Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	64225
Gene name	Atlastin GTPase 2
Gene symbol	ATL2
Synonyms (NCBI Gene)	ARL3IP2ARL6IP2ATL-2aip-2atlastin2
Chromosome	2
Chromosome location	2p22.2-p22.1

338

Show/Hide all (338)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020733	hsa-miR-155-5p	Proteomics	18668040
MIRT021152	hsa-miR-186-5p	Sequencing	20371350
MIRT021317	hsa-miR-125a-5p	Sequencing	20371350
MIRT024158	hsa-miR-221-3p	Sequencing	20371350
MIRT028540	hsa-miR-30a-5p	Proteomics	18668040
MIRT031714	hsa-miR-16-5p	Proteomics	18668040
MIRT042321	hsa-miR-484	CLASH	23622248
MIRT705452	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT705451	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT705450	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT705449	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT705448	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT705447	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT705446	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT705445	hsa-miR-661	HITS-CLIP	23313552
MIRT705444	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT705443	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT705442	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT705441	hsa-miR-7703	HITS-CLIP	23313552
MIRT705440	hsa-miR-1262	HITS-CLIP	23313552
MIRT705439	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT705438	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT441162	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441162	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT705440	hsa-miR-1262	PAR-CLIP	27292025
MIRT705451	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT705439	hsa-miR-4701-3p	PAR-CLIP	27292025
MIRT705447	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT705452	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT705444	hsa-miR-542-3p	PAR-CLIP	27292025
MIRT705443	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT705445	hsa-miR-661	PAR-CLIP	27292025
MIRT705442	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT705438	hsa-miR-6736-5p	PAR-CLIP	27292025
MIRT705449	hsa-miR-6742-3p	PAR-CLIP	27292025
MIRT705446	hsa-miR-6776-5p	PAR-CLIP	27292025
MIRT705450	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT705448	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT705441	hsa-miR-7703	PAR-CLIP	27292025
MIRT705452	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT705451	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT705450	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT705449	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT705448	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT705447	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT705446	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT705445	hsa-miR-661	HITS-CLIP	23313552
MIRT705444	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT705443	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT705442	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT705441	hsa-miR-7703	HITS-CLIP	23313552
MIRT705440	hsa-miR-1262	HITS-CLIP	23313552
MIRT705439	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT705438	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805793	hsa-miR-139-5p	CLIP-seq
MIRT805794	hsa-miR-183	CLIP-seq
MIRT805795	hsa-miR-186	CLIP-seq
MIRT805796	hsa-miR-18a	CLIP-seq
MIRT805797	hsa-miR-18b	CLIP-seq
MIRT805798	hsa-miR-1908	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805801	hsa-miR-204	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT805803	hsa-miR-211	CLIP-seq
MIRT805804	hsa-miR-219-5p	CLIP-seq
MIRT805805	hsa-miR-224	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT805807	hsa-miR-28-5p	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT805809	hsa-miR-299-5p	CLIP-seq
MIRT805810	hsa-miR-30a	CLIP-seq
MIRT805811	hsa-miR-30b	CLIP-seq
MIRT805812	hsa-miR-30c	CLIP-seq
MIRT805813	hsa-miR-30d	CLIP-seq
MIRT805814	hsa-miR-30e	CLIP-seq
MIRT805815	hsa-miR-31	CLIP-seq
MIRT805816	hsa-miR-3139	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805821	hsa-miR-3611	CLIP-seq
MIRT805822	hsa-miR-3662	CLIP-seq
MIRT805823	hsa-miR-3664-5p	CLIP-seq
MIRT805824	hsa-miR-3682-5p	CLIP-seq
MIRT805825	hsa-miR-3688-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT805827	hsa-miR-377	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805829	hsa-miR-3938	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT805831	hsa-miR-412	CLIP-seq
MIRT805832	hsa-miR-4266	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805834	hsa-miR-4328	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT805836	hsa-miR-4424	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805838	hsa-miR-4445	CLIP-seq
MIRT805839	hsa-miR-4452	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT805842	hsa-miR-4652-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805845	hsa-miR-4670-3p	CLIP-seq
MIRT805846	hsa-miR-4676-5p	CLIP-seq
MIRT805847	hsa-miR-4677-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT805849	hsa-miR-4696	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT805852	hsa-miR-4704-5p	CLIP-seq
MIRT805853	hsa-miR-4720-3p	CLIP-seq
MIRT805854	hsa-miR-4735-3p	CLIP-seq
MIRT805855	hsa-miR-4755-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT805858	hsa-miR-4780	CLIP-seq
MIRT805859	hsa-miR-4782-3p	CLIP-seq
MIRT805860	hsa-miR-4786-3p	CLIP-seq
MIRT805861	hsa-miR-4804-3p	CLIP-seq
MIRT805862	hsa-miR-508-3p	CLIP-seq
MIRT805863	hsa-miR-5095	CLIP-seq
MIRT805864	hsa-miR-513a-3p	CLIP-seq
MIRT805865	hsa-miR-541	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805867	hsa-miR-548a-3p	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT805869	hsa-miR-548e	CLIP-seq
MIRT805870	hsa-miR-548f	CLIP-seq
MIRT805871	hsa-miR-548g	CLIP-seq
MIRT805872	hsa-miR-575	CLIP-seq
MIRT805873	hsa-miR-582-5p	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT805875	hsa-miR-603	CLIP-seq
MIRT805876	hsa-miR-606	CLIP-seq
MIRT805877	hsa-miR-623	CLIP-seq
MIRT805878	hsa-miR-659	CLIP-seq
MIRT805879	hsa-miR-663	CLIP-seq
MIRT805880	hsa-miR-708	CLIP-seq
MIRT805881	hsa-miR-885-3p	CLIP-seq
MIRT805882	hsa-miR-9	CLIP-seq
MIRT805883	hsa-miR-935	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT1937945	hsa-miR-2355-5p	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT1937948	hsa-miR-3143	CLIP-seq
MIRT1937949	hsa-miR-3163	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT1937951	hsa-miR-4311	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT1937955	hsa-miR-4760-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT805792	hsa-miR-1296	CLIP-seq
MIRT805793	hsa-miR-139-5p	CLIP-seq
MIRT805798	hsa-miR-1908	CLIP-seq
MIRT805804	hsa-miR-219-5p	CLIP-seq
MIRT805805	hsa-miR-224	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805808	hsa-miR-2909	CLIP-seq
MIRT805809	hsa-miR-299-5p	CLIP-seq
MIRT805810	hsa-miR-30a	CLIP-seq
MIRT805811	hsa-miR-30b	CLIP-seq
MIRT805812	hsa-miR-30c	CLIP-seq
MIRT805813	hsa-miR-30d	CLIP-seq
MIRT805814	hsa-miR-30e	CLIP-seq
MIRT2177446	hsa-miR-3157-3p	CLIP-seq
MIRT805820	hsa-miR-340	CLIP-seq
MIRT805821	hsa-miR-3611	CLIP-seq
MIRT805823	hsa-miR-3664-5p	CLIP-seq
MIRT805824	hsa-miR-3682-5p	CLIP-seq
MIRT805825	hsa-miR-3688-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT805827	hsa-miR-377	CLIP-seq
MIRT805829	hsa-miR-3938	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT805831	hsa-miR-412	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805834	hsa-miR-4328	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT805837	hsa-miR-4436b-3p	CLIP-seq
MIRT805838	hsa-miR-4445	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT805846	hsa-miR-4676-5p	CLIP-seq
MIRT805847	hsa-miR-4677-3p	CLIP-seq
MIRT805848	hsa-miR-4679	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT805852	hsa-miR-4704-5p	CLIP-seq
MIRT805856	hsa-miR-4761-3p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT805859	hsa-miR-4782-3p	CLIP-seq
MIRT805860	hsa-miR-4786-3p	CLIP-seq
MIRT2177447	hsa-miR-4796-5p	CLIP-seq
MIRT805862	hsa-miR-508-3p	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805865	hsa-miR-541	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805872	hsa-miR-575	CLIP-seq
MIRT805873	hsa-miR-582-5p	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT805875	hsa-miR-603	CLIP-seq
MIRT805876	hsa-miR-606	CLIP-seq
MIRT805878	hsa-miR-659	CLIP-seq
MIRT805879	hsa-miR-663	CLIP-seq
MIRT805881	hsa-miR-885-3p	CLIP-seq
MIRT805882	hsa-miR-9	CLIP-seq
MIRT805883	hsa-miR-935	CLIP-seq
MIRT805839	hsa-miR-4452	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT2480903	hsa-miR-1283	CLIP-seq
MIRT2480904	hsa-miR-1323	CLIP-seq
MIRT2480905	hsa-miR-140-3p	CLIP-seq
MIRT2480906	hsa-miR-142-3p	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT1937945	hsa-miR-2355-5p	CLIP-seq
MIRT2480907	hsa-miR-24	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT2480908	hsa-miR-3124-3p	CLIP-seq
MIRT1937949	hsa-miR-3163	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT2480909	hsa-miR-3677-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT2480910	hsa-miR-374c	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT2480911	hsa-miR-4282	CLIP-seq
MIRT2480912	hsa-miR-4284	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT2480913	hsa-miR-4484	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT2480914	hsa-miR-4776-3p	CLIP-seq
MIRT2480915	hsa-miR-511	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT805871	hsa-miR-548g	CLIP-seq
MIRT2480916	hsa-miR-548o	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT2480917	hsa-miR-655	CLIP-seq
MIRT1937942	hsa-miR-101	CLIP-seq
MIRT1937943	hsa-miR-103b	CLIP-seq
MIRT1937944	hsa-miR-1193	CLIP-seq
MIRT2480903	hsa-miR-1283	CLIP-seq
MIRT2480904	hsa-miR-1323	CLIP-seq
MIRT2480905	hsa-miR-140-3p	CLIP-seq
MIRT2480906	hsa-miR-142-3p	CLIP-seq
MIRT805799	hsa-miR-200b	CLIP-seq
MIRT805800	hsa-miR-200c	CLIP-seq
MIRT805802	hsa-miR-2054	CLIP-seq
MIRT2480907	hsa-miR-24	CLIP-seq
MIRT805806	hsa-miR-2682	CLIP-seq
MIRT1937946	hsa-miR-27a	CLIP-seq
MIRT1937947	hsa-miR-27b	CLIP-seq
MIRT805817	hsa-miR-3171	CLIP-seq
MIRT805818	hsa-miR-33a	CLIP-seq
MIRT805819	hsa-miR-33b	CLIP-seq
MIRT2480909	hsa-miR-3677-5p	CLIP-seq
MIRT805826	hsa-miR-3714	CLIP-seq
MIRT2480910	hsa-miR-374c	CLIP-seq
MIRT805828	hsa-miR-380	CLIP-seq
MIRT805830	hsa-miR-3942-5p	CLIP-seq
MIRT2480912	hsa-miR-4284	CLIP-seq
MIRT1937950	hsa-miR-4289	CLIP-seq
MIRT805833	hsa-miR-429	CLIP-seq
MIRT805835	hsa-miR-4422	CLIP-seq
MIRT2480913	hsa-miR-4484	CLIP-seq
MIRT805840	hsa-miR-4493	CLIP-seq
MIRT805841	hsa-miR-449c	CLIP-seq
MIRT1937952	hsa-miR-4645-3p	CLIP-seq
MIRT1937953	hsa-miR-4659a-3p	CLIP-seq
MIRT805843	hsa-miR-4659a-5p	CLIP-seq
MIRT1937954	hsa-miR-4659b-3p	CLIP-seq
MIRT805844	hsa-miR-4659b-5p	CLIP-seq
MIRT805850	hsa-miR-4700-3p	CLIP-seq
MIRT805851	hsa-miR-4703-5p	CLIP-seq
MIRT1937956	hsa-miR-4764-3p	CLIP-seq
MIRT805857	hsa-miR-4774-5p	CLIP-seq
MIRT2480914	hsa-miR-4776-3p	CLIP-seq
MIRT2480915	hsa-miR-511	CLIP-seq
MIRT1937957	hsa-miR-513a-5p	CLIP-seq
MIRT805866	hsa-miR-543	CLIP-seq
MIRT805868	hsa-miR-548an	CLIP-seq
MIRT2480916	hsa-miR-548o	CLIP-seq
MIRT805874	hsa-miR-586	CLIP-seq
MIRT2480917	hsa-miR-655	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	15161933, 19665976, 23969831, 35271311
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	18270207
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	18270207
GO:0007029	Process	Endoplasmic reticulum organization	IBA
GO:0007029	Process	Endoplasmic reticulum organization	IEA
GO:0007030	Process	Golgi organization	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016320	Process	Endoplasmic reticulum membrane fusion	IMP	22065636, 27619977
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051260	Process	Protein homooligomerization	IBA
GO:0051260	Process	Protein homooligomerization	IEA
GO:0098826	Component	Endoplasmic reticulum tubular network membrane	IDA	22065636, 27619977
GO:0098826	Component	Endoplasmic reticulum tubular network membrane	IEA
GO:0140523	Function	GTPase-dependent fusogenic activity	IDA	22065636
GO:1990809	Process	Endoplasmic reticulum tubular network membrane organization	IMP	18270207, 19665976, 22065636, 27619977

MIM	HGNC	e!Ensembl
609368	24047	ENSG00000119787

Q8NHH9

Protein name

Atlastin-2 (ATL-2) (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2)

Protein function

Atlastin-2 (ATL2) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02263	GBP	70 → 341	Guanylate-binding protein, N-terminal domain	Domain
PF02841	GBP_C	343 → 473	Guanylate-binding protein, C-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in peripheral tissues (at protein level). {ECO:0000269|PubMed:18270207}.

Sequence

MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP
VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN
KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS
QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM
FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG
LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI
KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD
LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA
VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET
LWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD

Sequence length

583

Interactions

View interactions

Show/Hide Unknown Diseases (17)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs77626845	RCV005910760
Cervical cancer	Benign	rs77626845	RCV005910764
Clear cell carcinoma of kidney	Benign	rs77626845	RCV005910765
Colon adenocarcinoma	Benign	rs77626845	RCV005910759
Colorectal cancer	Benign	rs77626845	RCV005910766
Familial prostate cancer	Uncertain significance	rs755391206	RCV005930680
Gastric cancer	Benign	rs77626845	RCV005910768
Hepatocellular carcinoma	Benign	rs77626845	RCV005910761
Lung cancer	Benign	rs77626845	RCV005910773
Malignant tumor of esophagus	Benign	rs77626845	RCV005910762
Nonpapillary renal cell carcinoma	Benign	rs77626845	RCV005910763
Ovarian serous cystadenocarcinoma	Benign	rs77626845	RCV005910769
Sarcoma	Benign	rs77626845	RCV005910767
Thymoma	Benign	rs77626845	RCV005910771
Thyroid cancer, nonmedullary, 1	Benign	rs77626845	RCV005910772
Uterine carcinosarcoma	Benign	rs77626845	RCV005910770
Uterine corpus endometrial carcinoma	Benign	rs77626845	RCV005910774

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	33878706
Carcinoma Hepatocellular	Associate	38305606
Leukemia Lymphoma Adult T Cell	Associate	3865189
Neoplasm Metastasis	Associate	26965286
Non alcoholic Fatty Liver Disease	Associate	38305606
Salivary Gland Neoplasms	Associate	33878706

ATL2 (atlastin GTPase 2)