Gene Gene information from NCBI Gene database.
Entrez ID 648
Gene name BMI1 proto-oncogene, polycomb ring finger
Gene symbol BMI1
Synonyms (NCBI Gene)
FLVI2/BMI1PCGF4RNF51flvi-2/bmi-1
Chromosome 10
Chromosome location 10p12.2
Summary This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development
miRNA miRNA information provided by mirtarbase database.
595
miRTarBase ID miRNA Experiments Reference
MIRT000197 hsa-miR-200c-3p Review 20026422
MIRT004645 hsa-miR-128-3p Review 20029422
MIRT004645 hsa-miR-128-3p ImmunohistochemistryIn situ hybridizationMicroarrayqRT-PCRWestern blot 19010882
MIRT000197 hsa-miR-200c-3p Luciferase reporter assayWestern blot 19665978
MIRT000197 hsa-miR-200c-3p Luciferase reporter assayWestern blot 19665978
Transcription factors Transcription factors information provided by TRRUST V2 database.
4
Transcription factor Regulation Reference
E2F1 Unknown 17360938
MYC Activation 21856782
MYCN Activation 21856782
TWIST1 Activation 21876555
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
54
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IMP 19636380
GO:0000151 Component Ubiquitin ligase complex IDA 16714294
GO:0000792 Component Heterochromatin IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
164831 1066 ENSG00000168283
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Polycomb repressive complex
Signaling pathways regulating pluripotency of stem cells
Transcriptional misregulation in cancer
MicroRNAs in cancer
  Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6