CCDC136 (coiled-coil domain containing 136)

Gene

• Entrez ID: 64753
• Gene name: Coiled-coil domain containing 136
• Gene symbol: CCDC136
• Synonyms (NCBI Gene): NAG6
• Chromosome: 7
• Chromosome location: 7q32.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT041851	hsa-miR-484	CLASH	23622248
MIRT868037	hsa-miR-2116	CLIP-seq
MIRT868038	hsa-miR-3144-5p	CLIP-seq
MIRT868039	hsa-miR-3191	CLIP-seq
MIRT868040	hsa-miR-3675-5p	CLIP-seq
MIRT868041	hsa-miR-3714	CLIP-seq
MIRT868042	hsa-miR-3941	CLIP-seq
MIRT868043	hsa-miR-4457	CLIP-seq
MIRT868044	hsa-miR-4643	CLIP-seq
MIRT868045	hsa-miR-4652-5p	CLIP-seq
MIRT868046	hsa-miR-466	CLIP-seq
MIRT868047	hsa-miR-4662a-5p	CLIP-seq
MIRT868048	hsa-miR-4672	CLIP-seq
MIRT868049	hsa-miR-4717-3p	CLIP-seq
MIRT868050	hsa-miR-4731-3p	CLIP-seq
MIRT868051	hsa-miR-4797-5p	CLIP-seq
MIRT868052	hsa-miR-4801	CLIP-seq
MIRT868053	hsa-miR-4802-3p	CLIP-seq
MIRT868054	hsa-miR-510	CLIP-seq
MIRT868055	hsa-miR-600	CLIP-seq
MIRT868056	hsa-miR-642b	CLIP-seq
MIRT868057	hsa-miR-940	CLIP-seq
MIRT2497927	hsa-miR-1225-5p	CLIP-seq
MIRT2497928	hsa-miR-1273f	CLIP-seq
MIRT2497929	hsa-miR-128	CLIP-seq
MIRT2497930	hsa-miR-1293	CLIP-seq
MIRT2497931	hsa-miR-1913	CLIP-seq
MIRT2497932	hsa-miR-1976	CLIP-seq
MIRT2497933	hsa-miR-2467-5p	CLIP-seq
MIRT2497934	hsa-miR-3128	CLIP-seq
MIRT868038	hsa-miR-3144-5p	CLIP-seq
MIRT2497935	hsa-miR-3147	CLIP-seq
MIRT2497936	hsa-miR-3150a-3p	CLIP-seq
MIRT2497937	hsa-miR-3150b-3p	CLIP-seq
MIRT2497938	hsa-miR-3175	CLIP-seq
MIRT2497939	hsa-miR-3188	CLIP-seq
MIRT868039	hsa-miR-3191	CLIP-seq
MIRT2497940	hsa-miR-320a	CLIP-seq
MIRT2497941	hsa-miR-320b	CLIP-seq
MIRT2497942	hsa-miR-320c	CLIP-seq
MIRT2497943	hsa-miR-320d	CLIP-seq
MIRT2497944	hsa-miR-324-3p	CLIP-seq
MIRT2497945	hsa-miR-346	CLIP-seq
MIRT2497946	hsa-miR-3657	CLIP-seq
MIRT868040	hsa-miR-3675-5p	CLIP-seq
MIRT2497947	hsa-miR-370	CLIP-seq
MIRT2497948	hsa-miR-3926	CLIP-seq
MIRT2497949	hsa-miR-3929	CLIP-seq
MIRT2497950	hsa-miR-3975	CLIP-seq
MIRT2497951	hsa-miR-4252	CLIP-seq
MIRT2497952	hsa-miR-4290	CLIP-seq
MIRT2497953	hsa-miR-4302	CLIP-seq
MIRT2497954	hsa-miR-4419b	CLIP-seq
MIRT2497955	hsa-miR-4425	CLIP-seq
MIRT2497956	hsa-miR-4429	CLIP-seq
MIRT2497957	hsa-miR-4450	CLIP-seq
MIRT2497958	hsa-miR-4478	CLIP-seq
MIRT2497959	hsa-miR-4483	CLIP-seq
MIRT2497960	hsa-miR-4527	CLIP-seq
MIRT868044	hsa-miR-4643	CLIP-seq
MIRT868045	hsa-miR-4652-5p	CLIP-seq
MIRT2497961	hsa-miR-4667-5p	CLIP-seq
MIRT2497962	hsa-miR-4669	CLIP-seq
MIRT2497963	hsa-miR-4689	CLIP-seq
MIRT2497964	hsa-miR-4700-5p	CLIP-seq
MIRT2497965	hsa-miR-4701-5p	CLIP-seq
MIRT868049	hsa-miR-4717-3p	CLIP-seq
MIRT2497966	hsa-miR-4720-5p	CLIP-seq
MIRT2497967	hsa-miR-4722-3p	CLIP-seq
MIRT2497968	hsa-miR-4728-5p	CLIP-seq
MIRT2497969	hsa-miR-4781-3p	CLIP-seq
MIRT2497970	hsa-miR-4784	CLIP-seq
MIRT2497971	hsa-miR-4789-3p	CLIP-seq
MIRT868051	hsa-miR-4797-5p	CLIP-seq
MIRT2497972	hsa-miR-4799-3p	CLIP-seq
MIRT868053	hsa-miR-4802-3p	CLIP-seq
MIRT2497973	hsa-miR-485-5p	CLIP-seq
MIRT2497974	hsa-miR-548s	CLIP-seq
MIRT2497975	hsa-miR-555	CLIP-seq
MIRT2497976	hsa-miR-588	CLIP-seq
MIRT2497977	hsa-miR-626	CLIP-seq
MIRT868056	hsa-miR-642b	CLIP-seq
MIRT2497978	hsa-miR-939	CLIP-seq
MIRT2497927	hsa-miR-1225-5p	CLIP-seq
MIRT2497929	hsa-miR-128	CLIP-seq
MIRT2497930	hsa-miR-1293	CLIP-seq
MIRT2497931	hsa-miR-1913	CLIP-seq
MIRT2497932	hsa-miR-1976	CLIP-seq
MIRT2497935	hsa-miR-3147	CLIP-seq
MIRT2497940	hsa-miR-320a	CLIP-seq
MIRT2497941	hsa-miR-320b	CLIP-seq
MIRT2497942	hsa-miR-320c	CLIP-seq
MIRT2497943	hsa-miR-320d	CLIP-seq
MIRT2497944	hsa-miR-324-3p	CLIP-seq
MIRT2497946	hsa-miR-3657	CLIP-seq
MIRT2497947	hsa-miR-370	CLIP-seq
MIRT2497948	hsa-miR-3926	CLIP-seq
MIRT2497951	hsa-miR-4252	CLIP-seq
MIRT2497952	hsa-miR-4290	CLIP-seq
MIRT2497953	hsa-miR-4302	CLIP-seq
MIRT2497955	hsa-miR-4425	CLIP-seq
MIRT2497956	hsa-miR-4429	CLIP-seq
MIRT2497957	hsa-miR-4450	CLIP-seq
MIRT2497959	hsa-miR-4483	CLIP-seq
MIRT2497961	hsa-miR-4667-5p	CLIP-seq
MIRT2497962	hsa-miR-4669	CLIP-seq
MIRT2497964	hsa-miR-4700-5p	CLIP-seq
MIRT2497965	hsa-miR-4701-5p	CLIP-seq
MIRT2497967	hsa-miR-4722-3p	CLIP-seq
MIRT2497969	hsa-miR-4781-3p	CLIP-seq
MIRT2497971	hsa-miR-4789-3p	CLIP-seq
MIRT868051	hsa-miR-4797-5p	CLIP-seq
MIRT2497974	hsa-miR-548s	CLIP-seq
MIRT2497975	hsa-miR-555	CLIP-seq
MIRT2497976	hsa-miR-588	CLIP-seq
MIRT2497977	hsa-miR-626	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001675	Process	Acrosome assembly	IBA
GO:0001675	Process	Acrosome assembly	ISS
GO:0002080	Component	Acrosomal membrane	IBA
GO:0002080	Component	Acrosomal membrane	IEA
GO:0002080	Component	Acrosomal membrane	ISS
GO:0005515	Function	Protein binding	IPI	25416956, 28514442
GO:0007283	Process	Spermatogenesis	IEA
GO:0007283	Process	Spermatogenesis	ISS
GO:0007338	Process	Single fertilization	IBA
GO:0007338	Process	Single fertilization	IEA
GO:0007338	Process	Single fertilization	ISS
GO:0016020	Component	Membrane	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA

Other IDs

• MIM: 611902
• HGNC: 22225
• e!Ensembl: ENSG00000128596

Protein

• UniProt ID: Q96JN2
• Protein name: Coiled-coil domain-containing protein 136 (Nasopharyngeal carcinoma-associated gene 6 protein)
• Protein function: May play a role in acrosome formation in spermatogenesis and in fertilization.
• Tissue specificity: TISSUE SPECIFICITY: Expressed in gastric tissues. Down-regulated in gastric cancer. {ECO:0000269|PubMed:15112360}.
• Sequence:

  MQAMEGEVLLPALYEEEEEEEEEEEEVEEEEEQVQKGGSVGSLSVNKHRGLSLTETELEE
  LRAQVLQLVAELEETRELAGQHEDDSLELQGLLEDERLASAQQAEVFTKQIQQLQGELRS
  LREEISLLEHEKESELKEIEQELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQN
  ELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGLSDYSGLQEELQELRERYHFLNEEY
  RALQESNSSLTGQLADLESERTQRATERWLQSQTLSMTSAESQTSEMDFLEPDPEMQLLR
  QQLRDAEEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRLQRELKCAQNEVLRFQTSHS
  VTQNEELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTELRQLKVMKSTLVENQSEKELLC
  RLQKLHLQHQNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQ
  LQEMKQLYQASKDELERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLL
  SRLTELQEKYKASQKEMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTLPLPKSGLLLK
  SQELLTKLEDLCELQLLYQGMQEEQKKLIQNQDCVLKEQLEIHEELRRFKESHFQEVLEN
  PDDSKLAKSSKCNRNKQSKLLMEQMQALQVMYDAGQAKQELLQQEQGRLLEERKRLQADL
  QLCLEEMQLLQVQSPSIKMSLESYGKSYGSMVPSNENCRKTYDTTVDDNESYYKSYTSTQ
  TSSKSFLKSYDSSTSASEAYGKSYCTTSNSSITYKKSYGSTSSSDTCQKSFVSSCTDEEP
  AEPEDMERFEEMVVKVLIKLQAVQAMYQISQEEHSQLQEQMEKLLAKQKDLKEELDACER
  EFKECMECLEKPMAPQNDKNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCC
  QEELRQLREKRPSVVKEARGKNANKNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVV
  LYYKASQRKLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQEE
  NEEDKEEEEKEEDSEEEEDDADSSLESPEENNPLRLSESKKSSPTPNPPIFSLPLVGLVV
  ISALLWCWWAETSS

• Sequence length: 1154