Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6526
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 5 member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC5A3
Synonyms (NCBI Gene) Gene synonyms aliases
BCW2, SMIT, SMIT1, SMIT2
Chromosome Chromosome number
21
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
21q22.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018102 hsa-miR-335-5p Microarray 18185580
MIRT020185 hsa-miR-130b-3p Sequencing 20371350
MIRT022015 hsa-miR-128-3p Sequencing 20371350
MIRT028159 hsa-miR-93-5p Sequencing 20371350
MIRT029655 hsa-miR-26b-5p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005365 Function Myo-inositol transmembrane transporter activity ISS
GO:0005367 Function Myo-inositol:sodium symporter activity ISS
GO:0005367 Function Myo-inositol:sodium symporter activity TAS
GO:0005412 Function Glucose:sodium symporter activity IBA 21873635
GO:0005412 Function Glucose:sodium symporter activity ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
600444 11038 ENSG00000198743
Protein
UniProt ID P53794
Protein name Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3)
Protein function Electrogenic Na(+)-coupled sugar symporter that actively transports myo-inositol and its stereoisomer scyllo-inositol across the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1 (By similarity). Maintains myo-inositol concentration g
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00474 SSF 39 477 Sodium:solute symporter family Family
Sequence
Sequence length 718
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Papillary renal carcinoma Papillary Renal Cell Carcinoma rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724 25401301
Renal carcinoma Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney rs121913668, rs121913670, rs121913243, rs786202724 25401301
Unknown
Disease term Disease name Evidence References Source
Chromophobe carcinoma Chromophobe Renal Cell Carcinoma 25401301 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 27294516
Alzheimer Disease Associate 34668150
Bipolar Disorder Stimulate 16420717
Dermatomyositis Associate 27322952
Down Syndrome Associate 10393611
Inflammation Associate 27322952, 32235474
Leiomyoma Associate 21496801, 30567472
Muscular Disorders Atrophic Associate 27322952
Myocardial Infarction Associate 25697262
Myositis Associate 32235474