ETNPPL (ethanolamine-phosphate phospho-lyase)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64850
Gene name Gene Name - the full gene name approved by the HGNC.
Ethanolamine-phosphate phospho-lyase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ETNPPL
Synonyms (NCBI Gene) Gene synonyms aliases
AGXT2L1
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q25
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT022622 hsa-miR-124-3p Microarray 18668037
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0005575 Component Cellular_component ND
GO:0005759 Component Mitochondrial matrix TAS
GO:0006646 Process Phosphatidylethanolamine biosynthetic process TAS
GO:0008483 Function Transaminase activity IEA
GO:0030170 Function Pyridoxal phosphate binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
614682 14404 ENSG00000164089
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q8TBG4
Protein name Ethanolamine-phosphate phospho-lyase (EC 4.2.3.2) (Alanine--glyoxylate aminotransferase 2-like 1)
Protein function Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
PDB 6TOR
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00202 Aminotran_3 26 → 433 Aminotransferase class-III Domain
Sequence
Sequence length 499
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG   Reactome
  Glycerophospholipid metabolism
Metabolic pathways 		  Synthesis of PE
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)		 18191109, 22241472
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Glioblastoma Glioblastoma CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 GWAS, CBGDA
Show/Hide Text Mining Associations (16)
Associations from Text Mining
Disease Name Relationship Type References
Bipolar Disorder Associate 18191109
Carcinoma Hepatocellular Inhibit 37637156
Carcinoma Hepatocellular Associate 40154596
Cerebral Infarction Associate 26352407
Glioblastoma Associate 32647207
Glioma Inhibit 32218467
Liver Diseases Associate 40154596
Mental Disorders Associate 23761375
Mitochondrial Diseases Associate 40154596
Neoplasm Metastasis Associate 37637156