CCL22 (C-C motif chemokine ligand 22)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6367 |
| Gene name | C-C motif chemokine ligand 22 |
| Gene symbol | CCL22 |
| Synonyms (NCBI Gene) |
A-152E5.1ABCD-1DC/B-CKMDCSCYA22STCP-1
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| Chromosome | 16 |
| Chromosome location | 16q21 |
| Summary | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized |
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miRNA
miRNA information provided by mirtarbase database.
602
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
2
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O00626 | ||||||||||
| Protein name | C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] | ||||||||||
| Protein function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for pr | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression i | ||||||||||
| Sequence |
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| Sequence length | 93 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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