lung Neoplasms |
Associate |
18466086, 20690800, 21705328, 23271813, 30111255, 31205586, 33846781, 36037114, 38013118, 40294812 |
| Lymphatic Metastasis |
Associate |
18460737, 20618948, 21319141, 22517484, 40244057 |
| Lymphatic Metastasis |
Stimulate |
24569473 |
| Lymphoma Large B Cell Diffuse |
Associate |
27737889 |
| Macular Degeneration |
Associate |
19753309, 24497574, 24667176, 27998274 |
| Malformations of Cortical Development |
Associate |
25295643 |
| Medulloblastoma |
Associate |
26400460 |
| Melanoma |
Associate |
29342889, 8144583, 8464931 |
| Melanoma |
Inhibit |
29342889 |
| Melanoma Cutaneous Malignant |
Associate |
36631465, 37401304 |
| Melanosis |
Stimulate |
35840442 |
| MELAS Syndrome |
Associate |
34106788 |
| Meningomyelocele |
Associate |
22972774, 23792044 |
| Mental Disorders |
Associate |
23785434, 40725019 |
| Mesothelioma |
Associate |
10737384 |
| Mesothelioma Malignant |
Associate |
10737384, 38013118 |
| Metabolic Diseases |
Associate |
26881045 |
| Metabolic Syndrome |
Associate |
22272346 |
| Migraine Disorders |
Associate |
25295643 |
| Migraine with Aura |
Associate |
25295643 |
| Mitochondrial complex I deficiency |
Associate |
8755643 |
| Mitochondrial Diseases |
Associate |
17192393, 18678321, 23138846, 28652419, 36737723 |
| Mitochondrial Diseases |
Stimulate |
21175348 |
| Mitochondrial Diseases |
Inhibit |
34958669 |
| Mitochondrial Myopathies |
Associate |
17551003 |
| Mood Disorders |
Associate |
23725507 |
| Multiple Chemical Sensitivity |
Associate |
23967348 |
| Multiple Myeloma |
Associate |
15908783, 22471522, 23063726 |
| Multiple Sclerosis |
Associate |
35732787 |
| Muscle Weakness |
Associate |
28025995 |
| Muscular Diseases |
Associate |
28025995 |
| Muscular Dystrophy Duchenne |
Stimulate |
21773993 |
| Mycoses |
Associate |
31856463 |
| Myocardial Ischemia |
Associate |
28165386 |
| Myofibrillar Myopathy |
Associate |
17784878 |
| Myopathy with Lactic Acidosis Hereditary |
Stimulate |
23754354 |
| Myostatin related muscle hypertrophy |
Stimulate |
27088469 |
| Myotilinopathy |
Associate |
17784878 |
| Myotonic Dystrophy |
Associate |
21975116 |
| Nasopharyngeal Carcinoma |
Associate |
22160175, 36737723 |
| Necrosis |
Associate |
12744469 |
| Neoplasm Metastasis |
Stimulate |
10363564, 26359457, 27181103 |
| Neoplasm Metastasis |
Associate |
18460737, 19563893, 20618948, 22580338, 23217164, 23429290, 30536754 |
| Neoplasms |
Stimulate |
10363564, 35001007 |
| Neoplasms |
Associate |
10970696, 15598343, 15908783, 15986332, 16859522, 18173856, 18280257, 18553161, 18571701, 18594523, 18784358, 18840609, 19014992, 19074833, 19563893, 20309628, 20690800, 21527182, 21804600, 21940907, 22517484, 23271813, 23429290, 23456297, 23632049, 23873331, 23886214, 24047462, 24411622, 25651975, 26674755, 26846100, 26881045, 28165386, 28884887, 29914010, 30030980, 30042310, 30111255, 30536754, 30896828, 32863233, 33092599, 33666342, 34285315, 34681918, 35188072, 37108069, 37660159 View all (34 more) |
| Neoplasms |
Inhibit |
11278550, 11853549, 14656937, 15883815, 16107721, 16999822, 22994704, 27221200, 29596499, 30570876, 35017469, 8980385 |
| Neoplasms Neuroepithelial |
Associate |
11207049 |
| Neoplastic Syndromes Hereditary |
Associate |
15591282 |
| Nerve Degeneration |
Inhibit |
12067230, 17394531 |
| Nerve Degeneration |
Associate |
33149812 |
| Neural Tube Defects |
Associate |
34090432 |
| Neuroblastoma |
Associate |
18280257 |
| Neurodegenerative Diseases |
Associate |
23785434 |
| Neurologic Manifestations |
Associate |
25295643 |
| Neuroma Acoustic |
Associate |
18682580 |
| Neurotoxicity Syndromes |
Associate |
24462953 |
| Neutropenia |
Associate |
20309628 |
| Neutrophil Immunodeficiency Syndrome |
Associate |
33666342 |
| Niemann Pick Disease Type C |
Associate |
23217164 |
| Non alcoholic Fatty Liver Disease |
Associate |
21727734, 33555168 |
| Obesity |
Associate |
21727734, 22688013, 23685312, 26123268, 32709094, 33761612, 35968712, 38127891 |
| Obstetric Labor Premature |
Associate |
19900038 |
| Optic Atrophy Hereditary Leber |
Associate |
15720387 |
| Oral Submucous Fibrosis |
Associate |
32378537 |
| Oropharyngeal Neoplasms |
Associate |
40244057 |
| Osteoarthritis |
Associate |
18784066, 23138846, 29339024, 38127891 |
| Osteoarthritis |
Stimulate |
22108257 |
| Osteogenesis Imperfecta |
Associate |
32141579 |
| Osteoglophonic dwarfism |
Associate |
33149812 |
| Osteoporosis |
Associate |
18924182, 21773993, 23329517 |
| Ovarian Neoplasms |
Associate |
1306294, 18594523, 26359457, 30700285, 35594792 |
| Pancreatic Neoplasms |
Associate |
15155719, 18205184, 18497575, 19351855, 20097730, 22547077, 28099906 |
| Pancreatic Neoplasms |
Stimulate |
20097730 |
| Parkinson Disease |
Associate |
22723845, 23785434, 28922168, 31601079 |
| Parkinson Disease |
Stimulate |
25279756, 31601079 |
| Parkinsonian Disorders |
Associate |
9042918 |
| Paroxysmal ventricular fibrillation |
Associate |
21130430 |
| Periodontal Diseases |
Associate |
31470840 |
| Periodontitis |
Associate |
21975116, 40294979 |
| Peritonitis |
Associate |
24204994 |
| Personality Disorders |
Associate |
18784358, 36676755 |
| Pneumonia |
Associate |
35774277 |
| Polycystic Ovary Syndrome |
Associate |
32289280 |
| Polycythemia Vera |
Associate |
30570876 |
| Post Acute COVID 19 Syndrome |
Associate |
37373377 |
| Postoperative Nausea and Vomiting |
Associate |
30813952 |
| Precancerous Conditions |
Associate |
15986332, 20872977 |
| Preterm Premature Rupture of the Membranes |
Associate |
19900038 |
| Primary Myelofibrosis |
Associate |
30259659 |
| Progeroid syndrome neonatal |
Associate |
24799429 |
| Prostate Cancer Hereditary 7 |
Associate |
17465268, 19074884, 19528373, 20477822 |
| Prostatic Neoplasms |
Associate |
15781667, 16261162, 17465268, 17876045, 18296681, 18553161, 18571701, 18784358, 19074884, 19368118, 19528373, 20477822, 21982398, 22564066, 23315858, 24269899, 24437375, 24711484, 25662905, 26147925, 27197287, 27325180, 28069826, 29684818, 31929112, 36295574 View all (11 more) |
| Prostatitis |
Associate |
19368118 |
| Pterygium |
Associate |
34826419 |
| Pulmonary Arterial Hypertension |
Associate |
28272301 |
| Pulmonary Disease Chronic Obstructive |
Stimulate |
15516670 |
| Pulmonary Disease Chronic Obstructive |
Associate |
17567676, 19213780, 28025995, 34831227, 35609226 |
| Radiation Injuries |
Stimulate |
36737723 |
| Radiation Pneumonitis |
Associate |
22144047 |
| Renal Insufficiency Chronic |
Associate |
26881045, 27630759, 31924810 |
| Respiratory Distress Syndrome |
Associate |
31340563 |
| Retinal Dysplasia |
Associate |
20233853 |
| Ring Chromosome 20 Syndrome |
Associate |
33149812 |
| Rotavirus Infections |
Stimulate |
20538313 |
| Sarcoma Ewing |
Associate |
15581626 |
| Sarcoma Kaposi |
Associate |
18987137 |
| Schizophrenia |
Associate |
23588476, 23785434 |
| Scleroderma Systemic |
Inhibit |
31119153 |
| Seizures |
Associate |
32219137 |
| Severe Acute Respiratory Syndrome |
Associate |
40142243 |
| Single Umbilical Artery |
Associate |
30225256 |
| Skin Neoplasms |
Associate |
9886257 |
| Small Cell Lung Carcinoma |
Associate |
25400754 |
| Smoke Inhalation Injury |
Stimulate |
28841898, 37108069 |
| Squamous Cell Carcinoma of Head and Neck |
Associate |
18460737, 19487542, 20618948, 21940907, 22580338, 28841898, 28904321, 29802697, 34479919 |
| Squamous Intraepithelial Lesions |
Associate |
21725155 |
| Status Asthmaticus |
Associate |
15743779 |
| Stomach Diseases |
Associate |
20233853, 30574618 |
| Stomach Neoplasms |
Associate |
14503839, 18384434, 18827816, 20233853, 20872977, 21725155, 22517484, 25545243, 25684475, 26646027, 30242560, 30536754 |
| Stomach Ulcer |
Associate |
20872977 |
| Tardive Dyskinesia |
Associate |
22615781 |
| Tertiary Lymphoid Structures |
Stimulate |
18460737 |
| Thyroid Cancer Papillary |
Associate |
32031754 |
| Tn Syndrome |
Associate |
35628426 |
| Tooth Diseases |
Associate |
25619900 |
| Triple Negative Breast Neoplasms |
Associate |
31182923, 35017469, 38104484 |
| Urethral Neoplasms |
Associate |
31382611 |
| Urinary Bladder Diseases |
Associate |
25402510 |
| Urinary Bladder Neoplasms |
Associate |
18930813, 24219772, 24494199, 24722645, 24919441, 36676755, 37660159 |
| Urolithiasis |
Associate |
37878647 |
| Urologic Neoplasms |
Associate |
31929112 |
| Uterine Cervical Dysplasia |
Associate |
21725155 |
| Uterine Cervical Neoplasms |
Associate |
21319141, 23886214, 24569473, 26490979 |
| Uterine Cervicitis |
Associate |
21725155 |
| Vitreoretinopathy Proliferative |
Associate |
37107562 |
| Weight Loss |
Associate |
22272346 |
| Zika Virus Infection |
Stimulate |
28153732 |
|