Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	64747
Gene name Gene Name - the full gene name approved by the HGNC.	Major facilitator superfamily domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MFSD1
Synonyms (NCBI Gene) Gene synonyms aliases	Minerva, SLC72A1, SMAP4
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q25.32

Show/Hide all(96)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023178	hsa-miR-124-3p	Microarray	18668037
MIRT049667	hsa-miR-92a-3p	CLASH	23622248
MIRT1146434	hsa-miR-3074-5p	CLIP-seq
MIRT1146435	hsa-miR-370	CLIP-seq
MIRT1146436	hsa-miR-4662a-3p	CLIP-seq
MIRT2041721	hsa-miR-425	CLIP-seq
MIRT2041722	hsa-miR-4289	CLIP-seq
MIRT2041723	hsa-miR-653	CLIP-seq
MIRT2271227	hsa-miR-3152-3p	CLIP-seq
MIRT2570388	hsa-miR-1182	CLIP-seq
MIRT2570389	hsa-miR-129-3p	CLIP-seq
MIRT2570390	hsa-miR-151-3p	CLIP-seq
MIRT2570391	hsa-miR-186	CLIP-seq
MIRT2570392	hsa-miR-188-5p	CLIP-seq
MIRT2570393	hsa-miR-2113	CLIP-seq
MIRT1146434	hsa-miR-3074-5p	CLIP-seq
MIRT2570394	hsa-miR-3133	CLIP-seq
MIRT2570395	hsa-miR-3144-3p	CLIP-seq
MIRT2570396	hsa-miR-3163	CLIP-seq
MIRT1146435	hsa-miR-370	CLIP-seq
MIRT2570397	hsa-miR-3713	CLIP-seq
MIRT2570398	hsa-miR-371b-5p	CLIP-seq
MIRT2570399	hsa-miR-3912	CLIP-seq
MIRT2570400	hsa-miR-421	CLIP-seq
MIRT2570401	hsa-miR-423-3p	CLIP-seq
MIRT2570402	hsa-miR-4282	CLIP-seq
MIRT2570403	hsa-miR-4317	CLIP-seq
MIRT2570404	hsa-miR-4446-5p	CLIP-seq
MIRT1146436	hsa-miR-4662a-3p	CLIP-seq
MIRT2570405	hsa-miR-4699-5p	CLIP-seq
MIRT2570406	hsa-miR-4709-5p	CLIP-seq
MIRT2570407	hsa-miR-4755-5p	CLIP-seq
MIRT2570408	hsa-miR-4797-3p	CLIP-seq
MIRT2570409	hsa-miR-4797-5p	CLIP-seq
MIRT2570410	hsa-miR-548a-3p	CLIP-seq
MIRT2570411	hsa-miR-548ae	CLIP-seq
MIRT2570412	hsa-miR-548aj	CLIP-seq
MIRT2570413	hsa-miR-548am	CLIP-seq
MIRT2570414	hsa-miR-548e	CLIP-seq
MIRT2570415	hsa-miR-548f	CLIP-seq
MIRT2570416	hsa-miR-548g	CLIP-seq
MIRT2570417	hsa-miR-548x	CLIP-seq
MIRT2570418	hsa-miR-561	CLIP-seq
MIRT2570419	hsa-miR-577	CLIP-seq
MIRT2570420	hsa-miR-599	CLIP-seq
MIRT2570421	hsa-miR-606	CLIP-seq
MIRT2570422	hsa-miR-616	CLIP-seq
MIRT2570423	hsa-miR-642a	CLIP-seq
MIRT2570424	hsa-miR-802	CLIP-seq
MIRT2570425	hsa-miR-875-5p	CLIP-seq
MIRT2570388	hsa-miR-1182	CLIP-seq
MIRT2570389	hsa-miR-129-3p	CLIP-seq
MIRT2570390	hsa-miR-151-3p	CLIP-seq
MIRT2570391	hsa-miR-186	CLIP-seq
MIRT2570392	hsa-miR-188-5p	CLIP-seq
MIRT2570393	hsa-miR-2113	CLIP-seq
MIRT1146434	hsa-miR-3074-5p	CLIP-seq
MIRT2570394	hsa-miR-3133	CLIP-seq
MIRT2570395	hsa-miR-3144-3p	CLIP-seq
MIRT2570396	hsa-miR-3163	CLIP-seq
MIRT1146435	hsa-miR-370	CLIP-seq
MIRT2570397	hsa-miR-3713	CLIP-seq
MIRT2570398	hsa-miR-371b-5p	CLIP-seq
MIRT2570399	hsa-miR-3912	CLIP-seq
MIRT2570400	hsa-miR-421	CLIP-seq
MIRT2570401	hsa-miR-423-3p	CLIP-seq
MIRT2570402	hsa-miR-4282	CLIP-seq
MIRT2570403	hsa-miR-4317	CLIP-seq
MIRT2570404	hsa-miR-4446-5p	CLIP-seq
MIRT1146436	hsa-miR-4662a-3p	CLIP-seq
MIRT2570405	hsa-miR-4699-5p	CLIP-seq
MIRT2570406	hsa-miR-4709-5p	CLIP-seq
MIRT2684943	hsa-miR-4732-5p	CLIP-seq
MIRT2570407	hsa-miR-4755-5p	CLIP-seq
MIRT2570408	hsa-miR-4797-3p	CLIP-seq
MIRT2570409	hsa-miR-4797-5p	CLIP-seq
MIRT2570410	hsa-miR-548a-3p	CLIP-seq
MIRT2684944	hsa-miR-548ac	CLIP-seq
MIRT2570411	hsa-miR-548ae	CLIP-seq
MIRT2570412	hsa-miR-548aj	CLIP-seq
MIRT2570413	hsa-miR-548am	CLIP-seq
MIRT2684945	hsa-miR-548d-3p	CLIP-seq
MIRT2570414	hsa-miR-548e	CLIP-seq
MIRT2570415	hsa-miR-548f	CLIP-seq
MIRT2570416	hsa-miR-548g	CLIP-seq
MIRT2570417	hsa-miR-548x	CLIP-seq
MIRT2684946	hsa-miR-548z	CLIP-seq
MIRT2570418	hsa-miR-561	CLIP-seq
MIRT2570419	hsa-miR-577	CLIP-seq
MIRT2684947	hsa-miR-587	CLIP-seq
MIRT2570420	hsa-miR-599	CLIP-seq
MIRT2570421	hsa-miR-606	CLIP-seq
MIRT2570422	hsa-miR-616	CLIP-seq
MIRT2570423	hsa-miR-642a	CLIP-seq
MIRT2570424	hsa-miR-802	CLIP-seq
MIRT2570425	hsa-miR-875-5p	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence
GO:0005764	Component	Lysosome	ISS
GO:0016021	Component	Integral component of membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0042803	Function	Protein homodimerization activity	ISS
GO:0050821	Process	Protein stabilization	ISS
GO:0055085	Process	Transmembrane transport	IEA
GO:0061462	Process	Protein localization to lysosome	ISS

MIM	HGNC	e!Ensembl
619976	25874	ENSG00000118855

Protein

UniProt ID

Q9H3U5

Protein name

Lysosomal dipeptide transporter MFSD1 (Major facilitator superfamily domain-containing protein 1) (Smooth muscle cell-associated protein 4) (SMAP-4)

Protein function

Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol (PubMed:38507452). Could play a role in a specific type of protein O-g

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07690	MFS_1	45 → 380	Major Facilitator Superfamily	Family
PF07690	MFS_1	269 → 462	Major Facilitator Superfamily	Family

Sequence

MEEEDEEARALLAGGPDEADRGAPAAPGALPALCDPSRLAHRLLVLLLMCFLGFGSYFCY
DNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFV
CIGQVVFALGGIFNAFWLMEFGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSM
ARIGSTVNMNLMGWLYSKIEALLGSAGHTTLGITLMIGGITCILSLICALALAYLDQRAE
RILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQ
AASAINSVVYVISAPMSPVFGLLVDKTGKNIIWVLCAVAATLVSHMMLAFTMWNPWIAMC
LLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAIISIIAGMILDSRGYLFL
EVFFIACVSLSLLSVVLLYLVNRAQGGNLNYSARQREEIKFSHTE

Sequence length

465

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Periodontitis	Periodontitis	rs28937571, rs104894211, rs587777534	24024966

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Tetralogy of Fallot	Tetralogy of Fallot	GWAS
Insomnia	Insomnia	GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Diabetes Mellitus	Associate	30200077
Obesity	Associate	30547318
Periodontitis	Associate	30547318

MFSD1 (major facilitator superfamily domain containing 1)