CLSPN (claspin)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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63967 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Claspin |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CLSPN |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p34.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a norm |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||
| UniProt ID | Q9HAW4 | |
| Protein name | Claspin (hClaspin) | |
| Protein function | Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation (PubMed:12766152, PubMed:15190204, PubMed:15707391, PubMed:16123041). Adapter protein wh | |
| PDB | 7AKO , 7PFO , 7PLO , 8B9D | |
| Family and domains | ||
| Sequence |
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| Sequence length | 1339 | |
| Interactions | View interactions | |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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