SLC1A2 (solute carrier family 1 member 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6506 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 1 member 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC1A2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Gl |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P43004 | ||||||||||
| Protein name | Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) | ||||||||||
| Protein function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:14506254, PubMed:15265858, PubMed:26690923, PubMed:7521911). Functions as a symporter that transports one | ||||||||||
| PDB | 7VR7 , 7VR8 , 7XR4 , 7XR6 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 574 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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