PCDH20 (protocadherin 20)

Gene

• Entrez ID: 64881
• Gene name: Protocadherin 20
• Gene symbol: PCDH20
• Synonyms (NCBI Gene): PCDH13
• Chromosome: 13
• Chromosome location: 13q21.2
• Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical c

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1216867	hsa-miR-3074-5p	CLIP-seq
MIRT1216868	hsa-miR-30a	CLIP-seq
MIRT1216869	hsa-miR-30b	CLIP-seq
MIRT1216870	hsa-miR-30c	CLIP-seq
MIRT1216871	hsa-miR-30d	CLIP-seq
MIRT1216872	hsa-miR-30e	CLIP-seq
MIRT1216873	hsa-miR-338-5p	CLIP-seq
MIRT1216874	hsa-miR-3607-3p	CLIP-seq
MIRT1216875	hsa-miR-4452	CLIP-seq
MIRT1216876	hsa-miR-4686	CLIP-seq
MIRT1216877	hsa-miR-4699-3p	CLIP-seq
MIRT1216878	hsa-miR-4705	CLIP-seq
MIRT1216879	hsa-miR-4760-3p	CLIP-seq
MIRT1216880	hsa-miR-486-5p	CLIP-seq
MIRT1216881	hsa-miR-552	CLIP-seq
MIRT2062579	hsa-let-7a	CLIP-seq
MIRT2062580	hsa-let-7b	CLIP-seq
MIRT2062581	hsa-let-7c	CLIP-seq
MIRT2062582	hsa-let-7d	CLIP-seq
MIRT2062583	hsa-let-7e	CLIP-seq
MIRT2062584	hsa-let-7f	CLIP-seq
MIRT2062585	hsa-let-7g	CLIP-seq
MIRT2062586	hsa-let-7i	CLIP-seq
MIRT2062587	hsa-miR-202	CLIP-seq
MIRT2062588	hsa-miR-4325	CLIP-seq
MIRT2062589	hsa-miR-4458	CLIP-seq
MIRT2062590	hsa-miR-4500	CLIP-seq
MIRT2062591	hsa-miR-4744	CLIP-seq
MIRT2062592	hsa-miR-543	CLIP-seq
MIRT2062593	hsa-miR-98	CLIP-seq
MIRT2062588	hsa-miR-4325	CLIP-seq
MIRT2062591	hsa-miR-4744	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0016020	Component	Membrane	IEA
GO:0050839	Function	Cell adhesion molecule binding	IBA

Other IDs

• MIM: 614449
• HGNC: 14257
• e!Ensembl: ENSG00000280165

Protein

• UniProt ID: Q8N6Y1
• Protein name: Protocadherin-20 (Protocadherin-13)
• Protein function: Potential calcium-dependent cell-adhesion protein.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00028	Cadherin	214 → 311	Cadherin domain	Domain
  PF00028	Cadherin	325 → 417	Cadherin domain	Domain
  PF00028	Cadherin	540 → 630	Cadherin domain	Domain
  PF00028	Cadherin	644 → 733	Cadherin domain	Domain
  PF00028	Cadherin	751 → 844	Cadherin domain	Domain

• Sequence:

  MRGRGNARSSQALGVSWCPATWHPRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLG
  SYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFS
  LASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLLL
  DVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVG
  INGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPL
  LGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYS
  QKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVI
  FRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPY
  KPYNNEYLLETTKPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLI
  ELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDRE
  EKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGV
  ISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEP
  ALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVI
  AYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVN
  LFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTLVALSVISLGS
  ITLVTGMGIYICLRKGEKHPREDENLEVQIPLKGKIDLHMRERKPMDISNI

• Sequence length: 951

Pathways

KEGG:

Virion - Lassa virus and SFTS virus