Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6515
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 2 member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC2A3
Synonyms (NCBI Gene) Gene synonyms aliases
GLUT3
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.31
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT006235 hsa-miR-195-5p Luciferase reporter assay, Western blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assay, Western blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assay, Western blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assay, Western blot 22265971
MIRT006235 hsa-miR-195-5p Luciferase reporter assay, Western blot 22265971
Transcription factors
Transcription factor Regulation Reference
HMGA1 Activation 22706202
ZBTB7A Repression 25184678
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005355 Function Glucose transmembrane transporter activity IDA 26176916
GO:0005515 Function Protein binding IPI 25893612, 32296183
GO:0005536 Function Glucose binding IDA 26176916
GO:0005886 Component Plasma membrane ISS
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
138170 11007 ENSG00000059804
Protein
UniProt ID P11169
Protein name Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)
Protein function Facilitative glucose transporter (PubMed:26176916, PubMed:32860739, PubMed:9477959). Can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:26176916, PubMed:9477959). Mediates the uptake of glucose, 2-deoxy
PDB 4ZW9 , 4ZWB , 4ZWC , 5C65 , 7CRZ , 7SPS , 7SPT
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00083 Sugar_tr 13 465 Sugar (and other) transporter Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in brain (PubMed:8457197). Expressed in many tissues. {ECO:0000269|PubMed:3170580, ECO:0000269|PubMed:8457197}.
Sequence
Sequence length 496
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Cellular hexose transport
Vitamin C (ascorbate) metabolism
Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Arthritis Juvenile arthritis rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 19565504
Neoplasm Neoplasms, Germ Cell and Embryonal, Neoplasms, Embryonal and Mixed rs137854562, rs137854565, rs137854568, rs137854574, rs121434220, rs121909218, rs121909222, rs587776667, rs606231169, rs587776701, rs121913388, rs137852578, rs137852216, rs121912651, rs28934575
View all (247 more)
16168501
Dermatitis Dermatitis, Allergic Contact rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174 17374397
Developmental regression Developmental regression rs1224421127
Unknown
Disease term Disease name Evidence References Source
Huntington disease Huntington Disease, Huntington disease 24452335 ClinVar
Huntington Disease Huntington disease GenCC
Anxiety Disorder Anxiety Disorder GWAS
Dementia Dementia GWAS
Associations from Text Mining
Disease Name Relationship Type References
22q11 Deletion Syndrome Associate 27604636
Adenocarcinoma Associate 26410497, 34814273
Adenocarcinoma of Lung Associate 24928511
Alzheimer Disease Associate 23341039, 29055815
Arthritis Rheumatoid Associate 24178905
Attention Deficit Disorder with Hyperactivity Associate 29477591
Autistic Disorder Associate 35466476
Blood Platelet Disorders Associate 26367242
Brain Edema Associate 32908869
Breast Neoplasms Associate 22270867, 34525987, 35178446, 35501580, 37222403