SUDS3 (SIN3A corepressor complex component SDS3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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64426 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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SIN3A corepressor complex component SDS3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SUDS3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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SAP45, SDS3 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q24.23 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9H7L9 | ||||||||||
Protein name | Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) | ||||||||||
Protein function | Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity o | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in various cancer cell ines. {ECO:0000269|PubMed:12724404}. | ||||||||||
Sequence |
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Sequence length | 328 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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