GAL3ST2 (galactose-3-O-sulfotransferase 2)

Gene
Gene SNPs Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64090
Gene name Gene Name - the full gene name approved by the HGNC.
Galactose-3-O-sulfotransferase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GAL3ST2
Synonyms (NCBI Gene) Gene synonyms aliases
GAL3ST-2, GP3ST
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q37.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 a
SNPs SNP information provided by dbSNP.
Gene SNPs Gene ontology Other IDs Protein Associated diseases
Show/Hide all(1)
SNP ID Visualize variation Clinical significance Consequence
rs372108744 C>T Likely-pathogenic Coding sequence variant, missense variant
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Gene ontology Other IDs Protein Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0001733 Function Galactosylceramide sulfotransferase activity IEA
GO:0005515 Function Protein binding IPI 25416956
GO:0008146 Function Sulfotransferase activity IBA 21873635
GO:0008146 Function Sulfotransferase activity IDA 11029462
GO:0008150 Process Biological_process ND
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
608237 24869 ENSG00000154252
Protein
Gene SNPs Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9H3Q3
Protein name Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2) (Glycoprotein beta-Gal 3'-sulfotransferase 2)
Protein function Transfers a sulfate group to the hydroxyl group at C3 of non-reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3-GlcNAc) and type 2 (Gal-beta-1,4-GlcNAc) chains with similar efficiency.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06990 Gal-3-0_sulfotr 1 → 384 Galactose-3-O-sulfotransferase Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. Detected in heart, stomach, colon, liver and spleen, in epithelial cells lining the lower to middle layer of the crypts in colonic mucosa, hepatocytes surrounding the central vein of the liver, extravillous cytotrophoblasts
Sequence
Sequence length 398
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene SNPs Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 26974007
Show/Hide Unknown Diseases (3)
Unknown
Disease term Disease name Evidence References Source
Crohn disease Crohn Disease 26192919, 26974007 ClinVar
Asthma Asthma GWAS
Crohn Disease Crohn Disease GWAS
Show/Hide Text Mining Associations (2)
Associations from Text Mining
Disease Name Relationship Type References
Neoplasms Associate 27322736, 31676359
Prostatic Neoplasms Associate 27322736