BMP3 (bone morphogenetic protein 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 651 |
| Gene name | Bone morphogenetic protein 3 |
| Gene symbol | BMP3 |
| Synonyms (NCBI Gene) |
BMP-3A
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| Chromosome | 4 |
| Chromosome location | 4q21.21 |
| Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate |
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miRNA
miRNA information provided by mirtarbase database.
461
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P12645 | ||||||||||
| Protein name | Bone morphogenetic protein 3 (BMP-3) (Bone morphogenetic protein 3A) (BMP-3A) (Osteogenin) | ||||||||||
| Protein function | Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to | ||||||||||
| PDB | 2QCQ | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in adult and fetal cartilage. {ECO:0000269|PubMed:15475196}. | ||||||||||
| Sequence |
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| Sequence length | 472 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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