RFX7 (regulatory factor X7)

Gene

• Entrez ID: 64864
• Gene name: Regulatory factor X7
• Gene symbol: RFX7
• Synonyms (NCBI Gene): MRD71, RFXDC2
• Chromosome: 15
• Chromosome location: 15q21.3
• Summary: RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023454	hsa-miR-30b-5p	Sequencing	20371350
MIRT029828	hsa-miR-26b-5p	Microarray	19088304
MIRT044661	hsa-miR-320a	CLASH	23622248
MIRT534723	hsa-miR-130a-3p	PAR-CLIP	22012620
MIRT534722	hsa-miR-130b-3p	PAR-CLIP	22012620
MIRT534721	hsa-miR-301b-3p	PAR-CLIP	22012620
MIRT534720	hsa-miR-4295	PAR-CLIP	22012620
MIRT534719	hsa-miR-301a-3p	PAR-CLIP	22012620
MIRT534718	hsa-miR-454-3p	PAR-CLIP	22012620
MIRT534717	hsa-miR-3666	PAR-CLIP	22012620
MIRT534716	hsa-miR-561-3p	PAR-CLIP	22012620
MIRT534715	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT534714	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT534713	hsa-miR-3135b	PAR-CLIP	22012620
MIRT534712	hsa-miR-1287-5p	PAR-CLIP	22012620
MIRT439778	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT439778	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT534723	hsa-miR-130a-3p	PAR-CLIP	22012620
MIRT534722	hsa-miR-130b-3p	PAR-CLIP	22012620
MIRT534721	hsa-miR-301b-3p	PAR-CLIP	22012620
MIRT534720	hsa-miR-4295	PAR-CLIP	22012620
MIRT534719	hsa-miR-301a-3p	PAR-CLIP	22012620
MIRT534718	hsa-miR-454-3p	PAR-CLIP	22012620
MIRT534717	hsa-miR-3666	PAR-CLIP	22012620
MIRT534716	hsa-miR-561-3p	PAR-CLIP	22012620
MIRT534715	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT534714	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT534713	hsa-miR-3135b	PAR-CLIP	22012620
MIRT534712	hsa-miR-1287-5p	PAR-CLIP	22012620
MIRT1302495	hsa-miR-105	CLIP-seq
MIRT1302496	hsa-miR-1183	CLIP-seq
MIRT1302497	hsa-miR-1237	CLIP-seq
MIRT1302498	hsa-miR-1245	CLIP-seq
MIRT1302499	hsa-miR-1248	CLIP-seq
MIRT1302500	hsa-miR-1251	CLIP-seq
MIRT1302501	hsa-miR-1273g	CLIP-seq
MIRT1302502	hsa-miR-1278	CLIP-seq
MIRT1302503	hsa-miR-1299	CLIP-seq
MIRT1302504	hsa-miR-137	CLIP-seq
MIRT1302505	hsa-miR-139-5p	CLIP-seq
MIRT1302506	hsa-miR-141	CLIP-seq
MIRT1302507	hsa-miR-142-5p	CLIP-seq
MIRT1302508	hsa-miR-148a	CLIP-seq
MIRT1302509	hsa-miR-148b	CLIP-seq
MIRT1302510	hsa-miR-152	CLIP-seq
MIRT1302511	hsa-miR-186	CLIP-seq
MIRT1302512	hsa-miR-200a	CLIP-seq
MIRT1302513	hsa-miR-204	CLIP-seq
MIRT1302514	hsa-miR-208a	CLIP-seq
MIRT1302515	hsa-miR-208b	CLIP-seq
MIRT1302516	hsa-miR-211	CLIP-seq
MIRT1302517	hsa-miR-2110	CLIP-seq
MIRT1302518	hsa-miR-224	CLIP-seq
MIRT1302519	hsa-miR-25	CLIP-seq
MIRT1302520	hsa-miR-29a	CLIP-seq
MIRT1302521	hsa-miR-29b	CLIP-seq
MIRT1302522	hsa-miR-29c	CLIP-seq
MIRT1302523	hsa-miR-3065-5p	CLIP-seq
MIRT1302524	hsa-miR-30a	CLIP-seq
MIRT1302525	hsa-miR-30b	CLIP-seq
MIRT1302526	hsa-miR-30c	CLIP-seq
MIRT1302527	hsa-miR-30d	CLIP-seq
MIRT1302528	hsa-miR-30e	CLIP-seq
MIRT1302529	hsa-miR-3120-3p	CLIP-seq
MIRT1302530	hsa-miR-3127-3p	CLIP-seq
MIRT1302531	hsa-miR-3129-3p	CLIP-seq
MIRT1302532	hsa-miR-3133	CLIP-seq
MIRT1302533	hsa-miR-32	CLIP-seq
MIRT1302534	hsa-miR-338-5p	CLIP-seq
MIRT1302535	hsa-miR-340	CLIP-seq
MIRT1302536	hsa-miR-3609	CLIP-seq
MIRT1302537	hsa-miR-3612	CLIP-seq
MIRT1302538	hsa-miR-3617	CLIP-seq
MIRT1302539	hsa-miR-3618	CLIP-seq
MIRT1302540	hsa-miR-3620	CLIP-seq
MIRT1302541	hsa-miR-363	CLIP-seq
MIRT1302542	hsa-miR-365	CLIP-seq
MIRT1302543	hsa-miR-3655	CLIP-seq
MIRT1302544	hsa-miR-3662	CLIP-seq
MIRT1302545	hsa-miR-367	CLIP-seq
MIRT1302546	hsa-miR-371b-5p	CLIP-seq
MIRT1302547	hsa-miR-3919	CLIP-seq
MIRT1302548	hsa-miR-3942-3p	CLIP-seq
MIRT1302549	hsa-miR-409-5p	CLIP-seq
MIRT1302550	hsa-miR-421	CLIP-seq
MIRT1302551	hsa-miR-4271	CLIP-seq
MIRT1302552	hsa-miR-4272	CLIP-seq
MIRT1302553	hsa-miR-4277	CLIP-seq
MIRT1302554	hsa-miR-4302	CLIP-seq
MIRT1302555	hsa-miR-4323	CLIP-seq
MIRT1302556	hsa-miR-4446-5p	CLIP-seq
MIRT1302557	hsa-miR-4474-3p	CLIP-seq
MIRT1302558	hsa-miR-4476	CLIP-seq
MIRT1302559	hsa-miR-4495	CLIP-seq
MIRT1302560	hsa-miR-4503	CLIP-seq
MIRT1302561	hsa-miR-450b-5p	CLIP-seq
MIRT1302562	hsa-miR-4635	CLIP-seq
MIRT1302563	hsa-miR-4659a-3p	CLIP-seq
MIRT1302564	hsa-miR-4659b-3p	CLIP-seq
MIRT1302565	hsa-miR-4666-3p	CLIP-seq
MIRT1302566	hsa-miR-4667-5p	CLIP-seq
MIRT1302567	hsa-miR-4697-3p	CLIP-seq
MIRT1302568	hsa-miR-4698	CLIP-seq
MIRT1302569	hsa-miR-4700-3p	CLIP-seq
MIRT1302570	hsa-miR-4700-5p	CLIP-seq
MIRT1302571	hsa-miR-4703-3p	CLIP-seq
MIRT1302572	hsa-miR-4719	CLIP-seq
MIRT1302573	hsa-miR-4725-3p	CLIP-seq
MIRT1302574	hsa-miR-4729	CLIP-seq
MIRT1302575	hsa-miR-4734	CLIP-seq
MIRT1302576	hsa-miR-4738-3p	CLIP-seq
MIRT1302577	hsa-miR-4753-3p	CLIP-seq
MIRT1302578	hsa-miR-4755-5p	CLIP-seq
MIRT1302579	hsa-miR-4756-3p	CLIP-seq
MIRT1302580	hsa-miR-4760-5p	CLIP-seq
MIRT1302581	hsa-miR-4778-3p	CLIP-seq
MIRT1302582	hsa-miR-4786-3p	CLIP-seq
MIRT1302583	hsa-miR-4797-5p	CLIP-seq
MIRT1302584	hsa-miR-4803	CLIP-seq
MIRT1302585	hsa-miR-488	CLIP-seq
MIRT1302586	hsa-miR-494	CLIP-seq
MIRT1302587	hsa-miR-499-5p	CLIP-seq
MIRT1302588	hsa-miR-507	CLIP-seq
MIRT1302589	hsa-miR-5095	CLIP-seq
MIRT1302590	hsa-miR-5096	CLIP-seq
MIRT1302591	hsa-miR-511	CLIP-seq
MIRT1302592	hsa-miR-520f	CLIP-seq
MIRT1302593	hsa-miR-545	CLIP-seq
MIRT1302594	hsa-miR-548a-5p	CLIP-seq
MIRT1302595	hsa-miR-548ab	CLIP-seq
MIRT1302596	hsa-miR-548ah	CLIP-seq
MIRT1302597	hsa-miR-548ak	CLIP-seq
MIRT1302598	hsa-miR-548b-5p	CLIP-seq
MIRT1302599	hsa-miR-548c-5p	CLIP-seq
MIRT1302600	hsa-miR-548d-5p	CLIP-seq
MIRT1302601	hsa-miR-548h	CLIP-seq
MIRT1302602	hsa-miR-548i	CLIP-seq
MIRT1302603	hsa-miR-548j	CLIP-seq
MIRT1302604	hsa-miR-548k	CLIP-seq
MIRT1302605	hsa-miR-548l	CLIP-seq
MIRT1302606	hsa-miR-548w	CLIP-seq
MIRT1302607	hsa-miR-548y	CLIP-seq
MIRT1302608	hsa-miR-557	CLIP-seq
MIRT1302609	hsa-miR-559	CLIP-seq
MIRT1302610	hsa-miR-578	CLIP-seq
MIRT1302611	hsa-miR-579	CLIP-seq
MIRT1302612	hsa-miR-582-5p	CLIP-seq
MIRT1302613	hsa-miR-606	CLIP-seq
MIRT1302614	hsa-miR-618	CLIP-seq
MIRT1302615	hsa-miR-623	CLIP-seq
MIRT1302616	hsa-miR-633	CLIP-seq
MIRT1302617	hsa-miR-641	CLIP-seq
MIRT1302618	hsa-miR-648	CLIP-seq
MIRT1302619	hsa-miR-650	CLIP-seq
MIRT1302620	hsa-miR-654-3p	CLIP-seq
MIRT1302621	hsa-miR-759	CLIP-seq
MIRT1302622	hsa-miR-767-5p	CLIP-seq
MIRT1302623	hsa-miR-875-3p	CLIP-seq
MIRT1302624	hsa-miR-885-5p	CLIP-seq
MIRT1302625	hsa-miR-92a	CLIP-seq
MIRT1302626	hsa-miR-92b	CLIP-seq
MIRT1302627	hsa-miR-934	CLIP-seq
MIRT1302628	hsa-miR-944	CLIP-seq
MIRT1553081	hsa-miR-4282	CLIP-seq
MIRT1302496	hsa-miR-1183	CLIP-seq
MIRT2089813	hsa-miR-1225-5p	CLIP-seq
MIRT1302499	hsa-miR-1248	CLIP-seq
MIRT2089814	hsa-miR-1273e	CLIP-seq
MIRT2089815	hsa-miR-130a	CLIP-seq
MIRT2089816	hsa-miR-130b	CLIP-seq
MIRT1302504	hsa-miR-137	CLIP-seq
MIRT1302505	hsa-miR-139-5p	CLIP-seq
MIRT2089817	hsa-miR-144	CLIP-seq
MIRT2089818	hsa-miR-147	CLIP-seq
MIRT2089819	hsa-miR-153	CLIP-seq
MIRT2089820	hsa-miR-1539	CLIP-seq
MIRT2089821	hsa-miR-1827	CLIP-seq
MIRT2089822	hsa-miR-199a-3p	CLIP-seq
MIRT2089823	hsa-miR-199b-3p	CLIP-seq
MIRT2089824	hsa-miR-2052	CLIP-seq
MIRT2089825	hsa-miR-2053	CLIP-seq
MIRT2089826	hsa-miR-2054	CLIP-seq
MIRT2089827	hsa-miR-210	CLIP-seq
MIRT2089828	hsa-miR-2113	CLIP-seq
MIRT1302519	hsa-miR-25	CLIP-seq
MIRT2089829	hsa-miR-301a	CLIP-seq
MIRT2089830	hsa-miR-301b	CLIP-seq
MIRT1302523	hsa-miR-3065-5p	CLIP-seq
MIRT2089831	hsa-miR-3074-5p	CLIP-seq
MIRT1302529	hsa-miR-3120-3p	CLIP-seq
MIRT2089832	hsa-miR-3121-5p	CLIP-seq
MIRT2089833	hsa-miR-3129-5p	CLIP-seq
MIRT2089834	hsa-miR-3182	CLIP-seq
MIRT2089835	hsa-miR-3185	CLIP-seq
MIRT1302533	hsa-miR-32	CLIP-seq
MIRT2089836	hsa-miR-323-3p	CLIP-seq
MIRT1302538	hsa-miR-3617	CLIP-seq
MIRT1302539	hsa-miR-3618	CLIP-seq
MIRT1302540	hsa-miR-3620	CLIP-seq
MIRT1302541	hsa-miR-363	CLIP-seq
MIRT2089837	hsa-miR-3650	CLIP-seq
MIRT2089838	hsa-miR-3653	CLIP-seq
MIRT1302543	hsa-miR-3655	CLIP-seq
MIRT2089839	hsa-miR-3658	CLIP-seq
MIRT1302545	hsa-miR-367	CLIP-seq
MIRT2089840	hsa-miR-3685	CLIP-seq
MIRT2089841	hsa-miR-370	CLIP-seq
MIRT2089842	hsa-miR-374a	CLIP-seq
MIRT2089843	hsa-miR-374b	CLIP-seq
MIRT2089844	hsa-miR-377	CLIP-seq
MIRT2089845	hsa-miR-384	CLIP-seq
MIRT2089846	hsa-miR-3920	CLIP-seq
MIRT1302548	hsa-miR-3942-3p	CLIP-seq
MIRT2089847	hsa-miR-3944-5p	CLIP-seq
MIRT2089848	hsa-miR-3977	CLIP-seq
MIRT1302552	hsa-miR-4272	CLIP-seq
MIRT2089849	hsa-miR-4291	CLIP-seq
MIRT2089850	hsa-miR-4433	CLIP-seq
MIRT2089851	hsa-miR-4459	CLIP-seq
MIRT2089852	hsa-miR-4473	CLIP-seq
MIRT2089853	hsa-miR-448	CLIP-seq
MIRT2089854	hsa-miR-4511	CLIP-seq
MIRT2089855	hsa-miR-454	CLIP-seq
MIRT2089856	hsa-miR-4649-3p	CLIP-seq
MIRT2089857	hsa-miR-4670-3p	CLIP-seq
MIRT2089858	hsa-miR-4699-3p	CLIP-seq
MIRT1302571	hsa-miR-4703-3p	CLIP-seq
MIRT2089859	hsa-miR-4718	CLIP-seq
MIRT1302572	hsa-miR-4719	CLIP-seq
MIRT2089860	hsa-miR-4724-5p	CLIP-seq
MIRT1302579	hsa-miR-4756-3p	CLIP-seq
MIRT2089861	hsa-miR-4762-3p	CLIP-seq
MIRT2089862	hsa-miR-4763-5p	CLIP-seq
MIRT2089863	hsa-miR-4768-3p	CLIP-seq
MIRT1302583	hsa-miR-4797-5p	CLIP-seq
MIRT1302586	hsa-miR-494	CLIP-seq
MIRT2089864	hsa-miR-498	CLIP-seq
MIRT2089865	hsa-miR-509-3p	CLIP-seq
MIRT1302590	hsa-miR-5096	CLIP-seq
MIRT2089866	hsa-miR-512-3p	CLIP-seq
MIRT1302592	hsa-miR-520f	CLIP-seq
MIRT2089867	hsa-miR-539	CLIP-seq
MIRT1302593	hsa-miR-545	CLIP-seq
MIRT2089868	hsa-miR-548b-3p	CLIP-seq
MIRT2089869	hsa-miR-550a	CLIP-seq
MIRT1302610	hsa-miR-578	CLIP-seq
MIRT1302611	hsa-miR-579	CLIP-seq
MIRT1302612	hsa-miR-582-5p	CLIP-seq
MIRT2089870	hsa-miR-587	CLIP-seq
MIRT2089871	hsa-miR-599	CLIP-seq
MIRT1302613	hsa-miR-606	CLIP-seq
MIRT1302617	hsa-miR-641	CLIP-seq
MIRT2089872	hsa-miR-656	CLIP-seq
MIRT1302621	hsa-miR-759	CLIP-seq
MIRT1302624	hsa-miR-885-5p	CLIP-seq
MIRT2089873	hsa-miR-889	CLIP-seq
MIRT2089874	hsa-miR-9	CLIP-seq
MIRT1302625	hsa-miR-92a	CLIP-seq
MIRT1302626	hsa-miR-92b	CLIP-seq
MIRT1302627	hsa-miR-934	CLIP-seq
MIRT1302628	hsa-miR-944	CLIP-seq
MIRT1302496	hsa-miR-1183	CLIP-seq
MIRT1302504	hsa-miR-137	CLIP-seq
MIRT1302506	hsa-miR-141	CLIP-seq
MIRT1302508	hsa-miR-148a	CLIP-seq
MIRT1302509	hsa-miR-148b	CLIP-seq
MIRT1302510	hsa-miR-152	CLIP-seq
MIRT1302512	hsa-miR-200a	CLIP-seq
MIRT2089826	hsa-miR-2054	CLIP-seq
MIRT1302514	hsa-miR-208a	CLIP-seq
MIRT1302515	hsa-miR-208b	CLIP-seq
MIRT2314688	hsa-miR-221	CLIP-seq
MIRT2314689	hsa-miR-222	CLIP-seq
MIRT1302519	hsa-miR-25	CLIP-seq
MIRT1302523	hsa-miR-3065-5p	CLIP-seq
MIRT2089831	hsa-miR-3074-5p	CLIP-seq
MIRT2314690	hsa-miR-3163	CLIP-seq
MIRT1302533	hsa-miR-32	CLIP-seq
MIRT1302534	hsa-miR-338-5p	CLIP-seq
MIRT1302537	hsa-miR-3612	CLIP-seq
MIRT1302538	hsa-miR-3617	CLIP-seq
MIRT1302541	hsa-miR-363	CLIP-seq
MIRT1302542	hsa-miR-365	CLIP-seq
MIRT1302544	hsa-miR-3662	CLIP-seq
MIRT1302545	hsa-miR-367	CLIP-seq
MIRT2089841	hsa-miR-370	CLIP-seq
MIRT1302548	hsa-miR-3942-3p	CLIP-seq
MIRT1302553	hsa-miR-4277	CLIP-seq
MIRT2314691	hsa-miR-4289	CLIP-seq
MIRT1302554	hsa-miR-4302	CLIP-seq
MIRT1302565	hsa-miR-4666-3p	CLIP-seq
MIRT1302567	hsa-miR-4697-3p	CLIP-seq
MIRT1302568	hsa-miR-4698	CLIP-seq
MIRT2089858	hsa-miR-4699-3p	CLIP-seq
MIRT2089859	hsa-miR-4718	CLIP-seq
MIRT1302574	hsa-miR-4729	CLIP-seq
MIRT1302580	hsa-miR-4760-5p	CLIP-seq
MIRT1302587	hsa-miR-499-5p	CLIP-seq
MIRT1302591	hsa-miR-511	CLIP-seq
MIRT1302592	hsa-miR-520f	CLIP-seq
MIRT2314692	hsa-miR-548v	CLIP-seq
MIRT1302617	hsa-miR-641	CLIP-seq
MIRT1302618	hsa-miR-648	CLIP-seq
MIRT1302619	hsa-miR-650	CLIP-seq
MIRT1302620	hsa-miR-654-3p	CLIP-seq
MIRT2314693	hsa-miR-668	CLIP-seq
MIRT1302624	hsa-miR-885-5p	CLIP-seq
MIRT1302625	hsa-miR-92a	CLIP-seq
MIRT1302626	hsa-miR-92b	CLIP-seq
MIRT1302628	hsa-miR-944	CLIP-seq
MIRT1302506	hsa-miR-141	CLIP-seq
MIRT1302512	hsa-miR-200a	CLIP-seq
MIRT1302517	hsa-miR-2110	CLIP-seq
MIRT1302523	hsa-miR-3065-5p	CLIP-seq
MIRT1302551	hsa-miR-4271	CLIP-seq
MIRT1302566	hsa-miR-4667-5p	CLIP-seq
MIRT2393661	hsa-miR-4694-3p	CLIP-seq
MIRT1302570	hsa-miR-4700-5p	CLIP-seq
MIRT1302573	hsa-miR-4725-3p	CLIP-seq
MIRT2393662	hsa-miR-4761-5p	CLIP-seq
MIRT2393663	hsa-miR-522	CLIP-seq
MIRT2393664	hsa-miR-548p	CLIP-seq
MIRT1302546	hsa-miR-371b-5p	CLIP-seq
MIRT1302548	hsa-miR-3942-3p	CLIP-seq
MIRT1302568	hsa-miR-4698	CLIP-seq
MIRT2439894	hsa-miR-4757-5p	CLIP-seq
MIRT1302621	hsa-miR-759	CLIP-seq
MIRT2611003	hsa-miR-1207-3p	CLIP-seq
MIRT2611004	hsa-miR-1257	CLIP-seq
MIRT2611005	hsa-miR-1287	CLIP-seq
MIRT2611006	hsa-miR-140-5p	CLIP-seq
MIRT1302506	hsa-miR-141	CLIP-seq
MIRT2611007	hsa-miR-194	CLIP-seq
MIRT1302512	hsa-miR-200a	CLIP-seq
MIRT2089826	hsa-miR-2054	CLIP-seq
MIRT2089828	hsa-miR-2113	CLIP-seq
MIRT2089831	hsa-miR-3074-5p	CLIP-seq
MIRT2611008	hsa-miR-3123	CLIP-seq
MIRT2611009	hsa-miR-3143	CLIP-seq
MIRT2611010	hsa-miR-369-5p	CLIP-seq
MIRT2089841	hsa-miR-370	CLIP-seq
MIRT2611011	hsa-miR-3941	CLIP-seq
MIRT2611012	hsa-miR-466	CLIP-seq
MIRT2611013	hsa-miR-4672	CLIP-seq
MIRT2611014	hsa-miR-4705	CLIP-seq
MIRT2089859	hsa-miR-4718	CLIP-seq
MIRT2611015	hsa-miR-4731-3p	CLIP-seq
MIRT2611016	hsa-miR-4801	CLIP-seq
MIRT2611017	hsa-miR-570	CLIP-seq
MIRT2611018	hsa-miR-643	CLIP-seq
MIRT2611019	hsa-miR-758	CLIP-seq
MIRT1302506	hsa-miR-141	CLIP-seq
MIRT1302512	hsa-miR-200a	CLIP-seq
MIRT2089826	hsa-miR-2054	CLIP-seq
MIRT2089828	hsa-miR-2113	CLIP-seq
MIRT2089831	hsa-miR-3074-5p	CLIP-seq
MIRT2611009	hsa-miR-3143	CLIP-seq
MIRT2089841	hsa-miR-370	CLIP-seq
MIRT2089859	hsa-miR-4718	CLIP-seq
MIRT2611017	hsa-miR-570	CLIP-seq
MIRT2611019	hsa-miR-758	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000979	Function	RNA polymerase II core promoter sequence-specific DNA binding	IDA	29967452
GO:0000979	Function	RNA polymerase II core promoter sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	25752541, 31864703, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	29967452
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 612660
• HGNC: 25777
• e!Ensembl: ENSG00000181827

Protein

• UniProt ID: Q2KHR2
• Protein name: DNA-binding protein RFX7 (Regulatory factor X 7) (Regulatory factor X domain-containing protein 2)
• Protein function: Transcription factor (PubMed:29967452). Acts as a transcriptional activator by binding to promoter regions of target genes, such as PDCD4, PIK3IP1, MXD4, PNRC1, and RFX5 (PubMed:29967452, PubMed:34197623). Plays a role in natural killer (NK) cel
• PDB: 4QQI, 6MEW
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02257	RFX_DNA_binding	8 → 86	RFX DNA-binding domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed in many different tissue types including thymus and placenta, with high expression in brain (PubMed:18673564). Expressed in both inhibitory and excitatory neurons in cortex (PubMed:33658631). {ECO:0000269|PubMed:186735
• Sequence:

  MSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADFGKIMKNV
  FPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTGDGLEGAEPSGQLQNIDEE
  VISSACRLVCEWAQKVLSQPFDTVLELARFLVKSHYIGTKSMAALTVMAAAPAGMKGITQ
  PSAFIPTAESNSFQPQVKTLPSPIDAKQQLQRKIQKKQQEQKLQSPLPGESAAKKSESAT
  SNGVTNLPNGNPSILSPQPIGIVVAAVPSPIPVQRTRQLVTSPSPMSSSDGKVLPLNVQV
  VTQHMQSVKQAPKTPQNVPASPGGDRSARHRYPQILPKPANTSALTIRSPTTVLFTSSPI
  KTAVVPASHMSSLNVVKMTTISLTPSNSNTPLKHSASVSSATGTTEESRSVPQIKNGSVV
  SLQSPGSRSSSAGGTSAVEVKVEPETSSDEHPVQCQENSDEAKAPQTPSALLGQKSNTDG
  ALQKPSNEGVIEIKATKVCDQRTKCKSRCNEMLPGTSTGNNQSTITLSVASQNLTFTSSS
  SPPNGDSINKDPKLCTKSPRKRLSSTLQETQVPPVKKPIVEQLSAATIEGQKQGSVKKDQ
  KVPHSGKTEGSTAGAQIPSKVSVNVSSHIGANQPLNSSALVISDSALEQQTTPSSSPDIK
  VKLEGSVFLLDSDSKSVGSFNPNGWQQITKDSEFISASCEQQQDISVMTIPEHSDINDLE
  KSVWELEGMPQDTYSQQLHSQIQESSLNQIQAHSSDQLPLQSELKEFEPSVSQTNESYFP
  FDDELTQDSIVEELVLMEQQMSMNNSHSYGNCLGMTLQSQSVTPGAPMSSHTSSTHFYHP
  IHSNGTPIHTPTPTPTPTPTPTPTPTPTSEMIAGSQSLSRESPCSRLAQTTPVDSALGSS
  RHTPIGTPHSNCSSSVPPSPVECRNPFAFTPISSSMAYHDASIVSSSPVKPMQRPMATHP
  DKTKLEWMNNGYSGVGNSSVSGHGILPSYQELVEDRFRKPHAFAVPGQSYQSQSRHHDTH
  FGRLTPVSPVQHQGATVNNTNKQEGFAVPAPLDNKGTNSSASSNFRCRSVSPAVHRQRNL
  SGSTLYPVSNIPRSNVTPFGSPVTPEVHVFTNVHTDACANNIAQRSQSVPLTVMMQTAFP
  NALQKQANSKKITNVLLSKLDSDNDDAVRGLGMNNLPSNYTARMNLTQILEPSTVFPSAN
  PQNMIDSSTSVYEFQTPSYLTKSNSTGQINFSPGDNQAQSEIGEQQLDFNSTVKDLLSGD
  SLQTNQQLVGQGASDLTNTASDFSSDIRLSSELSGSINDLNTLDPNLLFDPGRQQGQDDE
  ATLEELKNDPLFQQICSESMNSMTSSGFEWIESKDHPTVEMLG

• Sequence length: 1363

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Intellectual developmental disorder, autosomal dominant 71, with behavioral abnormalities	Likely pathogenic; Pathogenic	rs2504987146, rs2504987137, rs2504987254, rs750801787, rs749745135	RCV003223346 RCV003223354 RCV003223379 RCV003223380 RCV004820946
RFX7-related disorder	Likely pathogenic	rs2504989200	RCV003412317
See cases	Likely pathogenic; Pathogenic	rs2504987146	RCV003153252

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Lung cancer	Likely benign	rs117528481	RCV005929365
Microcephaly	Uncertain significance	rs2041652509	RCV001252942
Neurodevelopmental disorder	Conflicting classifications of pathogenicity	rs766009038	RCV001262652
Nonpapillary renal cell carcinoma	Likely benign	rs117528481	RCV005929361
Ovarian serous cystadenocarcinoma	Likely benign	rs117528481	RCV005929362
Thymoma	Likely benign	rs117528481	RCV005929363
Thyroid cancer, nonmedullary, 1	Likely benign	rs117528481	RCV005929364

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	28539126
Attention Deficit Disorder with Hyperactivity	Associate	33658631
Autism Spectrum Disorder	Associate	33658631
Breast Neoplasms	Associate	20946665
Disease	Associate	33658631
Intellectual Disability	Associate	33658631
Sleep Wake Disorders	Associate	33658631
Stomach Neoplasms	Associate	36045400