Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	639
Gene name Gene Name - the full gene name approved by the HGNC.	PR/SET domain 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PRDM1
Synonyms (NCBI Gene) Gene synonyms aliases	BLIMP-1, BLIMP1, PRDI-BF1
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q21
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induc

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001936	hsa-let-7a-5p	Luciferase reporter assay	18583325
MIRT004279	hsa-miR-127-3p	qRT-PCR, Luciferase reporter assay, Western blot	19530237
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT001936	hsa-let-7a-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	19956200
MIRT001936	hsa-let-7a-5p	Luciferase reporter assay	18583325
MIRT001937	hsa-miR-9-5p	Luciferase reporter assay	18583325
MIRT004533	hsa-miR-125b-5p	qRT-PCR, Luciferase reporter assay	20497960
MIRT001936	hsa-let-7a-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT001936	hsa-let-7a-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT005513	hsa-let-7b-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT005513	hsa-let-7b-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT005514	hsa-let-7f-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT005514	hsa-let-7f-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	20651244
MIRT001937	hsa-miR-9-5p	ChIP-seq, FACS, Luciferase reporter assay, qRT-PCR	23129528
MIRT001937	hsa-miR-9-5p	ChIP-seq, FACS, Luciferase reporter assay, qRT-PCR	23129528
MIRT001937	hsa-miR-9-5p	ChIP-seq, FACS, Luciferase reporter assay, qRT-PCR	23129528
MIRT007218	hsa-miR-30a-5p	Luciferase reporter assay	23348703
MIRT037062	hsa-miR-877-3p	CLASH	23622248
MIRT054801	hsa-miR-223-3p	Luciferase reporter assay, qRT-PCR, Western blot	24438193
MIRT054801	hsa-miR-223-3p	Luciferase reporter assay, qRT-PCR, Western blot	24438193
MIRT054801	hsa-miR-223-3p	Luciferase reporter assay, qRT-PCR, Western blot	24438193
MIRT437582	hsa-miR-125a-5p	Microarray, qRT-PCR	22815788
MIRT437596	hsa-miR-140-5p	Microarray, qRT-PCR	22815788
MIRT054801	hsa-miR-223-3p	Microarray, qRT-PCR	22815788
MIRT005514	hsa-let-7f-5p	qRT-PCR	24405266
MIRT005514	hsa-let-7f-5p	qRT-PCR	24405266
MIRT005514	hsa-let-7f-5p	qRT-PCR	24405266
MIRT005514	hsa-let-7f-5p	qRT-PCR	24405266
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT217179	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT007218	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT167510	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT167508	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT167509	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT167511	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT217179	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT731781	hsa-miR-222-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731781	hsa-miR-222-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731781	hsa-miR-222-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731781	hsa-miR-222-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731781	hsa-miR-222-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT004533	hsa-miR-125b-5p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731782	hsa-miR-101-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731782	hsa-miR-101-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731782	hsa-miR-101-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT731782	hsa-miR-101-3p	Chromatin immunoprecipitation, Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	26655851
MIRT004533	hsa-miR-125b-5p	Luciferase reporter assay, qRT-PCR, Western blot	27613090
MIRT217176	hsa-miR-125a-3p	Chromatin immunoprecipitation, Microarray, qRT-PCR, Western blot	28052011
MIRT007218	hsa-miR-30a-5p	qRT-PCR	26472042
MIRT217240	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	27418678
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	27418678
MIRT610586	hsa-miR-874-3p	HITS-CLIP	27418678
MIRT610589	hsa-miR-938	HITS-CLIP	27418678
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610589	hsa-miR-938	HITS-CLIP	23824327
MIRT610588	hsa-miR-6886-3p	HITS-CLIP	23824327
MIRT610587	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT610586	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT217240	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1259944	hsa-let-7a	CLIP-seq
MIRT1259945	hsa-let-7b	CLIP-seq
MIRT1259946	hsa-let-7c	CLIP-seq
MIRT1259947	hsa-let-7d	CLIP-seq
MIRT1259948	hsa-let-7e	CLIP-seq
MIRT1259949	hsa-let-7f	CLIP-seq
MIRT1259950	hsa-let-7g	CLIP-seq
MIRT1259951	hsa-let-7i	CLIP-seq
MIRT1259952	hsa-miR-106a	CLIP-seq
MIRT1259953	hsa-miR-106b	CLIP-seq
MIRT1259954	hsa-miR-1193	CLIP-seq
MIRT1259955	hsa-miR-142-5p	CLIP-seq
MIRT1259956	hsa-miR-17	CLIP-seq
MIRT1259957	hsa-miR-202	CLIP-seq
MIRT1259958	hsa-miR-20a	CLIP-seq
MIRT1259959	hsa-miR-20b	CLIP-seq
MIRT1259960	hsa-miR-2116	CLIP-seq
MIRT1259961	hsa-miR-2392	CLIP-seq
MIRT1259962	hsa-miR-2467-3p	CLIP-seq
MIRT1259963	hsa-miR-3134	CLIP-seq
MIRT1259964	hsa-miR-3153	CLIP-seq
MIRT1259965	hsa-miR-3609	CLIP-seq
MIRT1259966	hsa-miR-3613-3p	CLIP-seq
MIRT1259967	hsa-miR-365	CLIP-seq
MIRT1259968	hsa-miR-3654	CLIP-seq
MIRT1259969	hsa-miR-3678-3p	CLIP-seq
MIRT1259970	hsa-miR-3688-5p	CLIP-seq
MIRT1259971	hsa-miR-3924	CLIP-seq
MIRT1259972	hsa-miR-4311	CLIP-seq
MIRT1259973	hsa-miR-4428	CLIP-seq
MIRT1259974	hsa-miR-4458	CLIP-seq
MIRT1259975	hsa-miR-4470	CLIP-seq
MIRT1259976	hsa-miR-4487	CLIP-seq
MIRT1259977	hsa-miR-4500	CLIP-seq
MIRT1259978	hsa-miR-450b-5p	CLIP-seq
MIRT1259979	hsa-miR-4638-3p	CLIP-seq
MIRT1259980	hsa-miR-4668-5p	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT1259982	hsa-miR-4710	CLIP-seq
MIRT1259983	hsa-miR-4719	CLIP-seq
MIRT1259984	hsa-miR-4792	CLIP-seq
MIRT1259985	hsa-miR-4796-3p	CLIP-seq
MIRT1259986	hsa-miR-519d	CLIP-seq
MIRT1259987	hsa-miR-548ah	CLIP-seq
MIRT1259988	hsa-miR-603	CLIP-seq
MIRT1259989	hsa-miR-653	CLIP-seq
MIRT1259990	hsa-miR-874	CLIP-seq
MIRT1259991	hsa-miR-93	CLIP-seq
MIRT1259992	hsa-miR-98	CLIP-seq
MIRT1259960	hsa-miR-2116	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT1259993	hsa-miR-548n	CLIP-seq
MIRT1259990	hsa-miR-874	CLIP-seq
MIRT1259990	hsa-miR-874	CLIP-seq
MIRT1259960	hsa-miR-2116	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT1259990	hsa-miR-874	CLIP-seq
MIRT2076573	hsa-miR-223	CLIP-seq
MIRT2076574	hsa-miR-4328	CLIP-seq
MIRT2076575	hsa-miR-4762-3p	CLIP-seq
MIRT2076576	hsa-miR-767-5p	CLIP-seq
MIRT1259983	hsa-miR-4719	CLIP-seq
MIRT1259990	hsa-miR-874	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT2457097	hsa-miR-2117	CLIP-seq
MIRT2457098	hsa-miR-375	CLIP-seq
MIRT2457099	hsa-miR-4273	CLIP-seq
MIRT2457100	hsa-miR-4292	CLIP-seq
MIRT2457101	hsa-miR-4308	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT2465901	hsa-miR-1236	CLIP-seq
MIRT2457097	hsa-miR-2117	CLIP-seq
MIRT2457098	hsa-miR-375	CLIP-seq
MIRT2457099	hsa-miR-4273	CLIP-seq
MIRT2457100	hsa-miR-4292	CLIP-seq
MIRT2457101	hsa-miR-4308	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT2465902	hsa-miR-4753-3p	CLIP-seq
MIRT2465901	hsa-miR-1236	CLIP-seq
MIRT2599876	hsa-miR-1243	CLIP-seq
MIRT2599877	hsa-miR-1275	CLIP-seq
MIRT2599878	hsa-miR-1287	CLIP-seq
MIRT2457097	hsa-miR-2117	CLIP-seq
MIRT2076573	hsa-miR-223	CLIP-seq
MIRT2599879	hsa-miR-300	CLIP-seq
MIRT2599880	hsa-miR-3065-5p	CLIP-seq
MIRT2599881	hsa-miR-3074-5p	CLIP-seq
MIRT2599882	hsa-miR-30a	CLIP-seq
MIRT2599883	hsa-miR-30b	CLIP-seq
MIRT2599884	hsa-miR-30c	CLIP-seq
MIRT2599885	hsa-miR-30d	CLIP-seq
MIRT2599886	hsa-miR-30e	CLIP-seq
MIRT2599887	hsa-miR-3123	CLIP-seq
MIRT2599888	hsa-miR-3135b	CLIP-seq
MIRT2599889	hsa-miR-3143	CLIP-seq
MIRT2599890	hsa-miR-3148	CLIP-seq
MIRT2599891	hsa-miR-3617	CLIP-seq
MIRT2599892	hsa-miR-3620	CLIP-seq
MIRT2599893	hsa-miR-3652	CLIP-seq
MIRT1259968	hsa-miR-3654	CLIP-seq
MIRT2457098	hsa-miR-375	CLIP-seq
MIRT2599894	hsa-miR-380	CLIP-seq
MIRT2599895	hsa-miR-381	CLIP-seq
MIRT2599896	hsa-miR-3913-3p	CLIP-seq
MIRT2599897	hsa-miR-3925-5p	CLIP-seq
MIRT2457099	hsa-miR-4273	CLIP-seq
MIRT2599898	hsa-miR-4279	CLIP-seq
MIRT2599899	hsa-miR-4282	CLIP-seq
MIRT2457100	hsa-miR-4292	CLIP-seq
MIRT2457101	hsa-miR-4308	CLIP-seq
MIRT2599900	hsa-miR-4430	CLIP-seq
MIRT2599901	hsa-miR-4474-3p	CLIP-seq
MIRT2599902	hsa-miR-4495	CLIP-seq
MIRT2599903	hsa-miR-4505	CLIP-seq
MIRT2599904	hsa-miR-4525	CLIP-seq
MIRT2599905	hsa-miR-4662a-3p	CLIP-seq
MIRT2599906	hsa-miR-4664-3p	CLIP-seq
MIRT2599907	hsa-miR-4665-5p	CLIP-seq
MIRT2599908	hsa-miR-4666-3p	CLIP-seq
MIRT1259980	hsa-miR-4668-5p	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT2599909	hsa-miR-4699-3p	CLIP-seq
MIRT2599910	hsa-miR-4723-5p	CLIP-seq
MIRT2599911	hsa-miR-4731-5p	CLIP-seq
MIRT2465902	hsa-miR-4753-3p	CLIP-seq
MIRT2599912	hsa-miR-4793-3p	CLIP-seq
MIRT2599913	hsa-miR-4803	CLIP-seq
MIRT2599914	hsa-miR-507	CLIP-seq
MIRT2599915	hsa-miR-518d-5p	CLIP-seq
MIRT2599916	hsa-miR-519b-5p	CLIP-seq
MIRT2599917	hsa-miR-519c-5p	CLIP-seq
MIRT2599918	hsa-miR-520c-5p	CLIP-seq
MIRT2599919	hsa-miR-526a	CLIP-seq
MIRT2599920	hsa-miR-543	CLIP-seq
MIRT2599921	hsa-miR-557	CLIP-seq
MIRT2599922	hsa-miR-577	CLIP-seq
MIRT1259988	hsa-miR-603	CLIP-seq
MIRT2599923	hsa-miR-625	CLIP-seq
MIRT2599924	hsa-miR-637	CLIP-seq
MIRT2599925	hsa-miR-641	CLIP-seq
MIRT2465901	hsa-miR-1236	CLIP-seq
MIRT2599877	hsa-miR-1275	CLIP-seq
MIRT2599878	hsa-miR-1287	CLIP-seq
MIRT2457097	hsa-miR-2117	CLIP-seq
MIRT2076573	hsa-miR-223	CLIP-seq
MIRT2599881	hsa-miR-3074-5p	CLIP-seq
MIRT2599882	hsa-miR-30a	CLIP-seq
MIRT2599883	hsa-miR-30b	CLIP-seq
MIRT2599884	hsa-miR-30c	CLIP-seq
MIRT2599885	hsa-miR-30d	CLIP-seq
MIRT2599886	hsa-miR-30e	CLIP-seq
MIRT2599887	hsa-miR-3123	CLIP-seq
MIRT2599888	hsa-miR-3135b	CLIP-seq
MIRT2599889	hsa-miR-3143	CLIP-seq
MIRT2599890	hsa-miR-3148	CLIP-seq
MIRT2599891	hsa-miR-3617	CLIP-seq
MIRT2457098	hsa-miR-375	CLIP-seq
MIRT2599894	hsa-miR-380	CLIP-seq
MIRT2599896	hsa-miR-3913-3p	CLIP-seq
MIRT2599897	hsa-miR-3925-5p	CLIP-seq
MIRT2457099	hsa-miR-4273	CLIP-seq
MIRT2599898	hsa-miR-4279	CLIP-seq
MIRT2457100	hsa-miR-4292	CLIP-seq
MIRT2457101	hsa-miR-4308	CLIP-seq
MIRT2599902	hsa-miR-4495	CLIP-seq
MIRT2599904	hsa-miR-4525	CLIP-seq
MIRT2599905	hsa-miR-4662a-3p	CLIP-seq
MIRT2599907	hsa-miR-4665-5p	CLIP-seq
MIRT1259980	hsa-miR-4668-5p	CLIP-seq
MIRT1259981	hsa-miR-4677-5p	CLIP-seq
MIRT2599909	hsa-miR-4699-3p	CLIP-seq
MIRT2599910	hsa-miR-4723-5p	CLIP-seq
MIRT2599911	hsa-miR-4731-5p	CLIP-seq
MIRT2465902	hsa-miR-4753-3p	CLIP-seq
MIRT2599912	hsa-miR-4793-3p	CLIP-seq
MIRT2599913	hsa-miR-4803	CLIP-seq
MIRT2599914	hsa-miR-507	CLIP-seq
MIRT2599915	hsa-miR-518d-5p	CLIP-seq
MIRT2599916	hsa-miR-519b-5p	CLIP-seq
MIRT2599917	hsa-miR-519c-5p	CLIP-seq
MIRT2599918	hsa-miR-520c-5p	CLIP-seq
MIRT2599919	hsa-miR-526a	CLIP-seq
MIRT2599920	hsa-miR-543	CLIP-seq
MIRT2599921	hsa-miR-557	CLIP-seq
MIRT2599922	hsa-miR-577	CLIP-seq
MIRT2599923	hsa-miR-625	CLIP-seq
MIRT2599924	hsa-miR-637	CLIP-seq
MIRT2599925	hsa-miR-641	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
CEBPB	Activation	19717648
PAX5	Repression	17682124;22593617
STAT3	Activation	1702555
STAT3	Unknown	12953803

Show/Hide all(25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	1851123
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	1851123
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	1851123
GO:0002250	Process	Adaptive immune response	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	22555612, 28842558, 32417234
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	28842558
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	21421998
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0008168	Function	Methyltransferase activity	IEA
GO:0010468	Process	Regulation of gene expression	IBA	21873635
GO:0032259	Process	Methylation	IEA
GO:0032823	Process	Regulation of natural killer cell differentiation	ISS
GO:0033082	Process	Regulation of extrathymic T cell differentiation	ISS
GO:0042826	Function	Histone deacetylase binding	IBA	21873635
GO:0045087	Process	Innate immune response	IEA
GO:0045165	Process	Cell fate commitment	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA
GO:0051136	Process	Regulation of NK T cell differentiation	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990841	Function	Promoter-specific chromatin binding	ISS

MIM	HGNC	e!Ensembl
603423	9346	ENSG00000057657

Protein

UniProt ID

O75626

Protein name

PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)

Protein function

Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negativ

PDB

3DAL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00856	SET	68 → 201	SET domain	Family
PF00096	zf-C2H2	575 → 597	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	603 → 625	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	631 → 656		Domain

Sequence

MLDICLEKRVGTTLAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTY
IVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEI
YTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGM
NIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCP
KNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYP
IRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTV
SPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGM
NCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQ
PEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAA
PSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGE
RPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQ
CKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPL
EDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNM
GNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP

Sequence length

825

Interactions

View interactions

	Reactome
			Regulation of TP53 Expression

Show/Hide Causal Diseases (4)

Disease term	Disease name	dbSNP ID	References
Causal
Diffuse lymphoma	Diffuse Large B-Cell Lymphoma	rs121912651, rs121913289, rs121913293, rs878854402, rs869025340, rs1349928568, rs1569115687, rs121913291
Inflammatory bowel disease	Inflammatory Bowel Diseases	rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468	26192919
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26974007
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	23143596, 19898481, 20453842

Show/Hide Unknown Diseases (8)

Disease term	Disease name	Evidence	References	Source
Unknown
Crohn disease	Crohn Disease		26974007	ClinVar
Crohn Disease	Crohn Disease			GWAS
Ulcerative colitis	Ulcerative colitis			GWAS
Inflammatory Bowel Disease	Inflammatory Bowel Disease			GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus			GWAS
Acne	Acne			GWAS
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.		GWAS, CBGDA
Insomnia	Insomnia			GWAS

Show/Hide Text Mining Associations (80)

Disease Name	Relationship Type	References
Associations from Text Mining
Arthralgia	Stimulate	29720240
Arthritis	Stimulate	29720240
Arthritis Rheumatoid	Associate	19898481
Arthritis Rheumatoid	Stimulate	29720240
Breast Neoplasms	Associate	19433448, 34907035
Burkitt Lymphoma	Associate	25382611
Carcinogenesis	Inhibit	28468592
Carcinoma Embryonal	Inhibit	18992153
Carcinoma Hepatocellular	Associate	35382824
Carcinoma Non Small Cell Lung	Associate	25635434
Carcinoma Renal Cell	Associate	27144525, 35308143
Colonic Neoplasms	Inhibit	29760071
Colorectal Neoplasms	Associate	28675510, 29760071
Colorectal Neoplasms	Stimulate	32393998
Common Variable Immunodeficiency	Stimulate	33463110
Common Variable Immunodeficiency	Associate	34920653
COVID 19	Associate	35528178
Crohn Disease	Associate	23624108
Depressive Disorder	Associate	32998701
Drug Related Side Effects and Adverse Reactions	Inhibit	28629373
Endometriosis	Associate	28300844
Epstein Barr Virus Infections	Stimulate	22711707
Epstein Barr Virus Infections	Associate	32273478
GATA2 Deficiency	Associate	21690554, 22143801, 22922206, 25203537, 28468592, 32732362
Graft vs Host Disease	Associate	35572579
Hereditary leiomyomatosis and renal cell cancer	Associate	18583325
HIV Infections	Associate	23129528
Hodgkin Disease	Inhibit	18583325, 25232062
Hodgkin Disease	Associate	21785431, 23089009, 24306881, 26530011
Immunoglobulin G4 Related Disease	Associate	37561593
Infections	Stimulate	35417711
Inflammation	Associate	33976194, 35486677
Inflammatory Bowel Diseases	Associate	23028907, 24487271
Leukemia	Associate	17374122
Leukemia B Cell	Associate	20651244
Leukemia Large Granular Lymphocytic	Associate	24438193, 26221594
Leukemia Lymphocytic Chronic B Cell	Associate	24637363
Leukemia Lymphocytic Chronic B Cell	Stimulate	30654767
Leukemia Lymphoma Adult T Cell	Associate	33426772
Leukemia Myeloid Acute	Associate	19666867, 28629373
Leukoplakia Hairy	Associate	25410866, 26431332
Lupus Erythematosus Systemic	Associate	19838195
Lymphedema	Associate	11841448
Lymphoma	Associate	17379744, 19828640, 25991819, 32985591, 37657032
Lymphoma B Cell	Inhibit	16492805, 29760071
Lymphoma B Cell	Associate	20418245, 20966935, 24030746
Lymphoma B Cell Marginal Zone	Associate	16778825
Lymphoma Extranodal NK T Cell	Associate	24438193, 26221594, 31002364
Lymphoma Follicular	Associate	22102710, 30348636
Lymphoma Large B Cell Diffuse	Associate	16424392, 16492805, 17379744, 18583325, 20418245, 20651244, 20800019, 21722313, 23789844, 25382611, 25991819, 27224915, 28479318, 37730436
Lymphoma Large B Cell Diffuse	Inhibit	26530011, 27568520
Lymphoma Mantle Cell	Associate	20530581, 26360498
Lymphoma Primary Cutaneous Anaplastic Large Cell	Associate	34382383
Lymphoma Primary Effusion	Associate	26625717
Lymphoma T Cell	Associate	18235046
Macular Edema	Associate	31968263
Multiple Myeloma	Associate	12453881, 16765445, 17300840, 25743686, 26823144, 28052011, 29654271, 29789651, 32070879, 32765503, 32985591, 37452600
Nasopharyngeal Carcinoma	Stimulate	25410866
Neoplasms	Inhibit	16424392, 16492805, 20651244, 21690554, 21722313, 22143801, 24438193, 25203537, 25382611, 26530011, 27568520, 28468592, 29760071, 31002364, 32732362, 32985591 View all (1 more)
Neoplasms	Associate	18583325, 21785431, 23089009, 23599149, 24306881, 25578962, 28494239, 32070879, 34382383, 35087134, 36670235, 37730436
Neoplasms Germ Cell and Embryonal	Associate	18992153
Neoplasms Plasma Cell	Associate	26823144
Neoplasms Second Primary	Associate	21785431, 24306881
Nonseminomatous germ cell tumor	Inhibit	18992153
Paraproteinemias	Associate	36138464
Plasmablastic Lymphoma	Associate	20418245, 27687004, 32273478
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	36670235
Primary Ovarian Insufficiency	Associate	36732629
Purpura Thrombocytopenic Idiopathic	Associate	30383696
Purpura Thrombocytopenic Idiopathic	Inhibit	37208911
Pyoderma Gangrenosum	Associate	24487271
Pyruvate Carboxylase Deficiency Disease	Associate	19846886, 33133085
Radiation Injuries	Associate	23089009
Seminoma	Associate	18992153
Sjogren's Syndrome	Associate	35896530
Stomach Neoplasms	Stimulate	25410866
T cell immunodeficiency primary	Associate	23129528
Thyroid Neoplasms	Associate	36930113
Tn Syndrome	Inhibit	29892290
Tuberculosis	Associate	33763081

PRDM1 (PR/SET domain 1)