RFX7 (regulatory factor X7)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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64864 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Regulatory factor X7 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RFX7 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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MRD71, RFXDC2 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q2KHR2 | ||||||||||
| Protein name | DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2) | ||||||||||
| Protein function | Transcription factor (PubMed:29967452). Acts as a transcriptional activator by binding to promoter regions of target genes, such as PDCD4, PIK3IP1, MXD4, PNRC1, and RFX5 (PubMed:29967452, PubMed:34197623). Plays a role in natural killer (NK) cel | ||||||||||
| PDB | 4QQI , 6MEW | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed in many different tissue types including thymus and placenta, with high expression in brain (PubMed:18673564). Expressed in both inhibitory and excitatory neurons in cortex (PubMed:33658631). {ECO:0000269|PubMed:186735 | ||||||||||
| Sequence |
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| Sequence length | 1363 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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