RYR3 (ryanodine receptor 3)

Gene

• Entrez ID: 6263
• Gene name: Ryanodine receptor 3
• Gene symbol: RYR3
• Synonyms (NCBI Gene): CMYO20, CMYP20, RYR-3
• Chromosome: 15
• Chromosome location: 15q13.3-q14
• Summary: The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium fr

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022517	hsa-miR-124-3p	Microarray	18668037
MIRT029294	hsa-miR-26b-5p	Microarray	19088304
MIRT739901	hsa-miR-3667-3p	HITS-CLIP	33718276
MIRT739902	hsa-miR-4297	HITS-CLIP	33718276
MIRT739900	hsa-miR-1237	CLIP-seq
MIRT739899	hsa-miR-1248	CLIP-seq
MIRT1323794	hsa-miR-1297	CLIP-seq
MIRT1323795	hsa-miR-181a	CLIP-seq
MIRT1323796	hsa-miR-181b	CLIP-seq
MIRT1323797	hsa-miR-181c	CLIP-seq
MIRT1323798	hsa-miR-181d	CLIP-seq
MIRT1323799	hsa-miR-26a	CLIP-seq
MIRT1323800	hsa-miR-26b	CLIP-seq
MIRT1323801	hsa-miR-4262	CLIP-seq
MIRT1323802	hsa-miR-4465	CLIP-seq
MIRT739898	hsa-miR-4778-3p	CLIP-seq
MIRT1323803	hsa-miR-513a-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005216	Function	Monoatomic ion channel activity	IEA
GO:0005219	Function	Ryanodine-sensitive calcium-release channel activity	IBA
GO:0005219	Function	Ryanodine-sensitive calcium-release channel activity	IEA
GO:0005219	Function	Ryanodine-sensitive calcium-release channel activity	ISS
GO:0005219	Function	Ryanodine-sensitive calcium-release channel activity	TAS	19095005
GO:0005262	Function	Calcium channel activity	IEA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005516	Function	Calmodulin binding	IEA
GO:0005790	Component	Smooth endoplasmic reticulum	IBA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0006816	Process	Calcium ion transport	IMP	9395096
GO:0006874	Process	Intracellular calcium ion homeostasis	IEA
GO:0006941	Process	Striated muscle contraction	IBA
GO:0014808	Process	Release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	IBA
GO:0015278	Function	Intracellularly gated calcium channel activity	IEA
GO:0015278	Function	Intracellularly gated calcium channel activity	IMP	9395096
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016529	Component	Sarcoplasmic reticulum	IEA
GO:0019722	Process	Calcium-mediated signaling	IEA
GO:0030018	Component	Z disc	IBA
GO:0033017	Component	Sarcoplasmic reticulum membrane	IBA
GO:0033017	Component	Sarcoplasmic reticulum membrane	IEA
GO:0033017	Component	Sarcoplasmic reticulum membrane	ISS
GO:0033017	Component	Sarcoplasmic reticulum membrane	ISS
GO:0033017	Component	Sarcoplasmic reticulum membrane	TAS
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034704	Component	Calcium channel complex	IBA
GO:0042383	Component	Sarcolemma	IBA
GO:0048763	Function	Calcium-induced calcium release activity	ISS
GO:0051209	Process	Release of sequestered calcium ion into cytosol	ISS
GO:0051289	Process	Protein homotetramerization	ISS
GO:0055085	Process	Transmembrane transport	IEA
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0070588	Process	Calcium ion transmembrane transport	ISS
GO:0071277	Process	Cellular response to calcium ion	ISS
GO:0071286	Process	Cellular response to magnesium ion	ISS
GO:0071313	Process	Cellular response to caffeine	ISS
GO:0071318	Process	Cellular response to ATP	ISS

Other IDs

• MIM: 180903
• HGNC: 10485
• e!Ensembl: ENSG00000198838

Protein

• UniProt ID: Q15413
• Protein name: Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
• Protein function: Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction (PubMed:12354756, PubMed:9395096). May regulat
• PDB: 4ERV, 6UHA, 6UHB, 6UHE, 6UHH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08709	Ins145_P3_rec	10 → 212	Inositol 1,4,5-trisphosphate/ryanodine receptor	Domain
  PF02815	MIR	216 → 398	MIR domain	Domain
  PF01365	RYDR_ITPR	440 → 635	RIH domain	Family
  PF00622	SPRY	659 → 794	SPRY domain	Family
  PF02026	RyR	849 → 939	RyR domain	Family
  PF02026	RyR	963 → 1053	RyR domain	Family
  PF00622	SPRY	1086 → 1206	SPRY domain	Family
  PF00622	SPRY	1327 → 1463	SPRY domain	Family
  PF01365	RYDR_ITPR	2021 → 2233	RIH domain	Family
  PF02026	RyR	2598 → 2688	RyR domain	Family
  PF02026	RyR	2716 → 2800	RyR domain	Family
  PF08454	RIH_assoc	3726 → 3844	RyR and IP3R Homology associated	Family
  PF06459	RR_TM4-6	4234 → 4504	Ryanodine Receptor TM 4-6	Family
  PF00520	Ion_trans	4605 → 4781	Ion transport protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Brain, skeletal muscle, placenta and possibly liver and kidney. In brain, highest levels are found in the cerebellum, hippocampus, caudate nucleus and amygdala, with lower levels in the corpus callosum, substantia nigra and thalamus. {
• Sequence:

  MAEGGEGGEDEIQFLRTEDEVVLQCIATIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIP
  PDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAVLLRHSFSGMYL
  TCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER
  YLHLSVSNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTD
  QNDSQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTED
  QGLILQDRAKSDTKSTAFSFRASKELKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIAS
  GLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQ
  FVSGNNRTAAPITLPIEEVLQTLQDLIAYFQPPEEEMRHEDKQNKLRSLKNRQNLFKEEG
  MLALVLNCIDRLNVYNSVAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSN
  NLDWLISKLDRLESSSGILEVLHCILTESPEALNLIAEGHIKSIISLLDKHGRNHKVLDI
  LCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW
  YFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW
  SGRIPRAVASINQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVMS
  FSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDADGIRDLLGT
  TQFLSQASFIPCPVDTSQVILPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKR
  QHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLPKNYMMS
  NGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV
  PYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADSAVEKVSIDKIRFFRVERSY
  AVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGNRGQRWHQGSGYFGR
  TWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICCLGLSQIGR
  MNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVMRID
  GTMDSPPCLKVTHKTFGTQNSNADMIYCRLSMPVECHSSFSHSPCLDSEAFQKRKQMQEI
  LSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHE
  SVKRSNCYMVWGGDIVASSQRSNRSNVDLEIGCLVDLAMGMLSFSANGKELGTCYQVEPN
  TKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFRSEEKNPVPQCPPRLDVQTIQPVLW
  SRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYH
  TLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKE
  RKLMMKNEYIIPITSTTRNIRLFPDESKRHGLPGVGLRTCLKPGFRFSTPCFVVTGEDHQ
  KQSPEIPLESLRTKALSMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDD
  DDVRQILLLIDPSVFGEHSAGTEEGAEKEEVTQVEEKAVEAGEKAGKEAPVKGLLQTRLP
  ESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTA
  RKTKEFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEED
  TSWTGKLCALVYKIKGPPKPEKEQPTEEEERCPTTLKELISQTMICWAQEDQIQDSELVR
  MMFNLLRRQYDSIGELLQALRKTYTISHTSVSDTINLLAALGQIRSLLSVRMGKEEELLM
  INGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGTEKSQIAFPKMVASCCRFLCYF
  CRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALSLEEPDLE
  KVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKL
  LIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVSTGDDEEEEEIVH
  MGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLP
  SLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLD
  TVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHCTSLIDSTLQTIYRLSKGRSLTK
  AQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCL
  PSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDT
  RITATLEKQISVDADGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDKSQSGWKY
  GISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGEALVQQRE
  NEKLRSVSQANQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGG
  GSHPLLVPYDTLTAKEKFKDREKAQDLFKFLQVNGIIVSRGMKDMELDASSMEKRFAYKF
  LKKILKYVDSAQEFIAHLEAIVSSGKTEKSPRDQEIKFFAKVLLPLVDQYFTSHCLYFLS
  SPLKPLSSSGYASHKEKEMVAGLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRT
  VMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPI
  LTSIFEHVTQHQFGMDLLLGDVQISCYHILCSLYSLGTGKNIYVERQRPALGECLASLAA
  AIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEDMCPDIPQLEGLMKEINDLAES
  GARYTEMPHVIEVILPMLCNYLSYWWERGPENLPPSTGPCCTKVTSEHLSLILGNILKII
  NNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLKADG
  KGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEVFI
  LWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKKTKRRGDLY
  SIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSHRDTDEEVREHLRNNLHLQEKS
  DDPAVKWQLNLYKDVLKSEEPFNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLS
  KQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEE
  EEEEETEKQPDPLHQIILYFSRNALTERSKLEDDPLYTSYSSMMAKSCQSGEDEEEDEDK
  EKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGN
  AGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRE
  RGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQES
  ISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAV
  VGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLV
  ESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEID
  FLLSCAEADENDMFNYVDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAES
  VLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQE
  KMELFVNFCEDTIFEMQLASQISESDSADRPEEEEEDEDSSYVLEIAGEEEEDGSLEPAS
  AFAMACASVKRNVTDFLKRATLKNLRKQYRNVKKMTAKELVKVLFSFFWMLFVGLFQLLF
  TILGGIFQILWSTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDTMEAERAEVMEPGI
  TTELVHFIKGEKGDTDIMSDLFGLHPKKEGSLKHGPEVGLGDLSEIIGKDEPPTLESTVQ
  KKRKAQAAEMKAANEAEGKVESEKADMEDGEKEDKDKEEEQAEYLWTEVTKKKKRRCGQK
  VEKPEAFTANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEE
  ETEDVANLWNSFNDEEEEEAMVFFVLQESTGYMAPTLRALAIIHTIISLVCVVGYYCLKV
  PLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVIN
  KYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHIWKLGVVFTDN
  SFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVV
  VYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGD
  PYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDY
  FDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDC
  FRKQYEDQLG

• Sequence length: 4870

Pathways

KEGG:

Calcium signaling pathway
Apelin signaling pathway
Circadian entrainment
Oxytocin signaling pathway
Salivary secretion
Alzheimer disease
Parkinson disease
Prion disease
Pathways of neurodegeneration - multiple diseases

Reactome:

Stimuli-sensing channels
Ion homeostasis

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Hydrops fetalis	Pathogenic	rs2152767575	RCV001842232

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Benign	rs117754976	RCV005928260
Arthrogryposis multiplex congenita	Uncertain significance	rs1466702657	RCV000855509
Cervical cancer	Benign	rs117754976, rs79305633	RCV005928262 RCV005901383
Colon adenocarcinoma	Benign	rs80354707, rs79305633	RCV005901389 RCV005901380
Colorectal cancer	Benign	rs11853872	RCV005914326
Congenital myopathy 20	Uncertain significance; Conflicting classifications of pathogenicity	rs372207437, rs752713454, rs924245334, rs765319074, rs2504528536, rs374580756, rs1380669369, rs199648816, rs769938343, rs41279210, rs202140253, rs942287498, rs200346049, rs549279246, rs1314283337, rs375998723, rs1294722820, rs776691651, rs201310633	RCV003761205 RCV005860344 RCV003493150 RCV003493151 RCV003764492 RCV003990545 RCV003990546 RCV005409669 RCV003162847 RCV003492136 RCV003492134 RCV005012369 RCV003166301 RCV003166284 RCV003160165 RCV003492216 RCV005866858 RCV005409784 RCV004799638
Epileptic encephalopathy	Uncertain significance; Likely benign; Conflicting classifications of pathogenicity; Benign	rs373319826, rs761653150, rs1567552866, rs747346417, rs868245910, rs760906719, rs146818373, rs2059758473, rs1003058342, rs369597197, rs1272965489, rs2061507973, rs2062301446, rs2062301610, rs1596032965, rs373416062, rs200938517, rs749924697, rs1372401398, rs1566992285, rs760887545, rs1244617514, rs2070686005, rs776121340, rs2074308170, rs777925575, rs775224723, rs369695196, rs373622365, rs780080294, rs1214695856, rs1316205507, rs767795631, rs747918264, rs1186228421, rs982440028, rs114374205, rs775664813, rs2078205814, rs371107228, rs753219318, rs747821141, rs431825174, rs780128168, rs2056571810, rs1246698572, rs370829333, rs781281296, rs747174943, rs2060285743, rs2061252879, rs781225171, rs747990987, rs1566835895, rs201820155, rs2061501870, rs1373277946, rs2062109034, rs777615310, rs200404286, rs754438842, rs374176908, rs902077377, rs777398893, rs568206904, rs776190758, rs2068161998, rs372140871, rs1229836411, rs2069456146, rs905457147, rs1249446520, rs772748749, rs373117998, rs2074669089, rs199625290, rs781218159, rs2076654425, rs186218390, rs776872340, rs758369363, rs200724737, rs751533922, rs2078151869, rs772124153, rs377237772, rs1414118993, rs369559898, rs772160575, rs2078517547, rs1207059445, rs2079338485, rs1459857507, rs767355524, rs201612485, rs372207437, rs1395303451, rs2141046682, rs2141149139, rs1296124289, rs746548925, rs1353581080, rs760619857, rs1340198830, rs754472286, rs374941142, rs754600756, rs772157944, rs563422149, rs2152706232, rs2152706401, rs753308511, rs779248524, rs1596205665, rs116926961, rs1187202458, rs754370784, rs1306167957, rs770979189, rs745908297, rs527855635, rs772102927, rs1315782115, rs2152908209, rs762199883, rs368430766, rs1477239834, rs577747200, rs762478512, rs374083464, rs2152999058, rs750177909, rs1235991079, rs775657710, rs1188249908, rs947773003, rs2055756292, rs765304371, rs977071011, rs1456880473, rs1476873999, rs112038923, rs762956231, rs763470148, rs2152555558, rs764222669, rs2152689397, rs139771099, rs2063241843, rs1168377917, rs368923151, rs946067814, rs1200299363, rs745314071, rs2152784762, rs200619009, rs758576038, rs778988008, rs181380957, rs759021326, rs367760286, rs374767894, rs920966350, rs371642568, rs759672390, rs765557026, rs963892173, rs780189239, rs73372074, rs1312741458, rs2078190504, rs772448824, rs2152991544, rs748398395, rs1395244417, rs996769654, rs2153001337, rs2079850295, rs377333580, rs868842736, rs762392050, rs769694918, rs1391569161, rs773675905, rs749997491, rs1012795589, rs750035676, rs780290440, rs2058831483, rs2152645579, rs373214943, rs200884395, rs191714742, rs183464547, rs2152702882, rs115119086, rs771420569, rs2152720626, rs1213613702, rs2152723349, rs369092039, rs897706444, rs368153992, rs377655671, rs533168127, rs760254954, rs761169385, rs567995390, rs769796260, rs747055882, rs747567923, rs2152944244, rs370713645, rs1391585670, rs2077642739, rs1319476449, rs541616608, rs771819233, rs2078195511, rs759588731, rs1159495752, rs2152984948, rs369693970, rs367769357, rs1237804448, rs754520283, rs763714958, rs757023207, rs775464569, rs2153029627, rs781479912, rs375082087, rs1164929999, rs2056388979, rs186826524, rs577999387, rs1386758406, rs1421701855, rs935925259, rs370168429, rs2152628089, rs374544548, rs2152648478, rs1024822835, rs765954858, rs747806695, rs565115359, rs759769217, rs368964215, rs927858285, rs1172406378, rs2152771077, rs764201505, rs763965297, rs781639482, rs2070678544, rs1207690218, rs757734841, rs1227963148, rs376100096, rs896103641, rs947667794, rs2152888556, rs769276514, rs2152891268, rs777176325, rs772120545, rs904778183, rs2152913310, rs1299599534, rs1281867831, rs2152945282, rs150064528, rs180899760, rs1365718825, rs890576989, rs756140226, rs754018046, rs1596959088, rs748783723, rs200841538, rs1295538472, rs1323020118, rs780896166, rs752692253, rs199968653, rs371821413, rs897878116, rs1174654342, rs2058512031, rs762519563, rs201604156, rs1308305216, rs1259476488, rs370927090, rs760334224, rs565425018, rs2152646146, rs891617957, rs967779289, rs1220206850, rs372058994, rs2152706547, rs779006493, rs770898624, rs760634766, rs745504722, rs761834920, rs1263277256, rs773133967, rs954764673, rs763959882, rs377021941, rs748634579, rs745512396, rs781065862, rs773821075, rs751841256, rs757912975, rs201505340, rs556697081, rs1041677379, rs765948802, rs2076470416, rs1182854700, rs370943482, rs753759751, rs770461745, rs1231453709, rs576503078, rs2152988289, rs199505984, rs756633807, rs777630807, rs372037224, rs139758855, rs2153026492, rs370200639, rs1435100, rs539122445, rs11853872, rs674155, rs2077268, rs756530492, rs2229116, rs2229117, rs35706688, rs200901254, rs4780144, rs376874946, rs2293028, rs2293027, rs6495228, rs41279212, rs2288613, rs2288614, rs12914825, rs3217346, rs41279228, rs2303310, rs35254800, rs2152551537, rs750160431, rs756729023, rs200236669, rs1195837601, rs757712511, rs370732432, rs762093960, rs776257846, rs2152845782, rs559236938, rs2078190366, rs2070931192, rs774050928, rs775206941, rs1423109122, rs781202685, rs2152705984, rs2078134953, rs1424805766, rs2073620794, rs2152491034, rs781652433, rs779051107, rs2152832472, rs1188536603, rs2152971018, rs762804569, rs372700273, rs1309538160, rs368925275, rs1253604633, rs376267599, rs756969948, rs765516288, rs41279208, rs2437135, rs41279232, rs187683828, rs542705188, rs2152631552, rs199554108, rs8041960, rs2066763725, rs1260585204, rs374218298, rs960358144, rs1285776059, rs370439483, rs117754976, rs2288616, rs2288612, rs115679763, rs2152645918, rs747693615, rs3751634, rs2279662, rs374195884, rs75791977, rs148016052, rs374898131, rs371057517, rs540408111, rs2506463683, rs762176717, rs1156880664, rs765978043, rs1307336838, rs114471843, rs61749016, rs182323574, rs1555515067, rs758671481, rs2304380, rs146838868, rs202244063, rs74005691, rs570514213, rs201215774, rs2229118, rs2229119, rs199638420, rs368914456, rs753104655, rs370044621, rs542160399, rs1430659504, rs61996324, rs1217109352, rs375544562, rs1555397898, rs59021219, rs777812122, rs187374038, rs372003689, rs199648816, rs1485101035, rs74005974, rs1400678942, rs756348758, rs376062318, rs977035002, rs61996340, rs201961808, rs1555456725, rs55650127, rs182972491, rs61996336, rs192619532, rs183717988, rs200647737, rs369689229, rs10714306, rs138744371, rs75286462, rs372580668, rs760837521, rs775487863, rs1555488276, rs781372766, rs374667875, rs369078948, rs368370540, rs138901366, rs80182654, rs41279202, rs201830013, rs190742260, rs764823480, rs146892882, rs114825824, rs1555384709, rs183792071, rs908431118, rs553354987, rs1009308978, rs187371252, rs767314207, rs139287308, rs199928344, rs74005978, rs112521485, rs191980061, rs41279214, rs7165225, rs41279216, rs74437672, rs200133020, rs61996335, rs200304191, rs61996338, rs377437662, rs147149598, rs773752097, rs201375567, rs1555485015, rs115338509, rs201791791, rs201701548, rs113189230, rs374563732, rs2304386, rs368972337, rs16972317, rs1171648016, rs374709083, rs746285785, rs1264434931, rs747480589, rs199500216, rs75782410, rs202183681, rs182429820, rs752228470, rs750424423, rs746207106, rs774751337, rs78825800, rs115321092, rs200740143, rs148818748, rs377018905, rs527977093, rs201524472, rs80354707, rs113699058, rs202185923, rs61996329, rs775041835, rs115185294, rs766576655, rs181264765, rs771479235, rs1555429116, rs61996331, rs149242033, rs757395431, rs192820783, rs201561672, rs186614396, rs188257094, rs748002152, rs763876855, rs190035689, rs150799181, rs139568967, rs199745365, rs753270695, rs16958093, rs368231214, rs150028316, rs747519835, rs770778818, rs58745096, rs371629185, rs757214631, rs200401387, rs202181075, rs146201205, rs148918638, rs189410371, rs374756167, rs373615131, rs118177681, rs114681942, rs116123066, rs759709172, rs376071087, rs200281542, rs768358263, rs747633069, rs182257230, rs1374677399, rs374117753, rs79305633, rs199960256, rs780150644, rs368209451, rs1265752109, rs745955551, rs377602819, rs1555522270, rs1252434951, rs549685153, rs201161868, rs772565900, rs199507912, rs200944014, rs61996325, rs375210672, rs185038162, rs370232598, rs186300217, rs376084861, rs201633619, rs757827471, rs367645223, rs201031443, rs373358710, rs200111368, rs765011115, rs369629619, rs770219178, rs536504096, rs374221046, rs201746379, rs759749942, rs200309704, rs1415731316, rs118124507, rs141534340, rs371603240, rs111370716, rs770077165, rs762140107, rs10851894, rs1465461269, rs369156367, rs73383308, rs574626021, rs180882042, rs376097393, rs779158082, rs765872802, rs199931215, rs371008125, rs369140231, rs778575404, rs374921732, rs770836948, rs1337858544, rs142108245, rs1225273407, rs763416818, rs372479066, rs374959679, rs565033705, rs201051485, rs377360254, rs74005937, rs750872747, rs183255287, rs199615159, rs369574863, rs142550033, rs375286188, rs769938343, rs1278108928, rs201914506, rs1002586633, rs762655537, rs189282419, rs759031318, rs200830195, rs1299339478, rs765266347, rs562147027, rs538703172, rs8029260, rs903865101, rs751164469, rs1488578809, rs749732234, rs760643042, rs200346395, rs780109992, rs199645058, rs909959183, rs1162778289, rs189828361, rs372798643, rs377266014, rs746486931, rs765473326, rs760123258, rs1462237800, rs1555430248, rs1555433914, rs377292446, rs1555450889, rs192484612, rs575029619, rs367892350, rs201724283, rs201660041, rs770116543, rs1555493768, rs760373919, rs199553688, rs779658280, rs771903948, rs200724716, rs991186397, rs757011633, rs1567585393, rs776048938, rs942257120, rs575120914, rs368220434, rs762292478, rs537188316, rs114430766, rs200035756, rs201633381, rs1567143157, rs780806800, rs377341748, rs756934182, rs1567232258, rs751020610, rs139249269, rs770667248, rs377310965, rs972426377, rs780970109, rs766106079, rs370984175, rs1186954298, rs375458327, rs760270042, rs41279210, rs200294137, rs201516802, rs576237958, rs375015024, rs1481136779, rs774409645, rs774163504, rs138636427, rs140386682, rs1567354675, rs756571013, rs139577597, rs766700534, rs932569732, rs771092854, rs1566808408, rs774928735, rs1566832410, rs368769268, rs764730525, rs200622913, rs367645544, rs371979169, rs1441405400, rs377288128, rs1567235731, rs761004881, rs992599408, rs200893645, rs892836302, rs751763127, rs199964506, rs139023249, rs567024433, rs753191794, rs754630934, rs780056230, rs532872913, rs1566857785, rs772574630, rs370691735, rs373413299, rs759949044, rs775906033, rs1567240933, rs779268463, rs1567253059, rs369246005, rs750201337, rs780704306, rs202140253, rs201420241, rs201221837, rs761390620, rs369222777, rs377624442, rs761547558, rs775300751, rs752846417, rs1439048896, rs1595549414, rs753622466, rs759551484, rs776720726, rs765542021, rs200313634, rs1324382972, rs747970625, rs753712777, rs773784804, rs777760026, rs780640652, rs769453242, rs200709496, rs1274128199, rs550824274, rs768607761, rs1595957329, rs758679094, rs374585350, rs571025757, rs1596018951, rs757410936, rs374841951, rs200288877, rs1596035220, rs1596036055, rs1423994631, rs1596036635, rs759190039, rs942287498, rs768387060, rs1412149237, rs541189878, rs748718316, rs746481657, rs1385551494, rs1188037949, rs371761769, rs766854398, rs369168320, rs200721037, rs372903924, rs779706127, rs769067753, rs1202296934, rs372825727, rs1596361332, rs200542900, rs200246566, rs755555885, rs376553827, rs766762265, rs551472479, rs1342260343, rs749674166, rs200346049, rs200275874, rs1596670092, rs376792088, rs1024556759, rs199774214, rs777460190, rs752657728, rs760323861, rs772825862, rs1596844876, rs896349674, rs767089690, rs1596924208, rs372530911, rs760780316, rs532925135, rs377371320, rs770201518, rs1475380781, rs766901337, rs994746145, rs1597079990, rs752422188, rs373984848, rs367640896, rs1417754004, rs377008103, rs549279246, rs374675684, rs1597000124, rs545597409, rs201164828, rs190650629, rs543509946, rs1044129, rs201243902, rs760794454, rs61748999, rs377533350, rs199726068, rs145097742, rs143407858, rs766886794, rs201264890, rs372693148, rs770156777, rs3751641, rs368394901, rs200006806, rs377229802, rs187632363, rs369324246, rs191573523, rs541322440, rs11857026, rs189409991, rs115967801, rs368338031, rs1204903519, rs58775107, rs767902428, rs371505693, rs763303513, rs531084938, rs373312009, rs201672415, rs187165112, rs765344937, rs541972511, rs375009869, rs778205832, rs368476028, rs188476557, rs898192253, rs1596294514, rs369591701, rs746856794, rs1595791362, rs780714493, rs752550511, rs536158607, rs1596022012, rs200517335, rs370300379, rs368742527, rs763452753, rs777658408, rs945157767, rs758219464, rs574080321, rs149247828, rs185801690, rs74005925, rs144417845, rs1278028525, rs1595902210, rs1032258547, rs372929421, rs771772947, rs1019625776, rs764724739, rs377264013, rs757123345, rs780010155, rs538327874, rs1596526066, rs1250990985, rs765087383, rs186084318, rs775648968, rs369041765, rs202170755, rs569074460, rs763332893, rs768641537, rs776534103, rs1595668424, rs537373426, rs779754319, rs1595957366, rs1596021902, rs756679547, rs747408262, rs946782158, rs771068696, rs778179200, rs1596343898, rs1452135793, rs763362837, rs374363426, rs377282056, rs1201772266, rs748419368, rs377281161, rs868781162, rs1236215905, rs1346473227, rs1596418008, rs1595668505, rs916564375, rs1596313377, rs770665101, rs552370646, rs192358229, rs765702597, rs746777116, rs757805592, rs368487002, rs201852803, rs189331895, rs374572025, rs1595509178, rs750701373, rs1595902112, rs752015882, rs764599185, rs1566904570, rs1281447838, rs1596258502, rs754179311, rs749172404, rs1033099305, rs1596518868, rs1596588961, rs778158975, rs1596804345, rs1596837665, rs1597038714, rs1244939098, rs372099114, rs375998723, rs761781474, rs1467070057, rs370938489, rs534756978, rs553041018, rs868124984, rs771648147, rs772848050, rs202001689, rs745473265, rs374380667, rs756680726, rs964229276, rs774736714, rs374984544, rs372568152, rs2061111187, rs2061185962, rs1464769762, rs780712251, rs944419972, rs867518878, rs2061506739, rs757627554, rs766607821, rs2062111629, rs367755953, rs1441433888, rs202225145, rs201954117, rs541060757, rs763874440, rs2063205205, rs1417583973, rs372149967, rs760950887, rs376032202, rs1373558975, rs534126465, rs756272113, rs561525049, rs759365540, rs766712025, rs368930817, rs771787332, rs1211168792, rs750171875, rs2068053416, rs201082522, rs1434123396, rs752463552, rs747474248, rs763616243, rs750760036, rs754866375, rs2070235536, rs1353768684, rs1933408860, rs1488174946, rs2071683490, rs867153299, rs2071688750, rs772909971, rs763223227, rs2074306451, rs923528632, rs555061771, rs769503316, rs911946537, rs764702884, rs1278560286, rs778606179, rs201678035, rs755221573, rs1323235127, rs781316953, rs763084437, rs374140172, rs776225973, rs372999570, rs539110280, rs753107741, rs376839056, rs372365285, rs775076044, rs1014332640, rs555103509, rs202096363, rs778736021, rs1040889450, rs541643213, rs747112237, rs2073772349, rs752704653, rs370757624, rs2058591816, rs1248271851, rs749850251, rs758261396, rs2061113768, rs267604157, rs2052208538, rs2056574150, rs2058743774, rs752181610, rs768041967, rs748947513, rs2061188561, rs778637615, rs202160360, rs765617465, rs2066262816, rs1295193017, rs374086691, rs372756613, rs2074668657, rs1005334198, rs781646279, rs2076471810, rs367775699, rs2076946853, rs558254515, rs2078146981, rs1322987678, rs573502706, rs2078179226, rs1313607569, rs986253821, rs1307962205, rs762795498, rs2056578798, rs754291567, rs750313484, rs1332431637, rs754047679, rs370535769, rs373688734, rs377529797, rs2062560335, rs201020040, rs748230905, rs375515948, rs1487780532, rs774393965, rs759581452, rs1320750197, rs752171274, rs767187763, rs1281440819, rs1473088041, rs750619066, rs778795375, rs2074662147, rs2074663035, rs1294722820, rs2076465059, rs377377472, rs2076654085, rs761472822, rs1314124125, rs776691651, rs557120958, rs1311433743, rs2078159290, rs781033822, rs1464762533, rs1890080876, rs1268379736, rs747788382, rs374964000, rs752717428, rs577554238, rs1353196691, rs534066569, rs1465936417, rs1254419062, rs200621978, rs763363972, rs781576341, rs375881628, rs1235900492, rs2063089220, rs1282040806, rs747723845, rs2065862490, rs374589971, rs1427581990, rs1313404758, rs760687309, rs2069910315, rs201466342, rs368537521, rs766980461, rs187608290, rs370636001, rs201327770, rs2078157787, rs2078163216, rs191637587, rs752948099, rs2078391818, rs1327424943, rs1596979504, rs2080127373, rs982194939, rs966003933, rs2061991996, rs199964676, rs1462278259, rs768262446, rs372615267, rs776894612, rs2077191516, rs764000824, rs765319074, rs375405552, rs769076393, rs371105087, rs753142811, rs2077393995, rs201894323, rs1485242342, rs201310633, rs771419772, rs572913737, rs770203359, rs2057491445, rs752007601, rs771548354, rs769499365, rs762645686, rs1372256555, rs561947889, rs376346877, rs754630341, rs757239023, rs763833348, rs372052194, rs377298605, rs1181544618, rs138445751, rs755738535, rs564412519, rs774589130, rs1449406965, rs2066160816, rs2068052281, rs1311822738, rs1323254560, rs764854998, rs533878383, rs2071123542, rs1052040358, rs568295672, rs1425978893, rs776639416, rs777159610, rs759037751, rs200295482, rs201512313, rs1333654801, rs111761846, rs747261018, rs2078190891, rs2078620314, rs775356788, rs764029640	RCV001322199 RCV001319168 RCV001324453 RCV001312642 RCV001312956 RCV001322186 RCV001317999 RCV001315367 RCV001313781 RCV001318624 RCV001326572 RCV001313145 RCV001322370 RCV001312857 RCV001327275 RCV001321817 RCV001315410 RCV001314864 RCV001314270 RCV001327851 RCV001312691 RCV001320959 RCV001315482 RCV001323697 RCV001319053 RCV001321574 RCV001327015 RCV001316227 RCV001325507 RCV001318252 RCV001326142 RCV001322471 RCV001324601 RCV001314068 RCV001319171 RCV001324465 RCV001312526 RCV001326789 RCV001315347 RCV001326225 RCV001321472 RCV001312640 RCV001366210 RCV001350012 RCV001346783 RCV001337959 RCV001341769 RCV001348081 RCV001341236 RCV001340346 RCV001339809 RCV001342213 RCV001340752 RCV001341659 RCV001340627 RCV001346165 RCV001352471 RCV001344181 RCV001337621 RCV001343997 RCV001350183 RCV001343759 RCV001343199 RCV001349159 RCV001350013 RCV001349540 RCV001347519 RCV001348915 RCV001348137 RCV001351413 RCV001339733 RCV001344832 RCV001343658 RCV001351376 RCV001346384 RCV001344885 RCV001348603 RCV001337576 RCV001340249 RCV001343288 RCV001345726 RCV001352058 RCV001349105 RCV001342458 RCV001346070 RCV001351163 RCV001341481 RCV001339735 RCV001344503 RCV001337488 RCV001350034 RCV001347609 RCV001346776 RCV001342858 RCV001360593 RCV001361822 RCV001371975 RCV001361938 RCV001364728 RCV001362826 RCV001366610 RCV001362847 RCV001358901 RCV001364097 RCV001366715 RCV001367731 RCV001361951 RCV001368212 RCV001373589 RCV001360581 RCV001360820 RCV001363404 RCV001369625 RCV001367804 RCV001367869 RCV001369112 RCV001359174 RCV001367778 RCV001370085 RCV001372518 RCV001365386 RCV001371016 RCV001364753 RCV001373307 RCV001374039 RCV001371681 RCV001366155 RCV001373702 RCV001373422 RCV001372804 RCV001367527 RCV001359922 RCV001363297 RCV001363612 RCV001414637 RCV001396333 RCV001416269 RCV001405224 RCV001400222 RCV001396439 RCV001412471 RCV001394710 RCV001417956 RCV001401900 RCV001412139 RCV001408536 RCV001418185 RCV001410612 RCV001406894 RCV001417201 RCV001400347 RCV001414156 RCV001393411 RCV001409673 RCV001417931 RCV001393794 RCV001405582 RCV001410380 RCV001416840 RCV001413653 RCV001391979 RCV001413540 RCV001412593 RCV001406896 RCV001415462 RCV001406665 RCV001401964 RCV001410062 RCV001415309 RCV001394771 RCV001401749 RCV001396064 RCV001394607 RCV001397521 RCV001405787 RCV001393181 RCV001400834 RCV001398095 RCV001396035 RCV001404582 RCV001392676 RCV001401648 RCV001423962 RCV001437273 RCV001447581 RCV001441423 RCV001441847 RCV001444831 RCV001421715 RCV001447892 RCV001424007 RCV001441916 RCV001446130 RCV001434110 RCV001434532 RCV001439463 RCV001440988 RCV001446446 RCV001430108 RCV001446440 RCV001443738 RCV001434287 RCV001437679 RCV001428068 RCV001424889 RCV001422600 RCV001442747 RCV001448315 RCV001442454 RCV001439479 RCV001423354 RCV001434928 RCV001446180 RCV001447625 RCV001425162 RCV001437299 RCV001433374 RCV001428022 RCV001427375 RCV001444433 RCV001431433 RCV001424708 RCV001436005 RCV001442495 RCV001429704 RCV001447082 RCV001439674 RCV001446747 RCV001425725 RCV001440552 RCV001435137 RCV001448592 RCV001458636 RCV001460885 RCV001464059 RCV001466391 RCV001462129 RCV001470580 RCV001456210 RCV001477750 RCV001468647 RCV001457455 RCV001454485 RCV001450903 RCV001456585 RCV001457882 RCV001469072 RCV001455560 RCV001462811 RCV001465200 RCV001464871 RCV001462910 RCV001456244 RCV001462918 RCV001463495 RCV001453332 RCV001452096 RCV001473422 RCV001470384 RCV001474621 RCV001460132 RCV001472402 RCV001469440 RCV001464941 RCV001476717 RCV001458741 RCV001477862 RCV001455524 RCV001450795 RCV001450811 RCV001466402 RCV001477122 RCV001455604 RCV001469442 RCV001476819 RCV001462581 RCV001453103 RCV001450251 RCV001474646 RCV001460637 RCV001466843 RCV001467221 RCV001453806 RCV001477282 RCV001463520 RCV001452023 RCV001490774 RCV001493489 RCV001482590 RCV001500984 RCV001484383 RCV001503395 RCV001490321 RCV001495532 RCV001502906 RCV001482478 RCV001482591 RCV001495623 RCV001492299 RCV001497150 RCV001485941 RCV001501999 RCV001480509 RCV001484097 RCV001489978 RCV001502871 RCV001483424 RCV001505209 RCV001501476 RCV001490775 RCV001499249 RCV001495823 RCV001498171 RCV001493518 RCV001496791 RCV001488979 RCV001479214 RCV001493068 RCV001486210 RCV001481852 RCV001480992 RCV001481682 RCV001488557 RCV001498925 RCV001479526 RCV001488437 RCV001490827 RCV001489804 RCV001502019 RCV001494846 RCV001485159 RCV001494270 RCV001491769 RCV001478587 RCV001487868 RCV001506012 RCV001489267 RCV001488405 RCV001479684 RCV001485727 RCV001484075 RCV001513554 RCV001521921 RCV001514950 RCV001515455 RCV001521922 RCV001515456 RCV001521870 RCV001515626 RCV001522545 RCV001521923 RCV001519007 RCV001521924 RCV001518908 RCV001521925 RCV001516025 RCV001521926 RCV001522234 RCV001515457 RCV001521927 RCV001521928 RCV001511880 RCV001511881 RCV001515702 RCV002073119 RCV002073122 RCV001959594 RCV002027929 RCV001949152 RCV001919913 RCV002032063 RCV001930589 RCV001900049 RCV001992162 RCV002019329 RCV001937435 RCV001985283 RCV001952016 RCV001916576 RCV001901148 RCV002018721 RCV002014928 RCV001984898 RCV001943839 RCV001978520 RCV001874177 RCV002034929 RCV002025109 RCV002009496 RCV001877829 RCV002001199 RCV001952518 RCV002039311 RCV002039475 RCV002046737 RCV001937672 RCV001921965 RCV001978180 RCV002187678 RCV002118466 RCV002104679 RCV002115672 RCV002124643 RCV002158829 RCV002108412 RCV002200107 RCV002139187 RCV002109870 RCV002173952 RCV002164079 RCV002208082 RCV002209623 RCV002161735 RCV002219025 RCV002107619 RCV002081817 RCV002074806 RCV002122644 RCV002196049 RCV002087849 RCV002128228 RCV002105133 RCV002149093 RCV003071510 RCV002686212 RCV002755537 RCV002740723 RCV002952570 RCV002957754 RCV003015382 RCV002991443 RCV000693784 RCV003592596 RCV003591600 RCV003756288 RCV003867003 RCV000951367 RCV001086314 RCV002060211 RCV000560871 RCV001442591 RCV000526731 RCV000550799 RCV000539537 RCV000556837 RCV000555548 RCV001498855 RCV000543655 RCV000551858 RCV000528783 RCV000538508 RCV000541603 RCV000551935 RCV000544584 RCV000559395 RCV000537924 RCV000557697 RCV000550754 RCV000525065 RCV000539774 RCV000549974 RCV000540122 RCV000538740 RCV000548951 RCV000547947 RCV000526774 RCV000541534 RCV000532635 RCV000558024 RCV000546540 RCV000550675 RCV000534593 RCV000558367 RCV000534782 RCV000552941 RCV000560049 RCV000529288 RCV000544048 RCV000542986 RCV000559521 RCV000536477 RCV000551377 RCV000525248 RCV000531497 RCV000547748 RCV000540473 RCV000524695 RCV000556116 RCV001473249 RCV000535297 RCV001426485 RCV000527862 RCV000552523 RCV000554066 RCV000541249 RCV000543694 RCV000553691 RCV000526390 RCV000554692 RCV000532569 RCV000542886 RCV000530382 RCV000546065 RCV000534211 RCV000535995 RCV000533150 RCV000545200 RCV000529987 RCV000539576 RCV000554331 RCV000536691 RCV000546889 RCV000528985 RCV001083494 RCV000541775 RCV000545852 RCV000555977 RCV000538572 RCV000531976 RCV000547292 RCV000545960 RCV000558707 RCV000537467 RCV001475509 RCV000541805 RCV000531344 RCV000549315 RCV000558938 RCV000530023 RCV000559875 RCV000528818 RCV000540909 RCV000552741 RCV000553450 RCV000531164 RCV000538729 RCV000531223 RCV000558258 RCV000529498 RCV000544392 RCV000558500 RCV000536968 RCV000536153 RCV000525161 RCV000535468 RCV000550354 RCV000554869 RCV000527290 RCV000545273 RCV000547556 RCV000532366 RCV000528253 RCV000547111 RCV000530449 RCV000557249 RCV000559843 RCV000534177 RCV000549301 RCV000559069 RCV000527538 RCV000531801 RCV000557053 RCV000535353 RCV000542273 RCV000556221 RCV000542759 RCV000556677 RCV000527039 RCV000551974 RCV000555638 RCV000529400 RCV000536127 RCV000529748 RCV000524625 RCV000528415 RCV000544508 RCV000559724 RCV000538031 RCV000553337 RCV000550866 RCV001409496 RCV000537205 RCV000528767 RCV000547666 RCV000537966 RCV001396170 RCV000548329 RCV000528427 RCV000532291 RCV000547163 RCV000557435 RCV000550009 RCV000553075 RCV000545667 RCV000537405 RCV000552139 RCV000526175 RCV000533096 RCV000560479 RCV000543432 RCV000532190 RCV000534386 RCV000540335 RCV000546573 RCV000549632 RCV000548700 RCV000534560 RCV000549483 RCV000542162 RCV000637154 RCV000637156 RCV000637136 RCV000637072 RCV000637103 RCV000637196 RCV000637107 RCV000637128 RCV000637233 RCV000637139 RCV000637173 RCV001396194 RCV000637070 RCV000637097 RCV000637261 RCV000637078 RCV000637073 RCV000637166 RCV000637204 RCV000637231 RCV000637085 RCV000637123 RCV000637234 RCV001495308 RCV000637090 RCV000637169 RCV000637099 RCV000637105 RCV000637149 RCV000637160 RCV000637239 RCV000637249 RCV000637079 RCV000637279 RCV000637131 RCV000637182 RCV000637212 RCV000637163 RCV000637277 RCV000637077 RCV000637200 RCV000637236 RCV000637170 RCV000637188 RCV000637184 RCV000637276 RCV000637220 RCV000637237 RCV000637171 RCV000637157 RCV000637096 RCV000637252 RCV000637109 RCV000637191 RCV000637080 RCV000637140 RCV000637138 RCV000637284 RCV000637121 RCV000637133 RCV000637259 RCV000637113 RCV000637256 RCV000637242 RCV000637094 RCV000637246 RCV000637074 RCV000637209 RCV000637264 RCV000637134 RCV001443557 RCV000637192 RCV000637132 RCV000637168 RCV000637126 RCV000637087 RCV000637274 RCV000637095 RCV000637268 RCV000637206 RCV000637179 RCV000637167 RCV000637235 RCV001429156 RCV000637240 RCV000637201 RCV000637117 RCV001472831 RCV000637098 RCV000637119 RCV000637181 RCV000637111 RCV000637146 RCV000637214 RCV000637161 RCV000637100 RCV000637241 RCV000637248 RCV000637159 RCV000637155 RCV000637106 RCV000637115 RCV000637081 RCV000637084 RCV000637127 RCV000637148 RCV000637150 RCV000637271 RCV000637218 RCV000637195 RCV000637219 RCV000637243 RCV000637147 RCV000637122 RCV000637088 RCV000637102 RCV001521954 RCV001470608 RCV000686918 RCV000686330 RCV000700125 RCV000697175 RCV000705939 RCV000691675 RCV000688232 RCV000690028 RCV000701745 RCV000699199 RCV000688963 RCV000688312 RCV000685486 RCV000685590 RCV000694097 RCV000692913 RCV000689020 RCV000693745 RCV000698397 RCV000699743 RCV000700915 RCV000699810 RCV000698013 RCV000696506 RCV000700495 RCV000694227 RCV000703377 RCV000697234 RCV000690866 RCV000703503 RCV000688273 RCV000693185 RCV000705013 RCV000703037 RCV000704141 RCV000697351 RCV000703650 RCV000691789 RCV000693419 RCV000706076 RCV000706243 RCV000685525 RCV000699790 RCV000699213 RCV000706366 RCV000706951 RCV000699249 RCV000696583 RCV000705886 RCV000705966 RCV000701561 RCV000686873 RCV000695330 RCV000685136 RCV000701649 RCV000704747 RCV000688787 RCV000703515 RCV000702755 RCV000702707 RCV000692435 RCV000691414 RCV000707410 RCV000703719 RCV000704230 RCV000692529 RCV000700978 RCV000700038 RCV000688649 RCV000705885 RCV000692476 RCV000688786 RCV000699618 RCV000700578 RCV000685782 RCV000690091 RCV000697828 RCV000691742 RCV000687509 RCV000687752 RCV000696780 RCV000687894 RCV000687347 RCV000694153 RCV000692697 RCV000707411 RCV000697665 RCV000687189 RCV000703149 RCV000800449 RCV000814442 RCV000814991 RCV000814898 RCV000792016 RCV000815246 RCV000792647 RCV000799148 RCV000816966 RCV000807025 RCV000804722 RCV000813710 RCV000792497 RCV000798501 RCV000797470 RCV000801379 RCV000804337 RCV000794799 RCV000815696 RCV000809046 RCV000810830 RCV000802972 RCV000796814 RCV000819662 RCV000808512 RCV000815135 RCV000807067 RCV000801324 RCV000823909 RCV000793886 RCV000801745 RCV000814717 RCV000820336 RCV000823162 RCV000817685 RCV000818590 RCV000811325 RCV000818591 RCV000809442 RCV000811427 RCV000817412 RCV000808809 RCV000799596 RCV000818892 RCV000823378 RCV000817777 RCV000815865 RCV000800501 RCV000791569 RCV000794980 RCV000798045 RCV000792401 RCV000819770 RCV000818871 RCV000802530 RCV000818623 RCV000806843 RCV000815808 RCV000798939 RCV000798633 RCV000817747 RCV000793735 RCV000814897 RCV000815301 RCV000811205 RCV000792623 RCV000823891 RCV000824008 RCV000794224 RCV000817644 RCV000810991 RCV000799292 RCV000810170 RCV000806789 RCV000822339 RCV000821596 RCV000818094 RCV000799077 RCV000813074 RCV000793159 RCV000804296 RCV000821642 RCV000804090 RCV000809538 RCV000816702 RCV000815423 RCV000811446 RCV000819964 RCV000802049 RCV000819176 RCV000820535 RCV000802840 RCV000822673 RCV000809355 RCV000810252 RCV000799406 RCV000878360 RCV000877882 RCV000878322 RCV000878587 RCV001521929 RCV000878676 RCV000959211 RCV000945999 RCV000950336 RCV000955106 RCV000952060 RCV000950922 RCV000945951 RCV000952627 RCV002547223 RCV001505364 RCV000946364 RCV000954377 RCV000950324 RCV000945993 RCV000950902 RCV000959714 RCV000960776 RCV001475496 RCV000972018 RCV000960778 RCV000960811 RCV001511574 RCV001452022 RCV001435841 RCV001470120 RCV000966577 RCV001397522 RCV000884782 RCV000891500 RCV000882955 RCV000887632 RCV000883293 RCV000890996 RCV000883294 RCV000887495 RCV001505848 RCV000889236 RCV000892296 RCV000891013 RCV000905129 RCV002065611 RCV000904520 RCV001439038 RCV000895329 RCV001454195 RCV000902851 RCV001479560 RCV000908875 RCV000909793 RCV000898114 RCV000897974 RCV000896329 RCV000902826 RCV000904900 RCV000898754 RCV000898356 RCV000898450 RCV000907904 RCV000897011 RCV000895599 RCV001484260 RCV001439997 RCV000917903 RCV002544966 RCV001415339 RCV000924129 RCV000920336 RCV001418879 RCV000923236 RCV001473291 RCV000926814 RCV000915609 RCV001460884 RCV001492635 RCV001392690 RCV000919627 RCV000914150 RCV000926066 RCV000926134 RCV000918606 RCV001462643 RCV001412209 RCV001484268 RCV001481423 RCV001461790 RCV001478224 RCV001404218 RCV000943969 RCV001505423 RCV001393647 RCV000931028 RCV000931275 RCV000935250 RCV001435477 RCV001503273 RCV001465385 RCV000928858 RCV000933269 RCV001492709 RCV001394050 RCV001440412 RCV001406969 RCV001429670 RCV001488072 RCV001432827 RCV001399340 RCV000940462 RCV001394064 RCV001428298 RCV001430593 RCV000945444 RCV000955078 RCV000951749 RCV000946002 RCV000951611 RCV000951636 RCV000945877 RCV001409921 RCV001410513 RCV000978923 RCV001472917 RCV001407890 RCV001490186 RCV000981149 RCV001502430 RCV001453447 RCV001418014 RCV001457891 RCV001412280 RCV000983099 RCV001443649 RCV001483457 RCV001430150 RCV001407445 RCV001423901 RCV000981868 RCV001406073 RCV001063110 RCV001071177 RCV001061351 RCV001069559 RCV001046469 RCV001042233 RCV001064869 RCV001047064 RCV001071797 RCV001035155 RCV001052480 RCV001047300 RCV001051102 RCV001042549 RCV001050026 RCV001039950 RCV001061154 RCV001039898 RCV001060055 RCV001071968 RCV001060239 RCV001035575 RCV001037772 RCV001056179 RCV001056762 RCV001052152 RCV001071954 RCV001061427 RCV001047918 RCV001064367 RCV001050786 RCV001054781 RCV001039595 RCV001070565 RCV001052023 RCV001058817 RCV001063365 RCV001050489 RCV001046411 RCV001036115 RCV001054656 RCV001038900 RCV001070103 RCV001042260 RCV001064330 RCV001051510 RCV001051054 RCV001037277 RCV001069246 RCV001070802 RCV001066147 RCV001046794 RCV001050586 RCV001042992 RCV001051615 RCV001051392 RCV001065376 RCV001048024 RCV001054121 RCV001045983 RCV001044467 RCV001038696 RCV001046442 RCV001066598 RCV001065802 RCV001057658 RCV001050426 RCV001056763 RCV001036988 RCV001044612 RCV001065759 RCV001034865 RCV001071760 RCV001047366 RCV001039815 RCV001043843 RCV001052795 RCV001054219 RCV001047598 RCV001045014 RCV001067611 RCV001069136 RCV001045128 RCV001051469 RCV001070321 RCV001058036 RCV001041247 RCV001049241 RCV001035728 RCV001049985 RCV001068475 RCV001059870 RCV001049124 RCV001063844 RCV001042179 RCV001050518 RCV001052741 RCV001061012 RCV001049248 RCV001068829 RCV001050172 RCV001072010 RCV001070791 RCV001072089 RCV001055330 RCV001215388 RCV001217309 RCV001215482 RCV001215631 RCV001217455 RCV001215931 RCV001219861 RCV001220919 RCV001219287 RCV001220469 RCV001224038 RCV001221784 RCV001220963 RCV001220519 RCV001215520 RCV001218898 RCV001217237 RCV001224877 RCV001224270 RCV001214919 RCV001217638 RCV001220194 RCV001217326 RCV001224135 RCV001219899 RCV001223332 RCV001217494 RCV001223121 RCV001217173 RCV001221560 RCV001219153 RCV001205345 RCV001207425 RCV001207988 RCV001205872 RCV001212574 RCV001207866 RCV001206191 RCV001204665 RCV001209640 RCV001202571 RCV001211151 RCV001201985 RCV001205142 RCV001211905 RCV001202001 RCV001212051 RCV001213894 RCV001210610 RCV001204224 RCV001208280 RCV001207964 RCV001207664 RCV001206917 RCV001210358 RCV001208166 RCV001201948 RCV001206327 RCV001203888 RCV001207019 RCV001205710 RCV001207020 RCV001208920 RCV001212754 RCV001209710 RCV001202013 RCV001204391 RCV001213398 RCV001212429 RCV001205953 RCV001224911 RCV001223031 RCV001236865 RCV001231032 RCV001226102 RCV001236739 RCV001234041 RCV001227224 RCV001236321 RCV001236641 RCV001236685 RCV001231967 RCV001236097 RCV001236132 RCV001232575 RCV001235483 RCV001235859 RCV001228137 RCV001236630 RCV001226308 RCV001238808 RCV001238506 RCV001235276 RCV001234546 RCV001237615 RCV001226468 RCV001236086 RCV001237575 RCV001234035 RCV001227097 RCV001229813 RCV001229802 RCV001227416 RCV001232634 RCV001226980 RCV001232132 RCV001237362 RCV001228804 RCV001235595 RCV001237086 RCV001240447 RCV001243934 RCV001244871 RCV001238869 RCV001242218 RCV001246570 RCV001246100 RCV001245131 RCV001243769 RCV001247891 RCV001245300 RCV001242706 RCV001245836 RCV001235429 RCV001234547 RCV001226440 RCV001228637 RCV001233143 RCV001242869 RCV001367490 RCV001303620 RCV001298476 RCV001308519 RCV001304968 RCV001299761 RCV001308612 RCV001304675 RCV001307867 RCV001301967 RCV001296135 RCV001296386 RCV001301169 RCV001294818 RCV001300914 RCV001297486 RCV001306636 RCV001295608 RCV001307023 RCV001299359 RCV001299525 RCV001308998 RCV001306861 RCV001308292 RCV001305042 RCV001296939 RCV001300755 RCV001307918 RCV001304185 RCV001309628 RCV001303513 RCV001304550 RCV001302022 RCV001294525 RCV001302206 RCV001300983 RCV001302569 RCV001308137 RCV001303911 RCV001304710 RCV001301390 RCV001299365 RCV001299759 RCV001298551 RCV001301500 RCV001305428 RCV001296728
Familial cancer of breast	Conflicting classifications of pathogenicity	rs200294137	RCV005901733
Familial prostate cancer	Likely benign	rs375622890	RCV005933448
Fetal akinesia deformation sequence 1	Uncertain significance	rs1466702657	RCV000855509
Flexion contracture	Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs199500216, rs200346049, rs549279246, rs1314283337	RCV001007845 RCV001007818 RCV001007854 RCV001007853
Gastric cancer	Uncertain significance; Benign; Likely benign	rs772160575, rs117754976, rs2304386, rs79305633, rs200830195, rs1268379736	RCV005911159 RCV005928264 RCV005901388 RCV005901384 RCV005900171 RCV005909064
Hepatocellular carcinoma	Benign	rs2293028, rs2303310, rs79305633	RCV005909605 RCV005918775 RCV005901381
Lung cancer	Benign	rs41279208	RCV005927854
Malignant tumor of esophagus	Benign; Likely benign	rs117754976, rs2304386, rs146201205, rs79305633	RCV005928261 RCV005901387 RCV005901378 RCV005901382
Melanoma	Benign	rs79305633	RCV005901385
Monomelic amyotrophy	Likely benign	rs545597409	RCV003235429
Nonpapillary renal cell carcinoma	Uncertain significance	rs191637587	RCV005909078
Ovarian serous cystadenocarcinoma	Benign; Likely benign	rs117754976, rs146201205	RCV005928265 RCV005901379
Premature ovarian failure	Conflicting classifications of pathogenicity; Uncertain significance	rs753104655, rs1189945732, rs2066768594	RCV001270227 RCV001270226 RCV001270228
RYR3-related disorder	Likely benign; Uncertain significance; Benign; Conflicting classifications of pathogenicity	rs780189239, rs377333580, rs183464547, rs1421701855, rs200841538, rs1382454330, rs2508811179, rs756165310, rs764639699, rs1156880664, rs777687584, rs1269016605, rs1307984411, rs758364996, rs1050116892, rs781446892, rs2504757645, rs767631260, rs28655866, rs375622890, rs61749016, rs146838868, rs202244063, rs199638420, rs115119086, rs61996336, rs368370540, rs138901366, rs146892882, rs139287308, rs112521485, rs41279214, rs74437672, rs61996335, rs377437662, rs147149598, rs78825800, rs80354707, rs202185923, rs181264765, rs149242033, rs201561672, rs188257094, rs190035689, rs150799181, rs139568967, rs199745365, rs200401387, rs202181075, rs189410371, rs182257230, rs374117753, rs549685153, rs200309704, rs199615159, rs189282419, rs200830195, rs199645058, rs1481136779, rs200893645, rs373984848, rs201164828, rs190650629, rs189409991, rs371505693, rs116926961, rs374363426, rs749413810, rs771548354	RCV003938714 RCV003908580 RCV003973294 RCV003921009 RCV003973315 RCV003392789 RCV003420858 RCV003410380 RCV003400134 RCV003966460 RCV003924151 RCV003894491 RCV003913962 RCV003951997 RCV003971928 RCV003949410 RCV003944781 RCV003946958 RCV003971691 RCV003971431 RCV003902509 RCV003942774 RCV003915528 RCV003942775 RCV003935435 RCV003915533 RCV003925621 RCV003935436 RCV003905364 RCV003905365 RCV003905366 RCV003915531 RCV003905367 RCV003915532 RCV003935439 RCV003925625 RCV003983110 RCV003915530 RCV003960292 RCV003935437 RCV003925622 RCV003960293 RCV003962494 RCV003935438 RCV003942776 RCV003925624 RCV003925623 RCV003915526 RCV003915527 RCV003905363 RCV003915529 RCV003960291 RCV003937918 RCV003965341 RCV003980234 RCV003953130 RCV003965338 RCV003953129 RCV003420232 RCV003953245 RCV003908107 RCV003938383 RCV003908361 RCV003926129 RCV003936021 RCV003902944 RCV003903076 RCV003978104 RCV003405522
RYR3-related Epileptic encephalopathy	Uncertain significance	rs1326359705, rs2152815011, rs550033490, rs763523192, rs745481097, rs761547558, rs200288877, rs376553827, rs770718730, rs368923826, rs751132721	RCV001839282 RCV001839357 RCV001839362 RCV001839376 RCV001839385 RCV004799240 RCV002275137 RCV002227497 RCV004799340 RCV004799451 RCV004799601
Sarcoma	Benign	rs41279208, rs117754976	RCV005927853 RCV005928263
See cases	Uncertain significance; Conflicting classifications of pathogenicity	rs982440028, rs1018806149, rs2152976640, rs753104655, rs765872802, rs183923528, rs2078161593	RCV001780248 RCV001591733 RCV001784116 RCV001198785 RCV001420554 RCV001197271 RCV001196827
Uterine carcinosarcoma	Benign	rs11853872, rs2293028, rs12914825, rs117754976, rs2279662	RCV005914327 RCV005909606 RCV005909607 RCV005928266 RCV005926190
Uterine corpus endometrial carcinoma	Benign; Uncertain significance	rs117754976, rs79305633, rs374921732	RCV005928267 RCV005901386 RCV005900166
Uveal melanoma	Benign	rs2303310, rs2279662	RCV005918776 RCV005926189

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	34062866
Amyotrophic Lateral Sclerosis	Associate	35355568
Arthrogryposis	Associate	31230720
Atherosclerosis	Associate	20009918, 22627881, 24423397, 24561552
Blast Crisis	Associate	33557955
Breast Neoplasms	Associate	21810988
Calcinosis	Associate	21810988
Cardio Renal Syndrome	Associate	37391705
Cardiovascular Diseases	Associate	20009918, 22664477
Carotid Artery Diseases	Associate	24423397
Cerebral Palsy	Associate	33557955
Cerebral Palsy Ataxic Autosomal Recessive	Associate	19096130
Cholangiocarcinoma	Associate	29408647
Chordoma	Associate	38012562
Cognition Disorders	Associate	33154391
Congenital contractural arachnodactyly	Associate	24561552
Congenital Hyperinsulinism	Associate	23869231
Coronary Disease	Associate	22664477, 36134646
Developmental Disabilities	Associate	33557955
Dystonia	Associate	33557955
Fetal akinesia syndrome X linked	Associate	31680123
Heart Failure	Associate	22664477, 36134646, 37391705
HIV Infections	Associate	20009918, 22627881, 24561552
Hypertension	Associate	22664477
Inflammation	Associate	33154391
Melanoma Cutaneous Malignant	Associate	30596980
Microsatellite Instability	Associate	33170334
Motor Neuron Disease	Associate	33557955
Muscular Diseases	Associate	20489141
Myasthenia Gravis Autoimmune Experimental	Associate	24719132
Myocardial Infarction	Associate	22664477
Myopathies Structural Congenital	Stimulate	19581603
Neoplasm Metastasis	Associate	29408647
Neoplasms	Associate	26250335
Neurodegenerative Diseases	Associate	35355568
Neuromuscular Diseases	Associate	31680123
Non Radiographic Axial Spondyloarthritis	Associate	36543524
Obsessive Compulsive Disorder	Associate	21691774
Osteitis Deformans	Associate	35355568
Osteoporosis	Associate	37874452
Pancreatitis Chronic	Associate	19096130
Post Acute COVID 19 Syndrome	Associate	37915075
Pre Eclampsia	Inhibit	20178461
Renal Insufficiency	Associate	37391705
Seizures	Associate	33557955
Spasms Infantile	Associate	29667327
Squamous Cell Carcinoma of Head and Neck	Associate	33737696
Stroke	Associate	24423397
Sudden Unexpected Death in Epilepsy	Associate	24372310
Urinary Bladder Neoplasms	Associate	35087173