S100A11 (S100 calcium binding protein A11)

Gene

• Entrez ID: 6282
• Gene name: S100 calcium binding protein A11
• Gene symbol: S100A11
• Synonyms (NCBI Gene): HEL-S-43, MLN70, S100C
• Chromosome: 1
• Chromosome location: 1q21.3
• Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of ce

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020889	hsa-miR-155-5p	Proteomics	18668040
MIRT023889	hsa-miR-1-3p	Proteomics	18668040
MIRT460531	hsa-miR-548az-5p	HITS-CLIP	23706177
MIRT460530	hsa-miR-548t-5p	HITS-CLIP	23706177
MIRT460529	hsa-miR-3609	HITS-CLIP	23706177
MIRT460528	hsa-miR-548ah-5p	HITS-CLIP	23706177
MIRT460527	hsa-miR-4307	HITS-CLIP	23706177
MIRT460526	hsa-miR-556-3p	HITS-CLIP	23706177
MIRT460525	hsa-miR-6516-3p	HITS-CLIP	23706177
MIRT500058	hsa-miR-648	PAR-CLIP	24398324
MIRT500057	hsa-miR-7854-3p	PAR-CLIP	24398324
MIRT500056	hsa-miR-6134	PAR-CLIP	24398324
MIRT500055	hsa-miR-6076	PAR-CLIP	24398324
MIRT500054	hsa-miR-6797-3p	PAR-CLIP	24398324
MIRT500053	hsa-miR-3934-3p	PAR-CLIP	24398324
MIRT500052	hsa-miR-876-3p	PAR-CLIP	24398324
MIRT500051	hsa-miR-142-3p	PAR-CLIP	24398324
MIRT500050	hsa-miR-3591-5p	PAR-CLIP	24398324
MIRT460531	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT460530	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT460529	hsa-miR-3609	PAR-CLIP	23592263
MIRT460528	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT460527	hsa-miR-4307	PAR-CLIP	23592263
MIRT460526	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT460525	hsa-miR-6516-3p	PAR-CLIP	23592263
MIRT439718	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439718	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT500051	hsa-miR-142-3p	PAR-CLIP	27292025
MIRT500050	hsa-miR-3591-5p	PAR-CLIP	27292025
MIRT460529	hsa-miR-3609	PAR-CLIP	27292025
MIRT500053	hsa-miR-3934-3p	PAR-CLIP	27292025
MIRT460527	hsa-miR-4307	PAR-CLIP	27292025
MIRT460528	hsa-miR-548ah-5p	PAR-CLIP	27292025
MIRT460531	hsa-miR-548az-5p	PAR-CLIP	27292025
MIRT460530	hsa-miR-548t-5p	PAR-CLIP	27292025
MIRT460526	hsa-miR-556-3p	PAR-CLIP	27292025
MIRT500055	hsa-miR-6076	PAR-CLIP	27292025
MIRT500056	hsa-miR-6134	PAR-CLIP	27292025
MIRT500058	hsa-miR-648	PAR-CLIP	27292025
MIRT460525	hsa-miR-6516-3p	PAR-CLIP	27292025
MIRT500054	hsa-miR-6797-3p	PAR-CLIP	27292025
MIRT500057	hsa-miR-7854-3p	PAR-CLIP	27292025
MIRT500052	hsa-miR-876-3p	PAR-CLIP	27292025
MIRT460531	hsa-miR-548az-5p	HITS-CLIP	23706177
MIRT460530	hsa-miR-548t-5p	HITS-CLIP	23706177
MIRT460529	hsa-miR-3609	HITS-CLIP	23706177
MIRT460528	hsa-miR-548ah-5p	HITS-CLIP	23706177
MIRT460527	hsa-miR-4307	HITS-CLIP	23706177
MIRT460526	hsa-miR-556-3p	HITS-CLIP	23706177
MIRT460525	hsa-miR-6516-3p	HITS-CLIP	23706177
MIRT500058	hsa-miR-648	PAR-CLIP	24398324
MIRT500057	hsa-miR-7854-3p	PAR-CLIP	24398324
MIRT500056	hsa-miR-6134	PAR-CLIP	24398324
MIRT500055	hsa-miR-6076	PAR-CLIP	24398324
MIRT500054	hsa-miR-6797-3p	PAR-CLIP	24398324
MIRT500053	hsa-miR-3934-3p	PAR-CLIP	24398324
MIRT500052	hsa-miR-876-3p	PAR-CLIP	24398324
MIRT500051	hsa-miR-142-3p	PAR-CLIP	24398324
MIRT500050	hsa-miR-3591-5p	PAR-CLIP	24398324
MIRT460531	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT460530	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT460529	hsa-miR-3609	PAR-CLIP	23592263
MIRT460528	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT460527	hsa-miR-4307	PAR-CLIP	23592263
MIRT460526	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT460525	hsa-miR-6516-3p	PAR-CLIP	23592263
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323863	hsa-miR-3918	CLIP-seq
MIRT1323864	hsa-miR-3936	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323869	hsa-miR-4493	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323877	hsa-miR-4685-5p	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323879	hsa-miR-4753-5p	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323882	hsa-miR-548ah	CLIP-seq
MIRT1323883	hsa-miR-548t	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323885	hsa-miR-615-5p	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323863	hsa-miR-3918	CLIP-seq
MIRT1323864	hsa-miR-3936	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323869	hsa-miR-4493	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323877	hsa-miR-4685-5p	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323879	hsa-miR-4753-5p	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323882	hsa-miR-548ah	CLIP-seq
MIRT1323883	hsa-miR-548t	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323863	hsa-miR-3918	CLIP-seq
MIRT1323864	hsa-miR-3936	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323869	hsa-miR-4493	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323877	hsa-miR-4685-5p	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323879	hsa-miR-4753-5p	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323882	hsa-miR-548ah	CLIP-seq
MIRT1323883	hsa-miR-548t	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323863	hsa-miR-3918	CLIP-seq
MIRT1323864	hsa-miR-3936	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323869	hsa-miR-4493	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323877	hsa-miR-4685-5p	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323879	hsa-miR-4753-5p	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323885	hsa-miR-615-5p	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq
MIRT1323852	hsa-miR-1252	CLIP-seq
MIRT1323853	hsa-miR-1266	CLIP-seq
MIRT1323854	hsa-miR-1270	CLIP-seq
MIRT1323855	hsa-miR-1272	CLIP-seq
MIRT1323856	hsa-miR-1293	CLIP-seq
MIRT1323857	hsa-miR-143	CLIP-seq
MIRT1323858	hsa-miR-1587	CLIP-seq
MIRT1323859	hsa-miR-2861	CLIP-seq
MIRT1323860	hsa-miR-3151	CLIP-seq
MIRT1323861	hsa-miR-3202	CLIP-seq
MIRT1323862	hsa-miR-3652	CLIP-seq
MIRT1323863	hsa-miR-3918	CLIP-seq
MIRT1323864	hsa-miR-3936	CLIP-seq
MIRT1323865	hsa-miR-4417	CLIP-seq
MIRT1323866	hsa-miR-4430	CLIP-seq
MIRT1323867	hsa-miR-4483	CLIP-seq
MIRT1323868	hsa-miR-4492	CLIP-seq
MIRT1323869	hsa-miR-4493	CLIP-seq
MIRT1323870	hsa-miR-4498	CLIP-seq
MIRT1323871	hsa-miR-4518	CLIP-seq
MIRT1323872	hsa-miR-4533	CLIP-seq
MIRT1323873	hsa-miR-4651	CLIP-seq
MIRT1323874	hsa-miR-4656	CLIP-seq
MIRT1323875	hsa-miR-4675	CLIP-seq
MIRT1323876	hsa-miR-4683	CLIP-seq
MIRT1323877	hsa-miR-4685-5p	CLIP-seq
MIRT1323878	hsa-miR-4741	CLIP-seq
MIRT1323879	hsa-miR-4753-5p	CLIP-seq
MIRT1323880	hsa-miR-4770	CLIP-seq
MIRT1323881	hsa-miR-541	CLIP-seq
MIRT1323884	hsa-miR-608	CLIP-seq
MIRT1323885	hsa-miR-615-5p	CLIP-seq
MIRT1323886	hsa-miR-620	CLIP-seq
MIRT1323887	hsa-miR-629	CLIP-seq
MIRT1323888	hsa-miR-654-5p	CLIP-seq
MIRT1323889	hsa-miR-762	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
STAT3	Activation	24376686

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001726	Component	Ruffle	IDA	10913138
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	10913138, 31837246, 32296183, 36555597
GO:0005576	Component	Extracellular region	HDA	27068509
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	16502470, 23580065
GO:0005634	Component	Nucleus	IDA	10913138
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	10851017
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	10913138
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	10851017, 16130169
GO:0005912	Component	Adherens junction	HDA	25468996
GO:0007165	Process	Signal transduction	TAS	16130169
GO:0008156	Process	Negative regulation of DNA replication	TAS	10851017
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	10851017
GO:0014911	Process	Positive regulation of smooth muscle cell migration	IMP	21139050
GO:0034774	Component	Secretory granule lumen	TAS
GO:0042127	Process	Regulation of cell population proliferation	IEA
GO:0042803	Function	Protein homodimerization activity	IDA	10913138
GO:0044548	Function	S100 protein binding	IBA
GO:0044548	Function	S100 protein binding	IPI	10913138
GO:0046872	Function	Metal ion binding	IEA
GO:0048306	Function	Calcium-dependent protein binding	IBA
GO:0048306	Function	Calcium-dependent protein binding	IDA	10913138
GO:0048306	Function	Calcium-dependent protein binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19199708, 23533145
GO:0098609	Process	Cell-cell adhesion	IEA
GO:0098641	Function	Cadherin binding involved in cell-cell adhesion	HDA	25468996

Other IDs

• MIM: 603114
• HGNC: 10488
• e!Ensembl: ENSG00000163191

Protein

• UniProt ID: P31949
• Protein name: Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed]
• Protein function: Facilitates the differentiation and the cornification of keratinocytes.
• PDB: 1V4Z, 1V50, 2LUC
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01023	S_100	10 → 52	S-100/ICaBP type calcium binding domain	Domain
  PF00036	EF-hand_1	59 → 87	EF hand	Domain

• Sequence:

  MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL
  DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT

• Sequence length: 105

Pathways

Reactome:

Neutrophil degranulation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenocarcinoma	Stimulate	26544866	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of Lung	Associate	26544866	★☆☆☆☆ Found in Text Mining only
Adenomatous Polyposis Coli	Associate	33466593	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Associate	28446208, 33727634, 36614150	★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Associate	33727634	★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Associate	25487697	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Stimulate	21153724	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	28051137, 38129538	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	24376686, 33546025, 37166978	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	17537172, 25940438	★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Stimulate	33763485	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Associate	31046874	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Stimulate	35752610	★☆☆☆☆ Found in Text Mining only
Carcinoma Papillary Follicular	Associate	25880590	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Associate	21897749	★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Stimulate	29569474	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	33294444, 34080639, 37879212	★☆☆☆☆ Found in Text Mining only
Dermatitis Atopic	Inhibit	18385759	★☆☆☆☆ Found in Text Mining only
Endocarditis	Stimulate	22319637	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Associate	35682908	★☆☆☆☆ Found in Text Mining only
Fibrosis	Associate	34663163	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Associate	32510239, 39684695	★☆☆☆☆ Found in Text Mining only
Glioma	Associate	37864150	★☆☆☆☆ Found in Text Mining only
Graves Ophthalmopathy	Associate	37059863	★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	22990588, 28446208, 34653793	★☆☆☆☆ Found in Text Mining only
Inflammation	Stimulate	33727634	★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Associate	36643579	★☆☆☆☆ Found in Text Mining only
Laryngeal Neoplasms	Stimulate	24046531	★☆☆☆☆ Found in Text Mining only
Lymphoma Large Cell Anaplastic	Associate	16351635	★☆☆☆☆ Found in Text Mining only
Lymphoma Non Hodgkin	Associate	34148033	★☆☆☆☆ Found in Text Mining only
Melanoma	Associate	30216200, 37356089	★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Associate	25007175	★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Associate	34653793	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Stimulate	17537172, 38341855	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	33763485, 35752610	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	11873942	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	17537172, 17978094, 24475253, 25565331, 26544866, 28446208, 28701735, 31046874, 33763485, 34563043, 35752610, 38129538, 9920419	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	24806074, 25007175	★☆☆☆☆ Found in Text Mining only
Neoplasms Squamous Cell	Stimulate	17978094	★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Associate	24905701, 28446208	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Associate	38341855	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Stimulate	33217795	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	31046874, 33580614, 35752610	★☆☆☆☆ Found in Text Mining only
Pterygium	Associate	19223989	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Associate	25487697	★☆☆☆☆ Found in Text Mining only
Sick Sinus Syndrome	Stimulate	17537172	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	24046531	★☆☆☆☆ Found in Text Mining only
Staphylococcal Infections	Stimulate	22319637	★☆☆☆☆ Found in Text Mining only
Streptococcal Infections	Stimulate	22319637	★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Stimulate	25880590	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Associate	26508026	★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Associate	9920419	★☆☆☆☆ Found in Text Mining only
Venous Malformations Multiple Cutaneous and Mucosal	Associate	37927791	★☆☆☆☆ Found in Text Mining only