Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6629
Gene name Gene Name - the full gene name approved by the HGNC.
Small nuclear ribonucleoprotein polypeptide B2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SNRPB2
Synonyms (NCBI Gene) Gene synonyms aliases
Msl1, U2B''
Chromosome Chromosome number
20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20p12.1
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A`. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythema
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT030365 hsa-miR-24-3p Microarray 19748357
MIRT031432 hsa-miR-16-5p Proteomics 18668040
MIRT044882 hsa-miR-193a-3p CLASH 23622248
MIRT201474 hsa-miR-5692a PAR-CLIP 20371350
MIRT201466 hsa-miR-1277-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000398 Process MRNA splicing, via spliceosome IBA 21873635
GO:0000398 Process MRNA splicing, via spliceosome IC 2951739, 9731529, 11991638
GO:0000398 Process MRNA splicing, via spliceosome IDA 28076346, 28781166
GO:0000398 Process MRNA splicing, via spliceosome TAS
GO:0001650 Component Fibrillar center IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603520 11155 ENSG00000125870
Protein
UniProt ID P08579
Protein name U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Protein function Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubM
PDB 1A9N , 5MQF , 5O9Z , 5XJC , 5YZG , 5Z56 , 5Z57 , 5Z58 , 6AH0 , 6AHD , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 6QX9 , 6Y53 , 6Y5Q , 7A5P , 7ABG , 7ABI , 7EVO , 7VPX , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8H6E , 8H6J , 8H6K , 8H6L , 8HK1 , 8I0P , 8I0R , 8I0S , 8I0T , 8I0U , 8I0V , 8I0W , 8QO9 , 8QXD , 8QZS , 8R08 , 8R09 , 8R0A , 8R0B , 8RM5 , 9FMD
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 9 80 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 153 219 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Sequence
Sequence length 225
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Spliceosome   mRNA Splicing - Major Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)