Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6563
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 14 member 1 (Kidd blood group)
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC14A1
Synonyms (NCBI Gene) Gene synonyms aliases	HUT11, HUT11A, HsT1341, JK, Jk(a), Jk(b), RACH1, RACH2, UT-B1, UT1, UTE
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q12.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009]

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miRTarBase ID	miRNA	Experiments	Reference
MIRT443546	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT443546	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT1352530	hsa-miR-1224-3p	CLIP-seq
MIRT1352531	hsa-miR-1256	CLIP-seq
MIRT1352532	hsa-miR-1260	CLIP-seq
MIRT1352533	hsa-miR-1260b	CLIP-seq
MIRT1352534	hsa-miR-1276	CLIP-seq
MIRT1352535	hsa-miR-1280	CLIP-seq
MIRT1352536	hsa-miR-150	CLIP-seq
MIRT1352537	hsa-miR-188-3p	CLIP-seq
MIRT1352538	hsa-miR-2052	CLIP-seq
MIRT1352539	hsa-miR-3125	CLIP-seq
MIRT1352540	hsa-miR-3148	CLIP-seq
MIRT1352541	hsa-miR-3156-3p	CLIP-seq
MIRT1352542	hsa-miR-3688-5p	CLIP-seq
MIRT1352543	hsa-miR-3916	CLIP-seq
MIRT1352544	hsa-miR-4269	CLIP-seq
MIRT1352545	hsa-miR-4311	CLIP-seq
MIRT1352546	hsa-miR-4438	CLIP-seq
MIRT1352547	hsa-miR-4446-5p	CLIP-seq
MIRT1352548	hsa-miR-4474-3p	CLIP-seq
MIRT1352549	hsa-miR-500a	CLIP-seq
MIRT1352550	hsa-miR-5095	CLIP-seq
MIRT1352551	hsa-miR-520d-5p	CLIP-seq
MIRT1352552	hsa-miR-524-5p	CLIP-seq
MIRT1352553	hsa-miR-562	CLIP-seq
MIRT1352554	hsa-miR-570	CLIP-seq
MIRT1352555	hsa-miR-583	CLIP-seq
MIRT1352556	hsa-miR-1343	CLIP-seq
MIRT1352557	hsa-miR-1913	CLIP-seq
MIRT1352538	hsa-miR-2052	CLIP-seq
MIRT1352558	hsa-miR-3120-3p	CLIP-seq
MIRT1352559	hsa-miR-324-3p	CLIP-seq
MIRT1352560	hsa-miR-3616-5p	CLIP-seq
MIRT1352561	hsa-miR-3646	CLIP-seq
MIRT1352562	hsa-miR-3647-5p	CLIP-seq
MIRT1352563	hsa-miR-3942-5p	CLIP-seq
MIRT1352564	hsa-miR-3978	CLIP-seq
MIRT1352565	hsa-miR-4703-5p	CLIP-seq
MIRT1352566	hsa-miR-4707-3p	CLIP-seq
MIRT1352567	hsa-miR-4795-5p	CLIP-seq
MIRT1352568	hsa-miR-498	CLIP-seq
MIRT1352569	hsa-miR-515-5p	CLIP-seq
MIRT1352570	hsa-miR-548a-5p	CLIP-seq
MIRT1352571	hsa-miR-548ab	CLIP-seq
MIRT1352572	hsa-miR-548ak	CLIP-seq
MIRT1352573	hsa-miR-548b-5p	CLIP-seq
MIRT1352574	hsa-miR-548c-5p	CLIP-seq
MIRT1352575	hsa-miR-548d-5p	CLIP-seq
MIRT1352576	hsa-miR-548h	CLIP-seq
MIRT1352577	hsa-miR-548i	CLIP-seq
MIRT1352578	hsa-miR-548j	CLIP-seq
MIRT1352579	hsa-miR-548w	CLIP-seq
MIRT1352580	hsa-miR-548y	CLIP-seq
MIRT1352581	hsa-miR-559	CLIP-seq
MIRT1352582	hsa-miR-573	CLIP-seq
MIRT1352583	hsa-miR-129-3p	CLIP-seq
MIRT1352558	hsa-miR-3120-3p	CLIP-seq
MIRT1352563	hsa-miR-3942-5p	CLIP-seq
MIRT1352584	hsa-miR-4690-3p	CLIP-seq
MIRT1352565	hsa-miR-4703-5p	CLIP-seq
MIRT1352585	hsa-miR-512-5p	CLIP-seq
MIRT1352569	hsa-miR-515-5p	CLIP-seq
MIRT1352556	hsa-miR-1343	CLIP-seq
MIRT1352586	hsa-miR-335	CLIP-seq
MIRT1352587	hsa-miR-3545-3p	CLIP-seq
MIRT1352588	hsa-miR-3622a-3p	CLIP-seq
MIRT1352589	hsa-miR-3622b-3p	CLIP-seq
MIRT1352590	hsa-miR-378g	CLIP-seq
MIRT1352591	hsa-miR-4437	CLIP-seq
MIRT1352592	hsa-miR-4635	CLIP-seq
MIRT1352593	hsa-miR-4674	CLIP-seq
MIRT1352594	hsa-miR-4680-5p	CLIP-seq
MIRT1352595	hsa-miR-499-3p	CLIP-seq
MIRT1352596	hsa-miR-499a-3p	CLIP-seq
MIRT1352597	hsa-miR-587	CLIP-seq
MIRT2104369	hsa-miR-1182	CLIP-seq
MIRT2104370	hsa-miR-1254	CLIP-seq
MIRT2104371	hsa-miR-1910	CLIP-seq
MIRT2104372	hsa-miR-193a-5p	CLIP-seq
MIRT2104373	hsa-miR-200b	CLIP-seq
MIRT2104374	hsa-miR-200c	CLIP-seq
MIRT2104375	hsa-miR-3116	CLIP-seq
MIRT2104376	hsa-miR-3135b	CLIP-seq
MIRT2104377	hsa-miR-3143	CLIP-seq
MIRT2104378	hsa-miR-377	CLIP-seq
MIRT2104379	hsa-miR-423-3p	CLIP-seq
MIRT1352544	hsa-miR-4269	CLIP-seq
MIRT2104380	hsa-miR-4287	CLIP-seq
MIRT2104381	hsa-miR-429	CLIP-seq
MIRT2104382	hsa-miR-431	CLIP-seq
MIRT2104383	hsa-miR-4421	CLIP-seq
MIRT1352546	hsa-miR-4438	CLIP-seq
MIRT2104384	hsa-miR-4469	CLIP-seq
MIRT2104385	hsa-miR-4496	CLIP-seq
MIRT2104386	hsa-miR-452	CLIP-seq
MIRT2104387	hsa-miR-4676-3p	CLIP-seq
MIRT2104388	hsa-miR-4685-3p	CLIP-seq
MIRT2104389	hsa-miR-4735-5p	CLIP-seq
MIRT2104390	hsa-miR-4775	CLIP-seq
MIRT2104391	hsa-miR-4794	CLIP-seq
MIRT1352550	hsa-miR-5095	CLIP-seq
MIRT2104392	hsa-miR-590-3p	CLIP-seq
MIRT2104393	hsa-miR-642a	CLIP-seq
MIRT2104394	hsa-miR-661	CLIP-seq
MIRT2328827	hsa-miR-122	CLIP-seq
MIRT1352556	hsa-miR-1343	CLIP-seq
MIRT2104371	hsa-miR-1910	CLIP-seq
MIRT2328828	hsa-miR-223	CLIP-seq
MIRT2328829	hsa-miR-3198	CLIP-seq
MIRT1352587	hsa-miR-3545-3p	CLIP-seq
MIRT2328830	hsa-miR-3663-5p	CLIP-seq
MIRT1352590	hsa-miR-378g	CLIP-seq
MIRT2104380	hsa-miR-4287	CLIP-seq
MIRT2328831	hsa-miR-4309	CLIP-seq
MIRT2104383	hsa-miR-4421	CLIP-seq
MIRT1352591	hsa-miR-4437	CLIP-seq
MIRT1352546	hsa-miR-4438	CLIP-seq
MIRT2104384	hsa-miR-4469	CLIP-seq
MIRT1352592	hsa-miR-4635	CLIP-seq
MIRT1352593	hsa-miR-4674	CLIP-seq
MIRT1352594	hsa-miR-4680-5p	CLIP-seq
MIRT2104388	hsa-miR-4685-3p	CLIP-seq
MIRT2328832	hsa-miR-4697-3p	CLIP-seq
MIRT2328833	hsa-miR-4713-5p	CLIP-seq
MIRT2328834	hsa-miR-4726-3p	CLIP-seq
MIRT1352568	hsa-miR-498	CLIP-seq
MIRT2328835	hsa-miR-501-5p	CLIP-seq
MIRT1352550	hsa-miR-5095	CLIP-seq
MIRT2328836	hsa-miR-622	CLIP-seq
MIRT2104393	hsa-miR-642a	CLIP-seq
MIRT2104394	hsa-miR-661	CLIP-seq
MIRT2104370	hsa-miR-1254	CLIP-seq
MIRT2459484	hsa-miR-129-5p	CLIP-seq
MIRT2104375	hsa-miR-3116	CLIP-seq
MIRT2459485	hsa-miR-3149	CLIP-seq
MIRT2459486	hsa-miR-3674	CLIP-seq
MIRT2459487	hsa-miR-3935	CLIP-seq
MIRT2104389	hsa-miR-4735-5p	CLIP-seq
MIRT2104390	hsa-miR-4775	CLIP-seq
MIRT2104391	hsa-miR-4794	CLIP-seq
MIRT2104392	hsa-miR-590-3p	CLIP-seq
MIRT2104394	hsa-miR-661	CLIP-seq
MIRT2328827	hsa-miR-122	CLIP-seq
MIRT2104370	hsa-miR-1254	CLIP-seq
MIRT2459484	hsa-miR-129-5p	CLIP-seq
MIRT2104375	hsa-miR-3116	CLIP-seq
MIRT2459485	hsa-miR-3149	CLIP-seq
MIRT2328829	hsa-miR-3198	CLIP-seq
MIRT2459486	hsa-miR-3674	CLIP-seq
MIRT2459487	hsa-miR-3935	CLIP-seq
MIRT1352544	hsa-miR-4269	CLIP-seq
MIRT2328831	hsa-miR-4309	CLIP-seq
MIRT1352546	hsa-miR-4438	CLIP-seq
MIRT2328834	hsa-miR-4726-3p	CLIP-seq
MIRT2104389	hsa-miR-4735-5p	CLIP-seq
MIRT2104390	hsa-miR-4775	CLIP-seq
MIRT2104391	hsa-miR-4794	CLIP-seq
MIRT1352550	hsa-miR-5095	CLIP-seq
MIRT2104392	hsa-miR-590-3p	CLIP-seq
MIRT2104394	hsa-miR-661	CLIP-seq
MIRT2104370	hsa-miR-1254	CLIP-seq
MIRT2459484	hsa-miR-129-5p	CLIP-seq
MIRT2690878	hsa-miR-1299	CLIP-seq
MIRT2104375	hsa-miR-3116	CLIP-seq
MIRT2459485	hsa-miR-3149	CLIP-seq
MIRT2459486	hsa-miR-3674	CLIP-seq
MIRT2459487	hsa-miR-3935	CLIP-seq
MIRT1352544	hsa-miR-4269	CLIP-seq
MIRT1352546	hsa-miR-4438	CLIP-seq
MIRT2104389	hsa-miR-4735-5p	CLIP-seq
MIRT2104390	hsa-miR-4775	CLIP-seq
MIRT2690879	hsa-miR-4782-5p	CLIP-seq
MIRT2104391	hsa-miR-4794	CLIP-seq
MIRT1352550	hsa-miR-5095	CLIP-seq
MIRT2690880	hsa-miR-516b	CLIP-seq
MIRT2104392	hsa-miR-590-3p	CLIP-seq
MIRT2104394	hsa-miR-661	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005372	Function	Water transmembrane transporter activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IDA	7797558, 10514515, 19865084
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	7797558, 7989337
GO:0006833	Process	Water transport	IEA
GO:0015204	Function	Urea transmembrane transporter activity	IDA	7797558, 7989337, 8997401, 10514515
GO:0015204	Function	Urea transmembrane transporter activity	IEA
GO:0015204	Function	Urea transmembrane transporter activity	TAS
GO:0015265	Function	Urea channel activity	IDA	19865084
GO:0015840	Process	Urea transport	IEA
GO:0015840	Process	Urea transport	TAS	7989337
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	ISS
GO:0051649	Process	Establishment of localization in cell	IEA
GO:0055085	Process	Transmembrane transport	TAS
GO:0071918	Process	Urea transmembrane transport	IBA
GO:0071918	Process	Urea transmembrane transport	IDA	19865084
GO:0071918	Process	Urea transmembrane transport	IEA

MIM	HGNC	e!Ensembl
613868	10918	ENSG00000141469

Protein

UniProt ID

Q13336

Protein name

Urea transporter 1 (Solute carrier family 14 member 1) (Urea transporter, erythrocyte)

Protein function

Mediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:10514515, PubMed:7797558, PubMed:7989337, PubMed:8997401). Also mediates the transport of urea across the cell membrane of the ren

PDB

6QD5 , 8BLP , 8XDF

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03253	UT	59 → 354	Urea transporter	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in erythrocytes (at protein level) (PubMed:23219802). Expressed in spleen erythroblasts and tumoral kidney (PubMed:7989337). {ECO:0000269|PubMed:23219802, ECO:0000269|PubMed:7989337}.

Sequence

MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
KMPLSKVTYPEENRIFYLQAKKRMVESPL

Sequence length

389

Interactions

View interactions

	Reactome
			Transport of bile salts and organic acids, metal ions and amine compounds

SLC14A1 (solute carrier family 14 member 1 (Kidd blood group))