Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	64478
Gene name Gene Name - the full gene name approved by the HGNC.	CUB and Sushi multiple domains 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CSMD1
Synonyms (NCBI Gene) Gene synonyms aliases	PPP1R24
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8p23.2

Show/Hide all(146)

miRTarBase ID	miRNA	Experiments	Reference
MIRT503857	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541802	hsa-miR-338-5p	HITS-CLIP	21572407
MIRT503854	hsa-miR-4704-5p	HITS-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT503852	hsa-miR-567	HITS-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503849	hsa-miR-3924	HITS-CLIP	21572407
MIRT707186	hsa-let-7c-3p	HITS-CLIP	21572407
MIRT503848	hsa-miR-297	HITS-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT541802	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT503854	hsa-miR-4704-5p	PAR-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT503852	hsa-miR-567	PAR-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503849	hsa-miR-3924	PAR-CLIP	21572407
MIRT503848	hsa-miR-297	PAR-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT503852	hsa-miR-567	PAR-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503849	hsa-miR-3924	PAR-CLIP	21572407
MIRT503848	hsa-miR-297	PAR-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT503856	hsa-miR-4517	PAR-CLIP	23446348
MIRT503855	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT503854	hsa-miR-4704-5p	PAR-CLIP	23446348
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503852	hsa-miR-567	PAR-CLIP	23446348
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503849	hsa-miR-3924	PAR-CLIP	23446348
MIRT503848	hsa-miR-297	PAR-CLIP	23446348
MIRT503857	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541802	hsa-miR-338-5p	HITS-CLIP	21572407
MIRT503854	hsa-miR-4704-5p	HITS-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT503852	hsa-miR-567	HITS-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503849	hsa-miR-3924	HITS-CLIP	21572407
MIRT707186	hsa-let-7c-3p	HITS-CLIP	21572407
MIRT503848	hsa-miR-297	HITS-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT541802	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT503854	hsa-miR-4704-5p	PAR-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT503852	hsa-miR-567	PAR-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503849	hsa-miR-3924	PAR-CLIP	21572407
MIRT503848	hsa-miR-297	PAR-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT503852	hsa-miR-567	PAR-CLIP	21572407
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503849	hsa-miR-3924	PAR-CLIP	21572407
MIRT503848	hsa-miR-297	PAR-CLIP	21572407
MIRT503857	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT503856	hsa-miR-4517	PAR-CLIP	23446348
MIRT503855	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT503854	hsa-miR-4704-5p	PAR-CLIP	23446348
MIRT503853	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503852	hsa-miR-567	PAR-CLIP	23446348
MIRT503851	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT503850	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503849	hsa-miR-3924	PAR-CLIP	23446348
MIRT503848	hsa-miR-297	PAR-CLIP	23446348
MIRT911939	hsa-miR-103b	CLIP-seq
MIRT911940	hsa-miR-10a	CLIP-seq
MIRT911941	hsa-miR-10b	CLIP-seq
MIRT911942	hsa-miR-130a	CLIP-seq
MIRT911943	hsa-miR-130b	CLIP-seq
MIRT911944	hsa-miR-15a	CLIP-seq
MIRT911945	hsa-miR-15b	CLIP-seq
MIRT911946	hsa-miR-16	CLIP-seq
MIRT911947	hsa-miR-195	CLIP-seq
MIRT911948	hsa-miR-19a	CLIP-seq
MIRT911949	hsa-miR-19b	CLIP-seq
MIRT911950	hsa-miR-2467-3p	CLIP-seq
MIRT911951	hsa-miR-301a	CLIP-seq
MIRT911952	hsa-miR-301b	CLIP-seq
MIRT911953	hsa-miR-3123	CLIP-seq
MIRT911954	hsa-miR-3149	CLIP-seq
MIRT911955	hsa-miR-3167	CLIP-seq
MIRT911956	hsa-miR-3182	CLIP-seq
MIRT911957	hsa-miR-3613-3p	CLIP-seq
MIRT911958	hsa-miR-3666	CLIP-seq
MIRT911959	hsa-miR-3674	CLIP-seq
MIRT911960	hsa-miR-3678-3p	CLIP-seq
MIRT911961	hsa-miR-376a	CLIP-seq
MIRT911962	hsa-miR-376b	CLIP-seq
MIRT911963	hsa-miR-3919	CLIP-seq
MIRT911964	hsa-miR-424	CLIP-seq
MIRT911965	hsa-miR-4291	CLIP-seq
MIRT911966	hsa-miR-4295	CLIP-seq
MIRT911967	hsa-miR-4310	CLIP-seq
MIRT911968	hsa-miR-4328	CLIP-seq
MIRT911969	hsa-miR-4421	CLIP-seq
MIRT911970	hsa-miR-4533	CLIP-seq
MIRT911971	hsa-miR-4535	CLIP-seq
MIRT911972	hsa-miR-454	CLIP-seq
MIRT911973	hsa-miR-4652-3p	CLIP-seq
MIRT911974	hsa-miR-4671-3p	CLIP-seq
MIRT911975	hsa-miR-4776-5p	CLIP-seq
MIRT911976	hsa-miR-4797-5p	CLIP-seq
MIRT911977	hsa-miR-492	CLIP-seq
MIRT911978	hsa-miR-497	CLIP-seq
MIRT911979	hsa-miR-568	CLIP-seq
MIRT911980	hsa-miR-603	CLIP-seq
MIRT911981	hsa-miR-616	CLIP-seq
MIRT911982	hsa-miR-643	CLIP-seq
MIRT911983	hsa-miR-759	CLIP-seq
MIRT911984	hsa-miR-876-5p	CLIP-seq
MIRT1920378	hsa-miR-369-3p	CLIP-seq
MIRT1920379	hsa-miR-374a	CLIP-seq
MIRT1920380	hsa-miR-374b	CLIP-seq
MIRT1970313	hsa-miR-1200	CLIP-seq
MIRT1970314	hsa-miR-3074-5p	CLIP-seq
MIRT1970315	hsa-miR-3140-3p	CLIP-seq
MIRT911967	hsa-miR-4310	CLIP-seq
MIRT1970316	hsa-miR-4714-5p	CLIP-seq
MIRT911983	hsa-miR-759	CLIP-seq
MIRT2206260	hsa-miR-141	CLIP-seq
MIRT2206261	hsa-miR-200a	CLIP-seq
MIRT2206262	hsa-miR-3153	CLIP-seq
MIRT2206263	hsa-miR-361-5p	CLIP-seq
MIRT2206264	hsa-miR-3647-3p	CLIP-seq
MIRT2206265	hsa-miR-365	CLIP-seq
MIRT911970	hsa-miR-4533	CLIP-seq
MIRT2206266	hsa-miR-4668-5p	CLIP-seq
MIRT911983	hsa-miR-759	CLIP-seq
MIRT1920378	hsa-miR-369-3p	CLIP-seq
MIRT1920379	hsa-miR-374a	CLIP-seq
MIRT1920380	hsa-miR-374b	CLIP-seq
MIRT1920378	hsa-miR-369-3p	CLIP-seq
MIRT1920379	hsa-miR-374a	CLIP-seq
MIRT1920380	hsa-miR-374b	CLIP-seq
MIRT2509568	hsa-miR-3671	CLIP-seq
MIRT1920378	hsa-miR-369-3p	CLIP-seq
MIRT1920379	hsa-miR-374a	CLIP-seq
MIRT1920380	hsa-miR-374b	CLIP-seq

Show/Hide all(1)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016021	Component	Integral component of membrane	IEA

MIM	HGNC	e!Ensembl
608397	14026	ENSG00000183117

Protein

UniProt ID

Q96PZ7

Protein name

CUB and sushi domain-containing protein 1 (CUB and sushi multiple domains protein 1)

Protein function

Potential suppressor of squamous cell carcinomas.

PDB

2EHF

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00431	CUB	32 → 137	CUB domain	Domain
PF00084	Sushi	145 → 202	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	208 → 309	CUB domain	Domain
PF00084	Sushi	349 → 406	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	411 → 519	CUB domain	Domain
PF00084	Sushi	527 → 580	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	584 → 689	CUB domain	Domain
PF00084	Sushi	697 → 754	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	758 → 863	CUB domain	Domain
PF00084	Sushi	873 → 926	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	930 → 1037	CUB domain	Domain
PF00084	Sushi	1045 → 1100	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1104 → 1209	CUB domain	Domain
PF00084	Sushi	1217 → 1273	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1277 → 1383	CUB domain	Domain
PF00084	Sushi	1391 → 1447	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1451 → 1556	CUB domain	Domain
PF00084	Sushi	1564 → 1621	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1625 → 1730	CUB domain	Domain
PF00084	Sushi	1741 → 1798	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1802 → 1907	CUB domain	Domain
PF00084	Sushi	1915 → 1970	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	1974 → 2079	CUB domain	Domain
PF00084	Sushi	2087 → 2142	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	2146 → 2249	CUB domain	Domain
PF00084	Sushi	2258 → 2315	Sushi repeat (SCR repeat)	Domain
PF00431	CUB	2319 → 2427	CUB domain	Domain
PF00084	Sushi	2432 → 2490	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2495 → 2552	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2571 → 2617	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2622 → 2675	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2680 → 2733	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2738 → 2791	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2796 → 2854	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2859 → 2912	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2920 → 2973	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	2978 → 3032	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	3037 → 3092	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	3097 → 3150	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	3155 → 3208	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	3216 → 3270	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	3275 → 3330	Sushi repeat (SCR repeat)	Domain

Tissue specificity

TISSUE SPECIFICITY: Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, hippocampus and fetal brain. {ECO:0000269|PubMed:11572484}.

Sequence

MTAWRRFQSLLLLLGLLVLCARLLTAAKGQNCGGLVQGPNGTIESPGFPHGYPNYANCTW
IIITGERNRIQLSFHTFALEEDFDILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTL
WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH
AILTCIVSPGNGASWDFPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILA
EPGDTIALVFTDFQLEEGYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNH
RRKGFNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRR
AGSDFRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSG
VITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSV
LYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTG
SSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNY
PEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVP
SQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVS
FHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKD
SLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLIST
GNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCD
PGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTI
EVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQL
RFISDFSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGA
TKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGK
GIHLRTRSFQLFEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD
TDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLS
GDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHF
IVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFS
IQFSTSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFW
QPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP
SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKP
REACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPS
CNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL
FDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQ
CSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVV
PCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHD
GGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPAL
PSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLST
LGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPM
IGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMIN
SDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQNGTIYSP
GFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQLGVFSGNT
ALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGD
FVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGN
YFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSN
FTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCK
PGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYE
CHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEY
GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY
GATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRD
TVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVV
NFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYG
MSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAV
VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKS
LLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSS
VIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVS
YQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSIS
YSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQ
CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVF
FRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVY
TCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKG
YYEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKKEEAHLLLKAFQIKGQ
ADIFVSKFENDNWGLDGYVSSGLERGGFTFQGDIHGKDFGKFKLERQDPLNPDQDSSSHY
HGTSSGSVAAAILVPFFALILSGFAFYLYKHRTRPKVQYNGYAGHENSNGQASFENPMYD
TNLKPTEAKAVRFDTTLNTVCTVV

Sequence length

3564

Interactions

View interactions

Show/Hide Causal Diseases (7)

Disease term	Disease name	dbSNP ID	References
Causal
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039 View all (65 more)	23535033, 30514930
Arthritis	Juvenile arthritis	rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470	24709693
Attention deficit hyperactivity disorder	Attention deficit hyperactivity disorder	rs786205019	23453885
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	24185611
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	20953187, 25574825
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	23839771, 21926974, 24166486, 24630139, 23319000, 24244513, 23453885, 22688191, 28991256, 24387768, 31268507, 25056061, 29483656, 30285260, 26198764

Show/Hide Unknown Diseases (19)

Disease term	Disease name	Evidence	References	Source
Unknown
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease		25241909	ClinVar
Mental depression	Major Depressive Disorder		23453885	ClinVar
Autism Spectrum Disorder	autism spectrum disorder			GenCC
Neurodevelopmental Disorders	complex neurodevelopmental disorder			GenCC
Neuroticism	Neuroticism			GWAS
Gastroesophageal Reflux Disease	Gastroesophageal Reflux Disease			GWAS
Multiple Sclerosis	Multiple Sclerosis			GWAS
Stress Disorder	Stress Disorder			GWAS
Uterine Fibroids	Uterine Fibroids			GWAS
Metabolic Syndrome	Metabolic Syndrome			GWAS
Mental Depression	Mental Depression			GWAS
Neuroblastoma	Neuroblastoma	Loss of SNAI2 function reduces self-renewal, 3D invasion as well as metastatic spread in vivo, while strongly sensitizing neuroblastoma cells to RA-induced growth inhibition.		GWAS, CBGDA
Diabetes	Diabetes			GWAS
Strabismus	Strabismus			GWAS
Dementia	Dementia			GWAS
Crohn Disease	Crohn Disease			GWAS
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.		GWAS, CBGDA
Insomnia	Insomnia			GWAS
Glioblastoma	Glioblastoma	CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587		GWAS, CBGDA

Show/Hide Text Mining Associations (53)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	33506581
Alzheimer Disease	Associate	25024348, 35627222, 36553611
Anxiety Disorders	Associate	40362533
Asthma	Associate	24876173
Autism Spectrum Disorder	Associate	28281572, 38421723
Bipolar Disorder	Associate	24387768, 28525603
Brain Diseases	Associate	40362533
Breast Neoplasms	Inhibit	19276661, 28534981, 34404439
Breast Neoplasms	Associate	32701512
Carcinoma Basal Cell	Inhibit	19276661
Carcinoma Hepatocellular	Associate	26076954, 32685003, 33558447
Carcinoma Neuroendocrine	Associate	34326338
Carcinoma Squamous Cell	Inhibit	19276661
Colorectal Neoplasms	Associate	19359472, 23505554, 24408017, 24694993
Compulsive Personality Disorder	Associate	40362533
Congenital Hyperinsulinism	Associate	23869231
Depressive Disorder	Associate	39457114
Developmental Disabilities	Associate	38421723, 40362533
Epilepsy	Associate	32315120
Essential Hypertension	Associate	25695618
Facial Dysmorphism with Multiple Malformations	Associate	40362533
Fibrous Dysplasia Polyostotic	Associate	26651848
Hypertension	Associate	25695618, 39683541
Inflammation	Associate	19132087
Insulin Resistance	Associate	31127295
Intellectual Disability	Associate	36854624, 40362533
Leukemia Myeloid Acute	Associate	32011516
Leukemia Myelomonocytic Chronic	Associate	26648538
Lung Diseases	Inhibit	19276661
Lymphoma Non Hodgkin	Associate	19383911
Mental Disorders	Associate	39457114
Metabolic Diseases	Associate	32902719
Migraine Disorders	Associate	32315120
Mucocutaneous Lymph Node Syndrome	Associate	19132087
Multiple Pulmonary Nodules	Associate	26076954
Neonatal Systemic lupus erythematosus	Associate	22886516
Neoplasm Recurrence Local	Associate	34326338
Neoplasms	Inhibit	18460741, 19276661, 19359472, 22558405, 23505554, 24408017, 26483173, 28534981
Neoplasms	Associate	24477574, 30545040, 33810183, 34326338, 34404439, 39238637
Neuroblastoma	Associate	22367537
Osteoporosis	Associate	29725052
Parkinson Disease	Associate	33818904
Pdgfrb Associated Chronic Eosinophilic Leukemia	Associate	32011516
Peripheral Arterial Disease	Associate	20610895
Pulmonary Disease Chronic Obstructive	Associate	24876173
Schizophrenia	Associate	22883350, 24387768, 27890662, 28525603, 37511534, 40362533
Sleep Initiation and Maintenance Disorders	Associate	33530007
Squamous Cell Carcinoma of Head and Neck	Inhibit	19276661
Squamous Cell Carcinoma of Head and Neck	Associate	24278325, 30545040, 31427592
Stomach Neoplasms	Associate	32034058
Stress Disorders Post Traumatic	Associate	35836289
Triple Negative Breast Neoplasms	Associate	34404439
Uveal melanoma	Associate	27745836

CSMD1 (CUB and Sushi multiple domains 1)