MS4A6A (membrane spanning 4-domains A6A)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64231
Gene name Gene Name - the full gene name approved by the HGNC.
Membrane spanning 4-domains A6A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MS4A6A
Synonyms (NCBI Gene) Gene synonyms aliases
4SPAN3, 4SPAN3.2, CD20L3, CDA01, MS4A6, MST090, MSTP090
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(15)
miRTarBase ID miRNA Experiments Reference
MIRT2046228 hsa-miR-3192 CLIP-seq
MIRT2046229 hsa-miR-4314 CLIP-seq
MIRT2046230 hsa-miR-4424 CLIP-seq
MIRT2046231 hsa-miR-4646-5p CLIP-seq
MIRT2046232 hsa-miR-491-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005802 Component Trans-Golgi network IBA
GO:0005802 Component Trans-Golgi network IDA 23874341
GO:0005886 Component Plasma membrane IBA
GO:0007166 Process Cell surface receptor signaling pathway IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
606548 13375 ENSG00000110077
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9H2W1
Protein name Membrane-spanning 4-domains subfamily A member 6A (CD20 antigen-like 3) (Four-span transmembrane protein 3)
Protein function May be involved in signal transduction as a component of a multimeric receptor complex.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04103 CD20 47 → 208 CD20-like family Family
Tissue specificity TISSUE SPECIFICITY: Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines.
Sequence
Sequence length 248
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (2)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Alzheimer disease Alzheimer's disease or family history of Alzheimer's disease N/A N/A GWAS
Dementia Dementia N/A N/A GWAS
Show/Hide Text Mining Associations (20)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 37578930
Alzheimer Disease Associate 22445811, 23226438, 23360175, 23954108, 25189118, 25778476, 26365416, 27244883, 28650998, 29179108, 30448613, 31144443, 32588970, 33712570, 34092785
View all (6 more)
Atrophy Associate 27244883
Carcinoma Non Small Cell Lung Inhibit 36969247
Cognitive Dysfunction Associate 25189118
Disease Associate 24438528
Down Syndrome Associate 24438528
Gastritis Associate 36973348
Glioblastoma Associate 26506879
Glioma Associate 36119086