SLC1A2 (solute carrier family 1 member 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6506 |
| Gene name | Solute carrier family 1 member 2 |
| Gene symbol | SLC1A2 |
| Synonyms (NCBI Gene) |
DEE41EAAT2EIEE41GLT-1GLT1HBGT
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| Chromosome | 11 |
| Chromosome location | 11p13 |
| Summary | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Gl |
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SNPs
SNP information provided by dbSNP.
3
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miRNA
miRNA information provided by mirtarbase database.
648
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
74
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P43004 | ||||||||||
| Protein name | Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) | ||||||||||
| Protein function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:14506254, PubMed:15265858, PubMed:26690923, PubMed:7521911). Functions as a symporter that transports one | ||||||||||
| PDB | 7VR7 , 7VR8 , 7XR4 , 7XR6 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 574 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
68
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