SLC6A6 (solute carrier family 6 member 6)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6533 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 6 member 6 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC6A6 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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HTRDC, TAUT |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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HTRDC |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p25.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative spli |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P31641 | ||||||||||
Protein name | Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) | ||||||||||
Protein function | Mediates sodium- and chloride-dependent transport of taurine (PubMed:31345061, PubMed:31903486, PubMed:8010975, PubMed:8382624, PubMed:8654117). Mediates transport of beta-alanine (PubMed:8010975). Can also mediate transport of hypotaurine and g | ||||||||||
PDB | 9K7B , 9K7N | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. {ECO:0000269|PubMed:8010975, ECO:0000269|PubMed:8382624}. | ||||||||||
Sequence | |||||||||||
Sequence length | 620 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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