ST3GAL2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2)

Gene

• Entrez ID: 6483
• Gene name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2
• Gene symbol: ST3GAL2
• Synonyms (NCBI Gene): Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2
• Chromosome: 16
• Chromosome location: 16q22.1
• Summary: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT042983	hsa-miR-324-3p	CLASH	23622248
MIRT042983	hsa-miR-324-3p	CLASH	23622248
MIRT042249	hsa-miR-484	CLASH	23622248
MIRT039844	hsa-miR-615-3p	CLASH	23622248
MIRT039844	hsa-miR-615-3p	CLASH	23622248
MIRT036742	hsa-miR-760	CLASH	23622248
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677069	hsa-miR-5693	HITS-CLIP	23824327
MIRT677068	hsa-miR-5193	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677067	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT677066	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT677065	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT677064	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT677063	hsa-miR-5698	HITS-CLIP	23824327
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT439533	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439533	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677069	hsa-miR-5693	HITS-CLIP	23824327
MIRT677068	hsa-miR-5193	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677067	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT677066	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT677065	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT677064	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT677063	hsa-miR-5698	HITS-CLIP	23824327
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT635490	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635489	hsa-miR-1281	HITS-CLIP	23824327
MIRT635488	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT635487	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635486	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT635485	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT635484	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635483	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635482	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635481	hsa-miR-4284	HITS-CLIP	23824327
MIRT1393428	hsa-miR-103b	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT1393430	hsa-miR-1236	CLIP-seq
MIRT1393431	hsa-miR-1252	CLIP-seq
MIRT1393432	hsa-miR-1253	CLIP-seq
MIRT1393433	hsa-miR-1254	CLIP-seq
MIRT1393434	hsa-miR-1271	CLIP-seq
MIRT1393435	hsa-miR-1279	CLIP-seq
MIRT1393436	hsa-miR-1287	CLIP-seq
MIRT1393437	hsa-miR-129-5p	CLIP-seq
MIRT1393438	hsa-miR-149	CLIP-seq
MIRT1393439	hsa-miR-182	CLIP-seq
MIRT1393440	hsa-miR-1827	CLIP-seq
MIRT1393441	hsa-miR-1908	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT1393443	hsa-miR-197	CLIP-seq
MIRT1393444	hsa-miR-200b	CLIP-seq
MIRT1393445	hsa-miR-200c	CLIP-seq
MIRT1393446	hsa-miR-22	CLIP-seq
MIRT1393447	hsa-miR-2392	CLIP-seq
MIRT1393448	hsa-miR-25	CLIP-seq
MIRT1393449	hsa-miR-298	CLIP-seq
MIRT1393450	hsa-miR-302f	CLIP-seq
MIRT1393451	hsa-miR-3064-5p	CLIP-seq
MIRT1393452	hsa-miR-3116	CLIP-seq
MIRT1393453	hsa-miR-3126-3p	CLIP-seq
MIRT1393454	hsa-miR-3140-3p	CLIP-seq
MIRT1393455	hsa-miR-3153	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393457	hsa-miR-32	CLIP-seq
MIRT1393458	hsa-miR-323-5p	CLIP-seq
MIRT1393459	hsa-miR-33a	CLIP-seq
MIRT1393460	hsa-miR-33b	CLIP-seq
MIRT1393461	hsa-miR-3529	CLIP-seq
MIRT1393462	hsa-miR-3612	CLIP-seq
MIRT1393463	hsa-miR-3616-3p	CLIP-seq
MIRT1393464	hsa-miR-3621	CLIP-seq
MIRT1393465	hsa-miR-363	CLIP-seq
MIRT1393466	hsa-miR-3649	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393468	hsa-miR-3656	CLIP-seq
MIRT1393469	hsa-miR-367	CLIP-seq
MIRT1393470	hsa-miR-3672	CLIP-seq
MIRT1393471	hsa-miR-3678-3p	CLIP-seq
MIRT1393472	hsa-miR-375	CLIP-seq
MIRT1393473	hsa-miR-379	CLIP-seq
MIRT1393474	hsa-miR-3937	CLIP-seq
MIRT1393475	hsa-miR-3942-3p	CLIP-seq
MIRT1393476	hsa-miR-4251	CLIP-seq
MIRT1393477	hsa-miR-429	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT1393479	hsa-miR-4326	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393481	hsa-miR-4443	CLIP-seq
MIRT1393482	hsa-miR-4451	CLIP-seq
MIRT1393483	hsa-miR-4456	CLIP-seq
MIRT1393484	hsa-miR-4505	CLIP-seq
MIRT1393485	hsa-miR-452	CLIP-seq
MIRT1393486	hsa-miR-4641	CLIP-seq
MIRT1393487	hsa-miR-4642	CLIP-seq
MIRT1393488	hsa-miR-4650-3p	CLIP-seq
MIRT1393489	hsa-miR-4676-3p	CLIP-seq
MIRT1393490	hsa-miR-4676-5p	CLIP-seq
MIRT1393491	hsa-miR-4706	CLIP-seq
MIRT1393492	hsa-miR-4728-5p	CLIP-seq
MIRT1393493	hsa-miR-4731-5p	CLIP-seq
MIRT1393494	hsa-miR-4734	CLIP-seq
MIRT1393495	hsa-miR-4735-5p	CLIP-seq
MIRT1393496	hsa-miR-4749-5p	CLIP-seq
MIRT1393497	hsa-miR-4759	CLIP-seq
MIRT1393498	hsa-miR-4760-3p	CLIP-seq
MIRT1393499	hsa-miR-4775	CLIP-seq
MIRT1393500	hsa-miR-4778-5p	CLIP-seq
MIRT1393501	hsa-miR-4794	CLIP-seq
MIRT1393502	hsa-miR-5096	CLIP-seq
MIRT1393503	hsa-miR-575	CLIP-seq
MIRT1393504	hsa-miR-590-3p	CLIP-seq
MIRT1393505	hsa-miR-604	CLIP-seq
MIRT1393506	hsa-miR-650	CLIP-seq
MIRT1393507	hsa-miR-661	CLIP-seq
MIRT1393508	hsa-miR-663	CLIP-seq
MIRT1393509	hsa-miR-665	CLIP-seq
MIRT1393510	hsa-miR-767-3p	CLIP-seq
MIRT1393511	hsa-miR-876-3p	CLIP-seq
MIRT1393512	hsa-miR-887	CLIP-seq
MIRT1393513	hsa-miR-92a	CLIP-seq
MIRT1393514	hsa-miR-92b	CLIP-seq
MIRT1393515	hsa-miR-940	CLIP-seq
MIRT1393516	hsa-miR-96	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118090	hsa-miR-1208	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT1393433	hsa-miR-1254	CLIP-seq
MIRT1393437	hsa-miR-129-5p	CLIP-seq
MIRT2118092	hsa-miR-1307	CLIP-seq
MIRT2118093	hsa-miR-138	CLIP-seq
MIRT2118094	hsa-miR-140-5p	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT2118095	hsa-miR-1976	CLIP-seq
MIRT2118096	hsa-miR-2110	CLIP-seq
MIRT1393446	hsa-miR-22	CLIP-seq
MIRT2118097	hsa-miR-27a	CLIP-seq
MIRT2118098	hsa-miR-27b	CLIP-seq
MIRT1393452	hsa-miR-3116	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT2118100	hsa-miR-3147	CLIP-seq
MIRT2118101	hsa-miR-3149	CLIP-seq
MIRT2118102	hsa-miR-3150a-3p	CLIP-seq
MIRT2118103	hsa-miR-3175	CLIP-seq
MIRT2118104	hsa-miR-3192	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393458	hsa-miR-323-5p	CLIP-seq
MIRT2118105	hsa-miR-3545-5p	CLIP-seq
MIRT2118106	hsa-miR-3614-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393470	hsa-miR-3672	CLIP-seq
MIRT2118107	hsa-miR-3679-3p	CLIP-seq
MIRT2118108	hsa-miR-3691-3p	CLIP-seq
MIRT2118109	hsa-miR-4279	CLIP-seq
MIRT2118110	hsa-miR-4283	CLIP-seq
MIRT2118111	hsa-miR-4297	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT2118112	hsa-miR-4320	CLIP-seq
MIRT2118113	hsa-miR-4425	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393483	hsa-miR-4456	CLIP-seq
MIRT2118114	hsa-miR-4460	CLIP-seq
MIRT1393484	hsa-miR-4505	CLIP-seq
MIRT2118115	hsa-miR-4667-3p	CLIP-seq
MIRT2118116	hsa-miR-4691-5p	CLIP-seq
MIRT2118117	hsa-miR-4722-3p	CLIP-seq
MIRT2118118	hsa-miR-4727-3p	CLIP-seq
MIRT1393492	hsa-miR-4728-5p	CLIP-seq
MIRT1393495	hsa-miR-4735-5p	CLIP-seq
MIRT1393499	hsa-miR-4775	CLIP-seq
MIRT1393501	hsa-miR-4794	CLIP-seq
MIRT2118119	hsa-miR-509-3p	CLIP-seq
MIRT2118120	hsa-miR-5095	CLIP-seq
MIRT2118121	hsa-miR-513a-5p	CLIP-seq
MIRT2118122	hsa-miR-552	CLIP-seq
MIRT2118123	hsa-miR-562	CLIP-seq
MIRT1393504	hsa-miR-590-3p	CLIP-seq
MIRT2118124	hsa-miR-647	CLIP-seq
MIRT1393507	hsa-miR-661	CLIP-seq
MIRT2118125	hsa-miR-873	CLIP-seq
MIRT1393511	hsa-miR-876-3p	CLIP-seq
MIRT2118126	hsa-miR-939	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT2340049	hsa-miR-1238	CLIP-seq
MIRT2340050	hsa-miR-1275	CLIP-seq
MIRT1393435	hsa-miR-1279	CLIP-seq
MIRT1393437	hsa-miR-129-5p	CLIP-seq
MIRT2118092	hsa-miR-1307	CLIP-seq
MIRT2118094	hsa-miR-140-5p	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT1393443	hsa-miR-197	CLIP-seq
MIRT2118097	hsa-miR-27a	CLIP-seq
MIRT2118098	hsa-miR-27b	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT2340051	hsa-miR-339-5p	CLIP-seq
MIRT1393461	hsa-miR-3529	CLIP-seq
MIRT2118106	hsa-miR-3614-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393470	hsa-miR-3672	CLIP-seq
MIRT1393473	hsa-miR-379	CLIP-seq
MIRT2340052	hsa-miR-3929	CLIP-seq
MIRT2118109	hsa-miR-4279	CLIP-seq
MIRT2118111	hsa-miR-4297	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT2340053	hsa-miR-4419b	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT2340054	hsa-miR-4447	CLIP-seq
MIRT1393482	hsa-miR-4451	CLIP-seq
MIRT2340055	hsa-miR-4472	CLIP-seq
MIRT2340056	hsa-miR-4478	CLIP-seq
MIRT2340057	hsa-miR-4525	CLIP-seq
MIRT1393488	hsa-miR-4650-3p	CLIP-seq
MIRT2340058	hsa-miR-4665-5p	CLIP-seq
MIRT2340059	hsa-miR-4723-5p	CLIP-seq
MIRT1393492	hsa-miR-4728-5p	CLIP-seq
MIRT2340060	hsa-miR-4804-3p	CLIP-seq
MIRT2118120	hsa-miR-5095	CLIP-seq
MIRT1393502	hsa-miR-5096	CLIP-seq
MIRT2118121	hsa-miR-513a-5p	CLIP-seq
MIRT2340061	hsa-miR-516a-3p	CLIP-seq
MIRT2340062	hsa-miR-548ad	CLIP-seq
MIRT2118122	hsa-miR-552	CLIP-seq
MIRT2340063	hsa-miR-553	CLIP-seq
MIRT2340064	hsa-miR-625	CLIP-seq
MIRT2340065	hsa-miR-764	CLIP-seq
MIRT2340066	hsa-miR-933	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT2395235	hsa-miR-1273f	CLIP-seq
MIRT2118092	hsa-miR-1307	CLIP-seq
MIRT2118093	hsa-miR-138	CLIP-seq
MIRT2395236	hsa-miR-143	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT2118106	hsa-miR-3614-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT2118108	hsa-miR-3691-3p	CLIP-seq
MIRT2118111	hsa-miR-4297	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT2395237	hsa-miR-4708-5p	CLIP-seq
MIRT1393494	hsa-miR-4734	CLIP-seq
MIRT2395238	hsa-miR-4770	CLIP-seq
MIRT2118120	hsa-miR-5095	CLIP-seq
MIRT2118122	hsa-miR-552	CLIP-seq
MIRT2118123	hsa-miR-562	CLIP-seq
MIRT2340065	hsa-miR-764	CLIP-seq
MIRT2118125	hsa-miR-873	CLIP-seq
MIRT2340066	hsa-miR-933	CLIP-seq
MIRT2433609	hsa-miR-1538	CLIP-seq
MIRT2433610	hsa-miR-4707-3p	CLIP-seq
MIRT2433611	hsa-miR-4745-3p	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT2118092	hsa-miR-1307	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT2118101	hsa-miR-3149	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393495	hsa-miR-4735-5p	CLIP-seq
MIRT1393499	hsa-miR-4775	CLIP-seq
MIRT1393501	hsa-miR-4794	CLIP-seq
MIRT1393504	hsa-miR-590-3p	CLIP-seq
MIRT1393429	hsa-miR-1182	CLIP-seq
MIRT2118091	hsa-miR-122	CLIP-seq
MIRT2118092	hsa-miR-1307	CLIP-seq
MIRT1393442	hsa-miR-193a-5p	CLIP-seq
MIRT2118099	hsa-miR-3135b	CLIP-seq
MIRT2118101	hsa-miR-3149	CLIP-seq
MIRT1393456	hsa-miR-3194-3p	CLIP-seq
MIRT1393467	hsa-miR-3652	CLIP-seq
MIRT1393478	hsa-miR-431	CLIP-seq
MIRT1393480	hsa-miR-4430	CLIP-seq
MIRT1393495	hsa-miR-4735-5p	CLIP-seq
MIRT1393499	hsa-miR-4775	CLIP-seq
MIRT1393501	hsa-miR-4794	CLIP-seq
MIRT1393504	hsa-miR-590-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	25916169
GO:0000139	Component	Golgi membrane	TAS
GO:0003836	Function	Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IBA
GO:0003836	Function	Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IDA	8920913, 9266697, 12716912, 25916169
GO:0003836	Function	Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IEA
GO:0003836	Function	Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	TAS
GO:0005576	Component	Extracellular region	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IBA
GO:0006486	Process	Protein glycosylation	IDA	9266697
GO:0006486	Process	Protein glycosylation	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006688	Process	Glycosphingolipid biosynthetic process	TAS
GO:0008373	Function	Sialyltransferase activity	IEA
GO:0008373	Function	Sialyltransferase activity	TAS
GO:0009101	Process	Glycoprotein biosynthetic process	IDA	9266697
GO:0009247	Process	Glycolipid biosynthetic process	IDA	9266697
GO:0009312	Process	Oligosaccharide biosynthetic process	IDA	9266697
GO:0010706	Process	Ganglioside biosynthetic process via lactosylceramide	IBA
GO:0010706	Process	Ganglioside biosynthetic process via lactosylceramide	IDA	8920913
GO:0010706	Process	Ganglioside biosynthetic process via lactosylceramide	IEA
GO:0010707	Process	Globoside biosynthetic process via lactosylceramide	IDA	12716912
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0018146	Process	Keratan sulfate proteoglycan biosynthetic process	TAS
GO:0019082	Process	Viral protein processing	TAS
GO:0032580	Component	Golgi cisterna membrane	IEA
GO:0042803	Function	Protein homodimerization activity	IDA	25916169
GO:0047288	Function	Beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase	IEA
GO:0097503	Process	Sialylation	IBA
GO:0097503	Process	Sialylation	IDA	9266697

Other IDs

• MIM: 607188
• HGNC: 10863
• e!Ensembl: ENSG00000157350

Protein

• UniProt ID: Q16842
• Protein name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (EC 2.4.3.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (Monosialoganglioside sialyltransferase)
• Protein function: A beta-galactoside alpha2-3 sialyltransferase primarily involved in terminal sialylation of ganglio and globo series glycolipids (PubMed:8920913, PubMed:9266697). Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00777	Glyco_transf_29	94 → 348	Glycosyltransferase family 29 (sialyltransferase)	Family

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. {ECO:0000269|PubMed:8920913, ECO:0000269|PubMed:9266697}.
• Sequence:

  MKCSLRVWFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRL
  SKERLSGKSCACRRCMGDAGASDWFDSHFDGNISPVWTRENMDLPPDVQRWWMMLQPQFK
  SHNTNEVLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMN
  QAPTVGFEQDVGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTY
  APVKSFLRVDKEKVQIYNPAFFKYIHDRWTEHHGRYPSTGMLVLFFALHVCDEVNVYGFG
  ADSRGNWHHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYRGN

• Sequence length: 350

Pathways

KEGG:

Mucin type O-glycan biosynthesis
Glycosaminoglycan biosynthesis - keratan sulfate
Glycosphingolipid biosynthesis - globo and isoglobo series
Glycosphingolipid biosynthesis - ganglio series
Metabolic pathways

Reactome:

Keratan sulfate biosynthesis
Sialic acid metabolism
Termination of O-glycan biosynthesis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Diabetes Mellitus	Associate	36790478	★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Associate	25359423	★☆☆☆☆ Found in Text Mining only
Mandibular Nerve Injuries	Associate	27845370	★☆☆☆☆ Found in Text Mining only
Meningioma	Associate	34943806	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	23479608	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Associate	29902255	★☆☆☆☆ Found in Text Mining only