SUDS3 (SIN3A corepressor complex component SDS3)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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64426 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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SIN3A corepressor complex component SDS3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SUDS3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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SAP45, SDS3 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q24.23 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9H7L9 | ||||||||||
| Protein name | Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) | ||||||||||
| Protein function | Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity o | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in various cancer cell ines. {ECO:0000269|PubMed:12724404}. | ||||||||||
| Sequence |
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| Sequence length | 328 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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