SNRPB2 (small nuclear ribonucleoprotein polypeptide B2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6629 |
| Gene name | Small nuclear ribonucleoprotein polypeptide B2 |
| Gene symbol | SNRPB2 |
| Synonyms (NCBI Gene) |
Msl1U2B''
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| Chromosome | 20 |
| Chromosome location | 20p12.1 |
| Summary | The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A`. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythema |
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miRNA
miRNA information provided by mirtarbase database.
614
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P08579 | |||||||||||||||
| Protein name | U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'') | |||||||||||||||
| Protein function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:32494006). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubM | |||||||||||||||
| PDB | 1A9N , 5MQF , 5O9Z , 5XJC , 5YZG , 5Z56 , 5Z57 , 5Z58 , 6AH0 , 6AHD , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 6QX9 , 6Y53 , 6Y5Q , 7A5P , 7ABG , 7ABI , 7EVO , 7VPX , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8H6E , 8H6J , 8H6K , 8H6L , 8HK1 , 8I0P , 8I0R , 8I0S , 8I0T , 8I0U , 8I0V , 8I0W , 8QO9 , 8QXD , 8QZS , 8R08 , 8R09 , 8R0A , 8R0B , 8RM5 , 9FMD | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 225 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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