CCL4 (C-C motif chemokine ligand 4)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6351
Gene name Gene Name - the full gene name approved by the HGNC.
C-C motif chemokine ligand 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CCL4
Synonyms (NCBI Gene) Gene synonyms aliases
ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q12
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT004669 hsa-miR-195-5p ELISA, Immunoprecipitaion, qRT-PCR, Western blot 20952681
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(3)
Transcription factor Regulation Reference
CREM Repression 16443828
NFKB1 Unknown 11342414
RELA Unknown 11342414
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(34)
GO ID Ontology Definition Evidence Reference
GO:0002548 Process Monocyte chemotaxis IBA 21873635
GO:0005125 Function Cytokine activity TAS 2462251
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183
GO:0005576 Component Extracellular region TAS
GO:0005615 Component Extracellular space IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
182284 10630 ENSG00000275302
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
  KEGG   Reactome
  Cytokine-cytokine receptor interaction
Viral protein interaction with cytokine and cytokine receptor
Chemokine signaling pathway
NF-kappa B signaling pathway
Toll-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Human cytomegalovirus infection 		  Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Glomerulonephritis Glomerulonephritis rs778043831 10385480
Pulmonary fibrosis Pulmonary Fibrosis rs121918666, rs199422300, rs121917834, rs199422294, rs201159197, rs199422297, rs199422305, rs751381953, rs876661305, rs878853260, rs1555811762, rs1060502990, rs1555903332, rs1554038539, rs1554042899
View all (1 more)		 17720292
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Atherosclerosis Atherosclerosis 24370436 ClinVar
Show/Hide Text Mining Associations (229)
Associations from Text Mining
Disease Name Relationship Type References
Acquired Immunodeficiency Syndrome Associate 16773571, 8986820, 9420304
Acute Disease Associate 21347345, 34607465
Acute On Chronic Liver Failure Associate 36626090
Adenocarcinoma Stimulate 31385574
Adenocarcinoma of Lung Stimulate 29722145
AIDS Dementia Complex Stimulate 8570619
AIDS Dementia Complex Associate 8784788
Allan Herndon Dudley syndrome Stimulate 24768357
Alzheimer Disease Associate 32171317, 9665462
Anemia Inhibit 12853396