Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	64151
Gene name	Non-SMC condensin I complex subunit G
Gene symbol	NCAPG
Synonyms (NCBI Gene)	CAPGCHCGNY-MEL-3YCG1
Chromosome	4
Chromosome location	4p15.31
Summary	This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for

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Show/Hide all (191)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000171	hsa-miR-21-5p	Luciferase reporter assayQuantitative proteomic approach	19253296
MIRT016370	hsa-miR-193b-3p	Microarray	20304954
MIRT020693	hsa-miR-155-5p	Proteomics	18668040
MIRT023728	hsa-miR-1-3p	Proteomics	18668040
MIRT025382	hsa-miR-34a-5p	Proteomics	21566225
MIRT031595	hsa-miR-16-5p	Proteomics	18668040
MIRT039450	hsa-miR-421	CLASH	23622248
MIRT054110	hsa-miR-575	Microarray	22995316
MIRT724679	hsa-miR-1250-3p	HITS-CLIP	19536157
MIRT724678	hsa-miR-153-5p	HITS-CLIP	19536157
MIRT724677	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT724676	hsa-miR-4536-5p	HITS-CLIP	19536157
MIRT724675	hsa-miR-5696	HITS-CLIP	19536157
MIRT724674	hsa-miR-579-3p	HITS-CLIP	19536157
MIRT724673	hsa-miR-664b-3p	HITS-CLIP	19536157
MIRT724672	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT727100	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT727098	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT727099	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT727097	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT724679	hsa-miR-1250-3p	HITS-CLIP	19536157
MIRT724678	hsa-miR-153-5p	HITS-CLIP	19536157
MIRT724677	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT724676	hsa-miR-4536-5p	HITS-CLIP	19536157
MIRT724675	hsa-miR-5696	HITS-CLIP	19536157
MIRT724674	hsa-miR-579-3p	HITS-CLIP	19536157
MIRT724673	hsa-miR-664b-3p	HITS-CLIP	19536157
MIRT724672	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT1175834	hsa-miR-105	CLIP-seq
MIRT1175835	hsa-miR-1299	CLIP-seq
MIRT1175836	hsa-miR-300	CLIP-seq
MIRT1175837	hsa-miR-369-3p	CLIP-seq
MIRT1175838	hsa-miR-374a	CLIP-seq
MIRT1175839	hsa-miR-374b	CLIP-seq
MIRT1175840	hsa-miR-374c	CLIP-seq
MIRT1175841	hsa-miR-378	CLIP-seq
MIRT1175842	hsa-miR-378b	CLIP-seq
MIRT1175843	hsa-miR-378c	CLIP-seq
MIRT1175844	hsa-miR-378d	CLIP-seq
MIRT1175845	hsa-miR-378e	CLIP-seq
MIRT1175846	hsa-miR-378f	CLIP-seq
MIRT1175847	hsa-miR-378h	CLIP-seq
MIRT1175848	hsa-miR-378i	CLIP-seq
MIRT1175849	hsa-miR-381	CLIP-seq
MIRT1175850	hsa-miR-422a	CLIP-seq
MIRT1175851	hsa-miR-4476	CLIP-seq
MIRT1175852	hsa-miR-4633-5p	CLIP-seq
MIRT1175853	hsa-miR-4638-3p	CLIP-seq
MIRT1175854	hsa-miR-4661-5p	CLIP-seq
MIRT1175855	hsa-miR-4666-3p	CLIP-seq
MIRT1175856	hsa-miR-4729	CLIP-seq
MIRT1175857	hsa-miR-4781-3p	CLIP-seq
MIRT1175858	hsa-miR-4782-5p	CLIP-seq
MIRT1175859	hsa-miR-514	CLIP-seq
MIRT1175860	hsa-miR-514b-3p	CLIP-seq
MIRT1175861	hsa-miR-516b	CLIP-seq
MIRT1175862	hsa-miR-550b	CLIP-seq
MIRT1175863	hsa-miR-646	CLIP-seq
MIRT1175864	hsa-miR-651	CLIP-seq
MIRT1175865	hsa-miR-655	CLIP-seq
MIRT2050949	hsa-miR-181a	CLIP-seq
MIRT2050950	hsa-miR-181b	CLIP-seq
MIRT2050951	hsa-miR-181c	CLIP-seq
MIRT2050952	hsa-miR-181d	CLIP-seq
MIRT2050953	hsa-miR-4261	CLIP-seq
MIRT2050954	hsa-miR-4262	CLIP-seq
MIRT2050955	hsa-miR-4719	CLIP-seq
MIRT2050956	hsa-miR-494	CLIP-seq
MIRT2050957	hsa-miR-513b	CLIP-seq
MIRT2050958	hsa-miR-543	CLIP-seq
MIRT2280010	hsa-miR-1276	CLIP-seq
MIRT2280011	hsa-miR-142-5p	CLIP-seq
MIRT2050949	hsa-miR-181a	CLIP-seq
MIRT2050950	hsa-miR-181b	CLIP-seq
MIRT2050951	hsa-miR-181c	CLIP-seq
MIRT2050952	hsa-miR-181d	CLIP-seq
MIRT2280012	hsa-miR-23a	CLIP-seq
MIRT2280013	hsa-miR-23b	CLIP-seq
MIRT2280014	hsa-miR-23c	CLIP-seq
MIRT1175836	hsa-miR-300	CLIP-seq
MIRT2280015	hsa-miR-3065-5p	CLIP-seq
MIRT2280016	hsa-miR-340	CLIP-seq
MIRT2280017	hsa-miR-3654	CLIP-seq
MIRT2280018	hsa-miR-3662	CLIP-seq
MIRT2280019	hsa-miR-375	CLIP-seq
MIRT1175849	hsa-miR-381	CLIP-seq
MIRT2280020	hsa-miR-3913-3p	CLIP-seq
MIRT2280021	hsa-miR-3920	CLIP-seq
MIRT2280022	hsa-miR-410	CLIP-seq
MIRT2050953	hsa-miR-4261	CLIP-seq
MIRT2050954	hsa-miR-4262	CLIP-seq
MIRT2280023	hsa-miR-4273	CLIP-seq
MIRT2280024	hsa-miR-4311	CLIP-seq
MIRT2280025	hsa-miR-4421	CLIP-seq
MIRT2280026	hsa-miR-4464	CLIP-seq
MIRT2280027	hsa-miR-4496	CLIP-seq
MIRT1175853	hsa-miR-4638-3p	CLIP-seq
MIRT1175855	hsa-miR-4666-3p	CLIP-seq
MIRT2280028	hsa-miR-4677-5p	CLIP-seq
MIRT2050955	hsa-miR-4719	CLIP-seq
MIRT2280029	hsa-miR-4748	CLIP-seq
MIRT2280030	hsa-miR-4762-3p	CLIP-seq
MIRT2050956	hsa-miR-494	CLIP-seq
MIRT2280031	hsa-miR-495	CLIP-seq
MIRT2050957	hsa-miR-513b	CLIP-seq
MIRT1175859	hsa-miR-514	CLIP-seq
MIRT1175860	hsa-miR-514b-3p	CLIP-seq
MIRT2050958	hsa-miR-543	CLIP-seq
MIRT2280032	hsa-miR-548c-3p	CLIP-seq
MIRT2280033	hsa-miR-583	CLIP-seq
MIRT2280034	hsa-miR-665	CLIP-seq
MIRT2454920	hsa-miR-1260	CLIP-seq
MIRT2454921	hsa-miR-1260b	CLIP-seq
MIRT1175835	hsa-miR-1299	CLIP-seq
MIRT2050949	hsa-miR-181a	CLIP-seq
MIRT2050950	hsa-miR-181b	CLIP-seq
MIRT2050951	hsa-miR-181c	CLIP-seq
MIRT2050952	hsa-miR-181d	CLIP-seq
MIRT2454922	hsa-miR-1827	CLIP-seq
MIRT2454923	hsa-miR-188-3p	CLIP-seq
MIRT2454924	hsa-miR-1972	CLIP-seq
MIRT2280012	hsa-miR-23a	CLIP-seq
MIRT2280013	hsa-miR-23b	CLIP-seq
MIRT2280014	hsa-miR-23c	CLIP-seq
MIRT1175836	hsa-miR-300	CLIP-seq
MIRT2454925	hsa-miR-3156-3p	CLIP-seq
MIRT2454926	hsa-miR-3168	CLIP-seq
MIRT2454927	hsa-miR-3190	CLIP-seq
MIRT1175837	hsa-miR-369-3p	CLIP-seq
MIRT1175838	hsa-miR-374a	CLIP-seq
MIRT1175839	hsa-miR-374b	CLIP-seq
MIRT1175840	hsa-miR-374c	CLIP-seq
MIRT1175841	hsa-miR-378	CLIP-seq
MIRT1175842	hsa-miR-378b	CLIP-seq
MIRT1175843	hsa-miR-378c	CLIP-seq
MIRT1175844	hsa-miR-378d	CLIP-seq
MIRT1175845	hsa-miR-378e	CLIP-seq
MIRT1175846	hsa-miR-378f	CLIP-seq
MIRT1175847	hsa-miR-378h	CLIP-seq
MIRT1175848	hsa-miR-378i	CLIP-seq
MIRT1175849	hsa-miR-381	CLIP-seq
MIRT2454928	hsa-miR-3908	CLIP-seq
MIRT2454929	hsa-miR-3924	CLIP-seq
MIRT2454930	hsa-miR-3926	CLIP-seq
MIRT2454931	hsa-miR-3938	CLIP-seq
MIRT2454932	hsa-miR-3942-5p	CLIP-seq
MIRT2454933	hsa-miR-3973	CLIP-seq
MIRT1175850	hsa-miR-422a	CLIP-seq
MIRT2050953	hsa-miR-4261	CLIP-seq
MIRT2050954	hsa-miR-4262	CLIP-seq
MIRT2454934	hsa-miR-4301	CLIP-seq
MIRT2454935	hsa-miR-4438	CLIP-seq
MIRT1175851	hsa-miR-4476	CLIP-seq
MIRT2280027	hsa-miR-4496	CLIP-seq
MIRT2454936	hsa-miR-4528	CLIP-seq
MIRT1175852	hsa-miR-4633-5p	CLIP-seq
MIRT1175853	hsa-miR-4638-3p	CLIP-seq
MIRT1175855	hsa-miR-4666-3p	CLIP-seq
MIRT2454937	hsa-miR-4703-5p	CLIP-seq
MIRT2050955	hsa-miR-4719	CLIP-seq
MIRT2454938	hsa-miR-4766-3p	CLIP-seq
MIRT1175858	hsa-miR-4782-5p	CLIP-seq
MIRT2454939	hsa-miR-4795-3p	CLIP-seq
MIRT2050956	hsa-miR-494	CLIP-seq
MIRT2454940	hsa-miR-5095	CLIP-seq
MIRT2050957	hsa-miR-513b	CLIP-seq
MIRT1175861	hsa-miR-516b	CLIP-seq
MIRT2050958	hsa-miR-543	CLIP-seq
MIRT2454941	hsa-miR-548a-5p	CLIP-seq
MIRT2454942	hsa-miR-548ab	CLIP-seq
MIRT2454943	hsa-miR-548ak	CLIP-seq
MIRT2454944	hsa-miR-548b-5p	CLIP-seq
MIRT2454945	hsa-miR-548c-5p	CLIP-seq
MIRT2454946	hsa-miR-548d-5p	CLIP-seq
MIRT2454947	hsa-miR-548h	CLIP-seq
MIRT2454948	hsa-miR-548i	CLIP-seq
MIRT2454949	hsa-miR-548j	CLIP-seq
MIRT2454950	hsa-miR-548w	CLIP-seq
MIRT2454951	hsa-miR-548y	CLIP-seq
MIRT2454952	hsa-miR-559	CLIP-seq
MIRT1175864	hsa-miR-651	CLIP-seq
MIRT1175865	hsa-miR-655	CLIP-seq
MIRT2454953	hsa-miR-656	CLIP-seq
MIRT2280034	hsa-miR-665	CLIP-seq
MIRT2454954	hsa-miR-671-5p	CLIP-seq
MIRT2454955	hsa-miR-922	CLIP-seq
MIRT2454956	hsa-miR-944	CLIP-seq
MIRT2280010	hsa-miR-1276	CLIP-seq
MIRT2578549	hsa-miR-1306	CLIP-seq
MIRT2280024	hsa-miR-4311	CLIP-seq
MIRT2280033	hsa-miR-583	CLIP-seq

Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000779	Component	Condensed chromosome, centromeric region	IEA
GO:0000793	Component	Condensed chromosome	IBA
GO:0000793	Component	Condensed chromosome	IEA
GO:0000794	Component	Condensed nuclear chromosome	IEA
GO:0000794	Component	Condensed nuclear chromosome	ISO
GO:0000796	Component	Condensin complex	IDA	11136719
GO:0000796	Component	Condensin complex	IEA
GO:0000796	Component	Condensin complex	NAS	17268547
GO:0005515	Function	Protein binding	IPI	12138188, 17268547, 24981860, 26496610, 28514442, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	10910072
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007076	Process	Mitotic chromosome condensation	IBA
GO:0007076	Process	Mitotic chromosome condensation	IDA	11136719
GO:0007076	Process	Mitotic chromosome condensation	IEA
GO:0007076	Process	Mitotic chromosome condensation	NAS	10910072
GO:0016020	Component	Membrane	HDA	19946888
GO:0030261	Process	Chromosome condensation	IEA
GO:0051301	Process	Cell division	IEA
GO:0051984	Process	Positive regulation of chromosome segregation	IEA
GO:0051984	Process	Positive regulation of chromosome segregation	ISO
GO:1905820	Process	Positive regulation of chromosome separation	IEA
GO:1905820	Process	Positive regulation of chromosome separation	ISO
GO:1905821	Process	Positive regulation of chromosome condensation	IDA	17268547

MIM	HGNC	e!Ensembl
606280	24304	ENSG00000109805

Q9BPX3

Protein name

Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog)

Protein function

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type

PDB

6IGX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12719	Cnd3	559 → 859	Nuclear condensing complex subunits, C-term domain	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in testis. {ECO:0000269|PubMed:10910072}.

Sequence

MGAERRLLSIKEAFRLAQQPHQNQAKLVVALSRTYRTMDDKTVFHEEFIHYLKYVMVVYK
REPAVERVIEFAAKFVTSFHQSDMEDDEEEEDGGLLNYLFTFLLKSHEANSNAVRFRVCL
LINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPKDDECPVV
NAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRA
MSIAQRVMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSEVAVSV
LNALFSITPLSELVGLCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQI
LPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGR
KKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIRAPIVTVGVNN
DPADVRKKELKMAEIKVKLIEAKEALENCITLQDFNRASELKEEIKALEDARINLLKETE
QLEIKEVHIEKNDAETLQKCLILCYELLKQMSISTGLSATMNGIIESLILPGIISIHPVV
RNLAVLCLGCCGLQNQDFARKHFVLLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTK
KIKTLHCEGTEINSDDEQESKEVEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMF
SGLLVSSRILSRLILLWYNPVTEEDVQLRHCLGVFFPVFAYASRTNQECFEEAFLPTLQT
LANAPASSPLAEIDITNVAELLVDLTRPSGLNPQAKTSQDYQALTVHDNLAMKICNEILT
SPCSPEIRVYTKALSSLELSSHLAKDLLVLLNEILEQVKDRTCLRALEKIKIQLEKGNKE
FGDQAEAAQDATLTTTTFQNEDEKNKEVYMTPLRGVKATQASKSTQLKTNRGQRKVTVSA
RTNRRCQTAEADSESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS

Sequence length

1015

Interactions

View interactions

	Reactome
			Condensation of Prometaphase Chromosomes

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Clear cell carcinoma of kidney	Uncertain significance	rs148449510	RCV005930865

Show/Hide Text Mining Associations (39)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	35810236
Adenocarcinoma of Lung	Stimulate	37553792
Azoospermia	Associate	35219767
Breast Neoplasms	Associate	34675265
Carcinogenesis	Associate	36442414, 37553792
Carcinoma Adenoid Cystic	Associate	37861550
Carcinoma Hepatocellular	Stimulate	28737823
Carcinoma Hepatocellular	Associate	29843214, 30702595, 31746405, 34315286, 34919223, 35322101, 36317111, 37861550
Carcinoma Pancreatic Ductal	Associate	35963640
Carcinoma Renal Cell	Associate	29968393, 32626756
Carcinoma Renal Cell	Stimulate	35601741
Carcinoma Squamous Cell	Associate	33477943
Carcinosarcoma	Associate	36186000
Colonic Neoplasms	Associate	35392038
Colorectal Neoplasms	Associate	35774271, 36442414
Endometrial Neoplasms	Associate	36186000
Esophageal Squamous Cell Carcinoma	Associate	33345608
Glioma	Associate	36703644
Inflammation	Associate	37861550
Liver Cirrhosis	Associate	37861550
Lymphoma Non Hodgkin	Associate	26933822
Melanoma	Associate	17611626
Metabolic Syndrome	Associate	37049604
Necrosis	Associate	37861550
Neoplasm Invasiveness	Associate	34919223
Neoplasm Metastasis	Stimulate	28737823
Neoplasm Metastasis	Associate	37335105
Neoplasms	Associate	24074379, 28737823, 29608247, 34315286, 34919223, 35601741, 35963640, 35986371, 37861550
Neuroblastoma	Associate	37834394
Ovarian Diseases	Associate	36186000
Ovarian Neoplasms	Associate	34577856
Ovarian Neoplasms	Stimulate	35986371
Pancreatic Neoplasms	Associate	35601741
Prostatic Neoplasms	Associate	36245843, 36834602
Prostatic Neoplasms Castration Resistant	Associate	29608247
Sarcoma Ewing	Associate	35126643
Stomach Neoplasms	Associate	30390708, 37335105
Thymoma	Associate	30787364
Urinary Bladder Neoplasms	Associate	35685866

NCAPG (non-SMC condensin I complex subunit G)