Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
643853
Gene name Gene Name - the full gene name approved by the HGNC.
Transmembrane protein with metallophosphoesterase domain
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TMPPE
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p22.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT612364 hsa-miR-548g-3p HITS-CLIP 23313552
MIRT676550 hsa-miR-329-3p HITS-CLIP 23313552
MIRT676549 hsa-miR-362-3p HITS-CLIP 23313552
MIRT608260 hsa-miR-603 HITS-CLIP 23313552
MIRT676547 hsa-miR-3941 HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0016021 Component Integral component of membrane IEA
GO:0016787 Function Hydrolase activity IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q6ZT21
Protein name Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00149 Metallophos 207 395 Calcineurin-like phosphoesterase Domain
Sequence
MAIFRQLSLGAKATLAAVTVFVSMIASRSYLAESLELRAWRWLLRLQLALFVNSLLLIGS
LYIWRSTVSNLCHSPAAESTCFQLWKVVVLAFLALAHSSFFTMFFLVAEEPYLFSLAAYS
CLGAYIIMLFFLFILSGMEQAYQLLAWRSGRVVGSLEKTRKLVLRPALAVGVTAVLSVAG
ILNAAQPPAVKTVEVPIHQLPASMNNLKIVLLSDIHLGPTVGRTKMEMFVRMVNVLEPDI
TVIVGDLSDSEASVLRTAVAPLGQLHSHLGAYFVTGNHEYYTSDVSNWFALLESLHVQPL
HNENVKISATRAQRGGGGSGSGSEDEDWICLAGVDDIEADILHYSGHGMDLDKALEGCSP
DHTIILLAHQPLAAKRALQARPDINLILSGHTHAG
QIFPLNVAAYLLNPFFAGLYQVAQA
TFVYVSPGTAYYGIPMRLGSRAEITELILQRSP
Sequence length 453
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Gangliosidosis Gangliosidosis GM1, Gangliosidosis, Generalized GM1, Type 1 (disorder), Gangliosidosis, Generalized GM1, Type 2, Gangliosidosis, Generalized GM1, Type 3 rs72555359, rs72555360, rs72555390, rs28934274, rs72555361, rs72555362, rs72555391, rs587776524, rs72555393, rs587776525, rs72555366, rs72555370, rs72555392, rs587776526, rs397515616
View all (27 more)
8199591, 8198123, 29160035
Mucopolysaccharidosis Mucopolysaccharidosis type IVB rs118204435, rs118204437, rs118204438, rs118204439, rs118204441, rs118204442, rs118204448, rs118204443, rs118204444, rs118204449, rs118204446, rs118204447, rs118203939, rs118203941, rs431905493
View all (577 more)
8199591, 8198123, 21497194, 29160035