PAPOLG (poly(A) polymerase gamma)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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64895 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Poly(A) polymerase gamma |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PAPOLG |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p16.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3` end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | Q9BWT3 | |||||||||||||||||||||||||
Protein name | Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) | |||||||||||||||||||||||||
Protein function | Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. {ECO:0000269|PubMed:1 | |||||||||||||||||||||||||
PDB | 4LT6 | |||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed predominantly in testis, and weakly in other tissues. Overexpressed in several tumors. {ECO:0000269|PubMed:11463842}. | |||||||||||||||||||||||||
Sequence | ||||||||||||||||||||||||||
Sequence length | 736 | |||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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