Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	65061
Gene name Gene Name - the full gene name approved by the HGNC.	Cyclin dependent kinase 15
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CDK15
Synonyms (NCBI Gene) Gene synonyms aliases	ALS2CR7, PFTAIRE2, PFTK2
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q33.1

Show/Hide all(86)

miRTarBase ID	miRNA	Experiments	Reference
MIRT606937	hsa-miR-6782-5p	HITS-CLIP	24906430
MIRT606936	hsa-miR-3184-5p	HITS-CLIP	24906430
MIRT606935	hsa-miR-423-5p	HITS-CLIP	24906430
MIRT606934	hsa-miR-1914-3p	HITS-CLIP	24906430
MIRT606933	hsa-miR-5194	HITS-CLIP	24906430
MIRT606932	hsa-miR-6738-5p	HITS-CLIP	24906430
MIRT606931	hsa-miR-6747-5p	HITS-CLIP	24906430
MIRT606930	hsa-miR-4455	HITS-CLIP	24906430
MIRT607557	hsa-miR-323a-5p	HITS-CLIP	24906430
MIRT607556	hsa-miR-876-3p	HITS-CLIP	24906430
MIRT606929	hsa-miR-3650	HITS-CLIP	24906430
MIRT606928	hsa-miR-3911	HITS-CLIP	24906430
MIRT606927	hsa-miR-644a	HITS-CLIP	24906430
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT606925	hsa-miR-6834-5p	HITS-CLIP	24906430
MIRT606924	hsa-miR-1226-5p	HITS-CLIP	24906430
MIRT606923	hsa-miR-6734-5p	HITS-CLIP	24906430
MIRT606922	hsa-miR-147a	HITS-CLIP	24906430
MIRT606921	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT606937	hsa-miR-6782-5p	HITS-CLIP	24906430
MIRT606936	hsa-miR-3184-5p	HITS-CLIP	24906430
MIRT606935	hsa-miR-423-5p	HITS-CLIP	24906430
MIRT606934	hsa-miR-1914-3p	HITS-CLIP	24906430
MIRT606933	hsa-miR-5194	HITS-CLIP	24906430
MIRT606932	hsa-miR-6738-5p	HITS-CLIP	24906430
MIRT606931	hsa-miR-6747-5p	HITS-CLIP	24906430
MIRT606930	hsa-miR-4455	HITS-CLIP	24906430
MIRT606929	hsa-miR-3650	HITS-CLIP	24906430
MIRT606928	hsa-miR-3911	HITS-CLIP	24906430
MIRT606927	hsa-miR-644a	HITS-CLIP	24906430
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT606925	hsa-miR-6834-5p	HITS-CLIP	24906430
MIRT606924	hsa-miR-1226-5p	HITS-CLIP	24906430
MIRT606923	hsa-miR-6734-5p	HITS-CLIP	24906430
MIRT606922	hsa-miR-147a	HITS-CLIP	24906430
MIRT606921	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT606924	hsa-miR-1226-5p	HITS-CLIP	27418678
MIRT606924	hsa-miR-1226-5p	HITS-CLIP	27418678
MIRT606922	hsa-miR-147a	HITS-CLIP	27418678
MIRT606922	hsa-miR-147a	HITS-CLIP	27418678
MIRT606922	hsa-miR-147a	HITS-CLIP	27418678
MIRT606922	hsa-miR-147a	HITS-CLIP	27418678
MIRT606934	hsa-miR-1914-3p	HITS-CLIP	27418678
MIRT606934	hsa-miR-1914-3p	HITS-CLIP	27418678
MIRT606936	hsa-miR-3184-5p	HITS-CLIP	27418678
MIRT606936	hsa-miR-3184-5p	HITS-CLIP	27418678
MIRT607557	hsa-miR-323a-5p	HITS-CLIP	27418678
MIRT607557	hsa-miR-323a-5p	HITS-CLIP	27418678
MIRT607557	hsa-miR-323a-5p	HITS-CLIP	27418678
MIRT606929	hsa-miR-3650	HITS-CLIP	27418678
MIRT606929	hsa-miR-3650	HITS-CLIP	27418678
MIRT606928	hsa-miR-3911	HITS-CLIP	27418678
MIRT606928	hsa-miR-3911	HITS-CLIP	27418678
MIRT606928	hsa-miR-3911	HITS-CLIP	27418678
MIRT606928	hsa-miR-3911	HITS-CLIP	27418678
MIRT606935	hsa-miR-423-5p	HITS-CLIP	27418678
MIRT606935	hsa-miR-423-5p	HITS-CLIP	27418678
MIRT606930	hsa-miR-4455	HITS-CLIP	27418678
MIRT606930	hsa-miR-4455	HITS-CLIP	27418678
MIRT606933	hsa-miR-5194	HITS-CLIP	27418678
MIRT606933	hsa-miR-5194	HITS-CLIP	27418678
MIRT606921	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606921	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606921	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606921	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT606927	hsa-miR-644a	HITS-CLIP	27418678
MIRT606927	hsa-miR-644a	HITS-CLIP	27418678
MIRT606927	hsa-miR-644a	HITS-CLIP	27418678
MIRT606927	hsa-miR-644a	HITS-CLIP	27418678
MIRT606923	hsa-miR-6734-5p	HITS-CLIP	27418678
MIRT606923	hsa-miR-6734-5p	HITS-CLIP	27418678
MIRT606932	hsa-miR-6738-5p	HITS-CLIP	27418678
MIRT606932	hsa-miR-6738-5p	HITS-CLIP	27418678
MIRT606931	hsa-miR-6747-5p	HITS-CLIP	27418678
MIRT606931	hsa-miR-6747-5p	HITS-CLIP	27418678
MIRT606937	hsa-miR-6782-5p	HITS-CLIP	27418678
MIRT606937	hsa-miR-6782-5p	HITS-CLIP	27418678
MIRT606925	hsa-miR-6834-5p	HITS-CLIP	27418678
MIRT606925	hsa-miR-6834-5p	HITS-CLIP	27418678
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT606926	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT607556	hsa-miR-876-3p	HITS-CLIP	27418678
MIRT607556	hsa-miR-876-3p	HITS-CLIP	27418678
MIRT607556	hsa-miR-876-3p	HITS-CLIP	27418678

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	24866247
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IBA
GO:0004693	Function	Cyclin-dependent protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	22939624, 23602568, 25036637, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005829	Component	Cytosol	IBA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030332	Function	Cyclin binding	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1901987	Process	Regulation of cell cycle phase transition	IBA

MIM	HGNC	e!Ensembl
616147	14434	ENSG00000138395

Protein

UniProt ID

Q96Q40

Protein name

Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)

Protein function

Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	103 → 387	Protein kinase domain	Domain

Sequence

MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGL
QAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
MHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEA
EDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLA
SYQKGHHPAQFSKCW

Sequence length

435

Interactions

View interactions

CDK15 (cyclin dependent kinase 15)