PRB2 (proline rich protein BstNI subfamily 2)

Gene

• Entrez ID: 653247
• Gene name: Proline rich protein BstNI subfamily 2
• Gene symbol: PRB2
• Synonyms (NCBI Gene): IB-9, PRPPRB1, Ps, cP7
• Chromosome: 12
• Chromosome location: 12p13.2
• Summary: This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid glands. Multi

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022539	hsa-miR-124-3p	Microarray	18668037

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA

Other IDs

• MIM: 168810
• HGNC: 9338
• e!Ensembl: ENSG00000121335

Protein

• UniProt ID: P02812
• Protein name: Basic salivary proline-rich protein 2 (Salivary proline-rich protein) (Con1 glycoprotein) [Cleaved into: Basic proline-rich peptide IB-1; Basic proline-rich peptide P-E (IB-9); Basic proline-rich peptide IB-7; Basic proline-rich peptide IB-8c (Basic pepti
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15240	Pro-rich	1 → 135	Proline-rich	Disordered
  PF15240	Pro-rich	167 → 239	Proline-rich	Disordered
  PF15240	Pro-rich	229 → 300	Proline-rich	Disordered
  PF15240	Pro-rich	315 → 416	Proline-rich	Disordered

• Sequence:

  MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP
  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG
  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP
  QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG
  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKSQGPPPPGKPQGPPPQGGSKSRSSRSP
  PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR
  SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ

• Sequence length: 416

Pathways

KEGG:

Salivary secretion