NT5DC2 (5'-nucleotidase domain containing 2)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64943
Gene name Gene Name - the full gene name approved by the HGNC.
5'-nucleotidase domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NT5DC2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p21.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(11)
miRTarBase ID miRNA Experiments Reference
MIRT030270 hsa-miR-26b-5p Microarray 19088304
MIRT052241 hsa-let-7b-5p CLASH 23622248
MIRT051686 hsa-let-7e-5p CLASH 23622248
MIRT051291 hsa-miR-16-5p CLASH 23622248
MIRT046905 hsa-miR-221-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(3)
GO ID Ontology Definition Evidence Reference
GO:0008253 Function 5'-nucleotidase activity IBA 21873635
GO:0016311 Process Dephosphorylation IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
621077 25717 ENSG00000168268
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9H857
Protein name 5'-nucleotidase domain-containing protein 2 (EC 3.1.3.-)
Protein function Promotes dephosphorylation of tyrosine 3-monooxygenase TH which decreases TH catalytic activity and leads to reduced synthesis of catecholamines including dopamine, noradrenaline and adrenaline. The exact mechanism of activity is unknown but may
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05761 5_nucleotid 56 → 497 Family
Sequence
Sequence length 520
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Show/Hide Text Mining Associations (9)
Associations from Text Mining
Disease Name Relationship Type References
Borderline Personality Disorder Associate 25612291
Breast Neoplasms Associate 36820551
Colitis Ulcerative Associate 39596612
Depressive Disorder Major Associate 25612291
Hepatoblastoma Associate 39684755
Lymphoma Large B Cell Diffuse Associate 35894142
Neoplasms Associate 35894142, 39684755
Pediatric Obesity Associate 25612291
Stomach Neoplasms Associate 37800836