Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6421
Gene name Gene Name - the full gene name approved by the HGNC.	Splicing factor proline and glutamine rich
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SFPQ
Synonyms (NCBI Gene) Gene synonyms aliases	POMP100, PPP1R140, PSF
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p34.3

Show/Hide all(297)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002310	hsa-miR-29b-3p	Immunoprecipitaion, Luciferase reporter assay, Western blot	17637574
MIRT002309	hsa-miR-141-3p	Immunoprecipitaion, Luciferase reporter assay, Western blot	17637574
MIRT047727	hsa-miR-10a-5p	CLASH	23622248
MIRT043279	hsa-miR-331-3p	CLASH	23622248
MIRT043279	hsa-miR-331-3p	CLASH	23622248
MIRT041361	hsa-miR-193b-3p	CLASH	23622248
MIRT040650	hsa-miR-92b-3p	CLASH	23622248
MIRT040035	hsa-miR-615-3p	CLASH	23622248
MIRT036338	hsa-miR-1229-3p	CLASH	23622248
MIRT554376	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT554375	hsa-miR-5694	PAR-CLIP	21572407
MIRT554374	hsa-miR-6895-5p	PAR-CLIP	21572407
MIRT554373	hsa-miR-7160-3p	PAR-CLIP	21572407
MIRT554372	hsa-miR-4512	PAR-CLIP	21572407
MIRT554371	hsa-miR-5697	PAR-CLIP	21572407
MIRT554370	hsa-miR-6508-3p	PAR-CLIP	21572407
MIRT554369	hsa-miR-1296-5p	PAR-CLIP	21572407
MIRT554368	hsa-miR-1297	PAR-CLIP	21572407
MIRT554367	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT554366	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT554365	hsa-miR-4465	PAR-CLIP	21572407
MIRT554364	hsa-miR-498	PAR-CLIP	21572407
MIRT439658	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439658	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT554376	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT554375	hsa-miR-5694	PAR-CLIP	21572407
MIRT554374	hsa-miR-6895-5p	PAR-CLIP	21572407
MIRT554373	hsa-miR-7160-3p	PAR-CLIP	21572407
MIRT554372	hsa-miR-4512	PAR-CLIP	21572407
MIRT554371	hsa-miR-5697	PAR-CLIP	21572407
MIRT554370	hsa-miR-6508-3p	PAR-CLIP	21572407
MIRT554369	hsa-miR-1296-5p	PAR-CLIP	21572407
MIRT554368	hsa-miR-1297	PAR-CLIP	21572407
MIRT554367	hsa-miR-26a-5p	PAR-CLIP	21572407
MIRT554366	hsa-miR-26b-5p	PAR-CLIP	21572407
MIRT554365	hsa-miR-4465	PAR-CLIP	21572407
MIRT554364	hsa-miR-498	PAR-CLIP	21572407
MIRT1341822	hsa-miR-101	CLIP-seq
MIRT1341823	hsa-miR-105	CLIP-seq
MIRT1341824	hsa-miR-1226	CLIP-seq
MIRT1341825	hsa-miR-1263	CLIP-seq
MIRT1341826	hsa-miR-127-5p	CLIP-seq
MIRT1341827	hsa-miR-1277	CLIP-seq
MIRT1341828	hsa-miR-1296	CLIP-seq
MIRT1341829	hsa-miR-1305	CLIP-seq
MIRT1341830	hsa-miR-141	CLIP-seq
MIRT1341831	hsa-miR-144	CLIP-seq
MIRT1341832	hsa-miR-153	CLIP-seq
MIRT1341833	hsa-miR-1976	CLIP-seq
MIRT1341834	hsa-miR-200a	CLIP-seq
MIRT1341835	hsa-miR-2110	CLIP-seq
MIRT1341836	hsa-miR-2115	CLIP-seq
MIRT1341837	hsa-miR-217	CLIP-seq
MIRT1341838	hsa-miR-26a	CLIP-seq
MIRT1341839	hsa-miR-26b	CLIP-seq
MIRT1341840	hsa-miR-29a	CLIP-seq
MIRT1341841	hsa-miR-29b	CLIP-seq
MIRT1341842	hsa-miR-29c	CLIP-seq
MIRT1341843	hsa-miR-300	CLIP-seq
MIRT1341844	hsa-miR-3065-5p	CLIP-seq
MIRT1341845	hsa-miR-3126-5p	CLIP-seq
MIRT1341846	hsa-miR-3158-3p	CLIP-seq
MIRT1341847	hsa-miR-3190	CLIP-seq
MIRT1341848	hsa-miR-3662	CLIP-seq
MIRT1341849	hsa-miR-3671	CLIP-seq
MIRT1341850	hsa-miR-3692	CLIP-seq
MIRT1341851	hsa-miR-381	CLIP-seq
MIRT1341852	hsa-miR-3978	CLIP-seq
MIRT1341853	hsa-miR-4271	CLIP-seq
MIRT1341854	hsa-miR-4276	CLIP-seq
MIRT1341855	hsa-miR-4419a	CLIP-seq
MIRT1341856	hsa-miR-4436b-5p	CLIP-seq
MIRT1341857	hsa-miR-4446-3p	CLIP-seq
MIRT1341858	hsa-miR-4457	CLIP-seq
MIRT1341859	hsa-miR-4491	CLIP-seq
MIRT1341860	hsa-miR-4495	CLIP-seq
MIRT1341861	hsa-miR-4510	CLIP-seq
MIRT1341862	hsa-miR-4517	CLIP-seq
MIRT1341863	hsa-miR-4528	CLIP-seq
MIRT1341864	hsa-miR-4657	CLIP-seq
MIRT1341865	hsa-miR-4698	CLIP-seq
MIRT1341866	hsa-miR-4725-3p	CLIP-seq
MIRT1341867	hsa-miR-4729	CLIP-seq
MIRT1341868	hsa-miR-4769-3p	CLIP-seq
MIRT1341869	hsa-miR-4775	CLIP-seq
MIRT1341870	hsa-miR-4789-5p	CLIP-seq
MIRT1341871	hsa-miR-511	CLIP-seq
MIRT1341872	hsa-miR-516a-3p	CLIP-seq
MIRT1341873	hsa-miR-520d-5p	CLIP-seq
MIRT1341874	hsa-miR-524-5p	CLIP-seq
MIRT1341875	hsa-miR-548ac	CLIP-seq
MIRT1341876	hsa-miR-548ae	CLIP-seq
MIRT1341877	hsa-miR-548aj	CLIP-seq
MIRT1341878	hsa-miR-548am	CLIP-seq
MIRT1341879	hsa-miR-548d-3p	CLIP-seq
MIRT1341880	hsa-miR-548n	CLIP-seq
MIRT1341881	hsa-miR-548t	CLIP-seq
MIRT1341882	hsa-miR-548x	CLIP-seq
MIRT1341883	hsa-miR-548z	CLIP-seq
MIRT1341884	hsa-miR-586	CLIP-seq
MIRT1341885	hsa-miR-590-3p	CLIP-seq
MIRT1341886	hsa-miR-600	CLIP-seq
MIRT1341887	hsa-miR-607	CLIP-seq
MIRT1341888	hsa-miR-624	CLIP-seq
MIRT1341889	hsa-miR-660	CLIP-seq
MIRT1341822	hsa-miR-101	CLIP-seq
MIRT2101193	hsa-miR-1200	CLIP-seq
MIRT1341825	hsa-miR-1263	CLIP-seq
MIRT1341827	hsa-miR-1277	CLIP-seq
MIRT1341828	hsa-miR-1296	CLIP-seq
MIRT1341830	hsa-miR-141	CLIP-seq
MIRT1341831	hsa-miR-144	CLIP-seq
MIRT1341833	hsa-miR-1976	CLIP-seq
MIRT1341834	hsa-miR-200a	CLIP-seq
MIRT1341837	hsa-miR-217	CLIP-seq
MIRT1341838	hsa-miR-26a	CLIP-seq
MIRT1341839	hsa-miR-26b	CLIP-seq
MIRT1341845	hsa-miR-3126-5p	CLIP-seq
MIRT2101194	hsa-miR-3140-5p	CLIP-seq
MIRT2101195	hsa-miR-3160-5p	CLIP-seq
MIRT1341847	hsa-miR-3190	CLIP-seq
MIRT1341850	hsa-miR-3692	CLIP-seq
MIRT2101196	hsa-miR-374c	CLIP-seq
MIRT1341852	hsa-miR-3978	CLIP-seq
MIRT1341854	hsa-miR-4276	CLIP-seq
MIRT2101197	hsa-miR-4279	CLIP-seq
MIRT2101198	hsa-miR-4305	CLIP-seq
MIRT1341855	hsa-miR-4419a	CLIP-seq
MIRT1341858	hsa-miR-4457	CLIP-seq
MIRT1341859	hsa-miR-4491	CLIP-seq
MIRT1341861	hsa-miR-4510	CLIP-seq
MIRT1341863	hsa-miR-4528	CLIP-seq
MIRT2101199	hsa-miR-4639-3p	CLIP-seq
MIRT1341864	hsa-miR-4657	CLIP-seq
MIRT2101200	hsa-miR-4699-5p	CLIP-seq
MIRT1341868	hsa-miR-4769-3p	CLIP-seq
MIRT1341869	hsa-miR-4775	CLIP-seq
MIRT1341870	hsa-miR-4789-5p	CLIP-seq
MIRT2101201	hsa-miR-582-5p	CLIP-seq
MIRT1341884	hsa-miR-586	CLIP-seq
MIRT1341885	hsa-miR-590-3p	CLIP-seq
MIRT1341888	hsa-miR-624	CLIP-seq
MIRT2101202	hsa-miR-655	CLIP-seq
MIRT1341889	hsa-miR-660	CLIP-seq
MIRT1341822	hsa-miR-101	CLIP-seq
MIRT2101193	hsa-miR-1200	CLIP-seq
MIRT1341824	hsa-miR-1226	CLIP-seq
MIRT1341825	hsa-miR-1263	CLIP-seq
MIRT1341827	hsa-miR-1277	CLIP-seq
MIRT1341828	hsa-miR-1296	CLIP-seq
MIRT1341829	hsa-miR-1305	CLIP-seq
MIRT1341830	hsa-miR-141	CLIP-seq
MIRT1341831	hsa-miR-144	CLIP-seq
MIRT1341833	hsa-miR-1976	CLIP-seq
MIRT1341834	hsa-miR-200a	CLIP-seq
MIRT1341836	hsa-miR-2115	CLIP-seq
MIRT1341837	hsa-miR-217	CLIP-seq
MIRT1341838	hsa-miR-26a	CLIP-seq
MIRT1341839	hsa-miR-26b	CLIP-seq
MIRT1341840	hsa-miR-29a	CLIP-seq
MIRT1341841	hsa-miR-29b	CLIP-seq
MIRT1341842	hsa-miR-29c	CLIP-seq
MIRT1341845	hsa-miR-3126-5p	CLIP-seq
MIRT2101194	hsa-miR-3140-5p	CLIP-seq
MIRT2101195	hsa-miR-3160-5p	CLIP-seq
MIRT1341847	hsa-miR-3190	CLIP-seq
MIRT2325571	hsa-miR-337-3p	CLIP-seq
MIRT1341848	hsa-miR-3662	CLIP-seq
MIRT1341850	hsa-miR-3692	CLIP-seq
MIRT2101196	hsa-miR-374c	CLIP-seq
MIRT1341852	hsa-miR-3978	CLIP-seq
MIRT1341854	hsa-miR-4276	CLIP-seq
MIRT2101197	hsa-miR-4279	CLIP-seq
MIRT2101198	hsa-miR-4305	CLIP-seq
MIRT1341855	hsa-miR-4419a	CLIP-seq
MIRT1341856	hsa-miR-4436b-5p	CLIP-seq
MIRT1341858	hsa-miR-4457	CLIP-seq
MIRT1341859	hsa-miR-4491	CLIP-seq
MIRT1341861	hsa-miR-4510	CLIP-seq
MIRT1341862	hsa-miR-4517	CLIP-seq
MIRT1341863	hsa-miR-4528	CLIP-seq
MIRT2101199	hsa-miR-4639-3p	CLIP-seq
MIRT1341864	hsa-miR-4657	CLIP-seq
MIRT2325572	hsa-miR-4659a-3p	CLIP-seq
MIRT2325573	hsa-miR-4659b-3p	CLIP-seq
MIRT2325574	hsa-miR-4662a-3p	CLIP-seq
MIRT1341865	hsa-miR-4698	CLIP-seq
MIRT2101200	hsa-miR-4699-5p	CLIP-seq
MIRT1341868	hsa-miR-4769-3p	CLIP-seq
MIRT1341869	hsa-miR-4775	CLIP-seq
MIRT2325575	hsa-miR-4778-3p	CLIP-seq
MIRT1341870	hsa-miR-4789-5p	CLIP-seq
MIRT1341871	hsa-miR-511	CLIP-seq
MIRT1341872	hsa-miR-516a-3p	CLIP-seq
MIRT1341873	hsa-miR-520d-5p	CLIP-seq
MIRT1341874	hsa-miR-524-5p	CLIP-seq
MIRT2325576	hsa-miR-548g	CLIP-seq
MIRT2101201	hsa-miR-582-5p	CLIP-seq
MIRT1341884	hsa-miR-586	CLIP-seq
MIRT1341885	hsa-miR-590-3p	CLIP-seq
MIRT1341886	hsa-miR-600	CLIP-seq
MIRT2325577	hsa-miR-606	CLIP-seq
MIRT1341887	hsa-miR-607	CLIP-seq
MIRT1341888	hsa-miR-624	CLIP-seq
MIRT2101202	hsa-miR-655	CLIP-seq
MIRT1341889	hsa-miR-660	CLIP-seq
MIRT2325578	hsa-miR-944	CLIP-seq
MIRT1341824	hsa-miR-1226	CLIP-seq
MIRT1341827	hsa-miR-1277	CLIP-seq
MIRT1341836	hsa-miR-2115	CLIP-seq
MIRT1341840	hsa-miR-29a	CLIP-seq
MIRT1341841	hsa-miR-29b	CLIP-seq
MIRT1341842	hsa-miR-29c	CLIP-seq
MIRT2101195	hsa-miR-3160-5p	CLIP-seq
MIRT1341847	hsa-miR-3190	CLIP-seq
MIRT2325571	hsa-miR-337-3p	CLIP-seq
MIRT1341854	hsa-miR-4276	CLIP-seq
MIRT1341859	hsa-miR-4491	CLIP-seq
MIRT1341862	hsa-miR-4517	CLIP-seq
MIRT2101199	hsa-miR-4639-3p	CLIP-seq
MIRT1341864	hsa-miR-4657	CLIP-seq
MIRT1341872	hsa-miR-516a-3p	CLIP-seq
MIRT1341835	hsa-miR-2110	CLIP-seq
MIRT1341853	hsa-miR-4271	CLIP-seq
MIRT1341866	hsa-miR-4725-3p	CLIP-seq
MIRT1341875	hsa-miR-548ac	CLIP-seq
MIRT1341876	hsa-miR-548ae	CLIP-seq
MIRT1341877	hsa-miR-548aj	CLIP-seq
MIRT1341878	hsa-miR-548am	CLIP-seq
MIRT1341879	hsa-miR-548d-3p	CLIP-seq
MIRT1341882	hsa-miR-548x	CLIP-seq
MIRT1341883	hsa-miR-548z	CLIP-seq
MIRT1341835	hsa-miR-2110	CLIP-seq
MIRT1341853	hsa-miR-4271	CLIP-seq
MIRT1341866	hsa-miR-4725-3p	CLIP-seq
MIRT1341875	hsa-miR-548ac	CLIP-seq
MIRT1341876	hsa-miR-548ae	CLIP-seq
MIRT1341877	hsa-miR-548aj	CLIP-seq
MIRT1341878	hsa-miR-548am	CLIP-seq
MIRT1341879	hsa-miR-548d-3p	CLIP-seq
MIRT1341882	hsa-miR-548x	CLIP-seq
MIRT1341883	hsa-miR-548z	CLIP-seq
MIRT2101193	hsa-miR-1200	CLIP-seq
MIRT1341824	hsa-miR-1226	CLIP-seq
MIRT1341835	hsa-miR-2110	CLIP-seq
MIRT1341836	hsa-miR-2115	CLIP-seq
MIRT1341840	hsa-miR-29a	CLIP-seq
MIRT1341841	hsa-miR-29b	CLIP-seq
MIRT1341842	hsa-miR-29c	CLIP-seq
MIRT2101194	hsa-miR-3140-5p	CLIP-seq
MIRT2325571	hsa-miR-337-3p	CLIP-seq
MIRT1341850	hsa-miR-3692	CLIP-seq
MIRT2101196	hsa-miR-374c	CLIP-seq
MIRT1341853	hsa-miR-4271	CLIP-seq
MIRT2325572	hsa-miR-4659a-3p	CLIP-seq
MIRT2325573	hsa-miR-4659b-3p	CLIP-seq
MIRT2101200	hsa-miR-4699-5p	CLIP-seq
MIRT1341866	hsa-miR-4725-3p	CLIP-seq
MIRT1341872	hsa-miR-516a-3p	CLIP-seq
MIRT1341875	hsa-miR-548ac	CLIP-seq
MIRT1341876	hsa-miR-548ae	CLIP-seq
MIRT1341877	hsa-miR-548aj	CLIP-seq
MIRT1341878	hsa-miR-548am	CLIP-seq
MIRT1341879	hsa-miR-548d-3p	CLIP-seq
MIRT1341882	hsa-miR-548x	CLIP-seq
MIRT1341883	hsa-miR-548z	CLIP-seq
MIRT2101201	hsa-miR-582-5p	CLIP-seq
MIRT1341884	hsa-miR-586	CLIP-seq
MIRT2325577	hsa-miR-606	CLIP-seq
MIRT2101202	hsa-miR-655	CLIP-seq
MIRT1341889	hsa-miR-660	CLIP-seq
MIRT2101193	hsa-miR-1200	CLIP-seq
MIRT1341824	hsa-miR-1226	CLIP-seq
MIRT1341835	hsa-miR-2110	CLIP-seq
MIRT1341836	hsa-miR-2115	CLIP-seq
MIRT1341840	hsa-miR-29a	CLIP-seq
MIRT1341841	hsa-miR-29b	CLIP-seq
MIRT1341842	hsa-miR-29c	CLIP-seq
MIRT2101194	hsa-miR-3140-5p	CLIP-seq
MIRT2325571	hsa-miR-337-3p	CLIP-seq
MIRT1341850	hsa-miR-3692	CLIP-seq
MIRT2101196	hsa-miR-374c	CLIP-seq
MIRT1341853	hsa-miR-4271	CLIP-seq
MIRT2101200	hsa-miR-4699-5p	CLIP-seq
MIRT1341866	hsa-miR-4725-3p	CLIP-seq
MIRT1341872	hsa-miR-516a-3p	CLIP-seq
MIRT1341875	hsa-miR-548ac	CLIP-seq
MIRT1341876	hsa-miR-548ae	CLIP-seq
MIRT1341877	hsa-miR-548aj	CLIP-seq
MIRT1341878	hsa-miR-548am	CLIP-seq
MIRT1341879	hsa-miR-548d-3p	CLIP-seq
MIRT1341882	hsa-miR-548x	CLIP-seq
MIRT1341883	hsa-miR-548z	CLIP-seq
MIRT2101201	hsa-miR-582-5p	CLIP-seq
MIRT2325577	hsa-miR-606	CLIP-seq
MIRT2101202	hsa-miR-655	CLIP-seq
MIRT1341889	hsa-miR-660	CLIP-seq

Show/Hide all(40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	16731528
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IGI	15790595
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IMP	22783022
GO:0000380	Process	Alternative mRNA splicing, via spliceosome	IBA	21873635
GO:0000380	Process	Alternative mRNA splicing, via spliceosome	IMP	19874820
GO:0000398	Process	MRNA splicing, via spliceosome	IBA	21873635
GO:0000724	Process	Double-strand break repair via homologous recombination	IMP	20813759
GO:0000785	Component	Chromatin	IDA	16731528
GO:0000976	Function	Transcription regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000976	Function	Transcription regulatory region sequence-specific DNA binding	ISS
GO:0002218	Process	Activation of innate immune response	IDA	28712728
GO:0003676	Function	Nucleic acid binding	IBA	21873635
GO:0003677	Function	DNA binding	IDA	25765647
GO:0003682	Function	Chromatin binding	ISS
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	9848648, 10653975, 11259580, 11514619, 15790595, 16417406, 16731528, 18457437, 19439179, 19874820, 20932480, 21988832, 23714182, 25765647, 25959826, 26030138, 28514442, 30021884
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	15790595
GO:0005654	Component	Nucleoplasm	IDA	19874820
GO:0005654	Component	Nucleoplasm	TAS
GO:0006355	Process	Regulation of transcription, DNA-templated	IBA	21873635
GO:0006397	Process	MRNA processing	TAS	8449401
GO:0008380	Process	RNA splicing	TAS	8449401
GO:0016363	Component	Nuclear matrix	IDA	19874820
GO:0016607	Component	Nuclear speck	IEA
GO:0032839	Component	Dendrite cytoplasm	IEA
GO:0042382	Component	Paraspeckles	IDA	19874820, 25765647
GO:0042752	Process	Regulation of circadian rhythm	ISS
GO:0042754	Process	Negative regulation of circadian rhythm	ISS
GO:0042803	Function	Protein homodimerization activity	IPI	25765647
GO:0042826	Function	Histone deacetylase binding	IPI	16731528
GO:0045087	Process	Innate immune response	IEA
GO:0045876	Process	Positive regulation of sister chromatid cohesion	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	25765647
GO:0048511	Process	Rhythmic process	IEA
GO:0070932	Process	Histone H3 deacetylation	ISS
GO:0090575	Component	RNA polymerase II transcription regulator complex	ISS
GO:0098963	Process	Dendritic transport of messenger ribonucleoprotein complex	IEA
GO:1902177	Process	Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	IDA	15790595

MIM	HGNC	e!Ensembl
605199	10774	ENSG00000116560

Protein

UniProt ID

P23246

Protein name

Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)

Protein function

DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceoso

PDB

4WII , 4WIJ , 4WIK , 5WPA , 6NCQ , 6OWJ , 6WMZ , 7LRQ , 7LRU , 7PU5 , 7SP0 , 7UJ1 , 7UK1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	299 → 363	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	373 → 440	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF08075	NOPS	444 → 495	NOPS (NUC059) domain	Domain

Sequence

MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI
PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG
VGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ
AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE
PRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLF
VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGR
QLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFAS
KPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRF
AQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLM
RRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRM
GYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGS
DMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF

Sequence length

707

Interactions

View interactions

	Reactome
			PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Renal carcinoma	MiT family translocation renal cell carcinoma	rs121913668, rs121913670, rs121913243, rs786202724	20073616, 9393982

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Schizophrenia	Schizophrenia			GWAS

Show/Hide Text Mining Associations (29)

Disease Name	Relationship Type	References
Associations from Text Mining
Amyotrophic Lateral Sclerosis	Associate	33495278, 33693641, 36168806
Amyotrophic lateral sclerosis 1	Associate	36168806
Breast Neoplasms	Associate	33017027
Calcinosis	Associate	29713041
Carcinoma Hepatocellular	Associate	37324188
Carcinoma Non Small Cell Lung	Stimulate	37569873
Carcinoma Non Small Cell Lung	Associate	37960731
Carcinoma Renal Cell	Associate	26975036, 30951404
Colorectal Neoplasms	Associate	24288667, 38166604
Cystic Disease Of Lung	Associate	34404863
Cystic Fibrosis	Inhibit	34404863
Dyslexia	Associate	18445785
Fanconi Anemia	Associate	31990679
Frontotemporal Dementia	Associate	33495278
Hematologic Neoplasms	Associate	24327337
Inflammation	Associate	37569873
Leukemia	Associate	24327337
Leukemia Myeloid Acute	Associate	22976956, 31990679
Lung Diseases	Associate	34404863
Malignant mesenchymal tumor	Associate	32889887
Melanoma	Associate	34218270
Neoplasms	Associate	26975036, 32146802, 32889887, 34218270, 37569873, 38103553
Neurologic Manifestations	Associate	36168806
Osteoarthritis	Inhibit	36915153
Perivascular Epithelioid Cell Neoplasms	Associate	32146802
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	35061886
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	35974102
Prostatic Neoplasms	Associate	23737958
Triple Negative Breast Neoplasms	Associate	30725116

SFPQ (splicing factor proline and glutamine rich)