Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	641649
Gene name	Transmembrane protein 91
Gene symbol	TMEM91
Synonyms (NCBI Gene)	DSPC3IFITMD6SynDIG3
Chromosome	19
Chromosome location	19q13.2

137

Show/Hide all (137)

miRTarBase ID	miRNA	Experiments	Reference
MIRT676228	hsa-miR-4426	HITS-CLIP	23824327
MIRT676227	hsa-miR-4647	HITS-CLIP	23824327
MIRT676226	hsa-miR-4662b	HITS-CLIP	23824327
MIRT676225	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT676224	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT676223	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT676222	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT676221	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT676220	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT676219	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT676218	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT676217	hsa-miR-7977	HITS-CLIP	23824327
MIRT676216	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT676215	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT676214	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT676213	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT676212	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT676211	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT676210	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT676209	hsa-miR-3689c	HITS-CLIP	23824327
MIRT676208	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT676207	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT676206	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT676205	hsa-miR-3122	HITS-CLIP	23824327
MIRT676204	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT676203	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT676202	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT465815	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT465814	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT465813	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT465812	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT465811	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT465810	hsa-miR-4446-3p	PAR-CLIP	23592263
MIRT465809	hsa-miR-4688	PAR-CLIP	23592263
MIRT465807	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT465808	hsa-miR-6085	PAR-CLIP	23592263
MIRT465806	hsa-miR-6813-5p	PAR-CLIP	23592263
MIRT465805	hsa-miR-6823-5p	PAR-CLIP	23592263
MIRT465804	hsa-miR-1266-5p	PAR-CLIP	23592263
MIRT465803	hsa-miR-4518	PAR-CLIP	23592263
MIRT465802	hsa-miR-378g	PAR-CLIP	23592263
MIRT465801	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT465800	hsa-miR-4721	PAR-CLIP	23592263
MIRT465799	hsa-miR-4656	PAR-CLIP	23592263
MIRT465798	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT465797	hsa-miR-4492	PAR-CLIP	23592263
MIRT465796	hsa-miR-4498	PAR-CLIP	23592263
MIRT465795	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT465794	hsa-miR-762	PAR-CLIP	23592263
MIRT465793	hsa-miR-4675	PAR-CLIP	23592263
MIRT465792	hsa-miR-4741	PAR-CLIP	23592263
MIRT465791	hsa-miR-6789-5p	PAR-CLIP	23592263
MIRT465790	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT465789	hsa-miR-1226-5p	PAR-CLIP	23592263
MIRT465788	hsa-miR-1587	PAR-CLIP	23592263
MIRT465787	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT465786	hsa-miR-135b-3p	PAR-CLIP	23592263
MIRT676228	hsa-miR-4426	HITS-CLIP	23824327
MIRT676227	hsa-miR-4647	HITS-CLIP	23824327
MIRT676226	hsa-miR-4662b	HITS-CLIP	23824327
MIRT676225	hsa-miR-6871-5p	HITS-CLIP	23824327
MIRT676224	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT676223	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT676222	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT676221	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT676220	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT676219	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT676218	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT676217	hsa-miR-7977	HITS-CLIP	23824327
MIRT676216	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT676215	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT676214	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT676213	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT676212	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT676211	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT676210	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT676209	hsa-miR-3689c	HITS-CLIP	23824327
MIRT676208	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT676207	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT676206	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT676205	hsa-miR-3122	HITS-CLIP	23824327
MIRT676204	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT676203	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT676202	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT465815	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT465814	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT465813	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT465812	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT465811	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT465810	hsa-miR-4446-3p	PAR-CLIP	23592263
MIRT465809	hsa-miR-4688	PAR-CLIP	23592263
MIRT465807	hsa-miR-6743-5p	PAR-CLIP	23592263
MIRT465808	hsa-miR-6085	PAR-CLIP	23592263
MIRT465806	hsa-miR-6813-5p	PAR-CLIP	23592263
MIRT465805	hsa-miR-6823-5p	PAR-CLIP	23592263
MIRT465804	hsa-miR-1266-5p	PAR-CLIP	23592263
MIRT465803	hsa-miR-4518	PAR-CLIP	23592263
MIRT465802	hsa-miR-378g	PAR-CLIP	23592263
MIRT465801	hsa-miR-3616-3p	PAR-CLIP	23592263
MIRT465800	hsa-miR-4721	PAR-CLIP	23592263
MIRT465799	hsa-miR-4656	PAR-CLIP	23592263
MIRT465798	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT465797	hsa-miR-4492	PAR-CLIP	23592263
MIRT465796	hsa-miR-4498	PAR-CLIP	23592263
MIRT465795	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT465794	hsa-miR-762	PAR-CLIP	23592263
MIRT465793	hsa-miR-4675	PAR-CLIP	23592263
MIRT465792	hsa-miR-4741	PAR-CLIP	23592263
MIRT465791	hsa-miR-6789-5p	PAR-CLIP	23592263
MIRT465790	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT465789	hsa-miR-1226-5p	PAR-CLIP	23592263
MIRT465788	hsa-miR-1587	PAR-CLIP	23592263
MIRT465787	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT465786	hsa-miR-135b-3p	PAR-CLIP	23592263
MIRT1439596	hsa-miR-4519	CLIP-seq
MIRT1439597	hsa-miR-4645-5p	CLIP-seq
MIRT1439598	hsa-miR-4673	CLIP-seq
MIRT1439599	hsa-miR-1976	CLIP-seq
MIRT1439600	hsa-miR-4268	CLIP-seq
MIRT1439601	hsa-miR-4448	CLIP-seq
MIRT1439602	hsa-miR-4632	CLIP-seq
MIRT1439603	hsa-miR-4722-3p	CLIP-seq
MIRT1439604	hsa-miR-4777-5p	CLIP-seq
MIRT2646481	hsa-miR-2682	CLIP-seq
MIRT2646482	hsa-miR-34a	CLIP-seq
MIRT2646483	hsa-miR-34c-5p	CLIP-seq
MIRT2646484	hsa-miR-449a	CLIP-seq
MIRT2646485	hsa-miR-449b	CLIP-seq
MIRT2646486	hsa-miR-449c	CLIP-seq
MIRT1439596	hsa-miR-4519	CLIP-seq
MIRT2646481	hsa-miR-2682	CLIP-seq
MIRT2646482	hsa-miR-34a	CLIP-seq
MIRT2646483	hsa-miR-34c-5p	CLIP-seq
MIRT2646484	hsa-miR-449a	CLIP-seq
MIRT2646485	hsa-miR-449b	CLIP-seq
MIRT2646486	hsa-miR-449c	CLIP-seq
MIRT1439596	hsa-miR-4519	CLIP-seq

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002244	Process	Hematopoietic progenitor cell differentiation	IEA
GO:0003674	Function	Molecular_function	ND
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005575	Component	Cellular_component	ND
GO:0008150	Process	Biological_process	ND
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IBA

MIM	HGNC	e!Ensembl
618294	32393	ENSG00000142046

Q6ZNR0

Protein name

Transmembrane protein 91 (Dispanin subfamily C member 3) (DSPC3)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04505	CD225	91 → 158	Interferon-induced transmembrane protein	Family

Sequence

MDSPSLRELQQPLLEGTECETPAQKPGRHELGSPLREIAFAESLRGLQFLSPPLPSVSAG
LGEPRPPDVEDMSSSDSDSDWDGGSRLSPFLPHDHLGLAVFSMLCCFWPVGIAAFCLAQK
TNKAWAKGDIQGAGAASRRAFLLGVLAVGLGVCTYAAALVTLAAYLASRDPP

Sequence length

172

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATRIAL FIBRILLATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL ADENOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Asthma	Associate	22053598	★★★★★ ★☆☆☆☆ Found in Text Mining only
Corneal Perforation	Associate	26670709	★★★★★ ★☆☆☆☆ Found in Text Mining only
COVID 19	Associate	38327202	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cystic Fibrosis	Associate	18424453	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cystitis Interstitial	Associate	30973927	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Associate	26579581	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Foot	Associate	26579581	★★★★★ ★☆☆☆☆ Found in Text Mining only
Emphysema	Associate	18670143	★★★★★ ★☆☆☆☆ Found in Text Mining only
Enterocolitis Necrotizing	Associate	26670709	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Associate	18670143, 23267696	★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Insufficiency Chronic	Associate	26579581	★★★★★ ★☆☆☆☆ Found in Text Mining only

TMEM91 (transmembrane protein 91)