Gene Gene information from NCBI Gene database.
Entrez ID 6515
Gene name Solute carrier family 2 member 3
Gene symbol SLC2A3
Synonyms (NCBI Gene)
GLUT3
Chromosome 12
Chromosome location 12p13.31
miRNA miRNA information provided by mirtarbase database.
821
miRTarBase ID miRNA Experiments Reference
MIRT006235 hsa-miR-195-5p Luciferase reporter assayWestern blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assayWestern blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assayWestern blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assayWestern blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assayWestern blot 22265971
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Transcription factor Regulation Reference
HMGA1 Activation 22706202
ZBTB7A Repression 25184678
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
39
GO ID Ontology Definition Evidence Reference
GO:0005353 Function Fructose transmembrane transporter activity IDA 8457197
GO:0005354 Function Galactose transmembrane transporter activity IDA 8457197
GO:0005515 Function Protein binding IPI 32296183, 35810171
GO:0005536 Function D-glucose binding IDA 26176916
GO:0005886 Component Plasma membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
138170 11007 ENSG00000059804
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P11169
Protein name Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)
Protein function Facilitative glucose transporter (PubMed:26176916, PubMed:32860739, PubMed:9477959). Can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:26176916, PubMed:9477959). Mediates the uptake of glucose, 2-deoxy
PDB 4ZW9 , 4ZWB , 4ZWC , 5C65 , 7CRZ , 7SPS , 7SPT
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00083 Sugar_tr 13 465 Sugar (and other) transporter Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in brain (PubMed:8457197). Expressed in many tissues. {ECO:0000269|PubMed:3170580, ECO:0000269|PubMed:8457197}.
Sequence
Sequence length 496
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Cellular hexose transport
Vitamin C (ascorbate) metabolism
Neutrophil degranulation