Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	65980
Gene name Gene Name - the full gene name approved by the HGNC.	Bromodomain containing 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BRD9
Synonyms (NCBI Gene) Gene synonyms aliases	LAVS3040, PRO9856, SMARCI2
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5p15.33

Show/Hide all(95)

miRTarBase ID	miRNA	Experiments	Reference
MIRT728197	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT728196	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT824540	hsa-miR-1231	CLIP-seq
MIRT824541	hsa-miR-150	CLIP-seq
MIRT824542	hsa-miR-1914	CLIP-seq
MIRT824543	hsa-miR-2115	CLIP-seq
MIRT824544	hsa-miR-329	CLIP-seq
MIRT824545	hsa-miR-335	CLIP-seq
MIRT824546	hsa-miR-3618	CLIP-seq
MIRT824547	hsa-miR-362-3p	CLIP-seq
MIRT824548	hsa-miR-3973	CLIP-seq
MIRT824549	hsa-miR-4288	CLIP-seq
MIRT824550	hsa-miR-4436a	CLIP-seq
MIRT824551	hsa-miR-4502	CLIP-seq
MIRT824552	hsa-miR-4670-5p	CLIP-seq
MIRT824553	hsa-miR-516a-3p	CLIP-seq
MIRT824554	hsa-miR-520g	CLIP-seq
MIRT824555	hsa-miR-520h	CLIP-seq
MIRT824556	hsa-miR-548ae	CLIP-seq
MIRT824557	hsa-miR-548aj	CLIP-seq
MIRT824558	hsa-miR-548am	CLIP-seq
MIRT824559	hsa-miR-548x	CLIP-seq
MIRT824560	hsa-miR-550a	CLIP-seq
MIRT824561	hsa-miR-632	CLIP-seq
MIRT824562	hsa-miR-934	CLIP-seq
MIRT824563	hsa-miR-140-3p	CLIP-seq
MIRT824564	hsa-miR-1915	CLIP-seq
MIRT824565	hsa-miR-3155	CLIP-seq
MIRT824566	hsa-miR-3155b	CLIP-seq
MIRT824567	hsa-miR-4275	CLIP-seq
MIRT824568	hsa-miR-4726-3p	CLIP-seq
MIRT824569	hsa-miR-483-3p	CLIP-seq
MIRT824570	hsa-miR-484	CLIP-seq
MIRT824571	hsa-miR-628-5p	CLIP-seq
MIRT1943726	hsa-miR-1324	CLIP-seq
MIRT1943727	hsa-miR-3151	CLIP-seq
MIRT1943728	hsa-miR-3166	CLIP-seq
MIRT1943729	hsa-miR-4257	CLIP-seq
MIRT824550	hsa-miR-4436a	CLIP-seq
MIRT1943730	hsa-miR-4462	CLIP-seq
MIRT1943731	hsa-miR-486-3p	CLIP-seq
MIRT824546	hsa-miR-3618	CLIP-seq
MIRT2182459	hsa-miR-425	CLIP-seq
MIRT824569	hsa-miR-483-3p	CLIP-seq
MIRT2182460	hsa-miR-603	CLIP-seq
MIRT2182461	hsa-miR-873	CLIP-seq
MIRT824562	hsa-miR-934	CLIP-seq
MIRT2486123	hsa-miR-1266	CLIP-seq
MIRT2486124	hsa-miR-1270	CLIP-seq
MIRT1943726	hsa-miR-1324	CLIP-seq
MIRT824563	hsa-miR-140-3p	CLIP-seq
MIRT824541	hsa-miR-150	CLIP-seq
MIRT824542	hsa-miR-1914	CLIP-seq
MIRT1943727	hsa-miR-3151	CLIP-seq
MIRT1943728	hsa-miR-3166	CLIP-seq
MIRT2486125	hsa-miR-3187-3p	CLIP-seq
MIRT824544	hsa-miR-329	CLIP-seq
MIRT824545	hsa-miR-335	CLIP-seq
MIRT824546	hsa-miR-3618	CLIP-seq
MIRT824547	hsa-miR-362-3p	CLIP-seq
MIRT2486126	hsa-miR-3677-3p	CLIP-seq
MIRT1943729	hsa-miR-4257	CLIP-seq
MIRT2486127	hsa-miR-4283	CLIP-seq
MIRT2486128	hsa-miR-432	CLIP-seq
MIRT824550	hsa-miR-4436a	CLIP-seq
MIRT1943730	hsa-miR-4462	CLIP-seq
MIRT2486129	hsa-miR-4489	CLIP-seq
MIRT2486130	hsa-miR-4518	CLIP-seq
MIRT2486131	hsa-miR-4522	CLIP-seq
MIRT2486132	hsa-miR-4529-5p	CLIP-seq
MIRT2486133	hsa-miR-4531	CLIP-seq
MIRT824552	hsa-miR-4670-5p	CLIP-seq
MIRT2486134	hsa-miR-4760-3p	CLIP-seq
MIRT2486135	hsa-miR-4777-3p	CLIP-seq
MIRT824569	hsa-miR-483-3p	CLIP-seq
MIRT1943731	hsa-miR-486-3p	CLIP-seq
MIRT824560	hsa-miR-550a	CLIP-seq
MIRT2486136	hsa-miR-620	CLIP-seq
MIRT2486137	hsa-miR-664	CLIP-seq
MIRT824562	hsa-miR-934	CLIP-seq
MIRT1943726	hsa-miR-1324	CLIP-seq
MIRT824541	hsa-miR-150	CLIP-seq
MIRT824542	hsa-miR-1914	CLIP-seq
MIRT1943727	hsa-miR-3151	CLIP-seq
MIRT1943728	hsa-miR-3166	CLIP-seq
MIRT824544	hsa-miR-329	CLIP-seq
MIRT824545	hsa-miR-335	CLIP-seq
MIRT824546	hsa-miR-3618	CLIP-seq
MIRT824547	hsa-miR-362-3p	CLIP-seq
MIRT1943729	hsa-miR-4257	CLIP-seq
MIRT824550	hsa-miR-4436a	CLIP-seq
MIRT824552	hsa-miR-4670-5p	CLIP-seq
MIRT1943731	hsa-miR-486-3p	CLIP-seq
MIRT824560	hsa-miR-550a	CLIP-seq
MIRT824562	hsa-miR-934	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	NAS	18559093
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	IDA
GO:0006325	Process	Chromatin organization	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0008150	Process	Biological_process	ND
GO:0016514	Component	SWI/SNF complex	IDA	29374058
GO:0070577	Function	Lysine-acetylated histone binding	IBA	21873635
GO:0070577	Function	Lysine-acetylated histone binding	IDA	22464331

MIM	HGNC	e!Ensembl
618465	25818	ENSG00000028310

Protein

UniProt ID

Q9H8M2

Protein name

Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS-40.8)

Protein function

Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:263657

PDB

3HME , 4NQN , 4UIT , 4UIU , 4UIV , 4UIW , 4XY8 , 4YY4 , 4YY6 , 4YYD , 4YYG , 4YYH , 4YYI , 4YYJ , 4YYK , 4Z6H , 4Z6I , 5E9V , 5EU1 , 5F1H , 5F1L , 5F25 , 5F2P , 5I40 , 5I7X , 5I7Y , 5IGM , 5IGN , 5JI8 , 5MKY , 5TWX , 6BQA , 6HM0 , 6UZF , 6V0S , 6V0X , 6V14 , 6V1B , 6Y7H , 6Y7I , 6Y7J , 6Y7K , 6Y7L , 6YQR , 6YQS , 6YQW , 8A7I , 8AHC

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00439	Bromodomain	142 → 228	Bromodomain	Domain
PF12024	DUF3512	286 → 465	Domain of unknown function (DUF3512)	Family

Sequence

MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT

Sequence length

597

Interactions

View interactions

	KEGG
	ATP-dependent chromatin remodeling

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Sezary syndrome	Sezary Syndrome	rs587776632	26551667

Show/Hide Text Mining Associations (35)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenoma	Associate	29575536
Aggressive Periodontitis	Associate	36918560
Bisphosphonate Associated Osteonecrosis of the Jaw	Associate	36918560
Bone Diseases	Associate	36918560
Breast Neoplasms	Associate	32276436, 37870468
Calcinosis Cutis	Stimulate	34944438
Carcinogenesis	Associate	29575536, 38255982
Carcinoma Hepatocellular	Associate	34415102, 38303608
Carcinoma Renal Cell	Associate	34415102
Colonic Neoplasms	Associate	35778964
Colorectal Neoplasms	Associate	35778964, 36297001
Hematologic Diseases	Associate	36918560
Hereditary Autoinflammatory Diseases	Associate	34397140
Inflammation	Associate	35853853
Leiomyoma	Stimulate	38255982
Leiomyosarcoma	Stimulate	35883603
Leukemia	Associate	31000698, 35853853
Leukemia Myeloid Acute	Associate	31000698, 34415102, 35853853, 38126767
Lung Neoplasms	Associate	29981437
Melanoma	Associate	38070581, 38303608
Melanoma Cutaneous Malignant	Associate	38070581
Multiple Myeloma	Associate	35853853, 36780189
Neoplasms	Associate	29575536, 30397315, 31504061, 34415102, 37870468, 38070581, 38126767
Neoplasms	Stimulate	38303608
Neoplasms Squamous Cell	Associate	34415102
Neoplastic Syndromes Hereditary	Associate	32276436
Prostatic Neoplasms	Stimulate	34944438
Pulmonary Disease Chronic Obstructive	Associate	35778964
Rhabdoid Tumor	Associate	31015438
Sarcoma	Associate	35853853
Sarcoma Synovial	Inhibit	30397315
Sarcoma Synovial	Associate	30431433
Thyroid Cancer Papillary	Associate	32065787
Triple Negative Breast Neoplasms	Associate	31000582
Uterine Cervical Neoplasms	Associate	18559093

BRD9 (bromodomain containing 9)