SAA2 (serum amyloid A2)

Gene

• Entrez ID: 6289
• Gene name: Serum amyloid A2
• Gene symbol: SAA2
• Synonyms (NCBI Gene): SAA, SAA1
• Chromosome: 11
• Chromosome location: 11p15.1
• Summary: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflamm

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1324574	hsa-miR-1237	CLIP-seq
MIRT1324575	hsa-miR-1238	CLIP-seq
MIRT1324576	hsa-miR-1248	CLIP-seq
MIRT1324577	hsa-miR-1299	CLIP-seq
MIRT1324578	hsa-miR-136	CLIP-seq
MIRT1324579	hsa-miR-4270	CLIP-seq
MIRT1324580	hsa-miR-4320	CLIP-seq
MIRT1324581	hsa-miR-4441	CLIP-seq
MIRT1324582	hsa-miR-4490	CLIP-seq
MIRT1324583	hsa-miR-4691-5p	CLIP-seq
MIRT1324584	hsa-miR-4774-5p	CLIP-seq
MIRT1324585	hsa-miR-4782-5p	CLIP-seq
MIRT1324586	hsa-miR-4795-3p	CLIP-seq
MIRT1324587	hsa-miR-501-3p	CLIP-seq
MIRT1324588	hsa-miR-502-3p	CLIP-seq
MIRT1324589	hsa-miR-516b	CLIP-seq
MIRT1324590	hsa-miR-656	CLIP-seq
MIRT1324591	hsa-miR-875-3p	CLIP-seq
MIRT2096383	hsa-miR-326	CLIP-seq
MIRT2096384	hsa-miR-330-5p	CLIP-seq
MIRT2096385	hsa-miR-3684	CLIP-seq
MIRT2096386	hsa-miR-376c	CLIP-seq
MIRT2096387	hsa-miR-378	CLIP-seq
MIRT2096388	hsa-miR-378b	CLIP-seq
MIRT2096389	hsa-miR-378c	CLIP-seq
MIRT2096390	hsa-miR-378d	CLIP-seq
MIRT2096391	hsa-miR-378e	CLIP-seq
MIRT2096392	hsa-miR-378f	CLIP-seq
MIRT2096393	hsa-miR-378h	CLIP-seq
MIRT2096394	hsa-miR-378i	CLIP-seq
MIRT2096395	hsa-miR-422a	CLIP-seq
MIRT2096396	hsa-miR-4638-3p	CLIP-seq
MIRT2096397	hsa-miR-942	CLIP-seq
MIRT1324578	hsa-miR-136	CLIP-seq
MIRT2320570	hsa-miR-3115	CLIP-seq
MIRT2320571	hsa-miR-3121-5p	CLIP-seq
MIRT2320572	hsa-miR-3145-3p	CLIP-seq
MIRT2320573	hsa-miR-3152-3p	CLIP-seq
MIRT2320574	hsa-miR-362-5p	CLIP-seq
MIRT2320575	hsa-miR-3675-5p	CLIP-seq
MIRT2320576	hsa-miR-410	CLIP-seq
MIRT2320577	hsa-miR-4729	CLIP-seq
MIRT2320578	hsa-miR-500b	CLIP-seq
MIRT2320579	hsa-miR-501-5p	CLIP-seq
MIRT2320580	hsa-miR-599	CLIP-seq
MIRT2320581	hsa-miR-944	CLIP-seq
MIRT2394002	hsa-miR-4307	CLIP-seq
MIRT2394003	hsa-miR-567	CLIP-seq
MIRT1324582	hsa-miR-4490	CLIP-seq
MIRT1324584	hsa-miR-4774-5p	CLIP-seq
MIRT2616587	hsa-miR-140-5p	CLIP-seq
MIRT2616588	hsa-miR-323-5p	CLIP-seq
MIRT2616589	hsa-miR-3545-5p	CLIP-seq
MIRT2616590	hsa-miR-4460	CLIP-seq
MIRT2616591	hsa-miR-4727-3p	CLIP-seq
MIRT2616592	hsa-miR-876-3p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
CEBPB	Activation	8244997
RELA	Activation	8244997

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA
GO:0006953	Process	Acute-phase response	IEA
GO:0034364	Component	High-density lipoprotein particle	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145

Other IDs

• MIM: 104751
• HGNC: 10514
• e!Ensembl: ENSG00000134339

Protein

• UniProt ID: P0DJI9
• Protein name: Serum amyloid A-2 protein (SAA2) [Cleaved into: Amyloid A2 protein (AA2)]
• Protein function: Major acute phase reactant.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00277	SAA	22 → 122	Serum amyloid A protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed by the liver; secreted in plasma. {ECO:0000269|PubMed:3183061}.
• Sequence:

  MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNY
  DAAKRGPGGAWAAEVISNARENIQRLTGRGAEDSLADQAANKWGRSGRDPNHFRPAGLPE
  KY

• Sequence length: 122