KIF9 (kinesin family member 9)

Gene

• Entrez ID: 64147
• Gene name: Kinesin family member 9
• Gene symbol: KIF9
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3p21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT738649	hsa-miR-197	CLIP-seq
MIRT738650	hsa-miR-3670	CLIP-seq
MIRT738651	hsa-miR-4268	CLIP-seq
MIRT738658	hsa-miR-1182	CLIP-seq
MIRT738660	hsa-miR-146a	CLIP-seq
MIRT738659	hsa-miR-146b-5p	CLIP-seq
MIRT738656	hsa-miR-3126-5p	CLIP-seq
MIRT738653	hsa-miR-4300	CLIP-seq
MIRT738654	hsa-miR-4419a	CLIP-seq
MIRT738655	hsa-miR-4510	CLIP-seq
MIRT738657	hsa-miR-4649-3p	CLIP-seq
MIRT738652	hsa-miR-920	CLIP-seq
MIRT738658	hsa-miR-1182	CLIP-seq
MIRT738660	hsa-miR-146a	CLIP-seq
MIRT738659	hsa-miR-146b-5p	CLIP-seq
MIRT738649	hsa-miR-197	CLIP-seq
MIRT738656	hsa-miR-3126-5p	CLIP-seq
MIRT738650	hsa-miR-3670	CLIP-seq
MIRT738651	hsa-miR-4268	CLIP-seq
MIRT738653	hsa-miR-4300	CLIP-seq
MIRT738654	hsa-miR-4419a	CLIP-seq
MIRT738655	hsa-miR-4510	CLIP-seq
MIRT738657	hsa-miR-4649-3p	CLIP-seq
MIRT738652	hsa-miR-920	CLIP-seq
MIRT2025500	hsa-miR-4459	CLIP-seq
MIRT2025501	hsa-miR-4722-3p	CLIP-seq
MIRT2025502	hsa-miR-4755-3p	CLIP-seq
MIRT2025503	hsa-miR-4763-5p	CLIP-seq
MIRT2025504	hsa-miR-665	CLIP-seq
MIRT2025505	hsa-miR-765	CLIP-seq
MIRT738658	hsa-miR-1182	CLIP-seq
MIRT738660	hsa-miR-146a	CLIP-seq
MIRT738659	hsa-miR-146b-5p	CLIP-seq
MIRT738656	hsa-miR-3126-5p	CLIP-seq
MIRT738661	hsa-miR-3925-5p	CLIP-seq
MIRT738653	hsa-miR-4300	CLIP-seq
MIRT738654	hsa-miR-4419a	CLIP-seq
MIRT738655	hsa-miR-4510	CLIP-seq
MIRT738657	hsa-miR-4649-3p	CLIP-seq
MIRT738652	hsa-miR-920	CLIP-seq
MIRT738649	hsa-miR-197	CLIP-seq
MIRT738650	hsa-miR-3670	CLIP-seq
MIRT738651	hsa-miR-4268	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002102	Component	Podosome	IDA	21119006
GO:0003777	Function	Microtubule motor activity	IBA
GO:0003777	Function	Microtubule motor activity	IEA
GO:0005515	Function	Protein binding	IPI	21119006, 23455924, 26871637, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005871	Component	Kinesin complex	IBA
GO:0005874	Component	Microtubule	IBA
GO:0005874	Component	Microtubule	IDA	21119006
GO:0005874	Component	Microtubule	IEA
GO:0005929	Component	Cilium	IEA
GO:0007018	Process	Microtubule-based movement	IBA
GO:0007018	Process	Microtubule-based movement	IEA
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0016887	Function	ATP hydrolysis activity	IBA
GO:0022617	Process	Extracellular matrix disassembly	IMP	21119006
GO:0031514	Component	Motile cilium	IEA
GO:0031982	Component	Vesicle	IDA	21119006
GO:0036126	Component	Sperm flagellum	IEA
GO:0036126	Component	Sperm flagellum	ISS
GO:0042802	Function	Identical protein binding	IPI	21119006
GO:0042995	Component	Cell projection	IEA
GO:0071801	Process	Regulation of podosome assembly	IMP	21119006
GO:1901317	Process	Regulation of flagellated sperm motility	IEA
GO:1901317	Process	Regulation of flagellated sperm motility	ISS
GO:1903008	Process	Organelle disassembly	IMP	21119006

Other IDs

• MIM: 607910
• HGNC: 16666
• e!Ensembl: ENSG00000088727

Protein

• UniProt ID: Q9HAQ2
• Protein name: Kinesin-like protein KIF9
• Protein function: Essential for normal male fertility and for progressive motility of spermatozoa.
• PDB: 3NWN
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00225	Kinesin	12 → 340	Kinesin motor domain	Domain

• Sequence:

  MGTRKKVHAFVRVKPTDDFAHEMIRYGDDKRSIDIHLKKDIRRGVVNNQQTDWSFKLDGV
  LHDASQDLVYETVAKDVVSQALDGYNGTIMCYGQTGAGKTYTMMGATENYKHRGILPRAL
  QQVFRMIEERPTHAITVRVSYLEIYNESLFDLLSTLPYVGPSVTPMTIVENPQGVFIKGL
  SVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYLEAHSRTLSEEKYITSK
  INLVDLAGSERLGKSGSEGQVLKEATYINKSLSFLEQAIIALGDQKRDHIPFRQCKLTHA
  LKDSLGGNCNMVLVTNIYGEAAQLEETLSSLRFASRMKLVTTEPAINEKYDAERMVKNLE
  KELALLKQELAIHDSLTNRTFVTYDPMDEIQIAEINSQVRRYLEGTLDEIDIISLRQIKE
  VFNQFRVVLSQQEQEVESTLRRKYTLIDRNDFAAISAIQKAGLVDVDGHLVGEPEGQNFG
  LGVAPFSTKPGKKAKSKKTFKEPLSSLARKEGASSPVNGKDLDYVSTSKTQLVPSSKDGD
  VKDMLSRDRETSSIEPLPSDSPKEELRPIRPDTPPSKPVAFEEFKNEQGSEINRIFKENK
  SILNERRKRASETTQHINAIKREIDVTKEALNFQKSLREKQGKYENKGLMIIDEEEFLLI
  LKLKDLKKQYRSEYQDLRDLRAEIQYCQHLVDQCRHRLLMEFDIWYNESFVIPEDMQMAL
  KPGGSIRPGMVPVNRIVSLGEDDQDKFSQLQQRVLPEGPDSISFYNAKVKIEQKHNYLKT
  MMGLQQAHRK

• Sequence length: 790

Pathways

KEGG:

Motor proteins

Reactome:

COPI-dependent Golgi-to-ER retrograde traffic
Kinesins