RSRC2 (arginine and serine rich coiled-coil 2)

Gene

• Entrez ID: 65117
• Gene name: Arginine and serine rich coiled-coil 2
• Gene symbol: RSRC2
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12q24.31

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs752134549	C>T	Likely-pathogenic	Missense variant, non coding transcript variant, 5 prime UTR variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021137	hsa-miR-186-5p	Sequencing	20371350
MIRT023747	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT029387	hsa-miR-26b-5p	Sequencing	20371350
MIRT048096	hsa-miR-197-3p	CLASH	23622248
MIRT572970	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572971	hsa-miR-6884-3p	PAR-CLIP	20371350
MIRT572970	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572971	hsa-miR-6884-3p	PAR-CLIP	20371350
MIRT468828	hsa-miR-490-3p	PAR-CLIP	20371350
MIRT468827	hsa-miR-649	PAR-CLIP	20371350
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	20371350
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT468824	hsa-miR-4421	PAR-CLIP	20371350
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	20371350
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT468819	hsa-miR-629-5p	PAR-CLIP	20371350
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	20371350
MIRT468816	hsa-miR-4540	PAR-CLIP	20371350
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	20371350
MIRT468814	hsa-miR-552-5p	PAR-CLIP	20371350
MIRT468828	hsa-miR-490-3p	PAR-CLIP	21572407
MIRT468827	hsa-miR-649	PAR-CLIP	21572407
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	21572407
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT468824	hsa-miR-4421	PAR-CLIP	21572407
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT468822	hsa-miR-1237-3p	PAR-CLIP	21572407
MIRT468821	hsa-miR-1248	PAR-CLIP	21572407
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT468819	hsa-miR-629-5p	PAR-CLIP	21572407
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	21572407
MIRT468816	hsa-miR-4540	PAR-CLIP	21572407
MIRT468817	hsa-miR-6868-3p	PAR-CLIP	21572407
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	21572407
MIRT468814	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT468828	hsa-miR-490-3p	PAR-CLIP	23592263
MIRT468827	hsa-miR-649	PAR-CLIP	23592263
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	23592263
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	23592263
MIRT468824	hsa-miR-4421	PAR-CLIP	23592263
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	23592263
MIRT468822	hsa-miR-1237-3p	PAR-CLIP	23592263
MIRT468821	hsa-miR-1248	PAR-CLIP	23592263
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT468819	hsa-miR-629-5p	PAR-CLIP	23592263
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	23592263
MIRT468816	hsa-miR-4540	PAR-CLIP	23592263
MIRT468817	hsa-miR-6868-3p	PAR-CLIP	23592263
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	23592263
MIRT468814	hsa-miR-552-5p	PAR-CLIP	23592263
MIRT572970	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572971	hsa-miR-6884-3p	PAR-CLIP	20371350
MIRT572970	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572971	hsa-miR-6884-3p	PAR-CLIP	20371350
MIRT468828	hsa-miR-490-3p	PAR-CLIP	20371350
MIRT468827	hsa-miR-649	PAR-CLIP	20371350
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	20371350
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	20371350
MIRT468824	hsa-miR-4421	PAR-CLIP	20371350
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	20371350
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT468819	hsa-miR-629-5p	PAR-CLIP	20371350
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	20371350
MIRT468816	hsa-miR-4540	PAR-CLIP	20371350
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	20371350
MIRT468814	hsa-miR-552-5p	PAR-CLIP	20371350
MIRT468828	hsa-miR-490-3p	PAR-CLIP	21572407
MIRT468827	hsa-miR-649	PAR-CLIP	21572407
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	21572407
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	21572407
MIRT468824	hsa-miR-4421	PAR-CLIP	21572407
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	21572407
MIRT468822	hsa-miR-1237-3p	PAR-CLIP	21572407
MIRT468821	hsa-miR-1248	PAR-CLIP	21572407
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT468819	hsa-miR-629-5p	PAR-CLIP	21572407
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	21572407
MIRT468816	hsa-miR-4540	PAR-CLIP	21572407
MIRT468817	hsa-miR-6868-3p	PAR-CLIP	21572407
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	21572407
MIRT468814	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT468828	hsa-miR-490-3p	PAR-CLIP	23592263
MIRT468827	hsa-miR-649	PAR-CLIP	23592263
MIRT468826	hsa-miR-6838-3p	PAR-CLIP	23592263
MIRT468825	hsa-miR-6748-3p	PAR-CLIP	23592263
MIRT468824	hsa-miR-4421	PAR-CLIP	23592263
MIRT468823	hsa-miR-5699-3p	PAR-CLIP	23592263
MIRT468822	hsa-miR-1237-3p	PAR-CLIP	23592263
MIRT468821	hsa-miR-1248	PAR-CLIP	23592263
MIRT468820	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT468819	hsa-miR-629-5p	PAR-CLIP	23592263
MIRT468818	hsa-miR-6793-5p	PAR-CLIP	23592263
MIRT468816	hsa-miR-4540	PAR-CLIP	23592263
MIRT468817	hsa-miR-6868-3p	PAR-CLIP	23592263
MIRT468815	hsa-miR-6839-3p	PAR-CLIP	23592263
MIRT468814	hsa-miR-552-5p	PAR-CLIP	23592263
MIRT1321499	hsa-miR-1237	CLIP-seq
MIRT1321500	hsa-miR-1915	CLIP-seq
MIRT1321501	hsa-miR-200b	CLIP-seq
MIRT1321502	hsa-miR-200c	CLIP-seq
MIRT1321503	hsa-miR-2052	CLIP-seq
MIRT1321504	hsa-miR-3145-3p	CLIP-seq
MIRT1321505	hsa-miR-3149	CLIP-seq
MIRT1321506	hsa-miR-3163	CLIP-seq
MIRT1321507	hsa-miR-34c-3p	CLIP-seq
MIRT1321508	hsa-miR-3591-3p	CLIP-seq
MIRT1321509	hsa-miR-362-5p	CLIP-seq
MIRT1321510	hsa-miR-3691-3p	CLIP-seq
MIRT1321511	hsa-miR-4282	CLIP-seq
MIRT1321512	hsa-miR-429	CLIP-seq
MIRT1321513	hsa-miR-4328	CLIP-seq
MIRT1321514	hsa-miR-4420	CLIP-seq
MIRT1321515	hsa-miR-4427	CLIP-seq
MIRT1321516	hsa-miR-4699-3p	CLIP-seq
MIRT1321517	hsa-miR-4724-5p	CLIP-seq
MIRT1321518	hsa-miR-4726-3p	CLIP-seq
MIRT1321519	hsa-miR-494	CLIP-seq
MIRT1321520	hsa-miR-500b	CLIP-seq
MIRT1321521	hsa-miR-501-5p	CLIP-seq
MIRT1321522	hsa-miR-514	CLIP-seq
MIRT1321523	hsa-miR-514b-3p	CLIP-seq
MIRT1321524	hsa-miR-520d-5p	CLIP-seq
MIRT1321525	hsa-miR-524-5p	CLIP-seq
MIRT1321526	hsa-miR-580	CLIP-seq
MIRT1321527	hsa-miR-621	CLIP-seq
MIRT1321528	hsa-miR-656	CLIP-seq
MIRT2095444	hsa-miR-1287	CLIP-seq
MIRT2095445	hsa-miR-21	CLIP-seq
MIRT2095446	hsa-miR-3135b	CLIP-seq
MIRT2095447	hsa-miR-3920	CLIP-seq
MIRT2095448	hsa-miR-3924	CLIP-seq
MIRT2095449	hsa-miR-4668-3p	CLIP-seq
MIRT2095450	hsa-miR-548c-3p	CLIP-seq
MIRT2095451	hsa-miR-590-5p	CLIP-seq
MIRT2319819	hsa-miR-1178	CLIP-seq
MIRT2319820	hsa-miR-1183	CLIP-seq
MIRT2319821	hsa-miR-1184	CLIP-seq
MIRT2319822	hsa-miR-1224-3p	CLIP-seq
MIRT1321499	hsa-miR-1237	CLIP-seq
MIRT2095444	hsa-miR-1287	CLIP-seq
MIRT2319823	hsa-miR-129-5p	CLIP-seq
MIRT2319824	hsa-miR-1301	CLIP-seq
MIRT2319825	hsa-miR-197	CLIP-seq
MIRT2095445	hsa-miR-21	CLIP-seq
MIRT2319826	hsa-miR-2277-3p	CLIP-seq
MIRT2095446	hsa-miR-3135b	CLIP-seq
MIRT2319827	hsa-miR-3136-5p	CLIP-seq
MIRT1321504	hsa-miR-3145-3p	CLIP-seq
MIRT1321507	hsa-miR-34c-3p	CLIP-seq
MIRT1321508	hsa-miR-3591-3p	CLIP-seq
MIRT1321509	hsa-miR-362-5p	CLIP-seq
MIRT2319828	hsa-miR-3667-3p	CLIP-seq
MIRT2095448	hsa-miR-3924	CLIP-seq
MIRT2319829	hsa-miR-4279	CLIP-seq
MIRT2319830	hsa-miR-4286	CLIP-seq
MIRT1321514	hsa-miR-4420	CLIP-seq
MIRT1321515	hsa-miR-4427	CLIP-seq
MIRT2319831	hsa-miR-4439	CLIP-seq
MIRT2319832	hsa-miR-4660	CLIP-seq
MIRT2095449	hsa-miR-4668-3p	CLIP-seq
MIRT2319833	hsa-miR-4712-3p	CLIP-seq
MIRT2319834	hsa-miR-4716-5p	CLIP-seq
MIRT2319835	hsa-miR-4731-3p	CLIP-seq
MIRT2319836	hsa-miR-4801	CLIP-seq
MIRT1321520	hsa-miR-500b	CLIP-seq
MIRT1321521	hsa-miR-501-5p	CLIP-seq
MIRT2319837	hsa-miR-5047	CLIP-seq
MIRT2095450	hsa-miR-548c-3p	CLIP-seq
MIRT2319838	hsa-miR-548k	CLIP-seq
MIRT2319839	hsa-miR-548n	CLIP-seq
MIRT2095451	hsa-miR-590-5p	CLIP-seq
MIRT2319840	hsa-miR-595	CLIP-seq
MIRT2319841	hsa-miR-624	CLIP-seq
MIRT2319842	hsa-miR-629	CLIP-seq
MIRT2319843	hsa-miR-943	CLIP-seq
MIRT2615674	hsa-miR-1305	CLIP-seq
MIRT1321501	hsa-miR-200b	CLIP-seq
MIRT1321502	hsa-miR-200c	CLIP-seq
MIRT2615675	hsa-miR-2054	CLIP-seq
MIRT1321504	hsa-miR-3145-3p	CLIP-seq
MIRT1321505	hsa-miR-3149	CLIP-seq
MIRT1321506	hsa-miR-3163	CLIP-seq
MIRT1321507	hsa-miR-34c-3p	CLIP-seq
MIRT1321508	hsa-miR-3591-3p	CLIP-seq
MIRT1321510	hsa-miR-3691-3p	CLIP-seq
MIRT2615676	hsa-miR-369-3p	CLIP-seq
MIRT2615677	hsa-miR-374a	CLIP-seq
MIRT2615678	hsa-miR-374b	CLIP-seq
MIRT2615679	hsa-miR-380	CLIP-seq
MIRT2615680	hsa-miR-3913-3p	CLIP-seq
MIRT1321511	hsa-miR-4282	CLIP-seq
MIRT1321512	hsa-miR-429	CLIP-seq
MIRT1321514	hsa-miR-4420	CLIP-seq
MIRT1321515	hsa-miR-4427	CLIP-seq
MIRT2615681	hsa-miR-4643	CLIP-seq
MIRT1321516	hsa-miR-4699-3p	CLIP-seq
MIRT1321517	hsa-miR-4724-5p	CLIP-seq
MIRT2615682	hsa-miR-4796-5p	CLIP-seq
MIRT2615683	hsa-miR-489	CLIP-seq
MIRT1321519	hsa-miR-494	CLIP-seq
MIRT1321522	hsa-miR-514	CLIP-seq
MIRT1321523	hsa-miR-514b-3p	CLIP-seq
MIRT1321524	hsa-miR-520d-5p	CLIP-seq
MIRT1321525	hsa-miR-524-5p	CLIP-seq
MIRT1321527	hsa-miR-621	CLIP-seq
MIRT2615674	hsa-miR-1305	CLIP-seq
MIRT1321504	hsa-miR-3145-3p	CLIP-seq
MIRT1321505	hsa-miR-3149	CLIP-seq
MIRT1321507	hsa-miR-34c-3p	CLIP-seq
MIRT1321508	hsa-miR-3591-3p	CLIP-seq
MIRT2615680	hsa-miR-3913-3p	CLIP-seq
MIRT1321511	hsa-miR-4282	CLIP-seq
MIRT1321514	hsa-miR-4420	CLIP-seq
MIRT1321516	hsa-miR-4699-3p	CLIP-seq
MIRT2615682	hsa-miR-4796-5p	CLIP-seq
MIRT2615683	hsa-miR-489	CLIP-seq
MIRT1321524	hsa-miR-520d-5p	CLIP-seq
MIRT1321525	hsa-miR-524-5p	CLIP-seq
MIRT1321527	hsa-miR-621	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	23602568, 25416956, 32296183, 33961781

Other IDs

• MIM: 619996
• HGNC: 30559
• e!Ensembl: ENSG00000111011

Protein

• UniProt ID: Q7L4I2
• Protein name: Arginine/serine-rich coiled-coil protein 2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15477	SMAP	354 → 423	Small acidic protein family	Family

• Sequence:

  MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK
  HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS
  RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS
  RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA
  RRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMA
  ALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFG
  NKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGM
  GLGFTSSMRGMDAV

• Sequence length: 434

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
RSRC2-related disorder	Uncertain significance	rs2547268877	RCV003982627

Associations from Text Mining
Disease Name	Relationship Type	References
Metabolism Inborn Errors	Associate	30013183
Neoplasms	Inhibit	21036922
Neuroblastoma	Associate	20444257