Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6416
Gene name Gene Name - the full gene name approved by the HGNC.	Mitogen-activated protein kinase kinase 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MAP2K4
Synonyms (NCBI Gene) Gene synonyms aliases	JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17p12
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, different

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019756	hsa-miR-375	Microarray	20215506
MIRT028937	hsa-miR-26b-5p	Microarray	19088304
MIRT023483	hsa-miR-15b-5p	CLASH	23622248
MIRT053655	hsa-miR-145-5p	Microarray	22942087
MIRT053698	hsa-miR-188-5p	Microarray	22942087
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	24556602
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	24556602
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	24556602
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, Western blot	24556602
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT437965	hsa-miR-92a-3p	qRT-PCR, Luciferase reporter assay, Western blot	24705900
MIRT556342	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT556341	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT437965	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT556340	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT556339	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT030360	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT556338	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT556337	hsa-miR-548ab	PAR-CLIP	21572407
MIRT556336	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT556335	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT556334	hsa-miR-548ak	PAR-CLIP	21572407
MIRT556333	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT556332	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT556331	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT556330	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT556329	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT556328	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT556327	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT556326	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT556325	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT556324	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT556323	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT556322	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT556321	hsa-miR-548i	PAR-CLIP	21572407
MIRT556320	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT556319	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT556318	hsa-miR-548w	PAR-CLIP	21572407
MIRT556317	hsa-miR-548y	PAR-CLIP	21572407
MIRT556316	hsa-miR-559	PAR-CLIP	21572407
MIRT556315	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT556314	hsa-miR-3614-5p	PAR-CLIP	21572407
MIRT556313	hsa-miR-5193	PAR-CLIP	21572407
MIRT556312	hsa-miR-660-3p	PAR-CLIP	21572407
MIRT556311	hsa-miR-3121-5p	PAR-CLIP	21572407
MIRT556310	hsa-miR-3185	PAR-CLIP	21572407
MIRT556309	hsa-miR-4691-5p	PAR-CLIP	21572407
MIRT556308	hsa-miR-6792-3p	PAR-CLIP	21572407
MIRT556307	hsa-miR-6749-3p	PAR-CLIP	21572407
MIRT556306	hsa-miR-7703	PAR-CLIP	21572407
MIRT556305	hsa-miR-4325	PAR-CLIP	21572407
MIRT556304	hsa-miR-7855-5p	PAR-CLIP	21572407
MIRT556303	hsa-miR-6818-3p	PAR-CLIP	21572407
MIRT473860	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT473859	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT473858	hsa-miR-4534	PAR-CLIP	23592263
MIRT473857	hsa-miR-8082	PAR-CLIP	23592263
MIRT473856	hsa-miR-3134	PAR-CLIP	23592263
MIRT473855	hsa-miR-4261	PAR-CLIP	23592263
MIRT473854	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT473853	hsa-let-7f-2-3p	PAR-CLIP	23592263
MIRT473852	hsa-miR-1185-1-3p	PAR-CLIP	23592263
MIRT473851	hsa-miR-1185-2-3p	PAR-CLIP	23592263
MIRT030360	hsa-miR-25-3p	Western blot	27353001
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	27594411
MIRT054442	hsa-miR-27a-3p	Luciferase reporter assay, qRT-PCR, Western blot	27594411
MIRT736251	hsa-miR-200a-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry, Immunocytochemistry (ICC)	32016794
MIRT737290	hsa-miR-512-3p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	32850377
MIRT556342	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT556341	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT437965	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT556340	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT556339	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT030360	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT556338	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT556337	hsa-miR-548ab	PAR-CLIP	21572407
MIRT556336	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT556335	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT556334	hsa-miR-548ak	PAR-CLIP	21572407
MIRT556333	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT556332	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT556331	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT556330	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT556329	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT556328	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT556327	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT556326	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT556325	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT556324	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT556323	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT556322	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT556321	hsa-miR-548i	PAR-CLIP	21572407
MIRT556320	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT556319	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT556318	hsa-miR-548w	PAR-CLIP	21572407
MIRT556317	hsa-miR-548y	PAR-CLIP	21572407
MIRT556316	hsa-miR-559	PAR-CLIP	21572407
MIRT556315	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT556314	hsa-miR-3614-5p	PAR-CLIP	21572407
MIRT556313	hsa-miR-5193	PAR-CLIP	21572407
MIRT556312	hsa-miR-660-3p	PAR-CLIP	21572407
MIRT556311	hsa-miR-3121-5p	PAR-CLIP	21572407
MIRT556310	hsa-miR-3185	PAR-CLIP	21572407
MIRT556309	hsa-miR-4691-5p	PAR-CLIP	21572407
MIRT556308	hsa-miR-6792-3p	PAR-CLIP	21572407
MIRT556307	hsa-miR-6749-3p	PAR-CLIP	21572407
MIRT556306	hsa-miR-7703	PAR-CLIP	21572407
MIRT556305	hsa-miR-4325	PAR-CLIP	21572407
MIRT556304	hsa-miR-7855-5p	PAR-CLIP	21572407
MIRT556303	hsa-miR-6818-3p	PAR-CLIP	21572407
MIRT473860	hsa-miR-3688-3p	PAR-CLIP	23592263
MIRT473859	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT473858	hsa-miR-4534	PAR-CLIP	23592263
MIRT473857	hsa-miR-8082	PAR-CLIP	23592263
MIRT473856	hsa-miR-3134	PAR-CLIP	23592263
MIRT473855	hsa-miR-4261	PAR-CLIP	23592263
MIRT473854	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT473853	hsa-let-7f-2-3p	PAR-CLIP	23592263
MIRT473852	hsa-miR-1185-1-3p	PAR-CLIP	23592263
MIRT473851	hsa-miR-1185-2-3p	PAR-CLIP	23592263
MIRT1128003	hsa-miR-1231	CLIP-seq
MIRT1128004	hsa-miR-1255a	CLIP-seq
MIRT1128005	hsa-miR-1255b	CLIP-seq
MIRT1128006	hsa-miR-125a-3p	CLIP-seq
MIRT1128007	hsa-miR-1266	CLIP-seq
MIRT1128008	hsa-miR-1273c	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128010	hsa-miR-1284	CLIP-seq
MIRT1128011	hsa-miR-1285	CLIP-seq
MIRT1128012	hsa-miR-129-3p	CLIP-seq
MIRT1128013	hsa-miR-134	CLIP-seq
MIRT1128014	hsa-miR-137	CLIP-seq
MIRT1128015	hsa-miR-140-3p	CLIP-seq
MIRT1128016	hsa-miR-15a	CLIP-seq
MIRT1128017	hsa-miR-15b	CLIP-seq
MIRT1128018	hsa-miR-16	CLIP-seq
MIRT1128019	hsa-miR-195	CLIP-seq
MIRT1128020	hsa-miR-1972	CLIP-seq
MIRT1128021	hsa-miR-2115	CLIP-seq
MIRT1128022	hsa-miR-2276	CLIP-seq
MIRT1128023	hsa-miR-2278	CLIP-seq
MIRT1128024	hsa-miR-25	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT1128027	hsa-miR-3065-5p	CLIP-seq
MIRT1128028	hsa-miR-3118	CLIP-seq
MIRT1128029	hsa-miR-3164	CLIP-seq
MIRT1128030	hsa-miR-3171	CLIP-seq
MIRT1128031	hsa-miR-3183	CLIP-seq
MIRT1128032	hsa-miR-3187-5p	CLIP-seq
MIRT1128033	hsa-miR-32	CLIP-seq
MIRT1128034	hsa-miR-3202	CLIP-seq
MIRT1128035	hsa-miR-34b	CLIP-seq
MIRT1128036	hsa-miR-3591-3p	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT1128038	hsa-miR-3611	CLIP-seq
MIRT1128039	hsa-miR-3622a-3p	CLIP-seq
MIRT1128040	hsa-miR-3622b-3p	CLIP-seq
MIRT1128041	hsa-miR-363	CLIP-seq
MIRT1128042	hsa-miR-3664-3p	CLIP-seq
MIRT1128043	hsa-miR-3665	CLIP-seq
MIRT1128044	hsa-miR-367	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT1128046	hsa-miR-369-3p	CLIP-seq
MIRT1128047	hsa-miR-374a	CLIP-seq
MIRT1128048	hsa-miR-374b	CLIP-seq
MIRT1128049	hsa-miR-378g	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT1128051	hsa-miR-3977	CLIP-seq
MIRT1128052	hsa-miR-424	CLIP-seq
MIRT1128053	hsa-miR-4256	CLIP-seq
MIRT1128054	hsa-miR-4271	CLIP-seq
MIRT1128055	hsa-miR-431	CLIP-seq
MIRT1128056	hsa-miR-4452	CLIP-seq
MIRT1128057	hsa-miR-4486	CLIP-seq
MIRT1128058	hsa-miR-4501	CLIP-seq
MIRT1128059	hsa-miR-4502	CLIP-seq
MIRT1128060	hsa-miR-4518	CLIP-seq
MIRT1128061	hsa-miR-4524	CLIP-seq
MIRT1128062	hsa-miR-4642	CLIP-seq
MIRT1128063	hsa-miR-4649-5p	CLIP-seq
MIRT1128064	hsa-miR-4650-5p	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT740154	hsa-miR-4678	CLIP-seq
MIRT1128066	hsa-miR-4690-3p	CLIP-seq
MIRT1128067	hsa-miR-4690-5p	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT1128068	hsa-miR-4717-3p	CLIP-seq
MIRT1128069	hsa-miR-4723-3p	CLIP-seq
MIRT1128070	hsa-miR-4725-3p	CLIP-seq
MIRT1128071	hsa-miR-4747-5p	CLIP-seq
MIRT1128072	hsa-miR-4764-5p	CLIP-seq
MIRT1128073	hsa-miR-4772-3p	CLIP-seq
MIRT1128074	hsa-miR-4777-5p	CLIP-seq
MIRT1128075	hsa-miR-4789-5p	CLIP-seq
MIRT1128076	hsa-miR-497	CLIP-seq
MIRT1128077	hsa-miR-503	CLIP-seq
MIRT1128078	hsa-miR-505	CLIP-seq
MIRT1128079	hsa-miR-5095	CLIP-seq
MIRT1128080	hsa-miR-513a-5p	CLIP-seq
MIRT1128081	hsa-miR-516a-3p	CLIP-seq
MIRT1128082	hsa-miR-518d-5p	CLIP-seq
MIRT1128083	hsa-miR-519b-5p	CLIP-seq
MIRT1128084	hsa-miR-519c-5p	CLIP-seq
MIRT1128085	hsa-miR-520c-5p	CLIP-seq
MIRT1128086	hsa-miR-526a	CLIP-seq
MIRT1128087	hsa-miR-544	CLIP-seq
MIRT1128088	hsa-miR-612	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT1128089	hsa-miR-646	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT1128091	hsa-miR-758	CLIP-seq
MIRT1128092	hsa-miR-92a	CLIP-seq
MIRT1128093	hsa-miR-92b	CLIP-seq
MIRT1556631	hsa-miR-1302	CLIP-seq
MIRT1556632	hsa-miR-22	CLIP-seq
MIRT1556633	hsa-miR-221	CLIP-seq
MIRT1556634	hsa-miR-222	CLIP-seq
MIRT1556635	hsa-miR-3122	CLIP-seq
MIRT1556636	hsa-miR-3649	CLIP-seq
MIRT1556637	hsa-miR-382	CLIP-seq
MIRT1556638	hsa-miR-3913-5p	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT1556639	hsa-miR-4298	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT1556640	hsa-miR-548v	CLIP-seq
MIRT2036387	hsa-miR-1227	CLIP-seq
MIRT2036388	hsa-miR-1229	CLIP-seq
MIRT1128007	hsa-miR-1266	CLIP-seq
MIRT1128008	hsa-miR-1273c	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128012	hsa-miR-129-3p	CLIP-seq
MIRT1128015	hsa-miR-140-3p	CLIP-seq
MIRT2036389	hsa-miR-145	CLIP-seq
MIRT2036390	hsa-miR-150	CLIP-seq
MIRT1128020	hsa-miR-1972	CLIP-seq
MIRT1128021	hsa-miR-2115	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT2036391	hsa-miR-299-3p	CLIP-seq
MIRT2036392	hsa-miR-3120-3p	CLIP-seq
MIRT2036393	hsa-miR-3150b-3p	CLIP-seq
MIRT1128031	hsa-miR-3183	CLIP-seq
MIRT1128034	hsa-miR-3202	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT1128039	hsa-miR-3622a-3p	CLIP-seq
MIRT1128040	hsa-miR-3622b-3p	CLIP-seq
MIRT2036394	hsa-miR-3647-3p	CLIP-seq
MIRT1128042	hsa-miR-3664-3p	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT2036395	hsa-miR-3942-5p	CLIP-seq
MIRT1128051	hsa-miR-3977	CLIP-seq
MIRT2036396	hsa-miR-4251	CLIP-seq
MIRT2036397	hsa-miR-4267	CLIP-seq
MIRT1128054	hsa-miR-4271	CLIP-seq
MIRT1128055	hsa-miR-431	CLIP-seq
MIRT2036398	hsa-miR-4329	CLIP-seq
MIRT2036399	hsa-miR-4491	CLIP-seq
MIRT1128060	hsa-miR-4518	CLIP-seq
MIRT2036400	hsa-miR-452	CLIP-seq
MIRT2036401	hsa-miR-4639-3p	CLIP-seq
MIRT1128062	hsa-miR-4642	CLIP-seq
MIRT1128064	hsa-miR-4650-5p	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT2036402	hsa-miR-4657	CLIP-seq
MIRT2036403	hsa-miR-4676-3p	CLIP-seq
MIRT2036404	hsa-miR-4681	CLIP-seq
MIRT1128066	hsa-miR-4690-3p	CLIP-seq
MIRT2036405	hsa-miR-4703-5p	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT2036406	hsa-miR-4713-5p	CLIP-seq
MIRT2036407	hsa-miR-4714-5p	CLIP-seq
MIRT1128069	hsa-miR-4723-3p	CLIP-seq
MIRT1128070	hsa-miR-4725-3p	CLIP-seq
MIRT1128071	hsa-miR-4747-5p	CLIP-seq
MIRT2036408	hsa-miR-4784	CLIP-seq
MIRT1128081	hsa-miR-516a-3p	CLIP-seq
MIRT2036409	hsa-miR-532-3p	CLIP-seq
MIRT2036410	hsa-miR-548h	CLIP-seq
MIRT2036411	hsa-miR-548j	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT2036412	hsa-miR-668	CLIP-seq
MIRT2036413	hsa-miR-887	CLIP-seq
MIRT2036414	hsa-miR-892a	CLIP-seq
MIRT2036415	hsa-miR-942	CLIP-seq
MIRT2036416	hsa-miR-943	CLIP-seq
MIRT2266617	hsa-miR-1205	CLIP-seq
MIRT2036387	hsa-miR-1227	CLIP-seq
MIRT1128003	hsa-miR-1231	CLIP-seq
MIRT2266618	hsa-miR-124	CLIP-seq
MIRT2266619	hsa-miR-127-3p	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128010	hsa-miR-1284	CLIP-seq
MIRT1128011	hsa-miR-1285	CLIP-seq
MIRT2266620	hsa-miR-136	CLIP-seq
MIRT2266621	hsa-miR-141	CLIP-seq
MIRT2036389	hsa-miR-145	CLIP-seq
MIRT2266622	hsa-miR-200a	CLIP-seq
MIRT2266623	hsa-miR-204	CLIP-seq
MIRT2266624	hsa-miR-211	CLIP-seq
MIRT1128024	hsa-miR-25	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT2266625	hsa-miR-29a	CLIP-seq
MIRT2266626	hsa-miR-29b	CLIP-seq
MIRT2266627	hsa-miR-29c	CLIP-seq
MIRT2266628	hsa-miR-3065-3p	CLIP-seq
MIRT1128027	hsa-miR-3065-5p	CLIP-seq
MIRT2036392	hsa-miR-3120-3p	CLIP-seq
MIRT2036393	hsa-miR-3150b-3p	CLIP-seq
MIRT2266629	hsa-miR-3161	CLIP-seq
MIRT1128032	hsa-miR-3187-5p	CLIP-seq
MIRT1128033	hsa-miR-32	CLIP-seq
MIRT1128035	hsa-miR-34b	CLIP-seq
MIRT1128036	hsa-miR-3591-3p	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT1128038	hsa-miR-3611	CLIP-seq
MIRT2266630	hsa-miR-3619-3p	CLIP-seq
MIRT1128041	hsa-miR-363	CLIP-seq
MIRT2266631	hsa-miR-3660	CLIP-seq
MIRT2266632	hsa-miR-3661	CLIP-seq
MIRT2266633	hsa-miR-3663-5p	CLIP-seq
MIRT1128044	hsa-miR-367	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT2266634	hsa-miR-3690	CLIP-seq
MIRT2266635	hsa-miR-3692	CLIP-seq
MIRT1128049	hsa-miR-378g	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT2036395	hsa-miR-3942-5p	CLIP-seq
MIRT2266636	hsa-miR-409-3p	CLIP-seq
MIRT2036396	hsa-miR-4251	CLIP-seq
MIRT2266637	hsa-miR-4254	CLIP-seq
MIRT1128053	hsa-miR-4256	CLIP-seq
MIRT2266638	hsa-miR-4287	CLIP-seq
MIRT2036398	hsa-miR-4329	CLIP-seq
MIRT2266639	hsa-miR-433	CLIP-seq
MIRT2266640	hsa-miR-4469	CLIP-seq
MIRT1128057	hsa-miR-4486	CLIP-seq
MIRT2266641	hsa-miR-4520a-3p	CLIP-seq
MIRT2266642	hsa-miR-4526	CLIP-seq
MIRT2266643	hsa-miR-4638-3p	CLIP-seq
MIRT2036401	hsa-miR-4639-3p	CLIP-seq
MIRT1128062	hsa-miR-4642	CLIP-seq
MIRT1128063	hsa-miR-4649-5p	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT740154	hsa-miR-4678	CLIP-seq
MIRT2266644	hsa-miR-4685-3p	CLIP-seq
MIRT2036405	hsa-miR-4703-5p	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT2266645	hsa-miR-4712-5p	CLIP-seq
MIRT2036406	hsa-miR-4713-5p	CLIP-seq
MIRT2036407	hsa-miR-4714-5p	CLIP-seq
MIRT1128068	hsa-miR-4717-3p	CLIP-seq
MIRT2266646	hsa-miR-4738-3p	CLIP-seq
MIRT2266647	hsa-miR-4742-5p	CLIP-seq
MIRT2266648	hsa-miR-4771	CLIP-seq
MIRT2266649	hsa-miR-4775	CLIP-seq
MIRT2266650	hsa-miR-4776-5p	CLIP-seq
MIRT2036408	hsa-miR-4784	CLIP-seq
MIRT1128075	hsa-miR-4789-5p	CLIP-seq
MIRT2266651	hsa-miR-487b	CLIP-seq
MIRT1128078	hsa-miR-505	CLIP-seq
MIRT2266652	hsa-miR-506	CLIP-seq
MIRT2266653	hsa-miR-5096	CLIP-seq
MIRT1128080	hsa-miR-513a-5p	CLIP-seq
MIRT2036410	hsa-miR-548h	CLIP-seq
MIRT2036411	hsa-miR-548j	CLIP-seq
MIRT2266654	hsa-miR-590-3p	CLIP-seq
MIRT1128088	hsa-miR-612	CLIP-seq
MIRT2266655	hsa-miR-617	CLIP-seq
MIRT2266656	hsa-miR-619	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT2266657	hsa-miR-631	CLIP-seq
MIRT2266658	hsa-miR-634	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT2036412	hsa-miR-668	CLIP-seq
MIRT1128091	hsa-miR-758	CLIP-seq
MIRT2266659	hsa-miR-767-5p	CLIP-seq
MIRT2266660	hsa-miR-770-5p	CLIP-seq
MIRT2036413	hsa-miR-887	CLIP-seq
MIRT2036414	hsa-miR-892a	CLIP-seq
MIRT1128092	hsa-miR-92a	CLIP-seq
MIRT1128093	hsa-miR-92b	CLIP-seq
MIRT2036387	hsa-miR-1227	CLIP-seq
MIRT2036392	hsa-miR-3120-3p	CLIP-seq
MIRT2036393	hsa-miR-3150b-3p	CLIP-seq
MIRT2390550	hsa-miR-3174	CLIP-seq
MIRT2390551	hsa-miR-339-5p	CLIP-seq
MIRT2390552	hsa-miR-3606	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT2390553	hsa-miR-3682-5p	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT2036395	hsa-miR-3942-5p	CLIP-seq
MIRT2036396	hsa-miR-4251	CLIP-seq
MIRT2266638	hsa-miR-4287	CLIP-seq
MIRT2036398	hsa-miR-4329	CLIP-seq
MIRT2390554	hsa-miR-4424	CLIP-seq
MIRT2266640	hsa-miR-4469	CLIP-seq
MIRT2036401	hsa-miR-4639-3p	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT2266644	hsa-miR-4685-3p	CLIP-seq
MIRT2036405	hsa-miR-4703-5p	CLIP-seq
MIRT2036406	hsa-miR-4713-5p	CLIP-seq
MIRT2036407	hsa-miR-4714-5p	CLIP-seq
MIRT2036408	hsa-miR-4784	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT2036412	hsa-miR-668	CLIP-seq
MIRT2390555	hsa-miR-921	CLIP-seq
MIRT740154	hsa-miR-4678	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128010	hsa-miR-1284	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT1128038	hsa-miR-3611	CLIP-seq
MIRT2438485	hsa-miR-4704-5p	CLIP-seq
MIRT1128075	hsa-miR-4789-5p	CLIP-seq
MIRT2266653	hsa-miR-5096	CLIP-seq
MIRT1128080	hsa-miR-513a-5p	CLIP-seq
MIRT1128091	hsa-miR-758	CLIP-seq
MIRT2453656	hsa-miR-1321	CLIP-seq
MIRT2453657	hsa-miR-148a	CLIP-seq
MIRT2453658	hsa-miR-148b	CLIP-seq
MIRT2453659	hsa-miR-152	CLIP-seq
MIRT2453660	hsa-miR-3136-3p	CLIP-seq
MIRT2453661	hsa-miR-4270	CLIP-seq
MIRT2453662	hsa-miR-4276	CLIP-seq
MIRT2453663	hsa-miR-4441	CLIP-seq
MIRT2453664	hsa-miR-4739	CLIP-seq
MIRT2453665	hsa-miR-4755-3p	CLIP-seq
MIRT2453666	hsa-miR-4756-5p	CLIP-seq
MIRT2453656	hsa-miR-1321	CLIP-seq
MIRT2453657	hsa-miR-148a	CLIP-seq
MIRT2453658	hsa-miR-148b	CLIP-seq
MIRT2453659	hsa-miR-152	CLIP-seq
MIRT2453660	hsa-miR-3136-3p	CLIP-seq
MIRT2453661	hsa-miR-4270	CLIP-seq
MIRT2453662	hsa-miR-4276	CLIP-seq
MIRT2453663	hsa-miR-4441	CLIP-seq
MIRT2453664	hsa-miR-4739	CLIP-seq
MIRT2453665	hsa-miR-4755-3p	CLIP-seq
MIRT2453666	hsa-miR-4756-5p	CLIP-seq
MIRT2566278	hsa-miR-1200	CLIP-seq
MIRT2036387	hsa-miR-1227	CLIP-seq
MIRT1128003	hsa-miR-1231	CLIP-seq
MIRT2266618	hsa-miR-124	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128010	hsa-miR-1284	CLIP-seq
MIRT2566279	hsa-miR-135a	CLIP-seq
MIRT2566280	hsa-miR-135b	CLIP-seq
MIRT1128014	hsa-miR-137	CLIP-seq
MIRT2266621	hsa-miR-141	CLIP-seq
MIRT2036389	hsa-miR-145	CLIP-seq
MIRT2266622	hsa-miR-200a	CLIP-seq
MIRT1556632	hsa-miR-22	CLIP-seq
MIRT2566281	hsa-miR-2277-3p	CLIP-seq
MIRT1128023	hsa-miR-2278	CLIP-seq
MIRT1128024	hsa-miR-25	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT2566282	hsa-miR-3117-3p	CLIP-seq
MIRT2036392	hsa-miR-3120-3p	CLIP-seq
MIRT2566283	hsa-miR-3133	CLIP-seq
MIRT2036393	hsa-miR-3150b-3p	CLIP-seq
MIRT2566284	hsa-miR-3166	CLIP-seq
MIRT2566285	hsa-miR-3169	CLIP-seq
MIRT1128033	hsa-miR-32	CLIP-seq
MIRT1128036	hsa-miR-3591-3p	CLIP-seq
MIRT2566286	hsa-miR-3605-5p	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT1128038	hsa-miR-3611	CLIP-seq
MIRT1128039	hsa-miR-3622a-3p	CLIP-seq
MIRT1128040	hsa-miR-3622b-3p	CLIP-seq
MIRT1128041	hsa-miR-363	CLIP-seq
MIRT1128044	hsa-miR-367	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT2566287	hsa-miR-3714	CLIP-seq
MIRT2566288	hsa-miR-376c	CLIP-seq
MIRT2566289	hsa-miR-3908	CLIP-seq
MIRT2566290	hsa-miR-3910	CLIP-seq
MIRT2566291	hsa-miR-3919	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT2566292	hsa-miR-3942-3p	CLIP-seq
MIRT2036395	hsa-miR-3942-5p	CLIP-seq
MIRT2036396	hsa-miR-4251	CLIP-seq
MIRT2566293	hsa-miR-4324	CLIP-seq
MIRT2036398	hsa-miR-4329	CLIP-seq
MIRT2566294	hsa-miR-4421	CLIP-seq
MIRT2566295	hsa-miR-4428	CLIP-seq
MIRT2566296	hsa-miR-4433	CLIP-seq
MIRT2566297	hsa-miR-4490	CLIP-seq
MIRT2566298	hsa-miR-4515	CLIP-seq
MIRT2036401	hsa-miR-4639-3p	CLIP-seq
MIRT1128062	hsa-miR-4642	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT740154	hsa-miR-4678	CLIP-seq
MIRT2036405	hsa-miR-4703-5p	CLIP-seq
MIRT2438485	hsa-miR-4704-5p	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT2566299	hsa-miR-4707-5p	CLIP-seq
MIRT2266645	hsa-miR-4712-5p	CLIP-seq
MIRT2036407	hsa-miR-4714-5p	CLIP-seq
MIRT1128068	hsa-miR-4717-3p	CLIP-seq
MIRT1128071	hsa-miR-4747-5p	CLIP-seq
MIRT2566300	hsa-miR-4759	CLIP-seq
MIRT2566301	hsa-miR-4773	CLIP-seq
MIRT2566302	hsa-miR-4778-5p	CLIP-seq
MIRT2036408	hsa-miR-4784	CLIP-seq
MIRT1128075	hsa-miR-4789-5p	CLIP-seq
MIRT2566303	hsa-miR-4802-5p	CLIP-seq
MIRT2266652	hsa-miR-506	CLIP-seq
MIRT2266653	hsa-miR-5096	CLIP-seq
MIRT1128080	hsa-miR-513a-5p	CLIP-seq
MIRT2566304	hsa-miR-526b	CLIP-seq
MIRT2566305	hsa-miR-544b	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT2566306	hsa-miR-627	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT2036412	hsa-miR-668	CLIP-seq
MIRT1128091	hsa-miR-758	CLIP-seq
MIRT2566307	hsa-miR-765	CLIP-seq
MIRT2266660	hsa-miR-770-5p	CLIP-seq
MIRT2036414	hsa-miR-892a	CLIP-seq
MIRT2566308	hsa-miR-922	CLIP-seq
MIRT2566309	hsa-miR-924	CLIP-seq
MIRT1128092	hsa-miR-92a	CLIP-seq
MIRT1128093	hsa-miR-92b	CLIP-seq
MIRT2036387	hsa-miR-1227	CLIP-seq
MIRT1128003	hsa-miR-1231	CLIP-seq
MIRT1128007	hsa-miR-1266	CLIP-seq
MIRT2684463	hsa-miR-1273e	CLIP-seq
MIRT1128009	hsa-miR-128	CLIP-seq
MIRT1128011	hsa-miR-1285	CLIP-seq
MIRT2566279	hsa-miR-135a	CLIP-seq
MIRT2566280	hsa-miR-135b	CLIP-seq
MIRT1128014	hsa-miR-137	CLIP-seq
MIRT2266621	hsa-miR-141	CLIP-seq
MIRT2036389	hsa-miR-145	CLIP-seq
MIRT2684464	hsa-miR-1825	CLIP-seq
MIRT1128020	hsa-miR-1972	CLIP-seq
MIRT2684465	hsa-miR-199a-5p	CLIP-seq
MIRT2684466	hsa-miR-199b-5p	CLIP-seq
MIRT2266622	hsa-miR-200a	CLIP-seq
MIRT2684467	hsa-miR-218	CLIP-seq
MIRT1556632	hsa-miR-22	CLIP-seq
MIRT2566281	hsa-miR-2277-3p	CLIP-seq
MIRT1128024	hsa-miR-25	CLIP-seq
MIRT1128025	hsa-miR-27a	CLIP-seq
MIRT1128026	hsa-miR-27b	CLIP-seq
MIRT2036392	hsa-miR-3120-3p	CLIP-seq
MIRT2036393	hsa-miR-3150b-3p	CLIP-seq
MIRT1128032	hsa-miR-3187-5p	CLIP-seq
MIRT1128033	hsa-miR-32	CLIP-seq
MIRT1128036	hsa-miR-3591-3p	CLIP-seq
MIRT2566286	hsa-miR-3605-5p	CLIP-seq
MIRT1128037	hsa-miR-3607-3p	CLIP-seq
MIRT1128039	hsa-miR-3622a-3p	CLIP-seq
MIRT1128040	hsa-miR-3622b-3p	CLIP-seq
MIRT1128041	hsa-miR-363	CLIP-seq
MIRT1128042	hsa-miR-3664-3p	CLIP-seq
MIRT1128044	hsa-miR-367	CLIP-seq
MIRT1128045	hsa-miR-3686	CLIP-seq
MIRT2566287	hsa-miR-3714	CLIP-seq
MIRT1128049	hsa-miR-378g	CLIP-seq
MIRT2566289	hsa-miR-3908	CLIP-seq
MIRT2566291	hsa-miR-3919	CLIP-seq
MIRT1128050	hsa-miR-3921	CLIP-seq
MIRT2036395	hsa-miR-3942-5p	CLIP-seq
MIRT2036396	hsa-miR-4251	CLIP-seq
MIRT2684468	hsa-miR-4302	CLIP-seq
MIRT2036398	hsa-miR-4329	CLIP-seq
MIRT2684469	hsa-miR-4422	CLIP-seq
MIRT2566296	hsa-miR-4433	CLIP-seq
MIRT1128057	hsa-miR-4486	CLIP-seq
MIRT1128060	hsa-miR-4518	CLIP-seq
MIRT2036400	hsa-miR-452	CLIP-seq
MIRT2036401	hsa-miR-4639-3p	CLIP-seq
MIRT1128062	hsa-miR-4642	CLIP-seq
MIRT1128063	hsa-miR-4649-5p	CLIP-seq
MIRT1128064	hsa-miR-4650-5p	CLIP-seq
MIRT1128065	hsa-miR-4653-5p	CLIP-seq
MIRT2036403	hsa-miR-4676-3p	CLIP-seq
MIRT740154	hsa-miR-4678	CLIP-seq
MIRT2036405	hsa-miR-4703-5p	CLIP-seq
MIRT740155	hsa-miR-4705	CLIP-seq
MIRT2566299	hsa-miR-4707-5p	CLIP-seq
MIRT2266645	hsa-miR-4712-5p	CLIP-seq
MIRT2036407	hsa-miR-4714-5p	CLIP-seq
MIRT1128068	hsa-miR-4717-3p	CLIP-seq
MIRT2036408	hsa-miR-4784	CLIP-seq
MIRT2566303	hsa-miR-4802-5p	CLIP-seq
MIRT2566304	hsa-miR-526b	CLIP-seq
MIRT1128088	hsa-miR-612	CLIP-seq
MIRT740153	hsa-miR-624	CLIP-seq
MIRT2566306	hsa-miR-627	CLIP-seq
MIRT2684470	hsa-miR-636	CLIP-seq
MIRT2684471	hsa-miR-648	CLIP-seq
MIRT1128090	hsa-miR-659	CLIP-seq
MIRT2036412	hsa-miR-668	CLIP-seq
MIRT2566307	hsa-miR-765	CLIP-seq
MIRT2266660	hsa-miR-770-5p	CLIP-seq
MIRT2036414	hsa-miR-892a	CLIP-seq
MIRT2566308	hsa-miR-922	CLIP-seq
MIRT1128092	hsa-miR-92a	CLIP-seq
MIRT1128093	hsa-miR-92b	CLIP-seq
MIRT2036416	hsa-miR-943	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
HSF2	Repression	11557063

Show/Hide all(32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IBA
GO:0000165	Process	MAPK cascade	IEA
GO:0000165	Process	MAPK cascade	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	7716521
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004708	Function	MAP kinase kinase activity	IBA
GO:0004708	Function	MAP kinase kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	9808624, 15299019, 16533805, 21900206, 32707033, 34439869, 35271311
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0007165	Process	Signal transduction	TAS	7716521
GO:0007254	Process	JNK cascade	TAS	7716521
GO:0008545	Function	JUN kinase kinase activity	TAS
GO:0009611	Process	Response to wounding	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0033554	Process	Cellular response to stress	IEA
GO:0034390	Process	Smooth muscle cell apoptotic process	IEA
GO:0036481	Process	Intrinsic apoptotic signaling pathway in response to hydrogen peroxide	IEA
GO:0038095	Process	Fc-epsilon receptor signaling pathway	TAS
GO:0060090	Function	Molecular adaptor activity	EXP	34439869
GO:0071260	Process	Cellular response to mechanical stimulus	IEP	19593445
GO:0090398	Process	Cellular senescence	TAS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:2000672	Process	Negative regulation of motor neuron apoptotic process	IEA

MIM	HGNC	e!Ensembl
601335	6844	ENSG00000065559

Protein

UniProt ID

P45985

Protein name

Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1)

Protein function

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7,

PDB

3ALN , 3ALO , 3VUT , 8YP5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	102 → 367	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

Sequence

MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Sequence length

399

Interactions

View interactions

	KEGG		Reactome
	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway TNF signaling pathway GnRH signaling pathway Relaxin signaling pathway Growth hormone synthesis, secretion and action Alcoholic liver disease Epithelial cell signaling in Helicobacter pylori infection Salmonella infection Yersinia infection Chagas disease Hepatitis B Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Epstein-Barr virus infection Chemical carcinogenesis - reactive oxygen species Lipid and atherosclerosis Fluid shear stress and atherosclerosis		Oxidative Stress Induced Senescence FCERI mediated MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Uptake and function of anthrax toxins

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Asthma	Asthma	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS
Neuroblastoma	neuroblastoma	N/A	N/A	ClinVar
Pelvic Organ Prolapse	Pelvic organ prolapse	N/A	N/A	GWAS
Urolithiasis	Urolithiasis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (52)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenoma	Associate	28423721
Alzheimer Disease	Associate	26080319
Arthritis Rheumatoid	Associate	13130464, 16802349, 25732927
Atrial Fibrillation	Associate	32510852
Brain Neoplasms	Inhibit	15592684
Breast Neoplasms	Associate	15592684, 22522925, 22722193, 28027327, 35589867, 36656864, 39264897
Breast Neoplasms Male	Associate	24194916
Calcinosis Cutis	Associate	15592684, 24466137
Carcinogenesis	Associate	21518142, 22335172
Carcinoma Endometrioid	Associate	21575258
Carcinoma Intraductal Noninfiltrating	Associate	26249178, 28338653
Carcinoma Non Small Cell Lung	Associate	26165383
Carcinoma Pancreatic Ductal	Associate	33341545
Colonic Diseases	Associate	28179590
Colorectal Neoplasms	Associate	28423721, 32686686
Drug Related Side Effects and Adverse Reactions	Associate	31251836
Embolism Fat	Associate	18388185
Fused Teeth	Associate	29975246
Glycogen Storage Disease Type II	Associate	23940728
Histiocytosis Langerhans Cell	Associate	36064398
Infections	Associate	23797008
Inflammation	Associate	21518142, 22335172
Inflammatory Breast Neoplasms	Associate	32075053
Leukemia	Associate	15494423
Leukemia Myeloid	Associate	9858570
Leukemia Myeloid Acute	Associate	21518142
Lewy Body Disease	Associate	32887355
Liver Diseases	Associate	26165383
Lung Diseases	Associate	26165383, 28777004
Lung Neoplasms	Associate	12714585, 26560124
Melanoma	Associate	24008424
Neoplasm Metastasis	Inhibit	15592684, 17276500
Neoplasm Metastasis	Associate	21575258, 28423721
Neoplasms	Associate	15578079, 22335172, 22522925, 23319048, 23607596, 24194916, 26894955, 28423721, 31341961, 34158539, 36656864, 36681091, 37460928, 39264897
Neoplasms	Inhibit	16627982, 21575258, 33341545
Neoplasms Cystic Mucinous and Serous	Associate	21575258
Osteoglophonic dwarfism	Stimulate	31251836
Osteosarcoma	Associate	24556602
Ovarian Diseases	Associate	17276500
Ovarian Neoplasms	Inhibit	16627982, 17276500
Ovarian Neoplasms	Associate	18337456, 21575258
Prostatic Intraepithelial Neoplasia	Associate	32740981
Prostatic Neoplasms	Inhibit	18337456
Prostatic Neoplasms	Associate	26444865
Prostatitis	Associate	8650201
Rhabdomyosarcoma	Associate	23797008
Ring Chromosome 20 Syndrome	Stimulate	31251836
Sarcoma	Associate	29801054
Squamous Cell Carcinoma of Head and Neck	Associate	28319306, 36916400
Stomach Neoplasms	Associate	10854223, 21097718, 23921907, 25198898
Thyroiditis	Associate	27353001
Uterine Cervical Neoplasms	Associate	19010820, 22335172

MAP2K4 (mitogen-activated protein kinase kinase 4)