SCN2B (sodium voltage-gated channel beta subunit 2)

Gene

• Entrez ID: 6327
• Gene name: Sodium voltage-gated channel beta subunit 2
• Gene symbol: SCN2B
• Synonyms (NCBI Gene): ATFB14
• Chromosome: 11
• Chromosome location: 11q23.3
• Summary: The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs17121819	G>A	Pathogenic, uncertain-significance	Coding sequence variant, missense variant
rs72544145	C>T	Pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT699822	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT699821	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT699820	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT699819	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT699818	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT699817	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT699816	hsa-miR-1976	HITS-CLIP	23313552
MIRT699815	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT699814	hsa-miR-4279	HITS-CLIP	23313552
MIRT699813	hsa-miR-5585-3p	HITS-CLIP	23313552
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641417	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT641416	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641406	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT641405	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT654020	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT654019	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT654018	hsa-miR-4421	HITS-CLIP	23824327
MIRT654016	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT654017	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT654015	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT654014	hsa-miR-7975	HITS-CLIP	23824327
MIRT654013	hsa-miR-3685	HITS-CLIP	23824327
MIRT654012	hsa-miR-384	HITS-CLIP	23824327
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641417	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT641416	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641406	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT641405	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT500043	hsa-miR-4708-3p	HITS-CLIP	23824327
MIRT500042	hsa-miR-4746-3p	HITS-CLIP	23824327
MIRT570100	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT570099	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT570098	hsa-miR-4489	PAR-CLIP	20371350
MIRT570097	hsa-miR-4283	PAR-CLIP	20371350
MIRT570096	hsa-miR-185-3p	PAR-CLIP	20371350
MIRT570095	hsa-miR-3151-5p	PAR-CLIP	20371350
MIRT570094	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	20371350
MIRT570100	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT570099	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT570098	hsa-miR-4489	PAR-CLIP	20371350
MIRT570097	hsa-miR-4283	PAR-CLIP	20371350
MIRT570096	hsa-miR-185-3p	PAR-CLIP	20371350
MIRT570095	hsa-miR-3151-5p	PAR-CLIP	20371350
MIRT570094	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	22012620
MIRT500043	hsa-miR-4708-3p	PAR-CLIP	24398324
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	24398324
MIRT641411	hsa-miR-1273f	HITS-CLIP	27418678
MIRT641408	hsa-miR-1289	HITS-CLIP	27418678
MIRT641408	hsa-miR-1289	HITS-CLIP	27418678
MIRT641401	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT641415	hsa-miR-143-3p	HITS-CLIP	27418678
MIRT641415	hsa-miR-143-3p	HITS-CLIP	27418678
MIRT641404	hsa-miR-3198	HITS-CLIP	27418678
MIRT641404	hsa-miR-3198	HITS-CLIP	27418678
MIRT641407	hsa-miR-4294	HITS-CLIP	27418678
MIRT641407	hsa-miR-4294	HITS-CLIP	27418678
MIRT641403	hsa-miR-4309	HITS-CLIP	27418678
MIRT641403	hsa-miR-4309	HITS-CLIP	27418678
MIRT641410	hsa-miR-4534	HITS-CLIP	27418678
MIRT641410	hsa-miR-4534	HITS-CLIP	27418678
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	27418678
MIRT641414	hsa-miR-4770	HITS-CLIP	27418678
MIRT641414	hsa-miR-4770	HITS-CLIP	27418678
MIRT641413	hsa-miR-6088	HITS-CLIP	27418678
MIRT641413	hsa-miR-6088	HITS-CLIP	27418678
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	27418678
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	27418678
MIRT641416	hsa-miR-6817-3p	HITS-CLIP	27418678
MIRT641405	hsa-miR-6873-3p	HITS-CLIP	27418678
MIRT641406	hsa-miR-6895-3p	HITS-CLIP	27418678
MIRT641417	hsa-miR-7110-3p	HITS-CLIP	27418678
MIRT641402	hsa-miR-8055	HITS-CLIP	27418678
MIRT641402	hsa-miR-8055	HITS-CLIP	27418678
MIRT641409	hsa-miR-8082	HITS-CLIP	27418678
MIRT641409	hsa-miR-8082	HITS-CLIP	27418678
MIRT699822	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT699821	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT699820	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT699819	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT699818	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT699817	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT699816	hsa-miR-1976	HITS-CLIP	23313552
MIRT699815	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT699814	hsa-miR-4279	HITS-CLIP	23313552
MIRT699813	hsa-miR-5585-3p	HITS-CLIP	23313552
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641417	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT641416	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641406	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT641405	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT654020	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT654019	hsa-miR-6748-3p	HITS-CLIP	23824327
MIRT654018	hsa-miR-4421	HITS-CLIP	23824327
MIRT654016	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT654017	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT654015	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT654014	hsa-miR-7975	HITS-CLIP	23824327
MIRT654013	hsa-miR-3685	HITS-CLIP	23824327
MIRT654012	hsa-miR-384	HITS-CLIP	23824327
MIRT641418	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT641417	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT641416	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT641415	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT641414	hsa-miR-4770	HITS-CLIP	23824327
MIRT641413	hsa-miR-6088	HITS-CLIP	23824327
MIRT641412	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT641411	hsa-miR-1273f	HITS-CLIP	23824327
MIRT641410	hsa-miR-4534	HITS-CLIP	23824327
MIRT641409	hsa-miR-8082	HITS-CLIP	23824327
MIRT641408	hsa-miR-1289	HITS-CLIP	23824327
MIRT641407	hsa-miR-4294	HITS-CLIP	23824327
MIRT641406	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT641405	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT641404	hsa-miR-3198	HITS-CLIP	23824327
MIRT641403	hsa-miR-4309	HITS-CLIP	23824327
MIRT641402	hsa-miR-8055	HITS-CLIP	23824327
MIRT641401	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT500043	hsa-miR-4708-3p	HITS-CLIP	23824327
MIRT500042	hsa-miR-4746-3p	HITS-CLIP	23824327
MIRT570100	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT570099	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT570098	hsa-miR-4489	PAR-CLIP	20371350
MIRT570097	hsa-miR-4283	PAR-CLIP	20371350
MIRT570096	hsa-miR-185-3p	PAR-CLIP	20371350
MIRT570095	hsa-miR-3151-5p	PAR-CLIP	20371350
MIRT570094	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	20371350
MIRT570100	hsa-miR-1296-3p	PAR-CLIP	20371350
MIRT570099	hsa-miR-4795-5p	PAR-CLIP	20371350
MIRT570098	hsa-miR-4489	PAR-CLIP	20371350
MIRT570097	hsa-miR-4283	PAR-CLIP	20371350
MIRT570096	hsa-miR-185-3p	PAR-CLIP	20371350
MIRT570095	hsa-miR-3151-5p	PAR-CLIP	20371350
MIRT570094	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	22012620
MIRT500043	hsa-miR-4708-3p	PAR-CLIP	24398324
MIRT500042	hsa-miR-4746-3p	PAR-CLIP	24398324
MIRT1329822	hsa-miR-1	CLIP-seq
MIRT1329823	hsa-miR-106a	CLIP-seq
MIRT1329824	hsa-miR-106b	CLIP-seq
MIRT1329825	hsa-miR-1179	CLIP-seq
MIRT1329826	hsa-miR-1205	CLIP-seq
MIRT1329827	hsa-miR-1207-5p	CLIP-seq
MIRT1329828	hsa-miR-1208	CLIP-seq
MIRT1329829	hsa-miR-1229	CLIP-seq
MIRT1329830	hsa-miR-1233	CLIP-seq
MIRT1329831	hsa-miR-1254	CLIP-seq
MIRT1329832	hsa-miR-1275	CLIP-seq
MIRT1329833	hsa-miR-129-3p	CLIP-seq
MIRT1329834	hsa-miR-1343	CLIP-seq
MIRT1329835	hsa-miR-149	CLIP-seq
MIRT1329836	hsa-miR-150	CLIP-seq
MIRT1329837	hsa-miR-17	CLIP-seq
MIRT1329838	hsa-miR-1827	CLIP-seq
MIRT1329839	hsa-miR-188-5p	CLIP-seq
MIRT1329840	hsa-miR-1909	CLIP-seq
MIRT1329841	hsa-miR-1913	CLIP-seq
MIRT1329842	hsa-miR-204	CLIP-seq
MIRT1329843	hsa-miR-206	CLIP-seq
MIRT1329844	hsa-miR-20a	CLIP-seq
MIRT1329845	hsa-miR-20b	CLIP-seq
MIRT1329846	hsa-miR-211	CLIP-seq
MIRT1329847	hsa-miR-219-2-3p	CLIP-seq
MIRT1329848	hsa-miR-2392	CLIP-seq
MIRT1329849	hsa-miR-24	CLIP-seq
MIRT1329850	hsa-miR-2467-5p	CLIP-seq
MIRT1329851	hsa-miR-2964a-3p	CLIP-seq
MIRT1329852	hsa-miR-302a	CLIP-seq
MIRT1329853	hsa-miR-302b	CLIP-seq
MIRT1329854	hsa-miR-302c	CLIP-seq
MIRT1329855	hsa-miR-302d	CLIP-seq
MIRT1329856	hsa-miR-302e	CLIP-seq
MIRT1329857	hsa-miR-3064-5p	CLIP-seq
MIRT1329858	hsa-miR-3065-3p	CLIP-seq
MIRT1329859	hsa-miR-3074-5p	CLIP-seq
MIRT1329860	hsa-miR-3116	CLIP-seq
MIRT1329861	hsa-miR-3140-3p	CLIP-seq
MIRT1329862	hsa-miR-3141	CLIP-seq
MIRT1329863	hsa-miR-3143	CLIP-seq
MIRT1329864	hsa-miR-3176	CLIP-seq
MIRT1329865	hsa-miR-3180-5p	CLIP-seq
MIRT1329866	hsa-miR-3184	CLIP-seq
MIRT1329867	hsa-miR-3192	CLIP-seq
MIRT1329868	hsa-miR-324-3p	CLIP-seq
MIRT1329869	hsa-miR-335	CLIP-seq
MIRT1329870	hsa-miR-3612	CLIP-seq
MIRT1329871	hsa-miR-3652	CLIP-seq
MIRT1329872	hsa-miR-3665	CLIP-seq
MIRT1329873	hsa-miR-3673	CLIP-seq
MIRT1329874	hsa-miR-3679-3p	CLIP-seq
MIRT1329875	hsa-miR-3689a-3p	CLIP-seq
MIRT1329876	hsa-miR-3689c	CLIP-seq
MIRT1329877	hsa-miR-3691-3p	CLIP-seq
MIRT1329878	hsa-miR-372	CLIP-seq
MIRT1329879	hsa-miR-373	CLIP-seq
MIRT1329880	hsa-miR-378g	CLIP-seq
MIRT1329881	hsa-miR-3918	CLIP-seq
MIRT1329882	hsa-miR-3922-3p	CLIP-seq
MIRT1329883	hsa-miR-3929	CLIP-seq
MIRT1329884	hsa-miR-423-5p	CLIP-seq
MIRT1329885	hsa-miR-4252	CLIP-seq
MIRT1329886	hsa-miR-4263	CLIP-seq
MIRT1329887	hsa-miR-4268	CLIP-seq
MIRT1329888	hsa-miR-4269	CLIP-seq
MIRT1329889	hsa-miR-4274	CLIP-seq
MIRT1329890	hsa-miR-4284	CLIP-seq
MIRT1329891	hsa-miR-4300	CLIP-seq
MIRT1329892	hsa-miR-4323	CLIP-seq
MIRT1329893	hsa-miR-4419b	CLIP-seq
MIRT1329894	hsa-miR-4420	CLIP-seq
MIRT1329895	hsa-miR-4430	CLIP-seq
MIRT1329896	hsa-miR-4437	CLIP-seq
MIRT1329897	hsa-miR-4438	CLIP-seq
MIRT1329898	hsa-miR-4446-5p	CLIP-seq
MIRT1329899	hsa-miR-4478	CLIP-seq
MIRT1329900	hsa-miR-4492	CLIP-seq
MIRT1329901	hsa-miR-4498	CLIP-seq
MIRT1329902	hsa-miR-4505	CLIP-seq
MIRT1329903	hsa-miR-4514	CLIP-seq
MIRT1329904	hsa-miR-4525	CLIP-seq
MIRT1329905	hsa-miR-4530	CLIP-seq
MIRT1329906	hsa-miR-4660	CLIP-seq
MIRT1329907	hsa-miR-4665-5p	CLIP-seq
MIRT1329908	hsa-miR-4674	CLIP-seq
MIRT1329909	hsa-miR-4680-3p	CLIP-seq
MIRT1329910	hsa-miR-4681	CLIP-seq
MIRT1329911	hsa-miR-4692	CLIP-seq
MIRT1329912	hsa-miR-4709-3p	CLIP-seq
MIRT1329913	hsa-miR-4723-5p	CLIP-seq
MIRT1329914	hsa-miR-4728-5p	CLIP-seq
MIRT1329915	hsa-miR-4731-5p	CLIP-seq
MIRT1329916	hsa-miR-4736	CLIP-seq
MIRT1329917	hsa-miR-4749-3p	CLIP-seq
MIRT1329918	hsa-miR-4763-3p	CLIP-seq
MIRT1329919	hsa-miR-4768-5p	CLIP-seq
MIRT1329920	hsa-miR-4786-3p	CLIP-seq
MIRT1329921	hsa-miR-4793-5p	CLIP-seq
MIRT1329922	hsa-miR-485-5p	CLIP-seq
MIRT1329923	hsa-miR-5095	CLIP-seq
MIRT1329924	hsa-miR-512-3p	CLIP-seq
MIRT1329925	hsa-miR-518a-3p	CLIP-seq
MIRT1329926	hsa-miR-518b	CLIP-seq
MIRT1329927	hsa-miR-518c	CLIP-seq
MIRT1329928	hsa-miR-518d-3p	CLIP-seq
MIRT1329929	hsa-miR-518f	CLIP-seq
MIRT1329930	hsa-miR-519a	CLIP-seq
MIRT1329931	hsa-miR-519b-3p	CLIP-seq
MIRT1329932	hsa-miR-519c-3p	CLIP-seq
MIRT1329933	hsa-miR-519d	CLIP-seq
MIRT1329934	hsa-miR-520a-3p	CLIP-seq
MIRT1329935	hsa-miR-520a-5p	CLIP-seq
MIRT1329936	hsa-miR-520b	CLIP-seq
MIRT1329937	hsa-miR-520c-3p	CLIP-seq
MIRT1329938	hsa-miR-520d-3p	CLIP-seq
MIRT1329939	hsa-miR-520e	CLIP-seq
MIRT1329940	hsa-miR-520g	CLIP-seq
MIRT1329941	hsa-miR-520h	CLIP-seq
MIRT1329942	hsa-miR-525-5p	CLIP-seq
MIRT1329943	hsa-miR-550a	CLIP-seq
MIRT1329944	hsa-miR-578	CLIP-seq
MIRT1329945	hsa-miR-604	CLIP-seq
MIRT1329946	hsa-miR-613	CLIP-seq
MIRT1329947	hsa-miR-625	CLIP-seq
MIRT1329948	hsa-miR-637	CLIP-seq
MIRT1329949	hsa-miR-643	CLIP-seq
MIRT1329950	hsa-miR-647	CLIP-seq
MIRT1329951	hsa-miR-650	CLIP-seq
MIRT1329952	hsa-miR-661	CLIP-seq
MIRT1329953	hsa-miR-762	CLIP-seq
MIRT1329954	hsa-miR-885-3p	CLIP-seq
MIRT1329955	hsa-miR-920	CLIP-seq
MIRT1329956	hsa-miR-93	CLIP-seq
MIRT1329957	hsa-miR-940	CLIP-seq
MIRT1329916	hsa-miR-4736	CLIP-seq
MIRT1329919	hsa-miR-4768-5p	CLIP-seq
MIRT2097760	hsa-miR-1207-3p	CLIP-seq
MIRT1329831	hsa-miR-1254	CLIP-seq
MIRT2097761	hsa-miR-128	CLIP-seq
MIRT1329840	hsa-miR-1909	CLIP-seq
MIRT1329841	hsa-miR-1913	CLIP-seq
MIRT2097762	hsa-miR-1972	CLIP-seq
MIRT1329847	hsa-miR-219-2-3p	CLIP-seq
MIRT2097763	hsa-miR-2467-3p	CLIP-seq
MIRT1329851	hsa-miR-2964a-3p	CLIP-seq
MIRT1329852	hsa-miR-302a	CLIP-seq
MIRT1329853	hsa-miR-302b	CLIP-seq
MIRT1329854	hsa-miR-302c	CLIP-seq
MIRT1329855	hsa-miR-302d	CLIP-seq
MIRT1329856	hsa-miR-302e	CLIP-seq
MIRT1329860	hsa-miR-3116	CLIP-seq
MIRT2097764	hsa-miR-3125	CLIP-seq
MIRT1329864	hsa-miR-3176	CLIP-seq
MIRT2097765	hsa-miR-3183	CLIP-seq
MIRT1329868	hsa-miR-324-3p	CLIP-seq
MIRT2097766	hsa-miR-34c-3p	CLIP-seq
MIRT1329878	hsa-miR-372	CLIP-seq
MIRT1329879	hsa-miR-373	CLIP-seq
MIRT2097767	hsa-miR-3916	CLIP-seq
MIRT1329881	hsa-miR-3918	CLIP-seq
MIRT1329882	hsa-miR-3922-3p	CLIP-seq
MIRT1329883	hsa-miR-3929	CLIP-seq
MIRT2097768	hsa-miR-4264	CLIP-seq
MIRT2097769	hsa-miR-4313	CLIP-seq
MIRT1329893	hsa-miR-4419b	CLIP-seq
MIRT2097770	hsa-miR-4476	CLIP-seq
MIRT1329899	hsa-miR-4478	CLIP-seq
MIRT1329902	hsa-miR-4505	CLIP-seq
MIRT2097771	hsa-miR-4511	CLIP-seq
MIRT2097772	hsa-miR-451b	CLIP-seq
MIRT2097773	hsa-miR-4667-3p	CLIP-seq
MIRT1329909	hsa-miR-4680-3p	CLIP-seq
MIRT2097774	hsa-miR-4723-3p	CLIP-seq
MIRT1329915	hsa-miR-4731-5p	CLIP-seq
MIRT2097775	hsa-miR-4757-5p	CLIP-seq
MIRT1329924	hsa-miR-512-3p	CLIP-seq
MIRT1329934	hsa-miR-520a-3p	CLIP-seq
MIRT1329936	hsa-miR-520b	CLIP-seq
MIRT1329937	hsa-miR-520c-3p	CLIP-seq
MIRT1329938	hsa-miR-520d-3p	CLIP-seq
MIRT1329939	hsa-miR-520e	CLIP-seq
MIRT1329943	hsa-miR-550a	CLIP-seq
MIRT1329944	hsa-miR-578	CLIP-seq
MIRT2097776	hsa-miR-622	CLIP-seq
MIRT1329952	hsa-miR-661	CLIP-seq
MIRT1329823	hsa-miR-106a	CLIP-seq
MIRT1329824	hsa-miR-106b	CLIP-seq
MIRT1329827	hsa-miR-1207-5p	CLIP-seq
MIRT1329831	hsa-miR-1254	CLIP-seq
MIRT1329836	hsa-miR-150	CLIP-seq
MIRT1329837	hsa-miR-17	CLIP-seq
MIRT1329840	hsa-miR-1909	CLIP-seq
MIRT1329844	hsa-miR-20a	CLIP-seq
MIRT1329845	hsa-miR-20b	CLIP-seq
MIRT2322059	hsa-miR-2115	CLIP-seq
MIRT2097763	hsa-miR-2467-3p	CLIP-seq
MIRT1329852	hsa-miR-302a	CLIP-seq
MIRT1329853	hsa-miR-302b	CLIP-seq
MIRT1329854	hsa-miR-302c	CLIP-seq
MIRT1329855	hsa-miR-302d	CLIP-seq
MIRT1329856	hsa-miR-302e	CLIP-seq
MIRT1329860	hsa-miR-3116	CLIP-seq
MIRT1329864	hsa-miR-3176	CLIP-seq
MIRT1329867	hsa-miR-3192	CLIP-seq
MIRT2322060	hsa-miR-3678-3p	CLIP-seq
MIRT1329878	hsa-miR-372	CLIP-seq
MIRT1329879	hsa-miR-373	CLIP-seq
MIRT1329882	hsa-miR-3922-3p	CLIP-seq
MIRT1329885	hsa-miR-4252	CLIP-seq
MIRT1329888	hsa-miR-4269	CLIP-seq
MIRT2322061	hsa-miR-431	CLIP-seq
MIRT1329896	hsa-miR-4437	CLIP-seq
MIRT1329897	hsa-miR-4438	CLIP-seq
MIRT2322062	hsa-miR-4532	CLIP-seq
MIRT2322063	hsa-miR-4694-3p	CLIP-seq
MIRT2322064	hsa-miR-4711-3p	CLIP-seq
MIRT1329915	hsa-miR-4731-5p	CLIP-seq
MIRT2097775	hsa-miR-4757-5p	CLIP-seq
MIRT1329918	hsa-miR-4763-3p	CLIP-seq
MIRT2322065	hsa-miR-4772-3p	CLIP-seq
MIRT1329923	hsa-miR-5095	CLIP-seq
MIRT1329924	hsa-miR-512-3p	CLIP-seq
MIRT2322066	hsa-miR-516a-3p	CLIP-seq
MIRT1329925	hsa-miR-518a-3p	CLIP-seq
MIRT1329926	hsa-miR-518b	CLIP-seq
MIRT1329927	hsa-miR-518c	CLIP-seq
MIRT1329928	hsa-miR-518d-3p	CLIP-seq
MIRT1329929	hsa-miR-518f	CLIP-seq
MIRT1329933	hsa-miR-519d	CLIP-seq
MIRT1329934	hsa-miR-520a-3p	CLIP-seq
MIRT1329936	hsa-miR-520b	CLIP-seq
MIRT1329937	hsa-miR-520c-3p	CLIP-seq
MIRT1329938	hsa-miR-520d-3p	CLIP-seq
MIRT1329939	hsa-miR-520e	CLIP-seq
MIRT1329940	hsa-miR-520g	CLIP-seq
MIRT1329941	hsa-miR-520h	CLIP-seq
MIRT2322067	hsa-miR-522	CLIP-seq
MIRT1329943	hsa-miR-550a	CLIP-seq
MIRT1329952	hsa-miR-661	CLIP-seq
MIRT1329956	hsa-miR-93	CLIP-seq
MIRT1329831	hsa-miR-1254	CLIP-seq
MIRT1329847	hsa-miR-219-2-3p	CLIP-seq
MIRT1329851	hsa-miR-2964a-3p	CLIP-seq
MIRT1329860	hsa-miR-3116	CLIP-seq
MIRT1329864	hsa-miR-3176	CLIP-seq
MIRT1329882	hsa-miR-3922-3p	CLIP-seq
MIRT1329883	hsa-miR-3929	CLIP-seq
MIRT1329885	hsa-miR-4252	CLIP-seq
MIRT1329893	hsa-miR-4419b	CLIP-seq
MIRT1329897	hsa-miR-4438	CLIP-seq
MIRT1329899	hsa-miR-4478	CLIP-seq
MIRT1329909	hsa-miR-4680-3p	CLIP-seq
MIRT2322063	hsa-miR-4694-3p	CLIP-seq
MIRT1329923	hsa-miR-5095	CLIP-seq
MIRT2322067	hsa-miR-522	CLIP-seq
MIRT1329943	hsa-miR-550a	CLIP-seq
MIRT1329952	hsa-miR-661	CLIP-seq
MIRT2458936	hsa-miR-1197	CLIP-seq
MIRT2458937	hsa-miR-3151	CLIP-seq
MIRT2458938	hsa-miR-4436a	CLIP-seq
MIRT1329917	hsa-miR-4749-3p	CLIP-seq
MIRT2458936	hsa-miR-1197	CLIP-seq
MIRT2458938	hsa-miR-4436a	CLIP-seq
MIRT1329917	hsa-miR-4749-3p	CLIP-seq
MIRT2458936	hsa-miR-1197	CLIP-seq
MIRT2097763	hsa-miR-2467-3p	CLIP-seq
MIRT2097764	hsa-miR-3125	CLIP-seq
MIRT2618483	hsa-miR-3127-5p	CLIP-seq
MIRT2618484	hsa-miR-3148	CLIP-seq
MIRT2618485	hsa-miR-383	CLIP-seq
MIRT2097767	hsa-miR-3916	CLIP-seq
MIRT1329881	hsa-miR-3918	CLIP-seq
MIRT1329888	hsa-miR-4269	CLIP-seq
MIRT2458938	hsa-miR-4436a	CLIP-seq
MIRT2618486	hsa-miR-4436b-3p	CLIP-seq
MIRT1329897	hsa-miR-4438	CLIP-seq
MIRT1329917	hsa-miR-4749-3p	CLIP-seq
MIRT2618487	hsa-miR-4772-5p	CLIP-seq
MIRT1329923	hsa-miR-5095	CLIP-seq
MIRT2458936	hsa-miR-1197	CLIP-seq
MIRT2458938	hsa-miR-4436a	CLIP-seq
MIRT1329917	hsa-miR-4749-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001518	Component	Voltage-gated sodium channel complex	IBA
GO:0001518	Component	Voltage-gated sodium channel complex	IDA	19808477, 35277491, 36823201
GO:0001518	Component	Voltage-gated sodium channel complex	TAS	9295116
GO:0005248	Function	Voltage-gated sodium channel activity	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	35277491
GO:0005886	Component	Plasma membrane	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006814	Process	Sodium ion transport	IEA
GO:0006814	Process	Sodium ion transport	IEA
GO:0007268	Process	Chemical synaptic transmission	TAS	9295116
GO:0007399	Process	Nervous system development	IEA
GO:0009408	Process	Response to heat	IEA
GO:0010467	Process	Gene expression	IEA
GO:0010765	Process	Positive regulation of sodium ion transport	IDA	19808477
GO:0016020	Component	Membrane	IEA
GO:0017080	Function	Sodium channel regulator activity	IBA
GO:0017080	Function	Sodium channel regulator activity	IDA	19808477
GO:0017080	Function	Sodium channel regulator activity	IEA
GO:0030315	Component	T-tubule	IEA
GO:0030424	Component	Axon	IEA
GO:0033268	Component	Node of Ranvier	IEA
GO:0035725	Process	Sodium ion transmembrane transport	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043194	Component	Axon initial segment	IEA
GO:0045202	Component	Synapse	IEA
GO:0046684	Process	Response to pyrethroid	IEA
GO:0060048	Process	Cardiac muscle contraction	IMP	19808477
GO:0060371	Process	Regulation of atrial cardiac muscle cell membrane depolarization	IMP	19808477
GO:0061337	Process	Cardiac conduction	IBA
GO:0061337	Process	Cardiac conduction	IEA
GO:0086002	Process	Cardiac muscle cell action potential involved in contraction	IBA
GO:0086002	Process	Cardiac muscle cell action potential involved in contraction	IMP	19808477
GO:0086006	Function	Voltage-gated sodium channel activity involved in cardiac muscle cell action potential	IEA
GO:0086010	Process	Membrane depolarization during action potential	IDA	35277491
GO:0086012	Process	Membrane depolarization during cardiac muscle cell action potential	IBA
GO:0086012	Process	Membrane depolarization during cardiac muscle cell action potential	IMP	19808477
GO:0086091	Process	Regulation of heart rate by cardiac conduction	IMP	19808477
GO:0098915	Process	Membrane repolarization during ventricular cardiac muscle cell action potential	IEA
GO:1902282	Function	Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	IEA

Other IDs

• MIM: 601327
• HGNC: 10589
• e!Ensembl: ENSG00000149575

Protein

• UniProt ID: O60939
• Protein name: Sodium channel regulatory subunit beta-2
• Protein function: Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes (PubMed:19808477, PubMed:23559163, PubMed:26894959, PubMed:30765605, PubMed:30765606, PubMed:35277491, PubMed:3682320
• PDB: 5FDY, 5FEB, 6J8E, 6J8G, 6J8H, 6J8I, 6J8J, 6VRR, 7W77, 7W7F, 7W9K, 7W9L, 7W9M, 7W9P, 7W9T, 7XM9, 7XMF, 7XMG, 7XVE, 7XVF, 8G1A, 8GZ1, 8GZ2, 8I5B, 8I5G, 8I5X, 8I5Y, 8S9B, 8S9C, 8THG, 8THH, 8XMN, 8XMO
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07686	V-set	33 → 147	Immunoglobulin V-set domain	Domain

• Sequence:

  MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNH
  KQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPE
  DEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVV
  KCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK

• Sequence length: 215

Pathways

Reactome:

Phase 0 - rapid depolarisation

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Atrial fibrillation, familial, 14	Uncertain significance; Likely benign; Benign; Conflicting classifications of pathogenicity	rs1948399832, rs142643516, rs771234231, rs371409245, rs1326811641, rs1217452578, rs1336662030, rs752863331, rs751230713, rs981151593, rs376336851, rs369244943, rs765701955, rs552421963, rs750313446, rs765542447, rs1316023322, rs2135518217, rs772817742, rs761979593, rs758238682, rs1948399268, rs1024654954, rs1192595114, rs2135518443, rs1591444155, rs1478317204, rs776528668, rs961279155, rs2135517512, rs140314864, rs757644485, rs2134623717, rs2135518426, rs2135517612, rs200709238, rs371565413, rs899592055, rs367981116, rs780695088, rs777654507, rs376778056, rs376392495, rs759084475, rs115353159, rs2497601690, rs1401698190, rs1451432673, rs1948389710, rs201734237, rs776794801, rs2497598968, rs1341434202, rs144248214, rs200761835, rs201373014, rs752526094, rs776171575, rs923539173, rs1444968086, rs1948406975, rs1565465474, rs2497598816, rs2497612146, rs2497600913, rs1085307094, rs878854712, rs878854711, rs776350272, rs760543488, rs764221630, rs2497601597, rs8192613, rs774317271, rs201685069, rs2497598956, rs2497600885, rs2497600776, rs769554839, rs770181064, rs2497599283, rs1193036142, rs1948468170, rs1003781488, rs2497600863, rs2497601663, rs2497612160, rs756573538, rs1248646475, rs1948402705, rs758825110, rs2497600596, rs1346537909, rs201460753, rs751437266, rs760669515, rs201971719, rs17121818, rs1064796044, rs754755062, rs200842493, rs767589740, rs780138122, rs376823705, rs777479532, rs149169244, rs533110688, rs150955748, rs72544143, rs369196654, rs753389706, rs767173208, rs140034265, rs760333798, rs961380475, rs772656576, rs17121819, rs72544145, rs587777023, rs72544144, rs1948388818, rs200264107, rs774866184, rs767512158, rs1948405888, rs765743471	RCV001323366 RCV001322683 RCV001368324 RCV001418368 RCV001404706 RCV001395921 RCV001457541 RCV001455208 RCV001479121 RCV001480979 RCV001495226 RCV001512543 RCV001978689 RCV001917792 RCV001936821 RCV001945378 RCV002019463 RCV001920085 RCV001877205 RCV001925853 RCV001946015 RCV001901416 RCV001880942 RCV002048261 RCV001985103 RCV002024898 RCV002102343 RCV002169827 RCV002075228 RCV002169071 RCV002105843 RCV002185845 RCV002116231 RCV002121191 RCV002145914 RCV002203296 RCV002147644 RCV002090993 RCV003099446 RCV003741298 RCV003096724 RCV003581837 RCV003741306 RCV003138201 RCV003096871 RCV003774202 RCV003774401 RCV003102109 RCV003071317 RCV003081285 RCV003079397 RCV003078255 RCV003072911 RCV001043282 RCV001220499 RCV001335157 RCV002637531 RCV002587677 RCV002589987 RCV002626334 RCV002889515 RCV002909248 RCV003049524 RCV003040939 RCV003065952 RCV000490510 RCV000232198 RCV000228357 RCV003136441 RCV003136442 RCV003741334 RCV003224730 RCV001807167 RCV001854995 RCV003582467 RCV003581520 RCV003582764 RCV003582963 RCV003741422 RCV003741602 RCV003741913 RCV003742055 RCV003741971 RCV003742143 RCV003742145 RCV003742443 RCV003742456 RCV003742415 RCV003742585 RCV003740852 RCV003876908 RCV003882713 RCV005100491 RCV000456620 RCV000465102 RCV001488346 RCV000472431 RCV001476326 RCV000464872 RCV000458076 RCV001206528 RCV000559334 RCV000544526 RCV000655070 RCV002065211 RCV002529478 RCV002531655 RCV002063879 RCV000867780 RCV002063933 RCV000866035 RCV001803880 RCV001860373 RCV000655069 RCV000688074 RCV000811103 RCV001869261 RCV000868224 RCV001417399 RCV001404574 RCV000054539 RCV000054540 RCV000824359 RCV001458307 RCV001041156 RCV001218141 RCV001204333 RCV001228870 RCV001248262 RCV001303174
Cardiovascular phenotype	Uncertain significance; Likely benign; Benign; Conflicting classifications of pathogenicity	rs1948399832, rs142643516, rs771234231, rs371409245, rs1217452578, rs752863331, rs981151593, rs376336851, rs369244943, rs765701955, rs552421963, rs772817742, rs758238682, rs1024654954, rs1192595114, rs776528668, rs140314864, rs757644485, rs2135518426, rs367981116, rs2497612420, rs763298135, rs370514575, rs1357179437, rs1170933230, rs752036741, rs1591447468, rs371375392, rs780695088, rs2497598930, rs1243940123, rs1485320329, rs765743471, rs758440956, rs777654507, rs1214055007, rs376778056, rs376392495, rs1291362198, rs1052467646, rs1187711592, rs759084475, rs1948388978, rs115353159, rs926157678, rs1043620518, rs2497601690, rs1401698190, rs777194638, rs1451432673, rs760016611, rs144248214, rs200761835, rs201373014, rs776171575, rs1444968086, rs1555100654, rs1240316703, rs878854712, rs2497598759, rs2497598743, rs2497600958, rs1948402186, rs761673618, rs762546637, rs764221630, rs2497601597, rs774317271, rs2497598814, rs17121819, rs2497600863, rs1411707172, rs1948389268, rs2497598956, rs2497600596, rs2497600902, rs1346537909, rs1299303400, rs2497600716, rs1948400468, rs376823705, rs201460753, rs751437266, rs760669515, rs201971719, rs17121818, rs1064796044, rs868793059, rs200709238, rs767589740, rs780138122, rs777479532, rs149169244, rs533110688, rs150955748, rs369196654, rs753389706, rs140034265, rs760333798, rs961380475, rs772656576, rs72544145, rs587777023, rs72544144, rs200264107, rs774866184	RCV004035099 RCV002456443 RCV002438858 RCV004038156 RCV002341845 RCV005480744 RCV005271312 RCV002449307 RCV003298915 RCV002334942 RCV005722562 RCV002440951 RCV003167300 RCV004041118 RCV005266114 RCV004982877 RCV004046293 RCV004982932 RCV002391303 RCV002451902 RCV002337538 RCV002348883 RCV002321271 RCV002321370 RCV002333490 RCV002455318 RCV002355162 RCV002332243 RCV002324953 RCV002349841 RCV002359632 RCV002357875 RCV002357961 RCV002344182 RCV002347256 RCV002356130 RCV002342196 RCV002342293 RCV002351457 RCV002361830 RCV002351607 RCV002351927 RCV002351928 RCV002351964 RCV002359749 RCV002380512 RCV002380010 RCV002376634 RCV002398599 RCV002383672 RCV002437332 RCV002441686 RCV002354429 RCV002336406 RCV002326940 RCV005724803 RCV004656946 RCV004135627 RCV004124454 RCV002321873 RCV003165295 RCV003176502 RCV003176503 RCV003176504 RCV003165296 RCV003216331 RCV003216332 RCV005725007 RCV000249593 RCV003296606 RCV003296607 RCV003296608 RCV003377701 RCV003377702 RCV003377703 RCV005273737 RCV004985496 RCV004987136 RCV004454902 RCV004519056 RCV004519057 RCV004519058 RCV004519059 RCV004519060 RCV005732106 RCV002429508 RCV004022958 RCV002436428 RCV002356739 RCV002393126 RCV002356678 RCV002367650 RCV004659071 RCV002334001 RCV000620580 RCV002325148 RCV002334007 RCV002341573 RCV002456366 RCV002384339 RCV002384322 RCV000619382 RCV003163021 RCV002352410 RCV002434034 RCV002336797 RCV002332810 RCV004659248 RCV002426610 RCV004018968 RCV002354244 RCV002454167 RCV002365987 RCV002436786 RCV005271130
Ovarian serous cystadenocarcinoma	Benign	rs648389	RCV005904121
Primary dilated cardiomyopathy	Uncertain significance	rs868793059	RCV000498414
SCN2B-related disorder	Benign; Likely benign; Uncertain significance	rs140314864, rs370514575, rs376392495	RCV003984195 RCV003395458 RCV003961005
Variant of unknown significance	Uncertain significance	rs587777023	RCV000054543

Associations from Text Mining
Disease Name	Relationship Type	References
Atrial Fibrillation	Associate	20558140, 30821358, 34332113
Brugada Syndrome	Associate	26173111
Cardiomyopathy Dilated	Associate	24339868
Cognitive Dysfunction	Associate	36406589
Encephalitis Viral	Associate	37891420
Inflammation	Associate	37891420