Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	64777
Gene name	Required for meiotic nuclear division 5 homolog B
Gene symbol	RMND5B
Synonyms (NCBI Gene)	GID2GID2B
Chromosome	5
Chromosome location	5q35.3

Show/Hide all (85)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048892	hsa-miR-93-5p	CLASH	23622248
MIRT1308553	hsa-miR-1179	CLIP-seq
MIRT1308554	hsa-miR-1207-5p	CLIP-seq
MIRT1308555	hsa-miR-1265	CLIP-seq
MIRT1308556	hsa-miR-140-3p	CLIP-seq
MIRT1308557	hsa-miR-1909	CLIP-seq
MIRT1308558	hsa-miR-3138	CLIP-seq
MIRT1308559	hsa-miR-3190	CLIP-seq
MIRT1308560	hsa-miR-3202	CLIP-seq
MIRT1308561	hsa-miR-338-3p	CLIP-seq
MIRT1308562	hsa-miR-3616-3p	CLIP-seq
MIRT1308563	hsa-miR-3622b-5p	CLIP-seq
MIRT1308564	hsa-miR-4436b-3p	CLIP-seq
MIRT1308565	hsa-miR-451b	CLIP-seq
MIRT1308566	hsa-miR-4533	CLIP-seq
MIRT1308567	hsa-miR-455-3p	CLIP-seq
MIRT1308568	hsa-miR-4642	CLIP-seq
MIRT1308569	hsa-miR-4651	CLIP-seq
MIRT1308570	hsa-miR-4670-3p	CLIP-seq
MIRT1308571	hsa-miR-4721	CLIP-seq
MIRT1308572	hsa-miR-4722-5p	CLIP-seq
MIRT1308573	hsa-miR-4763-3p	CLIP-seq
MIRT1308574	hsa-miR-608	CLIP-seq
MIRT1308575	hsa-miR-647	CLIP-seq
MIRT1308576	hsa-miR-885-3p	CLIP-seq
MIRT2091555	hsa-miR-605	CLIP-seq
MIRT2316150	hsa-miR-214	CLIP-seq
MIRT2316151	hsa-miR-3184	CLIP-seq
MIRT1308561	hsa-miR-338-3p	CLIP-seq
MIRT2316152	hsa-miR-3619-5p	CLIP-seq
MIRT2316153	hsa-miR-423-5p	CLIP-seq
MIRT2316154	hsa-miR-4287	CLIP-seq
MIRT2316155	hsa-miR-4469	CLIP-seq
MIRT1308565	hsa-miR-451b	CLIP-seq
MIRT2316156	hsa-miR-4523	CLIP-seq
MIRT2316157	hsa-miR-4685-3p	CLIP-seq
MIRT2316158	hsa-miR-4688	CLIP-seq
MIRT1308572	hsa-miR-4722-5p	CLIP-seq
MIRT2316159	hsa-miR-761	CLIP-seq
MIRT2612203	hsa-miR-125a-3p	CLIP-seq
MIRT2612204	hsa-miR-1305	CLIP-seq
MIRT1308556	hsa-miR-140-3p	CLIP-seq
MIRT2612205	hsa-miR-204	CLIP-seq
MIRT2612206	hsa-miR-211	CLIP-seq
MIRT2316150	hsa-miR-214	CLIP-seq
MIRT2612207	hsa-miR-3065-5p	CLIP-seq
MIRT2612208	hsa-miR-3124-3p	CLIP-seq
MIRT2612209	hsa-miR-3162-3p	CLIP-seq
MIRT1308561	hsa-miR-338-3p	CLIP-seq
MIRT2316152	hsa-miR-3619-5p	CLIP-seq
MIRT2612210	hsa-miR-421	CLIP-seq
MIRT2612211	hsa-miR-4284	CLIP-seq
MIRT2316154	hsa-miR-4287	CLIP-seq
MIRT2316155	hsa-miR-4469	CLIP-seq
MIRT2316156	hsa-miR-4523	CLIP-seq
MIRT1308567	hsa-miR-455-3p	CLIP-seq
MIRT2612212	hsa-miR-4633-5p	CLIP-seq
MIRT2612213	hsa-miR-4659a-5p	CLIP-seq
MIRT2612214	hsa-miR-4659b-5p	CLIP-seq
MIRT1308570	hsa-miR-4670-3p	CLIP-seq
MIRT2316157	hsa-miR-4685-3p	CLIP-seq
MIRT1308572	hsa-miR-4722-5p	CLIP-seq
MIRT2612215	hsa-miR-4755-3p	CLIP-seq
MIRT2612216	hsa-miR-513a-5p	CLIP-seq
MIRT2612217	hsa-miR-552	CLIP-seq
MIRT2612218	hsa-miR-570	CLIP-seq
MIRT2316159	hsa-miR-761	CLIP-seq
MIRT2612219	hsa-miR-764	CLIP-seq
MIRT1308556	hsa-miR-140-3p	CLIP-seq
MIRT2612205	hsa-miR-204	CLIP-seq
MIRT2612206	hsa-miR-211	CLIP-seq
MIRT2316150	hsa-miR-214	CLIP-seq
MIRT2612208	hsa-miR-3124-3p	CLIP-seq
MIRT1308561	hsa-miR-338-3p	CLIP-seq
MIRT2316152	hsa-miR-3619-5p	CLIP-seq
MIRT2316154	hsa-miR-4287	CLIP-seq
MIRT2316155	hsa-miR-4469	CLIP-seq
MIRT1308567	hsa-miR-455-3p	CLIP-seq
MIRT2612212	hsa-miR-4633-5p	CLIP-seq
MIRT2612213	hsa-miR-4659a-5p	CLIP-seq
MIRT2612214	hsa-miR-4659b-5p	CLIP-seq
MIRT1308570	hsa-miR-4670-3p	CLIP-seq
MIRT2316157	hsa-miR-4685-3p	CLIP-seq
MIRT1308572	hsa-miR-4722-5p	CLIP-seq
MIRT2316159	hsa-miR-761	CLIP-seq

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004842	Function	Ubiquitin-protein transferase activity	IBA
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	25793641
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0008270	Function	Zinc ion binding	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0034657	Component	GID complex	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q96G75

Protein name

E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B)

Protein function

Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required f

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10607	CLTH	155 → 299	CTLH/CRA C-terminal to LisH motif domain	Domain

Sequence

MEQCACVERELDKVLQKFLTYGQHCERSLEELLHYVGQLRAELASAALQGTPLSATLSLV
MSQCCRKIKDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDAREQQQQIL
QMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVS
HRQRLLELNSSLEFKLHRLHFIRLLAGGPAKQLEALSYARHFQPFARLHQREIQVMMGSL
VYLRLGLEKSPYCHLLDSSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMN
IKAVIEQRQCTGVWNHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVI
SRDALNKLINGGKLKCPYCPMEQNPADGKRIIF

Sequence length

393

Interactions

View interactions

RMND5B (required for meiotic nuclear division 5 homolog B)